ADGRG1 (agrg1_mouse)
FAMILY
Class B2 (Adhesion) Adhesion receptors ADGRG ADGRG1
GENE
Adgrg1 (Cyt28, Gpr56)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Adhesion G-protein coupled receptor G1, G-protein coupled receptor 56, Serpentine receptor cyt28, ADGRG1 N-terminal fragment, ADGRG1 NT, GPR56 N-terminal fragment, GPR56 NT, GPR56(N), GPR56 extracellular subunit, GPR56 subunit alpha, ADGRG1 C-terminal fragment, ADGRG1-CT, GPR56 C-terminal fragment, GPR56 CT, GPR56(C), GPR56 seven-transmembrane subunit, GPR56 7TM, GPR56 subunit beta
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
A
|
V
|
Q
|
V
|
L
|
R
|
Q
|
M
|
V
|
10 |
Y
|
F
|
L
|
L
|
S
|
L
|
F
|
S
|
L
|
V
|
20 |
Q
|
G
|
A
|
H
|
S
|
G
|
S
|
P
|
R
|
E
|
30 |
D
|
F
|
R
|
F
|
C
|
G
|
Q
|
R
|
N
|
Q
|
40 |
T
|
Q
|
Q
|
S
|
T
|
L
|
H
|
Y
|
D
|
Q
|
50 |
S
|
S
|
E
|
P
|
H
|
I
|
F
|
V
|
W
|
N
|
60 |
T
|
E
|
E
|
T
|
L
|
T
|
I
|
R
|
A
|
P
|
70 |
F
|
L
|
A
|
A
|
P
|
D
|
I
|
P
|
R
|
F
|
80 |
F
|
P
|
E
|
P
|
R
|
G
|
L
|
Y
|
H
|
F
|
90 |
C
|
L
|
Y
|
W
|
S
|
R
|
H
|
T
|
G
|
R
|
100 |
L
|
H
|
L
|
R
|
Y
|
G
|
K
|
H
|
D
|
Y
|
110 |
L
|
L
|
S
|
S
|
Q
|
A
|
S
|
R
|
L
|
L
|
120 |
C
|
F
|
Q
|
K
|
Q
|
E
|
Q
|
S
|
L
|
K
|
130 |
Q
|
G
|
A
|
P
|
L
|
I
|
A
|
T
|
S
|
V
|
140 |
S
|
S
|
W
|
Q
|
I
|
P
|
Q
|
N
|
T
|
S
|
150 |
L
|
P
|
G
|
A
|
P
|
S
|
F
|
I
|
F
|
S
|
160 |
F
|
H
|
N
|
A
|
P
|
H
|
K
|
V
|
S
|
H
|
170 |
N
|
A
|
S
|
V
|
D
|
M
|
C
|
D
|
L
|
K
|
180 |
K
|
E
|
L
|
Q
|
Q
|
L
|
S
|
R
|
Y
|
L
|
190 |
Q
|
H
|
P
|
Q
|
K
|
A
|
A
|
K
|
R
|
P
|
200 |
T
|
A
|
A
|
F
|
I
|
S
|
Q
|
Q
|
L
|
Q
|
210 |
S
|
L
|
E
|
S
|
K
|
L
|
T
|
S
|
V
|
S
|
220 |
F
|
L
|
G
|
D
|
T
|
L
|
S
|
F
|
E
|
E
|
230 |
D
|
R
|
V
|
N
|
A
|
T
|
V
|
W
|
K
|
L
|
240 |
P
|
P
|
T
|
A
|
G
|
L
|
E
|
D
|
L
|
H
|
250 |
I
|
H
|
S
|
Q
|
K
|
E
|
E
|
E
|
Q
|
S
|
260 |
E
|
V
|
Q
|
A
|
Y
|
S
|
L
|
L
|
L
|
P
|
270 |
R
|
A
|
V
|
F
|
Q
|
Q
|
T
|
R
|
G
|
R
|
280 |
R
|
R
|
D
|
D
|
A
|
K
|
R
|
L
|
L
|
V
|
290 |
V
|
D
|
F
|
S
|
S
|
Q
|
A
|
L
|
F
|
Q
|
300 |
D
|
K
|
N
|
S
|
S
|
Q
|
V
|
L
|
G
|
E
|
310 |
K
|
V
|
L
|
G
|
I
|
V
|
V
|
Q
|
N
|
T
|
320 |
K
|
V
|
T
|
N
|
L
|
S
|
D
|
P
|
V
|
V
|
330 |
L
|
T
|
F
|
Q
|
H
|
Q
|
P
|
Q
|
P
|
K
|
340 |
N
|
V
|
T
|
L
|
Q
|
C
|
V
|
F
|
W
|
V
|
350 |
E
|
D
|
P
|
A
|
S
|
S
|
S
|
T
|
G
|
S
|
360 |
W
|
S
|
S
|
A
|
G
|
C
|
E
|
T
|
V
|
S
|
370 |
R
|
D
|
T
|
Q
|
T
|
S
|
C
|
L
|
C
|
N
|
380 |
H
|
L
|
T
|
Y
|
F
|
A
|
V
|
L
|
M
|
V
|
390 |
TM1 | |||||||||
S
|
S
|
T
|
E
|
V
|
E
|
A
|
T
|
H
|
K
|
400 |
H
|
Y
|
L
|
T
|
L
|
L
|
S
|
Y
|
V
|
G
|
410 |
C
|
V
|
I
|
S
|
A
|
L
|
A
|
C
|
V
|
F
|
420 |
T
|
I
|
A
|
A
|
Y
|
L
|
C
|
S
|
R
|
R
|
430 |
ICL1 | TM2 | ||||||||
K
|
S
|
R
|
D
|
Y
|
T
|
I
|
K
|
V
|
H
|
440 |
M
|
N
|
L
|
L
|
S
|
A
|
V
|
F
|
L
|
L
|
450 |
D
|
V
|
S
|
F
|
L
|
L
|
S
|
E
|
P
|
V
|
460 |
ECL1 | TM3 | ||||||||
A
|
L
|
T
|
G
|
S
|
E
|
A
|
A
|
C
|
R
|
470 |
T
|
S
|
A
|
M
|
F
|
L
|
H
|
F
|
S
|
L
|
480 |
L
|
A
|
C
|
L
|
S
|
W
|
M
|
G
|
L
|
E
|
490 |
G
|
Y
|
N
|
L
|
Y
|
R
|
L
|
V
|
V
|
E
|
500 |
ICL2 | TM4 | ||||||||
V
|
F
|
G
|
T
|
Y
|
V
|
P
|
G
|
Y
|
L
|
510 |
L
|
K
|
L
|
S
|
I
|
V
|
G
|
W
|
G
|
F
|
520 |
P
|
V
|
F
|
L
|
V
|
T
|
L
|
V
|
A
|
L
|
530 |
ECL2 | |||||||||
V
|
D
|
V
|
N
|
N
|
Y
|
G
|
P
|
I
|
I
|
540 |
L
|
A
|
V
|
R
|
R
|
T
|
P
|
E
|
R
|
V
|
550 |
T
|
Y
|
P
|
S
|
M
|
C
|
W
|
I
|
R
|
D
|
560 |
TM5 | |||||||||
S
|
L
|
V
|
S
|
Y
|
V
|
T
|
N
|
L
|
G
|
570 |
L
|
F
|
S
|
L
|
V
|
F
|
L
|
F
|
N
|
L
|
580 |
A
|
M
|
L
|
A
|
T
|
M
|
V
|
V
|
Q
|
I
|
590 |
ICL3 | |||||||||
L
|
R
|
L
|
R
|
P
|
H
|
S
|
Q
|
N
|
W
|
600 |
TM6 | |||||||||
P
|
H
|
V
|
L
|
T
|
L
|
L
|
G
|
L
|
S
|
610 |
L
|
V
|
L
|
G
|
L
|
P
|
W
|
A
|
L
|
V
|
620 |
ECL3 | TM7 | ||||||||
F
|
F
|
S
|
F
|
A
|
S
|
G
|
T
|
F
|
Q
|
630 |
L
|
V
|
I
|
L
|
Y
|
L
|
F
|
S
|
I
|
I
|
640 |
T
|
S
|
F
|
Q
|
G
|
F
|
L
|
I
|
F
|
L
|
650 |
W
|
Y
|
W
|
S
|
M
|
R
|
F
|
Q
|
A
|
Q
|
660 |
C-term | |||||||||
G
|
G
|
P
|
S
|
P
|
L
|
K
|
N
|
N
|
S
|
670 |
D
|
S
|
A
|
K
|
L
|
P
|
I
|
S
|
S
|
G
|
680 |
S
|
T
|
S
|
S
|
S
|
R
|
I
|
LINKS
DIAGRAMS
GAIN domain
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available