Variation Browser

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Receptor Position GPCRdb Segment Variant Mutation type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
Receptor Position GPCRdb Segment Variant Mutation Type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
ada2a_human 23 N-term A => V missense 8.812e-05 1 11348 0 0.12 0.072
ada2a_human 40 1.39x39 TM1 A => G missense 0.002153 74 34366 1 0.56 0.037
ada2a_human 52 1.51x51 TM1 V => G missense 1.347e-05 1 74218 0 0.01 0.994
ada2a_human 73 2.44x44 TM2 V => G missense 1.781e-05 2 112266 0 0.0 0.994
ada2a_human 85 2.56x551 TM2 L => F missense 1.688e-05 2 118466 0 0.0 0.996
ada2a_human 85 2.56x551 TM2 L => H missense 8.439e-06 1 118496 0 0.0 0.998
ada2a_human 116 3.35x35 TM3 F => L missense 8.314e-06 1 120280 0 0.0 0.969
ada2a_human 126 3.45x45 TM3 A => V missense 1.665e-05 2 120150 0 0.0 0.991
ada2a_human 126 3.45x45 TM3 A => E missense 8.323e-06 1 120150 0 0.0 0.998
ada2a_human 248 ICL3 R => H missense 2.255e-05 1 44348 0 0.03 0.872
ada2a_human 401 ECL3 C => S missense 8.256e-06 1 121122 0 0.0 0.985
ada2a_human 68 2.39x39 TM2 Q => ProfsTer91 frameshift 9.29e-06 1 107638 0 None None
ada2a_human 132 3.51x51 TM3 Y => AlafsTer27 frameshift 8.315e-06 1 120258 0 None None PTM (Phosphorylation)
ada2a_human 234 ICL3 R => HisfsTer241 frameshift 1.751e-05 1 57094 0 None None
ada2a_human 366 6.27x27 TM6 Q => Ter stop gained 6.929e-05 2 28866 0 None None
ada2a_human 384 6.45x45 TM6 V => Ter stop gained 8.513e-06 1 117468 0 None None
ada2a_human 439 8.56x56 H8 K => AlafsTer39 frameshift 8.243e-06 1 121310 0 None None
ada2a_human 444 C-term G => SerfsTer34 frameshift 1.65e-05 2 121248 0 None None


Residue

Diagrams

R A L K ICL1ECL1 Y W Y F ECL1 A I E Y N L K R ICL2ECL2 S I E K K G G G G G P Q P A E P R C E I N D ECL2ICL3 R G P D A V A A P P G G T E R R P N G L G P E R S A G P G G A E A E P L P T Q L N G A P G E P A P A G P R D T D A L D L E E S S S S D H A E R P P G P R R P E R G P R G K G K A R A S Q V K P G D S L P R R G P G A T G I G T P A A G P G E E R V G A A K A S R W ICL3ECL3 C S V P ECL3N-term M G S L Q P D A G N A S W N G T E A P G G G A R A T P Y S N-termC-term R G D R K R I V C-term L Q V T L T L V C L A G L L M L L T V F G N V L V I I A V F T S A P Q N L F L V S L A S A D I L V A T L V I P F S L A N E V M G G K A W C E I Y L A L D V L F C T S S I V H L C A I S L D R Y W S I T Q T P R R I K A I I I T V W V I S A V I S F P P L I Q K W Y V I S S C I G S F F A P C L I M I L V Y V R I Y Q I A K R R T R V P P S R R G R Q N R E K R F T F V L A V V I G V F V V C W F P F F F T Y T L T A V G R T L F K F F F W F G Y C N S S L N P V I Y T I F N H D F K K F R R A I L C
SnakePlot Download: PNG | SVG V N G F V T L L M L L G A L C V L T L T 1 V S L A S A D I L V A L T V I P F S L A N 2 A C L H V I S S T C F L V D L A L Y I E 3 I K A I I I T V W V I S A V I S F P P L 4 Y V L I M I L C P A F F S G I C S S I V Y 5 A V V I G V F V V C W F P F F F T Y T L 6 V P N L S S N C Y G F W F F F K F L T 7
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