Y5 receptor (npy5r_mouse)
FAMILY
Class A (Rhodopsin) Peptide receptors Neuropeptide Y receptors Y5 receptor
GENE
Npy5r (Npy5)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
V
|
K
|
L
|
E
|
E
|
H
|
F
|
N
|
10 |
K
|
T
|
F
|
V
|
T
|
E
|
N
|
N
|
T
|
A
|
20 |
A
|
S
|
Q
|
N
|
T
|
A
|
S
|
P
|
A
|
W
|
30 |
E
|
D
|
Y
|
R
|
G
|
T
|
E
|
N
|
N
|
T
|
40 |
S
|
A
|
A
|
R
|
N
|
T
|
A
|
F
|
P
|
V
|
50 |
W
|
E
|
D
|
Y
|
R
|
G
|
S
|
V
|
D
|
D
|
60 |
TM1 | |||||||||
L
|
Q
|
Y
|
F
|
L
|
I
|
G
|
L
|
Y
|
T
|
70 |
F
|
V
|
S
|
L
|
L
|
G
|
F
|
M
|
G
|
N
|
80 |
L
|
L
|
I
|
L
|
M
|
A
|
V
|
M
|
K
|
K
|
90 |
ICL1 | TM2 | ||||||||
R
|
N
|
Q
|
K
|
T
|
T
|
V
|
N
|
F
|
L
|
100 |
I
|
G
|
N
|
L
|
A
|
F
|
S
|
D
|
I
|
L
|
110 |
V
|
V
|
L
|
F
|
C
|
S
|
P
|
F
|
T
|
L
|
120 |
ECL1 | |||||||||
T
|
S
|
V
|
L
|
L
|
D
|
Q
|
W
|
M
|
F
|
130 |
TM3 | |||||||||
G
|
K
|
A
|
M
|
C
|
H
|
I
|
M
|
P
|
F
|
140 |
L
|
Q
|
C
|
V
|
S
|
V
|
L
|
V
|
S
|
T
|
150 |
L
|
I
|
L
|
I
|
S
|
I
|
A
|
I
|
V
|
R
|
160 |
ICL2 | |||||||||
Y
|
H
|
M
|
I
|
K
|
H
|
P
|
I
|
S
|
N
|
170 |
TM4 | |||||||||
N
|
L
|
T
|
A
|
N
|
H
|
G
|
Y
|
F
|
L
|
180 |
I
|
A
|
T
|
V
|
W
|
T
|
L
|
G
|
F
|
A
|
190 |
I
|
C
|
S
|
P
|
L
|
P
|
V
|
F
|
H
|
S
|
200 |
ECL2 | |||||||||
L
|
V
|
E
|
L
|
K
|
E
|
T
|
F
|
G
|
S
|
210 |
A
|
L
|
L
|
S
|
S
|
K
|
Y
|
L
|
C
|
V
|
220 |
TM5 | |||||||||
E
|
S
|
W
|
P
|
S
|
D
|
S
|
Y
|
R
|
I
|
230 |
A
|
F
|
T
|
I
|
S
|
L
|
L
|
L
|
V
|
Q
|
240 |
Y
|
I
|
L
|
P
|
L
|
V
|
C
|
L
|
T
|
V
|
250 |
S
|
H
|
T
|
S
|
V
|
C
|
R
|
S
|
I
|
S
|
260 |
C
|
G
|
L
|
S
|
H
|
K
|
E
|
N
|
R
|
L
|
270 |
ICL3 | |||||||||
E
|
E
|
N
|
E
|
M
|
I
|
N
|
L
|
T
|
L
|
280 |
H
|
P
|
S
|
K
|
K
|
S
|
R
|
D
|
Q
|
A
|
290 |
K
|
P
|
P
|
S
|
T
|
Q
|
K
|
W
|
S
|
Y
|
300 |
S
|
F
|
I
|
R
|
K
|
H
|
R
|
R
|
R
|
Y
|
310 |
S
|
K
|
K
|
T
|
A
|
C
|
V
|
L
|
P
|
A
|
320 |
P
|
A
|
G
|
P
|
S
|
Q
|
E
|
K
|
H
|
L
|
330 |
T
|
V
|
P
|
E
|
N
|
P
|
G
|
S
|
V
|
R
|
340 |
S
|
Q
|
L
|
S
|
P
|
S
|
S
|
K
|
V
|
I
|
350 |
P
|
G
|
V
|
P
|
I
|
C
|
F
|
E
|
V
|
K
|
360 |
P
|
E
|
E
|
S
|
S
|
D
|
A
|
Q
|
E
|
M
|
370 |
TM6 | |||||||||
R
|
V
|
K
|
R
|
S
|
L
|
T
|
R
|
I
|
K
|
380 |
K
|
R
|
S
|
R
|
S
|
V
|
F
|
Y
|
R
|
L
|
390 |
T
|
I
|
L
|
I
|
L
|
V
|
F
|
A
|
V
|
S
|
400 |
W
|
M
|
P
|
L
|
H
|
V
|
F
|
H
|
V
|
V
|
410 |
ECL3 | |||||||||
T
|
D
|
F
|
N
|
D
|
N
|
L
|
I
|
S
|
N
|
420 |
TM7 | |||||||||
R
|
H
|
F
|
K
|
L
|
V
|
Y
|
C
|
I
|
C
|
430 |
H
|
L
|
L
|
G
|
M
|
M
|
S
|
C
|
C
|
L
|
440 |
H8 | |||||||||
N
|
P
|
I
|
L
|
Y
|
G
|
F
|
L
|
N
|
N
|
450 |
G
|
I
|
K
|
A
|
D
|
L
|
R
|
A
|
L
|
I
|
460 |
H
|
C
|
L
|
H
|
M
|
S
|
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available