GPR62 (gpr62_mouse)
FAMILY
Class A (Rhodopsin) Orphan receptors Class A orphans GPR62
GENE
Gpr62
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
G-protein coupled receptor 62
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
A
|
N
|
G
|
S
|
G
|
L
|
S
|
V
|
T
|
10 |
TM1 | |||||||||
E
|
L
|
A
|
G
|
S
|
V
|
G
|
F
|
I
|
L
|
20 |
A
|
V
|
L
|
V
|
E
|
V
|
G
|
A
|
V
|
L
|
30 |
G
|
N
|
G
|
T
|
L
|
L
|
V
|
V
|
V
|
L
|
40 |
ICL1 | TM2 | ||||||||
R
|
T
|
P
|
D
|
L
|
Q
|
D
|
A
|
F
|
Y
|
50 |
L
|
A
|
H
|
L
|
C
|
V
|
V
|
D
|
L
|
L
|
60 |
A
|
A
|
A
|
S
|
I
|
M
|
P
|
L
|
G
|
L
|
70 |
ECL1 | |||||||||
L
|
A
|
A
|
P
|
P
|
G
|
L
|
G
|
T
|
V
|
80 |
TM3 | |||||||||
P
|
L
|
D
|
P
|
S
|
S
|
C
|
R
|
A
|
A
|
90 |
R
|
F
|
L
|
S
|
A
|
A
|
L
|
L
|
P
|
A
|
100 |
C
|
T
|
L
|
G
|
V
|
A
|
A
|
L
|
G
|
L
|
110 |
A
|
R
|
Y
|
R
|
L
|
I
|
V
|
H
|
P
|
L
|
120 |
ICL2 | TM4 | ||||||||
R
|
P
|
G
|
A
|
R
|
P
|
A
|
P
|
A
|
L
|
130 |
V
|
L
|
T
|
A
|
V
|
W
|
S
|
A
|
A
|
A
|
140 |
L
|
L
|
G
|
A
|
L
|
S
|
L
|
L
|
G
|
P
|
150 |
ECL2 | |||||||||
P
|
P
|
A
|
P
|
P
|
P
|
A
|
P
|
A
|
R
|
160 |
TM5 | |||||||||
C
|
S
|
V
|
L
|
A
|
G
|
G
|
L
|
G
|
P
|
170 |
F
|
R
|
P
|
L
|
W
|
A
|
M
|
L
|
A
|
F
|
180 |
A
|
L
|
P
|
A
|
L
|
L
|
L
|
L
|
A
|
A
|
190 |
Y
|
G
|
S
|
I
|
F
|
L
|
V
|
A
|
R
|
R
|
200 |
A
|
A
|
L
|
R
|
P
|
P
|
R
|
G
|
T
|
R
|
210 |
ICL3 | |||||||||
P
|
R
|
S
|
D
|
S
|
L
|
D
|
S
|
R
|
L
|
220 |
TM6 | |||||||||
S
|
F
|
L
|
P
|
P
|
L
|
R
|
P
|
R
|
L
|
230 |
L
|
G
|
G
|
K
|
A
|
A
|
L
|
A
|
P
|
A
|
240 |
L
|
A
|
V
|
G
|
Q
|
F
|
A
|
A
|
C
|
W
|
250 |
L
|
P
|
Y
|
G
|
C
|
A
|
C
|
L
|
A
|
P
|
260 |
ECL3 | TM7 | ||||||||
A
|
A
|
R
|
A
|
A
|
A
|
A
|
E
|
A
|
T
|
270 |
V
|
T
|
W
|
V
|
A
|
Y
|
S
|
A
|
F
|
A
|
280 |
A
|
H
|
P
|
F
|
L
|
Y
|
G
|
L
|
L
|
Q
|
290 |
H8 | |||||||||
R
|
P
|
V
|
R
|
L
|
A
|
L
|
G
|
R
|
L
|
300 |
C-term | |||||||||
T
|
R
|
R
|
A
|
L
|
P
|
R
|
A
|
P
|
K
|
310 |
A
|
C
|
T
|
S
|
Q
|
A
|
W
|
H
|
L
|
Q
|
320 |
T
|
L
|
L
|
R
|
R
|
L
|
Q
|
E
|
L
|
R
|
330 |
K
|
D
|
P
|
V
|
L
|
G
|
P
|
S
|
E
|
A
|
340 |
P
|
E
|
Q
|
A
|
R
|
E
|
L
|
A
|
R
|
Q
|
350 |
T
|
P
|
S
|
V
|
S
|
E
|
A
|
T
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available