FFA2 receptor (ffar2_mouse)
FAMILY
Class A (Rhodopsin) Lipid receptors Free fatty acid receptors FFA2 receptor
GENE
Ffar2 (Gpr43, Lssig)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Free fatty acid receptor 2, G-protein coupled receptor 43, Leukocyte-specific STAT-induced GPCR
SOURCE
SWISSPROT
SEQUENCE
N-term | TM1 | ||||||||
M
|
T
|
P
|
D
|
W
|
H
|
S
|
S
|
L
|
I
|
10 |
L
|
T
|
A
|
Y
|
I
|
L
|
I
|
F
|
L
|
T
|
20 |
G
|
L
|
P
|
A
|
N
|
L
|
L
|
A
|
L
|
R
|
30 |
A
|
F
|
M
|
G
|
R
|
V
|
R
|
Q
|
P
|
Q
|
40 |
ICL1 | TM2 | ||||||||
P
|
A
|
P
|
V
|
H
|
I
|
L
|
L
|
L
|
N
|
50 |
L
|
T
|
L
|
A
|
D
|
L
|
L
|
L
|
L
|
L
|
60 |
L
|
L
|
P
|
F
|
R
|
I
|
V
|
E
|
A
|
A
|
70 |
ECL1 | TM3 | ||||||||
S
|
N
|
F
|
R
|
W
|
Y
|
L
|
P
|
K
|
I
|
80 |
V
|
C
|
A
|
L
|
T
|
G
|
F
|
G
|
F
|
Y
|
90 |
S
|
S
|
I
|
Y
|
C
|
S
|
T
|
W
|
L
|
L
|
100 |
A
|
G
|
I
|
S
|
M
|
E
|
R
|
Y
|
L
|
G
|
110 |
ICL2 | |||||||||
V
|
A
|
F
|
P
|
V
|
Q
|
Y
|
K
|
L
|
S
|
120 |
TM4 | |||||||||
R
|
R
|
P
|
L
|
Y
|
G
|
V
|
I
|
A
|
A
|
130 |
L
|
V
|
A
|
W
|
I
|
M
|
S
|
F
|
G
|
H
|
140 |
C
|
T
|
I
|
V
|
I
|
I
|
V
|
Q
|
Y
|
L
|
150 |
ECL2 | |||||||||
N
|
S
|
T
|
E
|
Q
|
V
|
G
|
T
|
E
|
N
|
160 |
Q
|
I
|
T
|
C
|
Y
|
E
|
N
|
F
|
T
|
Q
|
170 |
TM5 | |||||||||
E
|
Q
|
L
|
D
|
V
|
V
|
L
|
P
|
V
|
R
|
180 |
L
|
E
|
L
|
C
|
L
|
V
|
L
|
F
|
F
|
V
|
190 |
P
|
M
|
A
|
V
|
T
|
I
|
F
|
C
|
Y
|
W
|
200 |
R
|
F
|
V
|
W
|
I
|
M
|
L
|
T
|
Q
|
P
|
210 |
ICL3 | TM6 | ||||||||
H
|
V
|
G
|
A
|
Q
|
R
|
R
|
R
|
R
|
A
|
220 |
V
|
G
|
L
|
A
|
V
|
V
|
T
|
L
|
L
|
N
|
230 |
F
|
L
|
V
|
C
|
F
|
G
|
P
|
Y
|
N
|
M
|
240 |
S
|
H
|
L
|
V
|
G
|
F
|
Y
|
L
|
R
|
Q
|
250 |
ECL3 | TM7 | ||||||||
S
|
P
|
S
|
W
|
R
|
V
|
E
|
A
|
V
|
V
|
260 |
F
|
S
|
S
|
L
|
N
|
A
|
S
|
L
|
D
|
P
|
270 |
H8 | |||||||||
L
|
L
|
F
|
Y
|
F
|
S
|
S
|
S
|
V
|
V
|
280 |
R
|
R
|
A
|
F
|
G
|
K
|
G
|
L
|
L
|
L
|
290 |
C-term | |||||||||
I
|
R
|
N
|
P
|
A
|
S
|
S
|
M
|
L
|
G
|
300 |
R
|
G
|
A
|
K
|
E
|
T
|
V
|
E
|
G
|
T
|
310 |
K
|
M
|
D
|
R
|
G
|
G
|
S
|
Q
|
A
|
E
|
320 |
G
|
V
|
Q
|
S
|
S
|
E
|
F
|
V
|
T
|
E
|
330 |
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available