P2Y1 receptor (p2ry1_mouse)
FAMILY
Class A (Rhodopsin) Nucleotide receptors P2Y receptors P2Y1 receptor
GENE
P2ry1
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
P2Y purinoceptor 1, P2Y1, ADP receptor, Purinergic receptor
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
T
|
E
|
V
|
P
|
W
|
S
|
V
|
V
|
P
|
10 |
N
|
G
|
T
|
D
|
A
|
A
|
F
|
L
|
A
|
G
|
20 |
L
|
G
|
S
|
L
|
W
|
G
|
N
|
S
|
T
|
V
|
30 |
A
|
S
|
T
|
A
|
A
|
V
|
S
|
S
|
S
|
F
|
40 |
Q
|
C
|
A
|
L
|
T
|
K
|
T
|
G
|
F
|
Q
|
50 |
TM1 | |||||||||
F
|
Y
|
Y
|
L
|
P
|
A
|
V
|
Y
|
I
|
L
|
60 |
V
|
F
|
I
|
I
|
G
|
F
|
L
|
G
|
N
|
S
|
70 |
V
|
A
|
I
|
W
|
M
|
F
|
V
|
F
|
H
|
M
|
80 |
ICL1 | TM2 | ||||||||
K
|
P
|
W
|
S
|
G
|
I
|
S
|
V
|
Y
|
M
|
90 |
F
|
N
|
L
|
A
|
L
|
A
|
D
|
F
|
L
|
Y
|
100 |
V
|
L
|
T
|
L
|
P
|
A
|
L
|
I
|
F
|
Y
|
110 |
ECL1 | |||||||||
Y
|
F
|
N
|
K
|
T
|
D
|
W
|
I
|
F
|
G
|
120 |
TM3 | |||||||||
D
|
A
|
M
|
C
|
K
|
L
|
Q
|
R
|
F
|
I
|
130 |
F
|
H
|
V
|
N
|
L
|
Y
|
G
|
S
|
I
|
L
|
140 |
F
|
L
|
T
|
C
|
I
|
S
|
A
|
H
|
R
|
Y
|
150 |
ICL2 | |||||||||
S
|
G
|
V
|
V
|
Y
|
P
|
L
|
K
|
S
|
L
|
160 |
TM4 | |||||||||
G
|
R
|
L
|
K
|
K
|
K
|
N
|
A
|
I
|
Y
|
170 |
V
|
S
|
V
|
L
|
V
|
W
|
L
|
I
|
V
|
V
|
180 |
V
|
A
|
I
|
S
|
P
|
I
|
L
|
F
|
Y
|
S
|
190 |
ECL2 | |||||||||
G
|
T
|
G
|
T
|
R
|
K
|
N
|
K
|
T
|
V
|
200 |
T
|
C
|
Y
|
D
|
T
|
T
|
S
|
N
|
D
|
Y
|
210 |
TM5 | |||||||||
L
|
R
|
S
|
Y
|
F
|
I
|
Y
|
S
|
M
|
C
|
220 |
T
|
T
|
V
|
A
|
M
|
F
|
C
|
I
|
P
|
L
|
230 |
V
|
L
|
I
|
L
|
G
|
C
|
Y
|
G
|
L
|
I
|
240 |
V
|
K
|
A
|
L
|
I
|
Y
|
N
|
D
|
L
|
D
|
250 |
ICL3 | TM6 | ||||||||
N
|
S
|
P
|
L
|
R
|
R
|
K
|
S
|
I
|
Y
|
260 |
L
|
V
|
I
|
I
|
V
|
L
|
T
|
V
|
F
|
A
|
270 |
V
|
S
|
Y
|
I
|
P
|
F
|
H
|
V
|
M
|
K
|
280 |
T
|
M
|
N
|
L
|
R
|
A
|
R
|
L
|
D
|
F
|
290 |
ECL3 | TM7 | ||||||||
Q
|
T
|
P
|
E
|
M
|
C
|
D
|
F
|
N
|
D
|
300 |
R
|
V
|
Y
|
A
|
T
|
Y
|
Q
|
V
|
T
|
R
|
310 |
G
|
L
|
A
|
S
|
L
|
N
|
S
|
C
|
V
|
D
|
320 |
H8 | |||||||||
P
|
I
|
L
|
Y
|
F
|
L
|
A
|
G
|
D
|
T
|
330 |
F
|
R
|
R
|
R
|
L
|
S
|
R
|
A
|
T
|
R
|
340 |
C-term | |||||||||
K
|
A
|
S
|
R
|
R
|
S
|
E
|
A
|
N
|
L
|
350 |
Q
|
S
|
K
|
S
|
E
|
E
|
M
|
T
|
L
|
N
|
360 |
I
|
L
|
S
|
E
|
F
|
K
|
Q
|
N
|
G
|
D
|
370 |
T
|
S
|
L
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available