- 34355 total mutations.
- 17567 total annotated mutations.
- 192 unique receptors with mutations.
- 78 unique receptors with annotated mutations.
The tree highlights receptors for which ligand interaction data is available from: Orange: annotated literature mutations, Blue: crystal structure complexes and Green: both.
The following receptors have no data and has been exluded for clarity: Class A orphans, Class B2 (Adhesions), Taste 2 and Other GPCRs (not part of any of the classes A-C or F).
The labs of David Gloriam, Anke Schiedel, Chris de Graaf and Hugo Gutiérrez-de-Terán are acknowledged for the annotation of mutation data.