C5a2 receptor (c5ar2_mouse)
FAMILY
Class A (Rhodopsin) Peptide receptors Complement peptide receptors C5a2 receptor
GENE
C5ar2 (C5l2, Gpr77)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
M
|
N
|
H
|
T
|
T
|
S
|
E
|
Y
|
Y
|
10 |
D
|
Y
|
E
|
Y
|
D
|
H
|
E
|
H
|
Y
|
S
|
20 |
D
|
L
|
P
|
D
|
V
|
P
|
V
|
D
|
C
|
P
|
30 |
TM1 | |||||||||
A
|
G
|
T
|
C
|
F
|
T
|
S
|
D
|
V
|
Y
|
40 |
L
|
I
|
V
|
L
|
L
|
V
|
L
|
Y
|
A
|
A
|
50 |
V
|
F
|
L
|
V
|
G
|
V
|
P
|
G
|
N
|
T
|
60 |
L
|
V
|
A
|
W
|
V
|
T
|
W
|
K
|
E
|
S
|
70 |
ICL1 | TM2 | ||||||||
R
|
H
|
R
|
L
|
G
|
A
|
S
|
W
|
F
|
L
|
80 |
H
|
L
|
T
|
M
|
A
|
D
|
L
|
L
|
C
|
C
|
90 |
V
|
S
|
L
|
P
|
F
|
L
|
A
|
V
|
P
|
I
|
100 |
ECL1 | |||||||||
A
|
Q
|
K
|
G
|
H
|
W
|
P
|
Y
|
G
|
A
|
110 |
TM3 | |||||||||
A
|
G
|
C
|
W
|
L
|
L
|
S
|
S
|
I
|
T
|
120 |
I
|
L
|
S
|
M
|
Y
|
A
|
S
|
V
|
L
|
L
|
130 |
L
|
T
|
G
|
L
|
S
|
G
|
D
|
L
|
F
|
L
|
140 |
ICL2 | |||||||||
L
|
A
|
F
|
R
|
P
|
S
|
W
|
K
|
G
|
A
|
150 |
TM4 | |||||||||
D
|
H
|
R
|
T
|
F
|
G
|
V
|
R
|
V
|
V
|
160 |
Q
|
A
|
S
|
S
|
W
|
M
|
L
|
G
|
L
|
L
|
170 |
L
|
T
|
V
|
P
|
S
|
A
|
V
|
Y
|
R
|
R
|
180 |
ECL2 | |||||||||
L
|
L
|
Q
|
E
|
H
|
Y
|
P
|
P
|
R
|
L
|
190 |
V
|
C
|
G
|
I
|
D
|
Y
|
G
|
G
|
S
|
V
|
200 |
TM5 | |||||||||
S
|
A
|
E
|
V
|
A
|
I
|
T
|
T
|
V
|
R
|
210 |
F
|
L
|
F
|
G
|
F
|
L
|
G
|
P
|
L
|
V
|
220 |
F
|
M
|
A
|
G
|
C
|
H
|
G
|
I
|
L
|
Q
|
230 |
ICL3 | TM6 | ||||||||
R
|
Q
|
M
|
A
|
R
|
R
|
H
|
W
|
P
|
L
|
240 |
G
|
T
|
A
|
V
|
V
|
V
|
G
|
F
|
F
|
I
|
250 |
C
|
W
|
T
|
P
|
Y
|
H
|
V
|
L
|
R
|
V
|
260 |
ECL3 | |||||||||
I
|
I
|
A
|
A
|
A
|
P
|
P
|
H
|
S
|
L
|
270 |
TM7 | |||||||||
L
|
L
|
A
|
R
|
V
|
L
|
E
|
A
|
E
|
P
|
280 |
L
|
F
|
N
|
G
|
L
|
A
|
L
|
A
|
H
|
S
|
290 |
A
|
L
|
N
|
P
|
I
|
M
|
F
|
L
|
Y
|
F
|
300 |
C-term | |||||||||
G
|
R
|
K
|
Q
|
L
|
C
|
K
|
S
|
L
|
Q
|
310 |
A
|
A
|
C
|
H
|
W
|
A
|
L
|
R
|
D
|
P
|
320 |
Q
|
D
|
E
|
E
|
S
|
A
|
V
|
T
|
K
|
V
|
330 |
S
|
I
|
S
|
T
|
S
|
H
|
E
|
M
|
V
|
S
|
340 |
E
|
M
|
P
|
V
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available