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Ligand source activities (1 row/activity)

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Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Potency)	# tested GPCRs (Potency)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	25174150	9029	0	None	64	2	Human	10.2	pIC50	=	10.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099326	9029	0	None	64	2	Human	10.2	pIC50	=	10.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25191879	9038	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	599	18	2	5	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3cccc(F)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099335	9038	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	599	18	2	5	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3cccc(F)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	25191880	9035	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	587	18	2	6	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099332	9035	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	587	18	2	6	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192021	9026	0	None	223	2	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099323	9026	0	None	223	2	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192023	8446	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	625	18	2	7	7.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094346	8446	0	None	-	1	Human	9.7	pIC50	=	9.7	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	625	18	2	7	7.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	25192174	9034	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	586	18	2	5	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099331	9034	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	586	18	2	5	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	132379	111240	13	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneAntagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membrane	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111240	13	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membraneAntagonistic activity against LTB4 receptor using guinea pig (GP) spleen cell membrane	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	25192176	8447	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	626	18	2	8	7.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094347	8447	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	626	18	2	8	7.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	25192175	9037	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	588	18	2	7	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099334	9037	0	None	-	1	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	588	18	2	7	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cncnc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192022	3303	4	None	21	2	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	6158	3303	4	None	21	2	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	CHEMBL1098560	3303	4	None	21	2	Human	9.4	pIC50	=	9.4	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	23501721	9033	0	None	316	2	Human	9.3	pIC50	=	9.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099330	9033	0	None	316	2	Human	9.3	pIC50	=	9.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	25192325	9036	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	621	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccnc(Cl)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099333	9036	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	621	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccnc(Cl)c3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192326	8942	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	592	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1098550	8942	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	592	18	2	6	8.6	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccsc3)cc(-c3ccsc3)c2)c1CCC(=O)O	10.1021/jm1001919
	25192327	9040	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	624	18	2	6	8.2	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099337	9040	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	624	18	2	6	8.2	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	25192468	8449	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccccc3F)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094349	8449	0	None	-	1	Human	9.2	pIC50	=	9.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccccc3F)c2)c1CCC(=O)O	10.1021/jm1001919
	132379	111240	13	None	-	1	Human	9.1	pIC50	=	9.1	Functional	Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111240	13	None	-	1	Human	9.1	pIC50	=	9.1	Functional	Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.Concentration inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	25192471	8448	0	None	15	2	Human	8.9	pIC50	=	8.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094348	8448	0	None	15	2	Human	8.9	pIC50	=	8.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	10319829	25913	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135612	25913	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10341135	29175	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL138380	29175	0	None	-	1	Human	7.0	pIC50	=	7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10047140	27400	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL136960	27400	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	14946858	28948	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL138174	28948	0	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	6444688	186737	29	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	CHEMBL49302	186737	29	None	-	1	Human	6.0	pIC50	=	6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	10071290	27890	0	None	-	1	Human	5.0	pIC50	=	5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137303	27890	0	None	-	1	Human	5.0	pIC50	=	5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	25192022	3303	4	None	21	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	6158	3303	4	None	21	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	CHEMBL1098560	3303	4	None	21	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	10.1021/jm1001919
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonistic activity against human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity against human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00100a034
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonistic activity against human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity against human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00100a034
	10343923	27575	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137074	27575	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	10477988	27932	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137330	27932	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10364772	27949	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137341	27949	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	25192471	8448	0	None	15	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094348	8448	0	None	15	2	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	642	18	2	6	8.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm960088k
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm960088k
	46888200	9039	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	637	18	3	4	9.1	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4[nH]ccc4c3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099336	9039	0	None	-	1	Human	7.9	pIC50	=	7.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	637	18	3	4	9.1	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3cccc(F)c3)cc(-c3ccc4[nH]ccc4c3)c2)c1CCC(=O)O	10.1021/jm1001919
	10341242	27942	0	None	-	1	Human	5.9	pIC50	=	5.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	CHEMBL137336	27942	0	None	-	1	Human	5.9	pIC50	=	5.9	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	6450158	186591	14	None	-	1	Human	6.9	pIC50	=	6.9	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49210	186591	14	None	-	1	Human	6.9	pIC50	=	6.9	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	46888199	9032	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	696	18	2	8	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCCO4)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099329	9032	0	None	-	1	Human	6.9	pIC50	=	6.9	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	696	18	2	8	8.0	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCCO4)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	114999	3482	15	None	-	1	Human	6.9	pIC50	=	6.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	6156	3482	15	None	-	1	Human	6.9	pIC50	=	6.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	CHEMBL14823	3482	15	None	-	1	Human	6.9	pIC50	=	6.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	44382384	59230	0	None	-	1	Human	4.9	pIC50	=	4.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL171666	59230	0	None	-	1	Human	4.9	pIC50	=	4.9	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10092630	27613	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137104	27613	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10475503	27799	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137247	27799	0	None	-	1	Human	7.8	pIC50	=	7.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10023244	25957	1	None	-	1	Human	6.8	pIC50	=	6.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135671	25957	1	None	-	1	Human	6.8	pIC50	=	6.8	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44357534	26535	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136243	26535	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10406292	28184	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137504	28184	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9865985	28461	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137759	28461	0	None	-	1	Human	5.7	pIC50	=	5.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10427789	27732	0	None	-	1	Human	4.7	pIC50	=	4.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137201	27732	0	None	-	1	Human	4.7	pIC50	=	4.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	23501721	9033	0	None	316	2	Human	6.7	pIC50	=	6.7	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099330	9033	0	None	316	2	Human	6.7	pIC50	=	6.7	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	581	18	2	5	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O	10.1021/jm1001919
	9976757	28289	0	None	-	1	Human	7.7	pIC50	=	7.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137581	28289	0	None	-	1	Human	7.7	pIC50	=	7.7	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44382378	58561	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL168854	58561	0	None	-	1	Human	6.7	pIC50	=	6.7	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10474602	25774	0	None	-	1	Human	5.6	pIC50	=	5.6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL135434	25774	0	None	-	1	Human	5.6	pIC50	=	5.6	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	46888201	9041	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	654	19	2	7	8.2	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc4c(c3)OCO4)c2)cc1	10.1021/jm1001919
	CHEMBL1099338	9041	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	654	19	2	7	8.2	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc4c(c3)OCO4)c2)cc1	10.1021/jm1001919
	3368	1150	18	None	-3	2	Mouse	7.5	pIC50	=	7.5	Functional	Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorTested for antagonistic activity in mouse spleen membrane against LTB4 receptor	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	9867257	1150	18	None	-3	2	Mouse	7.5	pIC50	=	7.5	Functional	Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorTested for antagonistic activity in mouse spleen membrane against LTB4 receptor	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	CHEMBL51770	1150	18	None	-3	2	Mouse	7.5	pIC50	=	7.5	Functional	Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorTested for antagonistic activity in mouse spleen membrane against LTB4 receptor	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	10001576	28169	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137494	28169	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10046878	28221	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137531	28221	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	46888196	9028	0	None	-	1	Human	7.5	pIC50	=	7.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	640	20	2	6	8.5	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc(OC)cc3)c2)cc1	10.1021/jm1001919
	CHEMBL1099325	9028	0	None	-	1	Human	7.5	pIC50	=	7.5	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	640	20	2	6	8.5	COc1ccc(-c2cc(OCCCCCCc3cccc(OCCCC(=O)O)c3CCC(=O)O)cc(-c3ccc(OC)cc3)c2)cc1	10.1021/jm1001919
	44382275	59425	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL172457	59425	0	None	-	1	Human	5.5	pIC50	=	5.5	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	25192021	9026	0	None	223	2	Human	7.4	pIC50	=	7.4	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099323	9026	0	None	223	2	Human	7.4	pIC50	=	7.4	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	580	18	2	4	8.5	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)c2)c1CCC(=O)O	10.1021/jm1001919
	44382276	119810	0	None	-	1	Human	4.4	pIC50	=	4.4	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL352814	119810	0	None	-	1	Human	4.4	pIC50	=	4.4	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	9978895	118471	0	None	-	1	Human	7.4	pIC50	=	7.4	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL342416	118471	0	None	-	1	Human	7.4	pIC50	=	7.4	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	10021742	9365	4	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilizationAntagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilization	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9365	4	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilizationAntagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilization	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	44356239	27634	0	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonistic activity in human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity in human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	361	8	0	2	4.9	CN(CCc1ccccc1)C(=O)CC1=CC=C(OCc2ccccc2)CC1	10.1021/jm00100a034
	CHEMBL137121	27634	0	None	-	1	Human	5.3	pIC50	=	5.3	Functional	Antagonistic activity in human polymorphonuclear (PMN) LTB4 receptorAntagonistic activity in human polymorphonuclear (PMN) LTB4 receptor	ChEMBL	361	8	0	2	4.9	CN(CCc1ccccc1)C(=O)CC1=CC=C(OCc2ccccc2)CC1	10.1021/jm00100a034
	46888197	9030	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3cncnc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099327	9030	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3cncnc3)c2)c1CCC(=O)O	10.1021/jm1001919
	46888198	9031	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	668	18	2	8	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099328	9031	0	None	-	1	Human	8.3	pIC50	=	8.3	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	668	18	2	8	7.9	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	9934323	99789	0	None	-	1	Human	6.3	pIC50	=	6.3	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	CHEMBL288758	99789	0	None	-	1	Human	6.3	pIC50	=	6.3	Functional	The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsThe antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	10091738	27595	0	None	-	1	Human	6.2	pIC50	=	6.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137089	27595	0	None	-	1	Human	6.2	pIC50	=	6.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	46888202	8450	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	656	18	2	6	8.4	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1094350	8450	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	656	18	2	6	8.4	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc4c(c3)OCCO4)c2)c1CCC(=O)O	10.1021/jm1001919
	44382468	58779	0	None	-	1	Human	5.2	pIC50	=	5.2	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL169639	58779	0	None	-	1	Human	5.2	pIC50	=	5.2	Functional	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced ChemotaxisIn vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10430674	118833	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL344230	118833	0	None	-	1	Human	7.2	pIC50	=	7.2	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	25174150	9029	0	None	64	2	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099326	9029	0	None	64	2	Human	7.2	pIC50	=	7.2	Functional	Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challengeAntagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge	ChEMBL	582	18	2	6	7.3	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccncc3)c2)c1CCC(=O)O	10.1021/jm1001919
	44357546	116253	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	CHEMBL337563	116253	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	46888195	9027	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	616	18	2	4	8.7	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc(F)cc3)c2)c1CCC(=O)O	10.1021/jm1001919
	CHEMBL1099324	9027	0	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsAntagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins	ChEMBL	616	18	2	4	8.7	O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(F)cc3)cc(-c3ccc(F)cc3)c2)c1CCC(=O)O	10.1021/jm1001919
	122023	50523	56	None	1	3	Human	7.1	pIC50	=	7.1	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm960088k
	CHEMBL15766	50523	56	None	1	3	Human	7.1	pIC50	=	7.1	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm960088k
	CHEMBL45460	50523	56	None	1	3	Human	7.1	pIC50	=	7.1	Functional	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm960088k
	132379	111240	13	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg. Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111240	13	None	-	1	Human	8.1	pIC50	=	8.1	Functional	Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg. Antagonistic activity against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	3368	1150	18	None	3	2	Human	8.0	pIC50	=	8.0	Functional	Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneTested for antagonistic activity against LTB4 receptor in guinea pig spleen membrane	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	9867257	1150	18	None	3	2	Human	8.0	pIC50	=	8.0	Functional	Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneTested for antagonistic activity against LTB4 receptor in guinea pig spleen membrane	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	CHEMBL51770	1150	18	None	3	2	Human	8.0	pIC50	=	8.0	Functional	Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneTested for antagonistic activity against LTB4 receptor in guinea pig spleen membrane	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	10022413	27451	0	None	-	1	Human	6.1	pIC50	=	6.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136991	27451	0	None	-	1	Human	6.1	pIC50	=	6.1	Functional	Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesInhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10692884	187582	0	None	-	0	Human	8.0	pKi	=	8.0	Functional	Leukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNsLeukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNs	ChEMBL	409	10	1	3	5.1	CCN(CC)C(=O)/C=C(\C)c1ccc(OC(C)c2ccccc2)c(CCC(=O)O)c1	10.1021/jm980540v
	CHEMBL49866	187582	0	None	-	0	Human	8.0	pKi	=	8.0	Functional	Leukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNsLeukotriene B4 receptor antagonistic activity was measured by the inhibition of LTB4 induced [Ca2+] release from human PMNs	ChEMBL	409	10	1	3	5.1	CCN(CC)C(=O)/C=C(\C)c1ccc(OC(C)c2ccccc2)c(CCC(=O)O)c1	10.1021/jm980540v
	60490	205530	104	None	-8	2	Human	8.2	pIC50	=	8.2	Functional	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	Drug Central	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	None
	CHEMBL93	205530	104	None	-8	2	Human	8.2	pIC50	=	8.2	Functional	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	Drug Central	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	None
	71398	105958	37	None	3	2	Human	8.2	pIC50	=	8.2	Functional	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	Drug Central	302	5	4	4	3.6	C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1	None
	CHEMBL313972	105958	37	None	3	2	Human	8.2	pIC50	=	8.2	Functional	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	Drug Central	302	5	4	4	3.6	C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1	None
	6157	2889	16	None	-	1	Human	5.8	pIC50	=	5.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	6438358	2889	16	None	-	1	Human	5.8	pIC50	=	5.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	CHEMBL422420	2889	16	None	-	1	Human	5.8	pIC50	=	5.8	Functional	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	114999	3482	15	None	-	1	Human	6.1	pIC50	=	6.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	6156	3482	15	None	-	1	Human	6.1	pIC50	=	6.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	CHEMBL14823	3482	15	None	-	1	Human	6.1	pIC50	=	6.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	3368	1150	18	None	3	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	7714764
	9867257	1150	18	None	3	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	7714764
	CHEMBL51770	1150	18	None	3	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	7714764
	25192022	3303	4	None	21	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	20214997
	6158	3303	4	None	21	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	20214997
	CHEMBL1098560	3303	4	None	21	2	Human	8.1	pIC50	=	8.1	Functional	UnclassifiedUnclassified	Guide to Pharmacology	630	18	2	7	8.3	OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O	20214997
	177941	1558	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	2948	1558	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	CHEMBL329123	1558	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	DB12850	1558	40	None	-	1	Human	8.4	pIC50	=	8.4	Functional	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	6154	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	6154	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	9956189	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	9956189	627	0	None	-	1	Human	8.5	pIC50	=	8.5	Functional	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	6155	1153	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	9823886	1153	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	CHEMBL301829	1153	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	DB13053	1153	0	None	1318	2	Human	8.6	pIC50	=	8.6	Functional	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393

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Ligands					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity (Affinity)	# tested GPCRs (Affinity)	Species	p-value (-log)	Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	44379678	164370	0	None	-	0	Human	10.0	pIC50	=	10	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	527	14	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL422388	164370	0	None	-	0	Human	10.0	pIC50	=	10	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	527	14	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	44379453	57779	0	None	-	0	Human	9.8	pIC50	=	9.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	513	13	1	6	4.9	CCCc1c(OCCCOc2ccc(C(=O)N(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167350	57779	0	None	-	0	Human	9.8	pIC50	=	9.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	513	13	1	6	4.9	CCCc1c(OCCCOc2ccc(C(=O)N(C)C)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	15817161	57827	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	499	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167804	57827	0	None	-	0	Human	9.1	pIC50	=	9.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	499	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	9865985	28461	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137759	28461	0	None	-	0	Human	9.0	pIC50	=	9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	114999	3482	15	None	-	1	Human	9.0	pIC50	=	9	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/S0960-894X(01)80853-2
	6156	3482	15	None	-	1	Human	9.0	pIC50	=	9	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/S0960-894X(01)80853-2
	CHEMBL14823	3482	15	None	-	1	Human	9.0	pIC50	=	9	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/S0960-894X(01)80853-2
	204058	162907	5	None	-	1	Human	8.9	pIC50	=	8.9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm960088k
	CHEMBL419948	162907	5	None	-	1	Human	8.9	pIC50	=	8.9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm960088k
	196905	111141	8	None	-	0	Human	8.8	pIC50	=	8.8	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm960088k
	CHEMBL328492	111141	8	None	-	0	Human	8.8	pIC50	=	8.8	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm960088k
	2487	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	5280492	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL65061	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	DB12961	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	6444688	186737	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49302	186737	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	2487	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	5280492	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	CHEMBL65061	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	DB12961	2336	32	None	31	2	Human	8.7	pIC50	=	8.7	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00172a020
	11799000	16986	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	CHEMBL125611	16986	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	10385899	27200	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL136805	27200	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	9999755	26367	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136094	26367	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	44357534	26535	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136243	26535	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10071290	27890	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137303	27890	0	None	-	0	Human	8.0	pIC50	=	8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	196905	111141	8	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL328492	111141	8	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	11756030	58452	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3cocn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL168658	58452	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3cocn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	14946858	28948	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL138174	28948	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10407251	118576	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL342688	118576	0	None	-	0	Human	7.0	pIC50	=	7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	15666577	9111	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1ccsc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL110402	9111	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptors at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1ccsc1CCCc1ccccc1	10.1021/jm00095a011
	15666579	5551	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1ccsc1CCCc1ccc(Cl)cc1	10.1021/jm00095a011
	CHEMBL107760	5551	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1ccsc1CCCc1ccc(Cl)cc1	10.1021/jm00095a011
	15666578	7822	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1csc(CCCc2ccc(Cl)cc2)c1	10.1021/jm00095a011
	CHEMBL109015	7822	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	364	11	1	2	6.2	O=C(O)CCCCCCc1csc(CCCc2ccc(Cl)cc2)c1	10.1021/jm00095a011
	15666603	8054	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL109176	8054	1	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	330	11	1	2	5.5	O=C(O)CCCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	15666621	9152	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	406	12	1	2	7.2	O=C(O)CCCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL110707	9152	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	406	12	1	2	7.2	O=C(O)CCCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1	10.1021/jm00095a011
	44315785	14482	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	326	11	3	3	4.1	CCCCCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205307	14482	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	326	11	3	3	4.1	CCCCCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL80541	14482	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	326	11	3	3	4.1	CCCCCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	11741184	27951	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	CHEMBL137342	27951	0	None	-	0	Human	6.0	pIC50	=	6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	15666575	5117	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCCc1csc(CCc2ccccc2)c1	10.1021/jm00095a011
	CHEMBL106055	5117	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCCc1csc(CCc2ccccc2)c1	10.1021/jm00095a011
	15666597	109150	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.9	O=C(O)CCCCCCc1csc(Cc2ccccc2)c1	10.1021/jm00095a011
	CHEMBL322290	109150	1	None	-	0	Human	5.0	pIC50	=	5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.9	O=C(O)CCCCCCc1csc(Cc2ccccc2)c1	10.1021/jm00095a011
	135531245	203553	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccnn2C)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	CHEMBL78966	203553	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccnn2C)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	10046878	28221	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137531	28221	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	135503765	203502	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CC(=O)O)c1	10.1021/jm00041a021
	CHEMBL78605	203502	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CC(=O)O)c1	10.1021/jm00041a021
	15666618	9164	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.7	CC(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL110767	9164	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.7	CC(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	10024190	25768	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL135431	25768	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10052488	58742	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.2	CCCc1c(OCCCOc2ccc(-c3coc(C)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169446	58742	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.2	CCCc1c(OCCCOc2ccc(-c3coc(C)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	10069417	164356	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2cccc(Cl)c2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL422282	164356	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2cccc(Cl)c2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	18373405	31482	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL140539	31482	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	9985159	58814	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	555	14	1	8	6.4	CCCc1c(OCCCOc2ccc(-c3csc(OC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169835	58814	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	555	14	1	8	6.4	CCCc1c(OCCCOc2ccc(-c3csc(OC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	44385218	59359	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cccc(C(=O)O)c1	10.1016/S0960-894X(97)00134-0
	CHEMBL172201	59359	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cccc(C(=O)O)c1	10.1016/S0960-894X(97)00134-0
	44385131	128977	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1cccc(C(=O)O)c1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL367291	128977	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1cccc(C(=O)O)c1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00046a017
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00046a017
	18963028	14453	0	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205053	14453	0	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47716	14453	0	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	10343923	27575	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137074	27575	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	135401173	104300	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccccc1CC(=O)O	10.1021/jm00041a021
	CHEMBL310870	104300	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccccc1CC(=O)O	10.1021/jm00041a021
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00070a015
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00070a015
	10053662	59348	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	565	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	CHEMBL172168	59348	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	565	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	44337707	109254	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1cc(-c2ccccc2)sc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL322985	109254	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1cc(-c2ccccc2)sc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	9980059	28147	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(C(F)(F)F)cc2)n1	10.1021/jm00101a008
	CHEMBL137480	28147	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(C(F)(F)F)cc2)n1	10.1021/jm00101a008
	44385159	61022	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)c(C)c1	10.1016/S0960-894X(97)00134-0
	CHEMBL176747	61022	0	None	-	0	Human	5.9	pIC50	=	5.9	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)c(C)c1	10.1016/S0960-894X(97)00134-0
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	10091738	27595	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137089	27595	0	None	-	0	Human	7.9	pIC50	=	7.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsInhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsInhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00064a006
	6444688	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00172a020
	CHEMBL49302	186737	29	None	-	1	Human	7.9	pIC50	=	7.9	Binding	Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophilsInhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00172a020
	6435820	164464	6	None	-	1	Human	6.9	pIC50	=	6.9	Binding	Inhibitory concentration against LTB4 receptors in human PMNsInhibitory concentration against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	CHEMBL422598	164464	6	None	-	1	Human	6.9	pIC50	=	6.9	Binding	Inhibitory concentration against LTB4 receptors in human PMNsInhibitory concentration against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	204058	162907	5	None	-	1	Human	7.8	pIC50	=	7.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL419948	162907	5	None	-	1	Human	7.8	pIC50	=	7.8	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	9805394	57279	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL166699	57279	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	10385899	27200	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL136805	27200	0	None	-	0	Human	6.9	pIC50	=	6.9	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	393	9	1	4	5.6	COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	10474602	25774	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL135434	25774	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10069416	28173	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL137497	28173	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10341135	29175	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL138380	29175	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44381856	167991	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	1	7	6.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC2C(=O)O	10.1021/jm00006a002
	CHEMBL435665	167991	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	1	7	6.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC2C(=O)O	10.1021/jm00006a002
	9930128	60097	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.1	COc1ccc(C(=O)O)cc1NC(=O)/C=C(\C)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL175073	60097	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.1	COc1ccc(C(=O)O)cc1NC(=O)/C=C(\C)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	11726048	27391	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136953	27391	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10071290	27890	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137303	27890	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	429	9	1	3	6.5	O=C(O)CCCCCOc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10318241	28136	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137472	28136	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10250881	24866	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	408	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL134698	24866	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	408	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10390056	116049	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	472	10	2	4	5.9	O=C(O)CCCCCOc1cc(-c2ccc(NC(=O)C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL336303	116049	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	472	10	2	4	5.9	O=C(O)CCCCCOc1cc(-c2ccc(NC(=O)C(F)(F)F)cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10451768	27688	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137168	27688	0	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	15666613	9153	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCc2ccccc2)c(CCCCCCC(=O)O)s1	10.1021/jm00095a011
	CHEMBL110708	9153	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCc2ccccc2)c(CCCCCCC(=O)O)s1	10.1021/jm00095a011
	44385199	59331	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	375	7	2	3	4.6	COc1ccc(C(=O)O)cc1NC(=O)CCc1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL172091	59331	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	375	7	2	3	4.6	COc1ccc(C(=O)O)cc1NC(=O)CCc1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	20704716	184142	0	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	CHEMBL485054	184142	0	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	11549986	155666	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1542	48	11	26	1.8	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)c1ccc(N/N=C/c2ccccc2)nc1	10.1021/jm050383h
	CHEMBL406432	155666	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1542	48	11	26	1.8	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)c1ccc(N/N=C/c2ccccc2)nc1	10.1021/jm050383h
	44386172	165237	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	397	6	2	5	4.2	COc1ccc(-c2nn[nH]n2)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL424779	165237	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	397	6	2	5	4.2	COc1ccc(-c2nn[nH]n2)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	11726048	27391	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136953	27391	1	None	-	0	Human	6.8	pIC50	=	6.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	360	9	1	3	4.8	NC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	44359651	118678	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL343124	118678	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	6441619	205055	13	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Inhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assayInhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	CHEMBL90214	205055	13	None	-	1	Human	4.8	pIC50	=	4.8	Binding	Inhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assayInhibitory concentration LTB4 with [3H]LTD4 in LTD4 receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	15718079	100967	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3c(C(=O)O)cccc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	CHEMBL297501	100967	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3c(C(=O)O)cccc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	10430674	118833	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL344230	118833	0	None	-	0	Human	7.8	pIC50	=	7.8	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	10315808	26743	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	9	1	3	5.3	O=C(O)CCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL136433	26743	0	None	-	0	Human	5.8	pIC50	=	5.8	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	9	1	3	5.3	O=C(O)CCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	10248148	115495	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL335525	115495	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	15839736	14471	0	None	-	1	Human	6.7	pIC50	=	6.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL1205143	14471	0	None	-	1	Human	6.7	pIC50	=	6.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL58534	14471	0	None	-	1	Human	6.7	pIC50	=	6.7	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	44385258	60049	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	7	2	3	5.1	CCOc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL174638	60049	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	7	2	3	5.1	CCOc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	6444688	186737	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	CHEMBL49302	186737	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	10022413	27451	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136991	27451	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10343923	27575	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137074	27575	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	453	9	1	5	6.1	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	10341242	27942	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	CHEMBL137336	27942	0	None	-	0	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	6444688	186737	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	CHEMBL49302	186737	29	None	-	1	Human	8.7	pIC50	=	8.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	9805394	57279	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL166699	57279	0	None	-	0	Human	8.6	pIC50	=	8.6	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	485	13	2	6	4.3	CCCc1c(OCCCOc2ccc(C(N)=O)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	18963032	100623	0	None	-	1	Human	8.5	pIC50	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL294987	100623	0	None	-	1	Human	8.5	pIC50	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	114999	3482	15	None	-	1	Human	7.7	pIC50	=	7.7	Binding	Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingCompound was tested for inhibitory activity against LTB4 (leukotriene) binding	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm960088k
	6156	3482	15	None	-	1	Human	7.7	pIC50	=	7.7	Binding	Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingCompound was tested for inhibitory activity against LTB4 (leukotriene) binding	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm960088k
	CHEMBL14823	3482	15	None	-	1	Human	7.7	pIC50	=	7.7	Binding	Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingCompound was tested for inhibitory activity against LTB4 (leukotriene) binding	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm960088k
	10477988	27932	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137330	27932	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44357546	116253	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	CHEMBL337563	116253	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	178581	139724	1	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree CInhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C	ChEMBL	413	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnn[nH]1	10.1021/jm050383h
	CHEMBL380555	139724	1	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree CInhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C	ChEMBL	413	9	1	5	5.5	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnn[nH]1	10.1021/jm050383h
	15666615	9087	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	372	11	1	2	6.4	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)(C)C(=O)O)s1	10.1021/jm00095a011
	CHEMBL110243	9087	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Capability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability of compound to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	372	11	1	2	6.4	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)(C)C(=O)O)s1	10.1021/jm00095a011
	10386030	118766	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	395	9	1	3	6.1	O=C(O)CCCCCOc1cc(-c2ccccc2Cl)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL343710	118766	0	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	395	9	1	3	6.1	O=C(O)CCCCCOc1cc(-c2ccccc2Cl)cc(-c2ccccc2)n1	10.1021/jm00101a008
	44379592	56863	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	387	10	3	4	4.7	[N-]=[N+]=Nc1ccc(CCCCC(O)/C=C/C2CCCC(O)(CC(=O)O)C2)cc1	10.1016/s0960-894x(00)00103-7
	CHEMBL164721	56863	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	387	10	3	4	4.7	[N-]=[N+]=Nc1ccc(CCCCC(O)/C=C/C2CCCC(O)(CC(=O)O)C2)cc1	10.1016/s0960-894x(00)00103-7
	44379573	57794	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL167465	57794	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	10021622	28388	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	10	1	3	5.7	O=C(O)CCCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137676	28388	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	363	10	1	3	5.7	O=C(O)CCCCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	10430946	114993	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccc(Cl)cc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL335142	114993	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccc(Cl)cc2n1)C(=O)O	10.1021/jm00101a007
	15718082	186590	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cccc(C(=O)O)c3oc2c1CCC(=O)O	10.1021/jm00064a006
	CHEMBL49209	186590	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cccc(C(=O)O)c3oc2c1CCC(=O)O	10.1021/jm00064a006
	195214	183257	14	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	454	16	2	4	6.2	CCCCCCCCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1021/jm00064a006
	CHEMBL48068	183257	14	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	454	16	2	4	6.2	CCCCCCCCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1021/jm00064a006
	443292	4956	11	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	299	3	2	5	3.6	CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1	10.1021/jm00045a011
	CHEMBL105139	4956	11	None	-	0	Human	6.7	pIC50	=	6.7	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	299	3	2	5	3.6	CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1	10.1021/jm00045a011
	9934500	165049	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL424290	165049	0	None	-	0	Human	5.7	pIC50	=	5.7	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	10319829	25913	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135612	25913	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10387303	27393	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136955	27393	0	None	-	0	Human	7.7	pIC50	=	7.7	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	15839732	45431	0	None	-	1	Human	7.6	pIC50	=	7.6	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15299	45431	0	None	-	1	Human	7.6	pIC50	=	7.6	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	44404447	168193	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	2973	97	22	50	0.7	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)c1ccc(N/N=C/c2ccccc2)nc1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL437275	168193	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	2973	97	22	50	0.7	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)c1ccc(N/N=C/c2ccccc2)nc1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	10007005	120280	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.1	C=CCc1c(OCCCOc2ccc3c(c2CCC)OC(C(=O)O)CC3)ccc(-c2cscn2)c1OC	10.1021/jm00006a002
	CHEMBL355503	120280	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	523	13	1	7	6.1	C=CCc1c(OCCCOc2ccc3c(c2CCC)OC(C(=O)O)CC3)ccc(-c2cscn2)c1OC	10.1021/jm00006a002
	10474602	25774	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL135434	25774	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	10	1	3	5.8	O=C(O)CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9999718	24862	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL134697	24862	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10046386	28363	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2cc(Cl)ccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL137654	28363	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	397	8	1	3	6.2	CC(C)(CCCCOc1cc(-c2ccccc2)c2cc(Cl)ccc2n1)C(=O)O	10.1021/jm00101a007
	10482767	168047	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	553	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	CHEMBL436047	168047	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	553	15	1	7	7.1	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(CCC(=O)O)CC2	10.1021/jm00006a002
	44384958	59566	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccc(C)cc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL172974	59566	0	None	-	0	Human	6.6	pIC50	=	6.6	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccc(C)cc2)cc1	10.1016/S0960-894X(97)00134-0
	135507252	203885	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	438	13	3	5	5.0	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL81503	203885	0	None	-	0	Human	7.6	pIC50	=	7.6	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	438	13	3	5	5.0	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	10483151	59259	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	571	14	1	8	7.1	CCCc1c(OCCCOc2ccc(-c3csc(SC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL171780	59259	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	571	14	1	8	7.1	CCCc1c(OCCCOc2ccc(-c3csc(SC)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	18373300	118820	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL344176	118820	0	None	-	0	Human	5.6	pIC50	=	5.6	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	10406292	28184	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137504	28184	0	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	204055	206570	5	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL99099	206570	5	None	-	0	Human	8.5	pIC50	=	8.5	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	6444688	186737	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	CHEMBL49302	186737	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a008
	6444688	186737	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	CHEMBL49302	186737	29	None	-	1	Human	8.5	pIC50	=	8.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00101a007
	10023244	25957	1	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135671	25957	1	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	9999755	26367	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL136094	26367	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2F)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10091738	27595	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137089	27595	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	389	9	1	3	6.0	Cc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10475503	27799	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137247	27799	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10406292	28184	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137504	28184	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	361	9	1	3	5.4	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9976757	28289	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137581	28289	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10362331	28512	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	CHEMBL137801	28512	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	10451768	27688	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137168	27688	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	369	8	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1	10.1021/jm00101a007
	10387480	27803	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	CHEMBL137248	27803	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	10407251	118576	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL342688	118576	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)cc1	10.1021/jm00101a007
	10024190	25768	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL135431	25768	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	10	1	4	5.5	CN(C)c1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10362331	28512	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	CHEMBL137801	28512	4	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	379	9	1	3	5.6	O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(F)cc2)n1	10.1021/jm00101a008
	44403823	161396	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL415548	161396	0	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	129065	107059	22	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	377	4	3	6	3.2	Cc1c(O)c(C)c2sc(NCc3ccc(S(N)(=O)=O)cc3)nc2c1C	10.1021/jm00045a011
	CHEMBL318809	107059	22	None	-	0	Human	7.5	pIC50	=	7.5	Binding	Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsTested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils	ChEMBL	377	4	3	6	3.2	Cc1c(O)c(C)c2sc(NCc3ccc(S(N)(=O)=O)cc3)nc2c1C	10.1021/jm00045a011
	18963030	14454	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205054	14454	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47725	14454	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	15666588	96428	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCCCC(C)C(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	CHEMBL265563	96428	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCCCC(C)C(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	15666614	110815	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)C(=O)O)s1	10.1021/jm00095a011
	CHEMBL326650	110815	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	Cc1cc(CCCc2ccccc2)c(CCCCCC(C)C(=O)O)s1	10.1021/jm00095a011
	9841175	14480	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205297	14480	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL77513	14480	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	114999	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assayCompound was evaluated in a human neutrophil leukotriene B4 receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00126a001
	6156	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assayCompound was evaluated in a human neutrophil leukotriene B4 receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00126a001
	CHEMBL14823	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assayCompound was evaluated in a human neutrophil leukotriene B4 receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00126a001
	44213761	120221	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	346	9	3	3	3.7	O=C(O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL354872	120221	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	346	9	3	3	3.7	O=C(O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	114999	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human neutrophils	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00100a034
	6156	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human neutrophils	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00100a034
	CHEMBL14823	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Concentration inhibiting the binding of [3H]LTB4 to human neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human neutrophils	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00100a034
	10387303	27393	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136955	27393	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	418	11	2	4	6.3	CC(C)Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10427789	27732	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137201	27732	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10455429	28749	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	431	8	1	3	6.6	CC(C)(CCCCOc1cc(-c2ccc(C(F)(F)F)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL138018	28749	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	431	8	1	3	6.6	CC(C)(CCCCOc1cc(-c2ccc(C(F)(F)F)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10430678	167845	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1cccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)c1	10.1021/jm00101a007
	CHEMBL434810	167845	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	393	9	1	4	5.6	COc1cccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc3ccccc23)c1	10.1021/jm00101a007
	10314767	28330	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	333	7	1	3	4.7	O=C(O)CCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137633	28330	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	333	7	1	3	4.7	O=C(O)CCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10407131	161407	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	Cc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	CHEMBL415687	161407	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	Cc1ccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)cc1	10.1021/jm00101a008
	114999	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00070a015
	6156	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00070a015
	CHEMBL14823	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00070a015
	15666630	8005	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	362	11	1	3	6.0	Cc1cc(CCCc2ccccc2)c(SCCCCCC(=O)O)s1	10.1021/jm00095a011
	CHEMBL109129	8005	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	362	11	1	3	6.0	Cc1cc(CCCc2ccccc2)c(SCCCCCC(=O)O)s1	10.1021/jm00095a011
	15666582	110197	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	360	12	1	3	5.5	COc1ccc(CCCc2sccc2CCCCCCC(=O)O)cc1	10.1021/jm00095a011
	CHEMBL326000	110197	0	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	360	12	1	3	5.5	COc1ccc(CCCc2sccc2CCCCCCC(=O)O)cc1	10.1021/jm00095a011
	44317392	203536	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	511	13	2	7	4.8	CCCc1c(OCCCOc2cc(O)c(C(=O)/C=C/N(C)C)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	CHEMBL78859	203536	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	511	13	2	7	4.8	CCCc1c(OCCCOc2cc(O)c(C(=O)/C=C/N(C)C)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	2487	2336	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	5280492	2336	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	CHEMBL65061	2336	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	DB12961	2336	32	None	31	2	Human	7.5	pIC50	=	7.5	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80853-2
	114999	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	6156	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	CHEMBL14823	3482	15	None	-	1	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	10053028	58697	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	540	13	2	8	5.9	CCCc1c(OCCCOc2ccc(-c3csc(N)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169120	58697	0	None	-	0	Human	6.5	pIC50	=	6.5	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	540	13	2	8	5.9	CCCc1c(OCCCOc2ccc(-c3csc(N)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	6441619	205055	13	None	-	1	Human	5.5	pIC50	=	5.5	Binding	Inhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assayInhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	CHEMBL90214	205055	13	None	-	1	Human	5.5	pIC50	=	5.5	Binding	Inhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assayInhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assay	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	18963062	14613	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1206683	14613	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL295799	14613	0	None	-	1	Human	7.5	pIC50	=	7.5	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	15666601	6069	1	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.7	O=C(O)CCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL108094	6069	1	None	-	0	Human	5.5	pIC50	=	5.5	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	302	9	1	2	4.7	O=C(O)CCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	15839733	45380	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15295	45380	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	44296838	193172	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Compound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itselfCompound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itself	ChEMBL	334	14	2	2	5.4	CCCCC/C=C\C[C@@H](C)/C=C/C=C/C=C/[C@@H](O)CCCC(=O)O	10.1016/S0960-894X(01)80795-2
	CHEMBL53967	193172	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Compound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itselfCompound was tested for its antagonist activity in a LTB4 human neutrophil receptor binding assay using the natural ligand itself	ChEMBL	334	14	2	2	5.4	CCCCC/C=C\C[C@@H](C)/C=C/C=C/C=C/[C@@H](O)CCCC(=O)O	10.1016/S0960-894X(01)80795-2
	15839729	205161	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm960088k
	CHEMBL15559	205161	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm960088k
	CHEMBL90788	205161	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm960088k
	15839729	205161	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15559	205161	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL90788	205161	1	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	9955657	204929	11	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	455	13	2	5	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C(=N)N)cc1	10.1021/jm960088k
	CHEMBL89326	204929	11	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	455	13	2	5	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C(=N)N)cc1	10.1021/jm960088k
	9893718	204775	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	CHEMBL292768	204775	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	CHEMBL88337	204775	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	9893718	204775	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL292768	204775	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL88337	204775	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	10046878	28221	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137531	28221	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	405	10	1	4	5.7	COc1ccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	9976757	28289	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137581	28289	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	1	3	5.7	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10430674	118833	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL344230	118833	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	393	9	1	3	5.8	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2F)n1)C(=O)O	10.1021/jm00101a008
	9912012	161655	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL416277	161655	0	None	-	1	Human	8.4	pIC50	=	8.4	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	10364772	27949	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137341	27949	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	204055	206570	5	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL99099	206570	5	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	135543808	203872	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	480	11	3	6	4.9	CCCc1c(OCCCOc2cc(O)c(-c3cc[nH]n3)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	CHEMBL81401	203872	0	None	-	0	Human	8.4	pIC50	=	8.4	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	480	11	3	6	4.9	CCCc1c(OCCCOc2cc(O)c(-c3cc[nH]n3)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00041a021
	132379	111240	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm9506985
	CHEMBL328712	111240	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm9506985
	132379	111240	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Concentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophils	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111240	13	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Concentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophilsConcentration inhibiting the binding of [3H]LTB4 to human whole cell neutrophils	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	10292143	116097	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL336665	116097	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL48667	116097	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	10292143	116097	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL336665	116097	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL48667	116097	1	None	-	1	Human	8.3	pIC50	=	8.3	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	10090758	58691	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	373	9	2	3	3.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL169055	58691	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	373	9	2	3	3.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccccc2)C1	10.1016/s0960-894x(00)00103-7
	10047140	27400	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL136960	27400	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10001576	28169	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137494	28169	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	9999718	24862	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL134697	24862	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	378	8	2	4	5.1	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	14946858	28948	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL138174	28948	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	375	9	0	4	5.5	COC(=O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10068808	27502	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	387	8	1	5	4.9	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	CHEMBL137030	27502	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	387	8	1	5	4.9	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	18373405	31482	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL140539	31482	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	525	7	1	3	7.3	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12	10.1016/j.bmcl.2003.08.070
	18373357	116293	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL337790	116293	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	44359651	118678	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL343124	118678	0	None	-	0	Human	6.4	pIC50	=	6.4	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	481	7	1	3	7.2	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Cl)cc12	10.1016/j.bmcl.2003.08.070
	10021742	9365	4	None	-	1	Human	5.4	pIC50	=	5.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9365	4	None	-	1	Human	5.4	pIC50	=	5.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	10248148	115495	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL335525	115495	0	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	363	8	1	3	5.6	CC(C)(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	44270188	51111	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15817	51111	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	18963059	14455	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205055	14455	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47726	14455	0	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	204055	206570	5	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL99099	206570	5	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	537	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	60490	205530	104	None	-	0	Human	6.4	pIC50	=	6.4	Binding	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	ChEMBL	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	10.1021/jm950725r
	CHEMBL93	205530	104	None	-	0	Human	6.4	pIC50	=	6.4	Binding	In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophilsIn vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils	ChEMBL	236	2	2	3	2.7	CC(c1cc2ccccc2s1)N(O)C(N)=O	10.1021/jm950725r
	114999	3482	15	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	6156	3482	15	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	CHEMBL14823	3482	15	None	-	1	Human	7.4	pIC50	=	7.4	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)Binding affinity towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA)	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00006a002
	9934323	99789	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	CHEMBL288758	99789	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00064a006
	10170399	14653	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL1207275	14653	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL384950	14653	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [111In]-(17)] as radioligand in pH 7.2 buffer, for 1 hr at 37 degree C; (n=2)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	10415107	14729	0	None	-	0	Human	4.4	pIC50	=	4.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsDisplacement of [3H]LTB4 from LTB4 receptor in human neutrophils	ChEMBL	504	4	2	7	4.1	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)OCc3c(OS(=O)(=O)O)ccc(OS(=O)(=O)O)c3C[C@H]21	10.1021/np50120a024
	CHEMBL1207951	14729	0	None	-	0	Human	4.4	pIC50	=	4.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsDisplacement of [3H]LTB4 from LTB4 receptor in human neutrophils	ChEMBL	504	4	2	7	4.1	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)OCc3c(OS(=O)(=O)O)ccc(OS(=O)(=O)O)c3C[C@H]21	10.1021/np50120a024
	CHEMBL462734	14729	0	None	-	0	Human	4.4	pIC50	=	4.4	Binding	Displacement of [3H]LTB4 from LTB4 receptor in human neutrophilsDisplacement of [3H]LTB4 from LTB4 receptor in human neutrophils	ChEMBL	504	4	2	7	4.1	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)OCc3c(OS(=O)(=O)O)ccc(OS(=O)(=O)O)c3C[C@H]21	10.1021/np50120a024
	10022413	27451	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136991	27451	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	376	9	2	4	5.0	Nc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10170399	14653	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL1207275	14653	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	CHEMBL384950	14653	0	None	-	0	Human	7.4	pIC50	=	7.4	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer upon incubation for 1 hr at 37 degree C; (n=4)	ChEMBL	1018	33	4	16	7.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)c1ccc(N/N=C/c2ccccc2S(=O)(=O)O)nc1	10.1021/jm050383h
	15666610	7823	1	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL109016	7823	1	None	-	0	Human	5.4	pIC50	=	5.4	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	316	10	1	2	5.1	O=C(O)CCCCCc1sccc1CCCc1ccccc1	10.1021/jm00095a011
	44385160	61023	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2C)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL176748	61023	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	5.0	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2C)cc1	10.1016/S0960-894X(97)00134-0
	19427041	14474	0	None	-	1	Human	7.3	pIC50	=	7.3	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL1205171	14474	0	None	-	1	Human	7.3	pIC50	=	7.3	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL60881	14474	0	None	-	1	Human	7.3	pIC50	=	7.3	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	10023244	25957	1	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135671	25957	1	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	389	9	1	3	6.1	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10047140	27400	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL136960	27400	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2cccc(Cl)c2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10475503	27799	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137247	27799	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	9	2	4	5.3	CC(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10318241	28136	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL137472	28136	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	390	10	2	4	5.5	CNc1ccc(-c2cc(OCCCCCC(=O)O)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10001576	28169	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137494	28169	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccc(Cl)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10436331	120033	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	2	7	5.0	CCCc1c(OCCCOc2ccc(-c3c[nH]nn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL354553	120033	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	509	13	2	7	5.0	CCCc1c(OCCCOc2ccc(-c3c[nH]nn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	15237280	57795	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	511	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167474	57795	0	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	511	13	2	6	4.6	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	3368	1150	18	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibitionTested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibition	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	9867257	1150	18	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibitionTested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibition	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	CHEMBL51770	1150	18	None	-	0	Human	8.3	pIC50	=	8.3	Binding	Tested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibitionTested for binding activity against [3H]LTB4 to whole human neutrophil with halh maximal inhibition	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm00046a001
	135543742	203677	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CCC(=O)O)c1	10.1021/jm00041a021
	CHEMBL79991	203677	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1cccc(CCC(=O)O)c1	10.1021/jm00041a021
	44348541	16641	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	323	7	1	2	3.0	CN(CCc1ccccc1)C(=O)Cc1cccc(/C=C/C(=O)O)c1	10.1021/jm9506985
	CHEMBL124717	16641	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	323	7	1	2	3.0	CN(CCc1ccccc1)C(=O)Cc1cccc(/C=C/C(=O)O)c1	10.1021/jm9506985
	44357534	26535	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	CHEMBL136243	26535	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	385	9	0	6	4.7	c1ccc(-c2cc(OCCCCCn3cnnn3)nc(-c3ccccc3)c2)cc1	10.1021/jm00101a008
	10341135	29175	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL138380	29175	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	403	10	1	3	6.5	CC(C)(CCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10427789	27732	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137201	27732	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	347	8	1	3	5.0	O=C(O)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10363959	28301	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137594	28301	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	10387480	27803	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	CHEMBL137248	27803	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes	ChEMBL	421	8	1	5	5.6	CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1	10.1021/jm00101a007
	11725988	27778	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	359	8	1	5	4.2	c1ccc(-c2cc(OCCCCCc3nnn[nH]3)nc3ccccc23)cc1	10.1021/jm00101a007
	CHEMBL137234	27778	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	359	8	1	5	4.2	c1ccc(-c2cc(OCCCCCc3nnn[nH]3)nc3ccccc23)cc1	10.1021/jm00101a007
	10340408	118060	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1cccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)c1	10.1021/jm00101a008
	CHEMBL341565	118060	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	391	10	1	4	5.4	COc1cccc(-c2cc(-c3ccccc3)cc(OCCCCCC(=O)O)n2)c1	10.1021/jm00101a008
	18373300	118820	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL344176	118820	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	492	8	1	5	6.5	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12	10.1016/j.bmcl.2003.08.070
	15666581	5572	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.2	O=C(O)CCCCCCc1csc(CCCc2ccc(O)cc2)c1	10.1021/jm00095a011
	CHEMBL107781	5572	0	None	-	0	Human	5.3	pIC50	=	5.3	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.2	O=C(O)CCCCCCc1csc(CCCc2ccc(O)cc2)c1	10.1021/jm00095a011
	10391552	119816	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3c[nH]cn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL352863	119816	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3c[nH]cn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	135507183	203929	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2ccn[nH]2)c(O)cc1OCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL81817	203929	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	396	10	3	5	3.8	CCc1cc(-c2ccn[nH]2)c(O)cc1OCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	44403823	161396	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL415548	161396	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	3125	109	25	54	-4.2	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	135507225	103744	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	424	12	3	5	4.6	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL309883	103744	0	None	-	0	Human	7.3	pIC50	=	7.3	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	424	12	3	5	4.6	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(CC(=O)O)cc1	10.1021/jm00041a021
	10247237	28275	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	8	1	3	5.2	CC(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL137570	28275	0	None	-	0	Human	6.3	pIC50	=	6.3	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	349	8	1	3	5.2	CC(CCCCOc1cc(-c2ccccc2)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	10032156	58708	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	647	16	1	8	8.6	CCCc1c(OCCCOc2ccc(-c3csc(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169246	58708	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	647	16	1	8	8.6	CCCc1c(OCCCOc2ccc(-c3csc(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	9906324	14450	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205046	14450	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL46820	14450	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	9906324	14450	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL1205046	14450	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL46820	14450	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	9865985	28461	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137759	28461	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	9	1	5	5.2	O=C(O)CCCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9978895	118471	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL342416	118471	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor of human polymorphonuclear leukocytes	ChEMBL	409	9	1	3	6.3	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2Cl)n1)C(=O)O	10.1021/jm00101a008
	6450158	186591	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49210	186591	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	6450158	186591	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49210	186591	14	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	135516891	156974	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	384	10	3	6	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	CHEMBL407983	156974	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	384	10	3	6	3.8	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	18963040	14699	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL1207571	14699	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL416259	14699	0	None	-	1	Human	8.2	pIC50	=	8.2	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	10364772	27949	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137341	27949	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	419	9	1	5	5.4	CC(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10092630	27613	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137104	27613	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	132425	6787	4	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	CC(C)(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL108415	6787	4	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	358	11	1	2	6.1	CC(C)(CCCCCc1sccc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	11799000	16986	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Compound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMNCompound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMN	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	CHEMBL125611	16986	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Compound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMNCompound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMN	ChEMBL	482	9	1	4	5.1	CN(O)C(=O)c1cc(CC(=O)N(C)CCc2ccccc2)c2cccc(OCc3ccccc3)c2c1	10.1021/jm950699x
	10319829	25913	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL135612	25913	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	417	11	1	3	6.9	CC(C)(CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10363959	28301	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137594	28301	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	406	10	1	5	5.3	O=C(O)CCCCCOc1cc(-c2ccc([N+](=O)[O-])cc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	15666631	8003	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.0	O=C(O)CCCCCC(O)c1sccc1CCCc1ccccc1	10.1021/jm00095a011
	CHEMBL109128	8003	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	346	11	2	3	5.0	O=C(O)CCCCCC(O)c1sccc1CCCc1ccccc1	10.1021/jm00095a011
	44379572	119794	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	540	10	2	4	5.3	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])c(I)c2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL352717	119794	0	None	-	0	Human	5.2	pIC50	=	5.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	540	10	2	4	5.3	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])c(I)c2)C1	10.1016/s0960-894x(00)00103-7
	9849151	58787	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3cc[nH]n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169683	58787	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	508	13	2	6	5.6	CCCc1c(OCCCOc2ccc(-c3cc[nH]n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	15839731	49186	0	None	-	1	Human	7.2	pIC50	=	7.2	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15648	49186	0	None	-	1	Human	7.2	pIC50	=	7.2	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	10339300	129703	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL367943	129703	0	None	-	0	Human	7.2	pIC50	=	7.2	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	373	6	2	3	4.7	COc1ccc(C(=O)O)cc1NC(=O)/C=C/c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	10341242	27942	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	CHEMBL137336	27942	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	405	10	1	4	5.7	COc1cccc(-c2cc(OCCCCC(C)C(=O)O)nc(-c3ccccc3)c2)c1	10.1021/jm00101a008
	10477988	27932	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137330	27932	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	433	9	1	5	5.8	CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	44357546	116253	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	CHEMBL337563	116253	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	399	9	0	6	5.2	CC(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)n1cnnn1	10.1021/jm00101a008
	9911868	17850	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determinedInhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determined	ChEMBL	455	11	1	7	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCOc1ccc2c(N)noc2c1	10.1016/S0960-894X(97)00025-5
	CHEMBL126463	17850	0	None	-	0	Human	8.2	pIC50	=	8.2	Binding	Inhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determinedInhibitory concentration of compound against Leukotriene B4 receptor binding to human neutrophils was determined	ChEMBL	455	11	1	7	4.9	COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCOc1ccc2c(N)noc2c1	10.1016/S0960-894X(97)00025-5
	15666586	108080	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCCCCC(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	CHEMBL320258	108080	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	344	11	1	2	5.8	Cc1cc(CCCCCCC(=O)O)c(CCCc2ccccc2)s1	10.1021/jm00095a011
	44379573	57794	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	CHEMBL167465	57794	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Compound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranesCompound was tested for inhibition against binding of radioligand [3H]LTB4 to Leukotriene B4 receptor in human neutrophil membranes	ChEMBL	414	10	2	4	4.7	CN(C)C(=O)CC1(O)CCCC(/C=C/C(O)CCCCc2ccc(N=[N+]=[N-])cc2)C1	10.1016/s0960-894x(00)00103-7
	10019853	28324	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	335	8	1	3	4.9	O=C(O)CCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	CHEMBL137625	28324	0	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	335	8	1	3	4.9	O=C(O)CCCCCOc1cc(-c2ccccc2)c2ccccc2n1	10.1021/jm00101a007
	10337448	27897	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	342	8	0	3	5.9	N#CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	CHEMBL137307	27897	1	None	-	0	Human	6.2	pIC50	=	6.2	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.	ChEMBL	342	8	0	3	5.9	N#CCCCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm00101a008
	9841175	14480	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205297	14480	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL77513	14480	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	44315539	14628	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	312	10	3	3	3.7	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CCCC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1206776	14628	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	312	10	3	3	3.7	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CCCC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL305933	14628	0	None	-	0	Human	4.2	pIC50	=	4.2	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	312	10	3	3	3.7	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CCCC(=O)O)C1	10.1016/0960-894X(96)00424-6
	135430350	167491	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1ccc(CCC(=O)O)cc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	CHEMBL432363	167491	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1ccc(CCC(=O)O)cc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	10021742	9365	4	None	-	1	Human	6.1	pIC50	=	6.1	Binding	Binding affinity to LTB4 receptor in human U937 cells by whole cell assayBinding affinity to LTB4 receptor in human U937 cells by whole cell assay	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9365	4	None	-	1	Human	6.1	pIC50	=	6.1	Binding	Binding affinity to LTB4 receptor in human U937 cells by whole cell assayBinding affinity to LTB4 receptor in human U937 cells by whole cell assay	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	10349070	130366	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	630	16	2	7	7.9	CCCc1c(OCCCOc2ccc(-c3c[nH]c(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL368540	130366	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.Binding affinity towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.	ChEMBL	630	16	2	7	7.9	CCCc1c(OCCCOc2ccc(-c3c[nH]c(SCc4ccccc4)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	10481412	59473	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3ccno3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL172628	59473	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	509	13	1	7	5.9	CCCc1c(OCCCOc2ccc(-c3ccno3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	44384957	165685	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	389	7	2	4	4.3	COc1ccc(C(=O)O)cc1NC(=O)CC(=O)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL426773	165685	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	389	7	2	4	4.3	COc1ccc(C(=O)O)cc1NC(=O)CC(=O)c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	44403368	160780	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	2750	92	21	47	-1.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](N)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	CHEMBL412510	160780	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)Inhibitory concentration against human leukotriene B4 receptor using competing agent [3H]-LTB4 as radioligand in pH 7.2 buffer, for 1 h at 37 degree C; (n=2)	ChEMBL	2750	92	21	47	-1.6	CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)[C@H](CS(=O)(=O)O)NC(=O)CC[C@H](N)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)NCCCOCCOCCOCCCNC(=O)CCCCn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1	10.1021/jm050383h
	3368	1150	18	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm960088k
	9867257	1150	18	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm960088k
	CHEMBL51770	1150	18	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingCompound was tested for inhibitory activity against Leukotriene B4 receptor binding	ChEMBL	428	5	2	3	5.5	OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1	10.1021/jm960088k
	9958915	57815	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	CHEMBL167669	57815	0	None	-	0	Human	8.1	pIC50	=	8.1	Binding	Inhibitory activity against leukotriene B4 receptorInhibitory activity against leukotriene B4 receptor	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@@H](CCC(=O)O)CC2	10.1016/S0960-894X(01)80853-2
	10741106	117299	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	426	9	0	4	4.7	CN(CCc1ccccc1)C(=O)Cn1cc(C=O)c2cc(OCc3ccccc3)ccc21	10.1021/jm950699x
	CHEMBL340180	117299	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneCompound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membrane	ChEMBL	426	9	0	4	4.7	CN(CCc1ccccc1)C(=O)Cn1cc(C=O)c2cc(OCc3ccccc3)ccc21	10.1021/jm950699x
	15666623	167233	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	CHEMBL430520	167233	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Capability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 MCapability to inhibit the binding of [3H]LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M	ChEMBL	434	12	1	2	7.8	CC(C)(CCCCCc1sc(-c2ccccc2)cc1CCCc1ccccc1)C(=O)O	10.1021/jm00095a011
	9841175	14480	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205297	14480	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	CHEMBL77513	14480	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	346	9	3	3	3.7	O=C(O)C[C@]1(O)CCC[C@H](/C=C/C(O)CCCCc2ccccc2)C1	10.1016/0960-894X(96)00424-6
	11740566	118942	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	381	8	1	3	5.7	CC(C)(CCCCOc1cc(-c2ccccc2F)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	CHEMBL345047	118942	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	381	8	1	3	5.7	CC(C)(CCCCOc1cc(-c2ccccc2F)c2ccccc2n1)C(=O)O	10.1021/jm00101a007
	9934500	165049	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL424290	165049	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayInhibitory concentration against LTB4 receptor determined in human neutrophils PMN assay	ChEMBL	472	7	1	4	6.4	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C#N)cc12	10.1016/j.bmcl.2003.08.070
	44315583	14479	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	284	8	3	3	2.9	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL1205289	14479	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	284	8	3	3	2.9	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	CHEMBL76530	14479	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligandCompound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand	ChEMBL	284	8	3	3	2.9	CCCCCC(O)/C=C/[C@H]1CCC[C@@](O)(CC(=O)O)C1	10.1016/0960-894X(96)00424-6
	9976891	27956	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1c(OCCCCC(C)(C)C(=O)O)nc2ccccc2c1-c1ccccc1	10.1021/jm00101a007
	CHEMBL137346	27956	0	None	-	0	Human	5.1	pIC50	=	5.1	Binding	Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranesInhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes	ChEMBL	377	8	1	3	5.9	Cc1c(OCCCCC(C)(C)C(=O)O)nc2ccccc2c1-c1ccccc1	10.1021/jm00101a007
	135543741	203884	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.7	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(C(=O)O)cc1	10.1021/jm00041a021
	CHEMBL81489	203884	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.7	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCOc1ccc(C(=O)O)cc1	10.1021/jm00041a021
	44385920	61053	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1ccccc1C(=O)O	10.1016/S0960-894X(97)00134-0
	CHEMBL176974	61053	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	343	5	2	2	4.7	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1ccccc1C(=O)O	10.1016/S0960-894X(97)00134-0
	15718085	100875	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3ccc(C(=O)O)cc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	CHEMBL296869	100875	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsInhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils	ChEMBL	468	14	2	5	6.2	CCCCCCCCCCOc1cc2oc3ccc(C(=O)O)cc3c(=O)c2cc1CCC(=O)O	10.1021/jm00064a006
	135507273	203584	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1c(CCC(=O)O)cccc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	CHEMBL79233	203584	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	452	13	3	5	5.2	CCCc1c(CCC(=O)O)cccc1OCCCOc1cc(O)c(-c2cc[nH]n2)cc1CC	10.1021/jm00041a021
	122023	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsIn vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	4534	191305	89	None	-	0	Human	7.1	pIC50	=	7.1	Binding	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	ChEMBL	302	5	4	4	3.6	CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1	10.1021/jm00085a019
	CHEMBL52	191305	89	None	-	0	Human	7.1	pIC50	=	7.1	Binding	The compound was tested for its inhibitory activity against LTB4 in human PMNThe compound was tested for its inhibitory activity against LTB4 in human PMN	ChEMBL	302	5	4	4	3.6	CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1	10.1021/jm00085a019
	122023	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	122023	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition against LTB4 receptor in human neutrophilInhibition against LTB4 receptor in human neutrophil	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	122023	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm00041a021
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm00041a021
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1021/jm00041a021
	135500104	163221	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	CHEMBL420576	163221	0	None	-	0	Human	7.1	pIC50	=	7.1	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	410	11	3	5	4.2	CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccc(CCC(=O)O)cc1	10.1021/jm00041a021
	10347709	58793	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	557	13	2	8	6.6	CCCc1c(OCCCOc2ccc(-c3csc(S)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL169722	58793	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	557	13	2	8	6.6	CCCc1c(OCCCOc2ccc(-c3csc(S)n3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	135457469	105160	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccn(C)n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	CHEMBL312483	105160	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]Leukotriene B4 binding to human PMNInhibition of [3H]Leukotriene B4 binding to human PMN	ChEMBL	398	10	2	7	3.8	CCc1cc(-c2ccn(C)n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1	10.1021/jm00041a021
	10092630	27613	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	CHEMBL137104	27613	0	None	-	0	Human	8.0	pIC50	=	8.0	Binding	Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.	ChEMBL	404	9	2	4	5.7	CC(C)(CCCCOc1cc(-c2ccc(N)cc2)cc(-c2ccccc2)n1)C(=O)O	10.1021/jm00101a008
	10737187	15344	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	359	8	0	2	4.5	CN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1	10.1021/jm9506985
	CHEMBL121748	15344	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsCompound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells	ChEMBL	359	8	0	2	4.5	CN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1	10.1021/jm9506985
	18373357	116293	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	CHEMBL337790	116293	0	None	-	0	Human	6.1	pIC50	=	6.1	Binding	Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayInhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assay	ChEMBL	461	7	1	3	6.9	COc1cc(C(=O)O)ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(C)cc12	10.1016/j.bmcl.2003.08.070
	44386171	61045	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	377	5	2	2	5.4	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cc(C(=O)O)ccc1Cl	10.1016/S0960-894X(97)00134-0
	CHEMBL176903	61045	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	377	5	2	2	5.4	O=C(/C=C/c1ccc(-c2ccccc2)cc1)Nc1cc(C(=O)O)ccc1Cl	10.1016/S0960-894X(97)00134-0
	10052575	58646	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	525	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	CHEMBL168944	58646	0	None	-	0	Human	7.0	pIC50	=	7.0	Binding	Binding affinity for Leukotriene B4 (LTB4) receptorBinding affinity for Leukotriene B4 (LTB4) receptor	ChEMBL	525	13	1	7	6.4	CCCc1c(OCCCOc2ccc(-c3cscn3)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2	10.1021/jm00006a002
	44385966	60105	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	4.8	COc1ccc(C(=O)O)cc1NC(=O)[C@H]1C[C@@H]1c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	CHEMBL175128	60105	0	None	-	0	Human	6.0	pIC50	=	6.0	Binding	In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophilsIn vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]LTB4 from isolated neutrophils	ChEMBL	387	6	2	3	4.8	COc1ccc(C(=O)O)cc1NC(=O)[C@H]1C[C@@H]1c1ccc(-c2ccccc2)cc1	10.1016/S0960-894X(97)00134-0
	192617	100284	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292782	100284	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	192617	100284	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292782	100284	16	None	-	1	Human	10.4	pKi	=	10.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	19600933	201112	0	None	-	1	Human	10.1	pKi	=	10.1	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL62265	201112	0	None	-	1	Human	10.1	pKi	=	10.1	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	10745838	117559	0	None	-	1	Human	10.0	pKi	=	10.0	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL340460	117559	0	None	-	1	Human	10.0	pKi	=	10.0	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	2487	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	5280492	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL65061	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	DB12961	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80999-9
	2487	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	5280492	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL65061	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	DB12961	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	2487	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	5280492	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	CHEMBL65061	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	DB12961	2336	32	None	31	2	Human	9.9	pKi	=	9.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	132379	111240	13	None	-	1	Human	9.9	pKi	=	9.9	Binding	Affinity for guinea pig PMN LTB-4 receptors.Affinity for guinea pig PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111240	13	None	-	1	Human	9.9	pKi	=	9.9	Binding	Affinity for guinea pig PMN LTB-4 receptors.Affinity for guinea pig PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	10120811	96005	0	None	-	1	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL262231	96005	0	None	-	1	Human	9.9	pKi	=	9.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	192617	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00046a017
	CHEMBL292782	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00046a017
	192617	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	CHEMBL292782	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm960088k
	192617	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292782	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	192617	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292782	100284	16	None	-	1	Human	9.3	pKi	=	9.3	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	600	12	3	7	6.6	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	10745838	117559	0	None	-	1	Human	9.2	pKi	=	9.2	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL340460	117559	0	None	-	1	Human	9.2	pKi	=	9.2	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	582	12	3	7	6.4	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	6441619	205055	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	CHEMBL90214	205055	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960248s
	6441619	205055	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorCompound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptor	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960088k
	CHEMBL90214	205055	13	None	-	1	Human	9.1	pKi	=	9.1	Binding	Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorCompound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptor	ChEMBL	459	9	1	4	6.4	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1	10.1021/jm960088k
	9850643	205952	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	554	19	2	6	6.4	CCCc1c(OCCCCCCc2cccc(OCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm00046a017
	CHEMBL95453	205952	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	554	19	2	6	6.4	CCCc1c(OCCCCCCc2cccc(OCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm00046a017
	15658147	9493	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a013
	CHEMBL112487	9493	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a013
	CHEMBL112520	9493	0	None	-	1	Human	9.0	pKi	=	9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a013
	9850974	204544	0	None	-	1	Human	9.0	pKi	=	9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	568	20	2	6	6.8	CCCc1c(OCCCCCCc2cccc(OCCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm960088k
	CHEMBL86900	204544	0	None	-	1	Human	9.0	pKi	=	9	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	568	20	2	6	6.8	CCCc1c(OCCCCCCc2cccc(OCCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O	10.1021/jm960088k
	15658147	9493	0	None	-	1	Human	9.0	pKi	=	9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL112487	9493	0	None	-	1	Human	9.0	pKi	=	9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL112520	9493	0	None	-	1	Human	9.0	pKi	=	9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	411	13	3	4	5.2	CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	10120811	96005	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL262231	96005	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(Oc2ccc(C(=O)O)cc2)c1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	19600933	201112	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL62265	201112	0	None	-	1	Human	9.0	pKi	=	9.0	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	534	13	3	5	5.8	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc(C#CCCC(=O)O)cc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	9893718	204775	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL292768	204775	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL88337	204775	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	10529082	18630	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	489	10	1	5	6.4	COc1ccc(CCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL127913	18630	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	489	10	1	5	6.4	COc1ccc(CCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	9893718	204775	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292768	204775	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL88337	204775	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	204058	162907	5	None	-	1	Human	8.9	pKi	=	8.9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm00046a017
	CHEMBL419948	162907	5	None	-	1	Human	8.9	pKi	=	8.9	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	539	15	2	6	5.4	CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1O[C@H](CCC(=O)O)CC2	10.1021/jm00046a017
	10529241	18326	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	493	9	1	4	7.1	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(Cl)cc1	10.1021/jm960248s
	CHEMBL127376	18326	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	493	9	1	4	7.1	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(Cl)cc1	10.1021/jm960248s
	10648186	17983	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	473	10	1	4	6.8	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCCc1ccccc1	10.1021/jm960248s
	CHEMBL126976	17983	0	None	-	1	Human	8.9	pKi	=	8.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	473	10	1	4	6.8	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCCc1ccccc1	10.1021/jm960248s
	11798848	16355	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	477	9	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(F)cc1	10.1021/jm960248s
	CHEMBL123722	16355	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	477	9	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccc(F)cc1	10.1021/jm960248s
	9958441	116334	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	517	12	1	5	7.2	COc1ccc(CCCCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL337995	116334	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	517	12	1	5	7.2	COc1ccc(CCCCOc2ccc(CSc3c(Cl)cccc3Cl)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	2487	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	5280492	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL65061	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	DB12961	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1016/S0960-894X(01)80105-0
	2487	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	5280492	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	CHEMBL65061	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	DB12961	2336	32	None	31	2	Human	8.7	pKi	=	8.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/jm00076a030
	18963032	100623	0	None	-	1	Human	8.7	pKi	=	8.7	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL294987	100623	0	None	-	1	Human	8.7	pKi	=	8.7	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	444	11	2	6	4.5	CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	44340787	14412	0	None	-	1	Human	8.0	pKi	=	8	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	435	12	3	4	6.0	CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1204561	14412	0	None	-	1	Human	8.0	pKi	=	8	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	435	12	3	4	6.0	CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL326397	14412	0	None	-	1	Human	8.0	pKi	=	8	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	435	12	3	4	6.0	CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15839729	205161	1	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15559	205161	1	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL90788	205161	1	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	456	11	2	6	4.7	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	10046307	14627	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1206771	14627	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL305560	14627	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	15658110	14405	0	None	-	1	Human	7.0	pKi	=	7	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCCC(O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL113528	14405	0	None	-	1	Human	7.0	pKi	=	7	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCCC(O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1204495	14405	0	None	-	1	Human	7.0	pKi	=	7	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCCC(O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15658157	14406	0	None	-	1	Human	6.0	pKi	=	6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	449	12	3	5	4.9	CCCCOc1cccc(C(O)CCc2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL114454	14406	0	None	-	1	Human	6.0	pKi	=	6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	449	12	3	5	4.9	CCCCOc1cccc(C(O)CCc2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL1204496	14406	0	None	-	1	Human	6.0	pKi	=	6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	449	12	3	5	4.9	CCCCOc1cccc(C(O)CCc2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	10037501	184141	3	None	-	1	Human	4.0	pKi	=	4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	245	1	1	5	0.5	CN1C(=O)/C(=C/c2ccc3c(c2)OCO3)N=C1N	10.1021/np50100a005
	CHEMBL485053	184141	3	None	-	1	Human	4.0	pKi	=	4	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	245	1	1	5	0.5	CN1C(=O)/C(=C/c2ccc3c(c2)OCO3)N=C1N	10.1021/np50100a005
	18963059	14455	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205055	14455	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47726	14455	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	402	11	2	6	4.7	CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	14977959	9396	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	506	15	2	5	6.0	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112018	9396	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	506	15	2	5	6.0	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	18963030	14454	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205054	14454	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47725	14454	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	442	12	2	6	5.1	CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	21765776	163139	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccccc3C(=O)O)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL420488	163139	0	None	-	1	Human	7.0	pKi	=	7.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccccc3C(=O)O)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	14977907	9459	0	None	-	1	Human	6.0	pKi	=	6.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	483	18	2	5	6.8	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL112310	9459	0	None	-	1	Human	6.0	pKi	=	6.0	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	483	18	2	5	6.8	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	14977965	110861	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	524	15	2	5	6.2	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL326909	110861	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	524	15	2	5	6.2	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	11798329	18319	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	463	8	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCc1ccc(F)cc1	10.1021/jm960248s
	CHEMBL127341	18319	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	463	8	1	4	6.5	O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCc1ccc(F)cc1	10.1021/jm960248s
	11800543	19194	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129272	19194	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	122023	50523	56	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL15766	50523	56	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL45460	50523	56	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	23257866	9375	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL111908	9375	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	10021742	9365	4	None	-	1	Human	5.9	pKi	=	5.9	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	CHEMBL111825	9365	4	None	-	1	Human	5.9	pKi	=	5.9	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/np50100a005
	14977963	9552	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	574	15	2	5	7.1	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112737	9552	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	574	15	2	5	7.1	Nc1cccc([S+]([O-])Cc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	9829619	100285	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292783	100285	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranesLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in guinea pig lung membranes	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	9977200	29163	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL138370	29163	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL60617	29163	0	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	10292143	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL336665	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL48667	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	10292143	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL336665	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL48667	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	10292143	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL336665	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	CHEMBL48667	116097	1	None	-	1	Human	7.9	pKi	=	7.9	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80454-0
	18963040	14699	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1207571	14699	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL416259	14699	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	15658122	9672	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	453	12	2	4	6.0	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL113514	9672	0	None	-	1	Human	6.9	pKi	=	6.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	453	12	2	4	6.0	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15658098	168750	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	383	13	2	3	6.3	CCCCCCCCC(O)c1ccc2ccc(/C=C/CCCC(=O)O)nc2c1	10.1021/jm00074a012
	CHEMBL441647	168750	0	None	-	1	Human	5.9	pKi	=	5.9	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	383	13	2	3	6.3	CCCCCCCCC(O)c1ccc2ccc(/C=C/CCCC(=O)O)nc2c1	10.1021/jm00074a012
	14977952	108550	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	676	19	2	7	7.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL321261	108550	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	676	19	2	7	7.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977946	110091	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	531	18	2	6	6.2	CCCCCCCCCCCCOc1ccc(CS(=O)(=O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL325423	110091	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	531	18	2	6	6.2	CCCCCCCCCCCCOc1ccc(CS(=O)(=O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	44270188	51111	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	CHEMBL15817	51111	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	484	13	1	6	5.4	CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80304-2
	9984593	9546	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	533	17	2	5	7.3	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCCCCCc1ccccc1	10.1021/jm00046a017
	CHEMBL112707	9546	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	533	17	2	5	7.3	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCCCCCc1ccccc1	10.1021/jm00046a017
	15839733	45380	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15295	45380	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	458	14	2	6	5.2	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(CC)C(=O)O	10.1016/S0960-894X(00)80304-2
	14977913	9171	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	5.7	COc1ccc(CCCCCCCCOc2ccc(COc3cccc(C(=O)O)c3)[n+]([O-])c2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL110797	9171	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	5.7	COc1ccc(CCCCCCCCOc2ccc(COc3cccc(C(=O)O)c3)[n+]([O-])c2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977924	110458	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL326192	110458	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10812265	57839	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2cccc(OC)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167923	57839	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2cccc(OC)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10475982	161275	0	None	-15	2	Human	4.8	pKi	=	4.8	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL414462	161275	0	None	-15	2	Human	4.8	pKi	=	4.8	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	21765774	9609	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL113146	9609	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	14977898	9995	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	519	15	3	6	5.3	COc1ccc(CCCCCCOc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL115437	9995	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	519	15	3	6	5.3	COc1ccc(CCCCCCOc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977924	110458	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL326192	110458	0	None	-	1	Human	6.8	pKi	=	6.8	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	17	2	6	6.2	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	10405361	14476	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205188	14476	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL62051	14476	0	None	-	1	Human	7.8	pKi	=	7.8	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	15839732	45431	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15299	45431	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	444	13	2	6	4.8	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OC(C)C(=O)O	10.1016/S0960-894X(00)80304-2
	44382468	58779	0	None	-	1	Human	5.7	pKi	=	5.7	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL169639	58779	0	None	-	1	Human	5.7	pKi	=	5.7	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	44341107	9369	0	None	-	1	Human	4.7	pKi	=	4.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	277	4	1	3	3.2	Cn1c(N)nc(Cc2ccccc2)c1Cc1ccccc1	10.1021/jm00074a014
	CHEMBL111872	9369	0	None	-	1	Human	4.7	pKi	=	4.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	277	4	1	3	3.2	Cn1c(N)nc(Cc2ccccc2)c1Cc1ccccc1	10.1021/jm00074a014
	23257889	9411	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	535	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112088	9411	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	535	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	132379	111240	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Affinity for human PMN LTB-4 receptors.Affinity for human PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	CHEMBL328712	111240	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Affinity for human PMN LTB-4 receptors.Affinity for human PMN LTB-4 receptors.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00100a034
	132379	111240	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00070a015
	CHEMBL328712	111240	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00070a015
	132379	111240	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00046a017
	CHEMBL328712	111240	13	None	-	1	Human	8.7	pKi	=	8.7	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	453	9	1	3	5.4	CN(CCc1ccccc1)C(=O)Cc1cc(C(=O)O)cc2c(OCc3ccccc3)cccc12	10.1021/jm00046a017
	10694814	16393	0	None	-	1	Human	8.6	pKi	=	8.6	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	449	12	1	5	5.9	COc1ccc(CCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL123862	16393	0	None	-	1	Human	8.6	pKi	=	8.6	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	449	12	1	5	5.9	COc1ccc(CCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	2487	2336	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	5280492	2336	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	CHEMBL65061	2336	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	DB12961	2336	32	None	31	2	Human	8.5	pKi	=	8.5	Binding	Displacement of [3H]LTB4 from LTB4RDisplacement of [3H]LTB4 from LTB4R	ChEMBL	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	10.1021/np50094a001
	10182429	57831	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	428	10	2	5	5.7	CCc1cc(-c2ccc(Cl)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167850	57831	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	428	10	2	5	5.7	CCc1cc(-c2ccc(Cl)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	11800543	19194	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129272	19194	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	538	11	2	6	6.7	CCc1cc(-c2ccccc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	18963040	14699	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1207571	14699	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL416259	14699	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	18963040	14699	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL1207571	14699	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	CHEMBL416259	14699	0	None	-	1	Human	7.7	pKi	=	7.7	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	14	2	6	5.0	CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/S0960-894X(00)80453-9
	114999	3482	15	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00074a014
	6156	3482	15	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00074a014
	CHEMBL14823	3482	15	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1021/jm00074a014
	44341141	9343	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	667	18	1	7	6.9	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(CS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL111723	9343	0	None	-	1	Human	6.7	pKi	=	6.7	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	667	18	1	7	6.9	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(CS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	23257891	9613	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	551	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL113167	9613	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	551	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(OC)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10325873	9428	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL112169	9428	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	579	18	2	6	6.3	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	44382378	58561	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL168854	58561	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	44341318	9458	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	349	8	2	4	3.5	Cn1c(N)nc(Cc2ccc(CCCCO)cc2)c1Cc1ccccc1	10.1021/jm00074a014
	CHEMBL112309	9458	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	349	8	2	4	3.5	Cn1c(N)nc(Cc2ccc(CCCCO)cc2)c1Cc1ccccc1	10.1021/jm00074a014
	23257882	109926	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	564	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL324478	109926	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	564	17	1	6	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10745069	29882	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	542	13	2	4	7.9	CCCc1c(Cc2ccccc2C(=O)O)cccc1OCCCOc1cc(O)c(-c2ccc(F)cc2)cc1CC	10.1021/jm00022a006
	CHEMBL138954	29882	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	542	13	2	4	7.9	CCCc1c(Cc2ccccc2C(=O)O)cccc1OCCCOc1cc(O)c(-c2ccc(F)cc2)cc1CC	10.1021/jm00022a006
	177941	1558	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	2948	1558	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	CHEMBL329123	1558	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	DB12850	1558	40	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	10.1021/jm960088k
	9906324	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against Guinea pig membrane LTB4 ReceptorBinding affinity against Guinea pig membrane LTB4 Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL1205046	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against Guinea pig membrane LTB4 ReceptorBinding affinity against Guinea pig membrane LTB4 Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL46820	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against Guinea pig membrane LTB4 ReceptorBinding affinity against Guinea pig membrane LTB4 Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	9906324	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205046	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL46820	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	9906324	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL1205046	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	CHEMBL46820	14450	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80454-0
	14977920	9388	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccc(C(=O)O)cc2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL111969	9388	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccc(C(=O)O)cc2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	44341073	10033	0	None	-	1	Human	4.6	pKi	=	4.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	307	5	1	4	3.2	COc1cccc(Cc2nc(N)n(C)c2Cc2ccccc2)c1	10.1021/jm00074a014
	CHEMBL115679	10033	0	None	-	1	Human	4.6	pKi	=	4.6	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	307	5	1	4	3.2	COc1cccc(Cc2nc(N)n(C)c2Cc2ccccc2)c1	10.1021/jm00074a014
	10324028	9933	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	509	15	2	6	5.6	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	CHEMBL115040	9933	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	509	15	2	6	5.6	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	44302963	14472	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205145	14472	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL58794	14472	0	None	-	1	Human	7.6	pKi	=	7.6	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	9826485	105883	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00070a015
	CHEMBL313923	105883	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00070a015
	114999	3482	15	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assayIn vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	6156	3482	15	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assayIn vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	CHEMBL14823	3482	15	None	-	1	Human	6.6	pKi	=	6.6	Binding	In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assayIn vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay	ChEMBL	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	10.1016/0960-894X(95)00135-G
	15658099	162781	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	385	14	2	3	6.2	CCCCCCCCC(O)c1ccc2ccc(CCCCCC(=O)O)nc2c1	10.1021/jm00074a012
	CHEMBL419036	162781	0	None	-	1	Human	5.6	pKi	=	5.6	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	385	14	2	3	6.2	CCCCCCCCC(O)c1ccc2ccc(CCCCCC(=O)O)nc2c1	10.1021/jm00074a012
	9826485	105883	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL313923	105883	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	469	16	3	5	5.7	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/C(=O)O	10.1021/jm00074a013
	14977927	10159	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	652	18	2	7	7.7	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL116101	10159	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	652	18	2	7	7.7	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)C(F)(F)F)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	15658155	14403	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	447	11	3	5	5.0	CCCCOc1cccc(C(O)/C=C/c2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL113288	14403	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	447	11	3	5	5.0	CCCCOc1cccc(C(O)/C=C/c2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	CHEMBL1204493	14403	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	447	11	3	5	5.0	CCCCOc1cccc(C(O)/C=C/c2cccc(CC(O)c3cccc(C(=O)O)c3)n2)c1	10.1021/jm00074a012
	10179915	57800	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167520	57800	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	44302965	197276	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	551	14	1	7	6.5	CCCc1c(OCCCOc2ccc(-c3cscn3)c(COC)c2CC2CC2)ccc2c1O[C@@H](C(=O)O)CC2	10.1021/jm990504b
	CHEMBL58495	197276	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	551	14	1	7	6.5	CCCc1c(OCCCOc2ccc(-c3cscn3)c(COC)c2CC2CC2)ccc2c1O[C@@H](C(=O)O)CC2	10.1021/jm990504b
	192624	167926	2	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	394	10	2	5	5.1	CCc1cc(-c2ccccc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL435273	167926	2	None	-	1	Human	8.5	pKi	=	8.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	394	10	2	5	5.1	CCc1cc(-c2ccccc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	9912012	161655	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	CHEMBL416277	161655	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	In vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayIn vitro binding affinity using [3H]LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	458	12	2	6	4.9	CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2c1OC(C(=O)O)CC2	10.1016/S0960-894X(00)80454-0
	9906324	14450	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity against human neutrophil ReceptorBinding affinity against human neutrophil Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL1205046	14450	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity against human neutrophil ReceptorBinding affinity against human neutrophil Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL46820	14450	0	None	-	1	Human	8.5	pKi	=	8.5	Binding	Binding affinity against human neutrophil ReceptorBinding affinity against human neutrophil Receptor	ChEMBL	348	10	2	6	3.4	CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	6157	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm960088k
	6438358	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm960088k
	CHEMBL422420	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingCompound was tested for inhibitory activity against human neutrophil LTB4 receptor binding	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm960088k
	44302966	96052	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	484	13	2	6	4.9	CCCc1c(OCCCOc2ccc3c(c2CCC)O[C@@H](C(=O)O)CC3)ccc(C(C)=O)c1CO	10.1021/jm990504b
	CHEMBL262530	96052	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity to leukotriene B4 receptorBinding affinity to leukotriene B4 receptor	ChEMBL	484	13	2	6	4.9	CCCc1c(OCCCOc2ccc3c(c2CCC)O[C@@H](C(=O)O)CC3)ccc(C(C)=O)c1CO	10.1021/jm990504b
	10554820	30065	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	556	13	2	5	7.5	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1C(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139115	30065	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	556	13	2	5	7.5	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1C(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	44302963	14472	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205145	14472	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL58794	14472	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	402	14	2	5	5.5	CCCCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	9845585	57848	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccc(C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL168011	57848	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccc(C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	44382275	59425	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL172457	59425	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	C[C@@H](Oc1ccc2c(c1)OC[C@@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	44382384	59230	0	None	-	1	Human	5.5	pKi	=	5.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL171666	59230	0	None	-	1	Human	5.5	pKi	=	5.5	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1ccccn1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	14977911	9508	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	499	18	2	5	6.0	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)[n+]([O-])c1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL112544	9508	0	None	-	1	Human	6.5	pKi	=	6.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	499	18	2	5	6.0	CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)[n+]([O-])c1/C=C/C(=O)O	10.1021/jm00074a013
	14977931	9565	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	520	16	2	6	7.0	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112808	9565	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	520	16	2	6	7.0	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10021742	9365	4	None	-	1	Human	5.5	pKi	=	5.5	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/jm00074a014
	CHEMBL111825	9365	4	None	-	1	Human	5.5	pKi	=	5.5	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	365	4	1	7	2.6	Cn1c(N)nc(Cc2ccc3c(c2)OCO3)c1Cc1ccc2c(c1)OCO2	10.1021/jm00074a014
	14977957	9429	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	490	15	2	5	7.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112176	9429	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	490	15	2	5	7.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccccc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	14977933	9797	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	552	16	2	7	5.7	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL114290	9797	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	552	16	2	7	5.7	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10507666	30702	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	592	13	2	6	7.1	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1S(=O)(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139799	30702	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	592	13	2	6	7.1	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1S(=O)(=O)c1ccccc1C(=O)O	10.1021/jm00022a006
	9807782	19230	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129463	19230	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	6444688	186737	29	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00074a014
	CHEMBL49302	186737	29	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1021/jm00074a014
	23257894	9564	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	521	16	1	5	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112804	9564	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	521	16	1	5	6.5	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10342316	57843	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2ccc(OC)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167972	57843	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	424	11	2	6	5.1	CCc1cc(-c2ccc(OC)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10363485	58794	0	None	-29	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL169743	58794	0	None	-29	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	9800998	98909	1	None	-32	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL282524	98909	1	None	-32	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2cc(OCc3ccc4ccccc4n3)ccc2OC[C@@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	9829619	100285	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	CHEMBL292783	100285	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	LTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophilLTB4 receptor antagonist activity was determined by inhibition of specific binding of [3H]LTB4 in human neutrophil	ChEMBL	574	14	3	6	7.1	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cc(Oc2ccc(C(=O)O)cc2)ccc1CCC(=O)O	10.1016/S0960-894X(01)80105-0
	44382463	58912	0	None	-9	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assayIn vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assay	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	CHEMBL170226	58912	0	None	-9	2	Human	4.4	pKi	=	4.4	Binding	In vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assayIn vitro inhibitory activity was evaluated against leukotriene B4 (LTB4) in guinea pig binding assay	ChEMBL	398	5	1	5	4.5	O[C@@H]1c2ccc(OCc3ccc4ccccc4n3)cc2OC[C@H]1Cc1cccnc1	10.1016/0960-894X(95)00135-G
	6157	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00070a015
	6438358	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00070a015
	CHEMBL422420	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandBinding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligand	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00070a015
	6157	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00046a017
	6438358	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00046a017
	CHEMBL422420	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	10.1021/jm00046a017
	9807782	19230	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL129463	19230	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor	ChEMBL	556	11	2	6	6.9	CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccc2c(=O)c3ccccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	9893718	204775	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL292768	204775	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	CHEMBL88337	204775	0	None	-	1	Human	8.4	pKi	=	8.4	Binding	Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorTested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptor	ChEMBL	548	12	3	8	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1CCC(=O)O	10.1021/jm00076a030
	3083459	119882	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2cccc(F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL353378	119882	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	412	10	2	5	5.2	CCc1cc(-c2cccc(F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	6439436	9463	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112338	9463	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	6439436	9463	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL112338	9463	2	None	-	1	Human	8.3	pKi	=	8.3	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	536	16	2	6	6.0	COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])c3cccc(N)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	10292143	116097	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL336665	116097	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL48667	116097	1	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	362	11	2	6	3.8	CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	10050724	10029	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	477	13	2	5	5.7	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCc1ccccc1	10.1021/jm00046a017
	CHEMBL115658	10029	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	477	13	2	5	5.7	O=C(O)/C=C/c1nc(CSCc2cccc(C(=O)O)c2)ccc1OCCCCc1ccccc1	10.1021/jm00046a017
	15839731	49186	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	CHEMBL15648	49186	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	430	13	2	6	4.4	CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1OCC(=O)O	10.1016/S0960-894X(00)80304-2
	9872540	30227	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	560	13	2	5	8.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Sc1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139254	30227	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	560	13	2	5	8.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Sc1ccccc1C(=O)O	10.1021/jm00022a006
	14977894	110118	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	471	17	3	5	5.6	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1CCC(=O)O	10.1021/jm00074a013
	CHEMBL325615	110118	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	471	17	3	5	5.6	CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1CCC(=O)O	10.1021/jm00074a013
	14977961	9419	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	558	15	2	5	8.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	CHEMBL112135	9419	0	None	-	1	Human	7.4	pKi	=	7.4	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	558	15	2	5	8.0	Nc1cccc(SCc2ccc(OCCCCCCCCc3ccc(C(F)(F)F)cc3)c(/C=C/C(=O)O)n2)c1	10.1021/jm00074a013
	6450158	186591	14	None	-	1	Human	7.4	pKi	=	7.4	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49210	186591	14	None	-	1	Human	7.4	pKi	=	7.4	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	14977916	110837	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccccc2C(=O)O)nc1/C=C/C(=O)O	10.1021/jm00074a013
	CHEMBL326779	110837	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	515	18	2	5	6.5	CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccccc2C(=O)O)nc1/C=C/C(=O)O	10.1021/jm00074a013
	10405361	14476	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1205188	14476	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL62051	14476	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	346	10	2	5	3.9	CCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	9977200	29163	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL138370	29163	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL60617	29163	0	None	-	1	Human	8.3	pKi	=	8.3	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	360	11	2	5	4.3	CCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	21765772	110121	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL325637	110121	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3ccc(C(=O)O)cc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	10793277	30869	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	576	13	2	5	7.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1[S+]([O-])c1ccccc1C(=O)O	10.1021/jm00022a006
	CHEMBL139969	30869	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligandBinding affinity towards LTB4 receptor guinea pig spleen cells using [3H]LTB4 as radioligand	ChEMBL	576	13	2	5	7.4	CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1[S+]([O-])c1ccccc1C(=O)O	10.1021/jm00022a006
	6450158	186591	14	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition constant against binding of [3H]LTB4 to human neutrophilsInhibition constant against binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	CHEMBL49210	186591	14	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition constant against binding of [3H]LTB4 to human neutrophilsInhibition constant against binding of [3H]LTB4 to human neutrophils	ChEMBL	516	12	2	6	5.9	COc1ccc(/C=C/CCCCOc2ccc3c(=O)c4cc(C(=O)O)ccc4oc3c2CCC(=O)O)cc1	10.1021/jm00064a006
	15658112	62844	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCC[C@@H](O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1788228	62844	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCC[C@@H](O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL1789864	62844	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	419	12	2	3	6.5	CCCCCCCC[C@@H](O)c1ccc2ccc(CCc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	15658139	14407	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	452	12	2	3	6.6	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL115826	14407	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	452	12	2	3	6.6	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL1204497	14407	0	None	-	1	Human	6.3	pKi	=	6.3	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	452	12	2	3	6.6	CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	18963028	14453	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1205053	14453	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL47716	14453	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	376	11	2	6	4.2	CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	44382276	119810	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	CHEMBL352814	119810	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4)	ChEMBL	412	5	1	5	5.1	CC(Oc1ccc2c(c1)OC[C@H](Cc1cccnc1)[C@@H]2O)c1ccc2ccccc2n1	10.1016/0960-894X(95)00135-G
	10371282	110124	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	595	18	2	7	6.0	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL325643	110124	0	None	-	1	Human	7.3	pKi	=	7.3	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	595	18	2	7	6.0	COc1ccc(CCCCCCCCOc2ccc(CS(=O)(=O)Cc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	20704716	184142	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	CHEMBL485054	184142	0	None	-	1	Human	5.3	pKi	=	5.3	Binding	Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneDisplacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membrane	ChEMBL	488	5	1	9	2.4	CN1C(=N)N(C)/C(=N/c2nc(Cc3ccc4c(c3)OCO4)c(Cc3ccc4c(c3)OCO4)n2C)C1=O	10.1021/np50100a005
	10159791	57702	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccccc2C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167261	57702	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2ccccc2C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10046307	14627	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL1206771	14627	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	CHEMBL305560	14627	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against human neutrophil Receptor.Binding affinity against human neutrophil Receptor.	ChEMBL	374	12	2	5	4.7	CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[nH]n2)cc1O	10.1016/0960-894X(95)00340-Y
	19427041	14474	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL1205171	14474	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	CHEMBL60881	14474	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	534	14	3	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc(C(=O)c2cccc(C(=O)O)c2)cc1CCC(=O)O	10.1016/S0960-894X(01)80999-9
	15658149	14402	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	413	14	3	4	5.1	CCCCCCCCC(O)CCc1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL111811	14402	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	413	14	3	4	5.1	CCCCCCCCC(O)CCc1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	CHEMBL1204492	14402	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	413	14	3	4	5.1	CCCCCCCCC(O)CCc1cccc(CC(O)c2cccc(C(=O)O)c2)n1	10.1021/jm00074a012
	15658119	9718	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	437	12	2	4	7.0	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	CHEMBL113792	9718	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	437	12	2	4	7.0	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)nc2c1	10.1021/jm00074a012
	14977948	9501	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	660	19	2	7	8.2	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112510	9501	0	None	-	1	Human	6.2	pKi	=	6.2	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	660	19	2	7	8.2	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)c4ccccc4)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	9845587	165077	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2cccc(C)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL424361	165077	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	408	10	2	5	5.4	CCc1cc(-c2cccc(C)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	10670634	57371	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	437	11	2	6	5.1	CCc1cc(-c2ccc(N(C)C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL166862	57371	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	437	11	2	6	5.1	CCc1cc(-c2ccc(N(C)C)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	122023	50523	56	None	-	1	Human	7.2	pKi	=	7.2	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL15766	50523	56	None	-	1	Human	7.2	pKi	=	7.2	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	CHEMBL45460	50523	56	None	-	1	Human	7.2	pKi	=	7.2	Binding	Binding affinity against Guinea pig membrane LTB4 Receptor.Binding affinity against Guinea pig membrane LTB4 Receptor.	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/0960-894X(95)00340-Y
	10600128	57803	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	462	10	2	5	6.1	CCc1cc(-c2cccc(C(F)(F)F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	CHEMBL167580	57803	0	None	-	1	Human	7.2	pKi	=	7.2	Binding	Negative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranesNegative logarithm of affinity for leukotriene B4 (LTB4) receptor on guinea pig lung membranes	ChEMBL	462	10	2	5	6.1	CCc1cc(-c2cccc(C(F)(F)F)c2)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80850-7
	6435820	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	CHEMBL422598	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity against LTB4 receptors in human PMNsBinding affinity against LTB4 receptors in human PMNs	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00070a015
	6435820	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL422598	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	6435820	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was tested for binding affinity against Leukotriene B4 receptorCompound was tested for binding affinity against Leukotriene B4 receptor	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960088k
	CHEMBL422598	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Compound was tested for binding affinity against Leukotriene B4 receptorCompound was tested for binding affinity against Leukotriene B4 receptor	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960088k
	6435820	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	CHEMBL422598	164464	6	None	-	1	Human	8.2	pKi	=	8.2	Binding	Inhibition of [3H]LTB4 binding to human neutrophilsInhibition of [3H]LTB4 binding to human neutrophils	ChEMBL	563	18	2	6	7.3	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm960248s
	6444688	186737	29	None	-	1	Human	8.1	pKi	=	8.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	CHEMBL49302	186737	29	None	-	1	Human	8.1	pKi	=	8.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	502	14	2	5	5.9	COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2CCC(=O)O)cc1	10.1016/S0960-894X(01)80999-9
	6852392	17088	4	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	361	14	3	4	4.0	CCCCC/C=C\C[C@H](O)/C=C/c1cccc(C[C@H](O)CCCCO)n1	10.1021/jm00074a012
	CHEMBL1256923	17088	4	None	-	1	Human	6.2	pKi	=	6.2	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	361	14	3	4	4.0	CCCCC/C=C\C[C@H](O)/C=C/c1cccc(C[C@H](O)CCCCO)n1	10.1021/jm00074a012
	14977943	114464	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	592	17	3	7	6.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NC(=O)C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL334267	114464	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	592	17	3	7	6.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NC(=O)C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	14977939	96269	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	505	16	1	5	7.4	COc1ccc(CCCCCCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL264197	96269	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	505	16	1	5	7.4	COc1ccc(CCCCCCCCOc2ccc(CSc3ccccc3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	15839736	14471	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL1205143	14471	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	CHEMBL58534	14471	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	476	9	2	7	5.0	CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1	10.1016/S0960-894X(01)80999-9
	122023	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranesCompound was evaluated for inhibition of binding of [3H]LTB4 to LTB4 receptor in guinea-pig lung membranes	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(01)80999-9
	122023	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity against LTB4 receptor in guinea pig membraneBinding affinity against LTB4 receptor in guinea pig membrane	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80304-2
	122023	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL15766	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL45460	50523	56	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	360	10	2	6	3.6	CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	14977955	9485	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	548	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL112455	9485	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	548	17	1	6	7.5	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(N(C)C)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	10257351	110153	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	19	2	6	7.2	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	CHEMBL325773	110153	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	565	19	2	6	7.2	COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1	10.1021/jm00046a017
	9959228	9980	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL115362	9980	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	9959228	9980	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	CHEMBL115362	9980	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Binding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytesBinding affinity of [3H]LTB4 to receptors on intact human polymorphonuclear leukocytes	ChEMBL	549	17	2	6	7.1	COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00074a013
	18963062	14613	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL1206683	14613	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	CHEMBL295799	14613	0	None	-	1	Human	7.1	pKi	=	7.1	Binding	Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayCompound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assay	ChEMBL	404	13	2	6	4.8	CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1	10.1016/S0960-894X(00)80453-9
	10346127	9586	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	507	14	2	6	5.7	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	CHEMBL112972	9586	0	None	-	1	Human	8.0	pKi	=	8.0	Binding	Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.	ChEMBL	507	14	2	6	5.7	COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1	10.1021/jm00046a017
	15658097	9643	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	401	14	3	4	5.2	CCCCCCCCC(O)c1ccc2ccc(CC(O)CCCC(=O)O)nc2c1	10.1021/jm00074a012
	CHEMBL113351	9643	0	None	-	1	Human	6.1	pKi	=	6.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	401	14	3	4	5.2	CCCCCCCCC(O)c1ccc2ccc(CC(O)CCCC(=O)O)nc2c1	10.1021/jm00074a012
	44341265	10307	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	263	4	2	2	3.2	Nc1nc(Cc2ccccc2)c(Cc2ccccc2)[nH]1	10.1021/jm00074a014
	CHEMBL116278	10307	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]LTB4	ChEMBL	263	4	2	2	3.2	Nc1nc(Cc2ccccc2)c(Cc2ccccc2)[nH]1	10.1021/jm00074a014
	15658135	14404	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	436	12	2	3	7.6	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL113401	14404	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	436	12	2	3	7.6	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	CHEMBL1204494	14404	0	None	-	1	Human	5.1	pKi	=	5.1	Binding	Inhibition of [3H]- LTB4 binding on human whole cellsInhibition of [3H]- LTB4 binding on human whole cells	ChEMBL	436	12	2	3	7.6	CCCCCCCCC(O)c1ccc2ccc(CSc3cccc(C(=O)O)c3)cc2c1	10.1021/jm00074a012
	None	214444	0	3H-LTB4	3	2	Human	9.2	pKi	=	9.2	Binding	NoneNone	PDSP KiDatabase	336	14	3	3	4.2	CCCCCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O	None
	None	214447	0	3H-LTB4	-6	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	318	14	1	2	5.4	CCCCCC=CCC(=O)C=CC=CCC=CCCCC(=O)O	None
	None	214449	0	3H-LTB4	1	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	318	14	1	2	5.4	CCCCCC=CCC=CCC=CC=CC(=O)CCCC(=O)O	None
	None	214450	0	3H-LTB4	-1	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O	None
	None	214453	0	3H-LTB4	1	2	Human	6.0	pKi	=	6	Binding	NoneNone	PDSP KiDatabase	302	12	1	1	5.7	CCCCCC=CCC=CCC=CCC#CCCCC(=O)O	None
	None	214446	0	3H-LTB4	-57	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC(C=CC=CCC=CCC=CCCCC(=O)O)O	None
	None	214450	0	3H-LTB4	-1	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O	None
	None	214451	0	3H-LTB4	-10	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	15	2	2	5.2	C(CCC=CCC=CCC=CCC=CCCCC(=O)O)CCO	None
	None	214452	0	3H-LTB4	-10	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	320	14	2	2	5.2	CCCCCC=CCC=CC=CC(CC=CCCCC(=O)O)O	None
	None	214455	0	3H-LTB4	-4365	4	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	473	7	2	3	7.9	CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)S)O	None
	None	214460	0	3H-LTB4	1	2	Human	5.0	pKi	=	5	Binding	NoneNone	PDSP KiDatabase	332	13	0	3	5.3	CCCCCC=CCC=CC=CC=CC1C(O1)CCCC(=O)OC	None
	132191096	214454	0	3H-LTB4	-1	2	Human	5.8	pKi	=	5.8	Binding	NoneNone	PDSP KiDatabase	352	14	4	4	3.1	CCCCCC(C=CC=CC=CC=CC(C(CCCC(=O)O)O)O)O	None
	None	214456	0	3H-LTB4	4	2	Human	5.7	pKi	=	5.7	Binding	NoneNone	PDSP KiDatabase	625	25	7	8	2.8	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N	None
	None	214458	0	3H-LTB4	2	2	Human	5.6	pKi	=	5.6	Binding	NoneNone	PDSP KiDatabase	439	18	4	5	4.3	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)N	None
	None	214448	0	3H-LTB4	218	2	Human	7.6	pKi	=	7.6	Binding	NoneNone	PDSP KiDatabase	361	14	3	4	4.0	CCCCCC=CCC(C=CC1=NC(=CC=C1)CC(CCCCO)O)O	None
	None	214445	0	3H-LTB4	2	2	Human	8.4	pKi	=	8.4	Binding	NoneNone	PDSP KiDatabase	334	13	3	3	3.9	CCC=CCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O	None
	None	214457	0	3H-LTB4	2	2	Human	5.4	pKi	=	5.4	Binding	NoneNone	PDSP KiDatabase	496	20	5	6	3.4	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)N	None
	None	214459	0	3H-LTB4	1	2	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	568	23	6	7	3.7	CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)NC(=O)CCC(C(=O)O)N	None
	2855	4069	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	3322	4069	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	5717	4069	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	CHEMBL603	4069	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	DB00549	4069	100	3H-LTB4	-147	6	Human	5.2	pKi	=	5.2	Binding	NoneNone	PDSP KiDatabase	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	3325	3841	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	361	14	3	4	4.0	CCCCC/C=C\C[C@H](/C=C/c1cccc(n1)C[C@H](CCCCO)O)O	10513580
	6449854	3841	0	None	-	1	Human	6.4	pKi	=	6.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	361	14	3	4	4.0	CCCCC/C=C\C[C@H](/C=C/c1cccc(n1)C[C@H](CCCCO)O)O	10513580
	3351	2370	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	360	10	2	6	3.6	CCc1c(OCCCCCC(c2nnn[nH]2)(C)C)cc(cc1C(=O)C)O	1659282
	35025716	2370	0	None	-	1	Human	6.6	pKi	=	6.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	360	10	2	6	3.6	CCc1c(OCCCCCC(c2nnn[nH]2)(C)C)cc(cc1C(=O)C)O	1659282
	3405	11	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	320	14	2	2	5.2	CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(=O)O)O	9177352
	5283156	11	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	320	14	2	2	5.2	CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(=O)O)O	9177352
	CHEMBL1435825	11	0	None	-	1	Human	7.5	pKi	=	7.5	Binding	UnclassifiedUnclassified	Guide to Pharmacology	320	14	2	2	5.2	CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(=O)O)O	9177352
	177941	1558	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	2948	1558	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	CHEMBL329123	1558	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	DB12850	1558	40	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	544	13	2	5	8.1	CCCc1c(OCCCOc2cc(O)c(cc2CC)c2ccc(cc2)F)cccc1Oc1ccccc1C(=O)O	9862783
	114999	3482	15	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	6156	3482	15	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	CHEMBL14823	3482	15	None	-	1	Human	7.8	pKi	=	7.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	484	13	1	6	5.4	CCCc1c(OCCCOc2ccc(c(c2CCC)OC)C(=O)C)ccc2c1OC(CC2)C(=O)O	7786309
	3399	42	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	352	15	4	4	3.1	OCCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	9177352
	5280745	42	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	352	15	4	4	3.1	OCCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	9177352
	CHEMBL1593789	42	0	None	-	1	Human	8.1	pKi	=	8.1	Binding	UnclassifiedUnclassified	Guide to Pharmacology	352	15	4	4	3.1	OCCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	9177352
	6155	1153	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	9823886	1153	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	CHEMBL301829	1153	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	DB13053	1153	0	None	-	1	Human	8.2	pKi	=	8.2	Binding	UnclassifiedUnclassified	Guide to Pharmacology	428	4	2	3	5.4	O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1	9618393
	6157	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	6438358	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	CHEMBL422420	2889	16	None	-	1	Human	8.4	pKi	=	8.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	470	17	2	5	5.6	COc1ccc(cc1)/C=C/CCCCOc1cccc(c1CCC(=O)O)OCCCCC(=O)O	1332129
	6154	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	6154	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	9956189	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	11259574
	9956189	627	0	None	-	1	Human	8.8	pKi	=	8.8	Binding	UnclassifiedUnclassified	Guide to Pharmacology	466	9	3	4	6.2	Oc1ccc(cc1)C(c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(=N)N)(C)C	17170051
	2487	2336	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	5280492	2336	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	CHEMBL65061	2336	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	DB12961	2336	32	None	31	2	Human	9.4	pKi	=	9.4	Binding	UnclassifiedUnclassified	Guide to Pharmacology	336	14	3	3	4.2	CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O	None
	2855	4069	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	3322	4069	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	5717	4069	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	CHEMBL603	4069	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None
	DB00549	4069	100	None	-147	6	Human	8.3	pKi	None	8.3	Binding	NoneNone	Drug Central	575	8	2	7	5.7	COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C	None

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