CysLT2 receptor (cltr2_mouse)
FAMILY
Class A (Rhodopsin) Lipid receptors Leukotriene receptors CysLT2 receptor
GENE
Cysltr2 (Cyslt2)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Cysteinyl leukotriene receptor 2, CysLTR2
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
V
|
T
|
G
|
T
|
P
|
S
|
S
|
Y
|
10 |
TM1 | |||||||||
S
|
N
|
R
|
N
|
C
|
T
|
I
|
E
|
N
|
F
|
20 |
K
|
K
|
E
|
F
|
Y
|
P
|
I
|
I
|
Y
|
L
|
30 |
I
|
I
|
F
|
F
|
W
|
G
|
A
|
L
|
G
|
N
|
40 |
G
|
F
|
S
|
I
|
Y
|
V
|
F
|
L
|
Q
|
T
|
50 |
ICL1 | TM2 | ||||||||
C
|
K
|
K
|
S
|
T
|
S
|
V
|
N
|
V
|
F
|
60 |
M
|
L
|
N
|
L
|
A
|
T
|
S
|
D
|
F
|
L
|
70 |
F
|
I
|
S
|
T
|
L
|
P
|
F
|
R
|
A
|
D
|
80 |
ECL1 | |||||||||
Y
|
Y
|
F
|
R
|
G
|
S
|
N
|
W
|
I
|
F
|
90 |
TM3 | |||||||||
G
|
D
|
L
|
A
|
C
|
R
|
V
|
M
|
S
|
Y
|
100 |
S
|
L
|
Y
|
V
|
N
|
M
|
Y
|
T
|
S
|
I
|
110 |
Y
|
F
|
L
|
T
|
V
|
L
|
S
|
V
|
V
|
R
|
120 |
ICL2 | |||||||||
F
|
L
|
A
|
T
|
V
|
H
|
P
|
F
|
R
|
M
|
130 |
TM4 | |||||||||
F
|
H
|
V
|
T
|
S
|
V
|
R
|
S
|
A
|
W
|
140 |
I
|
L
|
C
|
G
|
I
|
I
|
W
|
V
|
F
|
I
|
150 |
M
|
A
|
S
|
S
|
A
|
L
|
L
|
L
|
V
|
N
|
160 |
ECL2 | |||||||||
G
|
Q
|
E
|
E
|
K
|
D
|
N
|
I
|
I
|
S
|
170 |
C
|
L
|
E
|
L
|
S
|
P
|
Q
|
K
|
F
|
K
|
180 |
TM5 | |||||||||
S
|
L
|
L
|
I
|
M
|
N
|
H
|
I
|
A
|
V
|
190 |
A
|
V
|
G
|
F
|
L
|
L
|
P
|
F
|
L
|
T
|
200 |
L
|
T
|
V
|
C
|
Y
|
L
|
L
|
I
|
I
|
R
|
210 |
ICL3 | |||||||||
I
|
L
|
L
|
K
|
A
|
E
|
I
|
P
|
E
|
S
|
220 |
TM6 | |||||||||
G
|
P
|
R
|
A
|
A
|
H
|
R
|
K
|
A
|
L
|
230 |
T
|
T
|
I
|
V
|
I
|
A
|
M
|
I
|
T
|
F
|
240 |
L
|
L
|
C
|
F
|
L
|
P
|
Y
|
H
|
A
|
L
|
250 |
R
|
T
|
L
|
H
|
L
|
V
|
T
|
W
|
D
|
K
|
260 |
ECL3 | TM7 | ||||||||
D
|
S
|
C
|
G
|
D
|
V
|
L
|
H
|
K
|
A
|
270 |
T
|
V
|
I
|
T
|
L
|
T
|
M
|
A
|
A
|
A
|
280 |
N
|
S
|
C
|
F
|
N
|
P
|
F
|
L
|
Y
|
Y
|
290 |
H8 | |||||||||
F
|
A
|
G
|
E
|
N
|
F
|
K
|
A
|
R
|
L
|
300 |
R
|
A
|
I
|
F
|
S
|
K
|
V
|
H
|
L
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available