TAS2R4 (ta2r4_mouse)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R4

GENE

Tas2r4 (Tas2r108, Tas2r8)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 4, T2R4, Taste receptor type 2 member 8, T2R8

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
L
W
E
L
Y
V
F
V
F
10
                   
A
A
S
V
F
L
N
F
V
G
20
                   
I
I
A
N
L
F
I
I
V
I
30
                   
I
I
K
T
W
V
N
S
R
R
40
ICL1 TM2      
I
A
S
P
D
R
I
L
F
S
50
                   
L
A
I
T
R
F
L
T
L
G
60
                   
L
F
L
L
N
S
V
Y
I
A
70
    ECL1 TM3  
T
N
T
G
R
S
V
Y
F
S
80
                   
T
F
F
L
L
C
W
K
F
L
90
                   
D
A
N
S
L
W
L
V
T
I
100
                   
L
N
S
L
Y
C
V
K
I
T
110
ICL2            
N
F
Q
H
P
V
F
L
L
L
120
    TM4          
K
R
T
I
S
M
K
T
T
S
130
                   
L
L
L
A
C
L
L
I
S
A
140
                   
L
T
T
L
L
Y
Y
M
L
S
150
  ECL2          
Q
I
S
R
F
P
E
H
I
I
160
                   
G
R
N
D
T
S
F
D
L
S
170
          TM5    
D
G
I
L
T
L
V
A
S
L
180
                   
V
L
N
S
L
L
Q
F
M
L
190
                   
N
V
T
F
A
S
L
L
I
H
200
                   
S
L
R
R
H
I
Q
K
M
Q
210
      ICL3 TM6
R
N
R
T
S
F
W
N
P
Q
220
                   
T
E
A
H
M
G
A
M
R
L
230
                   
M
I
C
F
L
V
L
Y
I
P
240
                   
Y
S
I
A
T
L
L
Y
L
P
250
        ECL3 TM7
S
Y
M
R
K
N
L
R
A
Q
260
                 
A
I
C
M
I
I
T
A
A
Y
270
                   
P
P
G
H
S
V
L
L
I
I
280
  H8              
T
H
H
K
L
K
A
K
A
K
290
             
K
I
F
C
F
Y
K

LINKS

UniProt

DIAGRAMS

ICL1 R I ICL1ECL1 T G R ECL1ICL2 N F Q H P V F L L L K R ICL2ECL2 I S R F P E H I I G R N D T S F D L S D G I L T ECL2ICL3 T S F W ICL3ECL3 K N ECL3N-term M N-term L W E L Y V F V F A A S V F L N F V G I I A N L F I I V I I I K T W V N S R A S P D R I L F S L A I T R F L T L G L F L L N S V Y I A T N S V Y F S T F F L L C W K F L D A N S L W L V T I L N S L Y C V K I T T I S M K T T S L L L A C L L I S A L T T L L Y Y M L S Q L V A S L V L N S L L Q F M L N V T F A S L L I H S L R R H I Q K M Q R N R N P Q T E A H M G A M R L M I C F L V L Y I P Y S I A T L L Y L P S Y M R L R A Q A I C M I I T A A Y P P G H S V L L I I T H H K A K K Y K L K A K I F C F
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N A I I G V F N L F V S A A F V F V Y 1 F S L A I T R F L T L G L F L L N S V Y 2 I T V L W L S N A D L F K W C L L F F T 3 T T S L L L A C L L I S A L T T L L Y Y 4 A F T V N L M F Q L L S N L V L S A V L 5 M I C F L V L Y I P Y S I A T L L Y L P 6 V S H G P P Y A A T I I M C I A Q A R 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available