CCR10 (ccr10_mouse)

FAMILY

Class A (Rhodopsin) Protein receptors Chemokine receptors CCR10

GENE

Ccr10 (Cmkbr9, Gpr2)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

C-C chemokine receptor type 10, C-C CKR-10, CC-CKR-10, CCR-10, Chemokine C-C receptor 9, G-protein coupled receptor 2

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
G
T
K
P
T
E
Q
V
S
10
                   
W
G
L
Y
S
G
Y
D
E
E
20
                   
A
Y
S
V
G
P
L
P
E
L
30
              TM1
C
Y
K
A
D
V
Q
A
F
S
40
                   
R
A
F
Q
P
S
V
S
L
M
50
                   
V
A
V
L
G
L
A
G
N
G
60
                   
L
V
L
A
T
H
L
A
A
R
70
ICL1 TM2      
R
T
T
R
S
P
T
S
V
H
80
                   
L
L
Q
L
A
L
A
D
L
L
90
                   
L
A
L
T
L
P
F
A
A
A
100
        ECL1    
G
A
L
Q
G
W
N
L
G
S
110
TM3              
T
T
C
R
A
I
S
G
L
Y
120
                   
S
A
S
F
H
A
G
F
L
F
130
                   
L
A
C
I
S
A
D
R
Y
V
140
        ICL2    
A
I
A
R
A
L
P
A
G
Q
150
      TM4        
R
P
S
T
P
S
R
A
H
L
160
                   
V
S
V
F
V
W
L
L
S
L
170
                   
F
L
A
L
P
A
L
L
F
S
180
ECL2            
R
D
G
P
R
E
G
Q
R
R
190
                   
C
R
L
I
F
P
E
S
L
T
200
  TM5            
Q
T
V
K
G
A
S
A
V
A
210
                   
Q
V
V
L
G
F
A
L
P
L
220
                   
G
V
M
A
A
C
Y
A
L
L
230
                   
G
R
T
L
L
A
A
R
G
P
240
TM6              
E
R
R
R
A
L
R
V
V
V
250
                   
A
L
V
V
A
F
V
V
L
Q
260
                   
L
P
Y
S
L
A
L
L
L
D
270
                   
T
A
D
L
L
A
A
R
E
R
280
TM7              
S
C
S
S
S
K
R
K
D
L
290
                   
A
L
L
V
T
G
G
L
T
L
300
                   
V
R
C
S
L
N
P
V
L
Y
310
      H8          
A
F
L
G
L
R
F
R
R
D
320
                   
L
R
R
L
L
Q
G
G
G
C
330
C-term        
S
P
K
P
N
P
R
G
R
C
340
                   
P
R
R
L
R
L
S
S
C
S
350
                   
A
P
T
E
T
H
S
L
S
W
360
   
D
N

LINKS

Guide To Pharmacology

UniProt

DIAGRAMS

7TM

ICL1 R R T T ICL1ECL1 G W N L ECL1ICL2 A L P A G Q R P S ICL2ECL2 R D G P R E G Q R R C R L I F P E S L T Q ECL2ICL3 R G ICL3ECL3 R E R ECL3N-term M G T K P T E Q V S W G L Y S G Y D E E A Y S V G P L P E L C Y K A D V Q N-termC-term G G G C S P K P N P R G R C P R R L R L S S C S A P T E T H S L S W D N C-term A F S R A F Q P S V S L M V A V L G L A G N G L V L A T H L A A R S P T S V H L L Q L A L A D L L L A L T L P F A A A G A L Q G S T T C R A I S G L Y S A S F H A G F L F L A C I S A D R Y V A I A R T P S R A H L V S V F V W L L S L F L A L P A L L F S T V K G A S A V A Q V V L G F A L P L G V M A A C Y A L L G R T L L A A P E R R R A L R V V V A L V V A F V V L Q L P Y S L A L L L D T A D L L A A S C S S S K R K D L A L L V T G G L T L V R C S L N P V L Y A F L G L R L R R F R R D L L Q
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N G A L G L V A V M L S V S P Q F A R 1 L Q L A L A D L L L A L T L P F A A A G 2 C A L F L F G A H F S A S Y L G S I A R 3 A H L V S V F V W L L S L F L A L P A 4 Y C A A M V G L P L A F G L V V Q A V A S 5 V A L V V A F V V L Q L P Y S L A L L L 6 V P N L S C R V L T L G G T V L L A L 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available