CCR8 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 1.01 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR5 (sequence similarity: 66%) PDB: 5UIW

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 92.0 2.3 5.7
Side-chains 40.3 43.7 16.0

Number of backbone templates: 4
Number of rotamer templates: 38

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5UIW
4MBS
4ZUD
4XT1
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 22 CCR5 5UIW CCR5 5UIW
N-term 23 CCR5 5UIW CCR5 5UIW
N-term 24 CCR5 5UIW CCR5 5UIW
N-term 25 CCR5 5UIW CCR5 5UIW
N-term 26 CCR5 5UIW CCR5 5UIW
TM1 27 1.24x24 CCR5 5UIW - -
TM1 28 1.25x25 CCR5 5UIW CXCR4 4RWS
TM1 29 1.26x26 CCR5 5UIW - -
TM1 30 1.27x27 CCR5 5UIW ETB receptor 5X93
TM1 31 1.28x28 CCR5 5UIW - -
TM1 32 1.29x29 CCR5 5UIW BLT1 receptor 5X33
TM1 33 1.30x30 CCR5 5UIW - -
TM1 34 1.31x31 CCR5 5UIW CCR2 5T1A
TM1 35 1.32x32 CCR5 5UIW CXCR4 3ODU
TM1 36 1.33x33 CCR5 5UIW BLT1 receptor 5X33
TM1 37 1.34x34 CCR5 5UIW CCR5 5UIW
TM1 38 1.35x35 CCR5 5UIW CCR5 5UIW
TM1 39 1.36x36 CCR5 5UIW Y1 receptor 5ZBH
TM1 40 1.37x37 CCR5 5UIW C5a1 receptor 5O9H
TM1 41 1.38x38 CCR5 5UIW - -
TM1 42 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 43 1.40x40 CCR5 5UIW ETB receptor 5X93
TM1 44 1.41x41 CCR5 5UIW CCR5 5UIW
TM1 45 1.42x42 CCR5 5UIW M3 receptor 4U15
TM1 46 1.43x43 CCR5 5UIW CCR5 5UIW
TM1 47 1.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM1 48 1.45x45 CCR5 5UIW CCR5 5UIW
TM1 49 1.46x46 CCR5 5UIW A1 receptor 5UEN
TM1 50 1.47x47 CCR5 5UIW κ receptor 4DJH
TM1 51 1.48x48 CCR5 5UIW CCR9 5LWE
TM1 52 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 53 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 54 1.51x51 CCR5 5UIW CCR9 5LWE
TM1 55 1.52x52 CCR5 5UIW CCR5 5UIW
TM1 56 1.53x53 CCR5 5UIW CCR5 5UIW
TM1 57 1.54x54 CCR5 5UIW CCR5 5UIW
TM1 58 1.55x55 CCR5 5UIW CCR5 5UIW
TM1 59 1.56x56 CCR5 5UIW CXCR4 3ODU
TM1 60 1.57x57 CCR5 5UIW CCR5 5UIW
TM1 61 1.58x58 CCR5 5UIW δ receptor 4N6H
TM1 62 1.59x59 CCR5 5UIW M3 receptor 4U15
TM1 63 1.60x60 CCR5 5UIW CCR2 5T1A
ICL1 64 12.48x48 - - - -
ICL1 65 12.49x49 AT1 receptor 4ZUD AT1 receptor 4YAY
ICL1 66 12.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ICL1 67 12.51x51 - - - -
TM2 68 2.37x37 CCR5 5UIW CCR5 5UIW
TM2 69 2.38x38 CCR5 5UIW C5a1 receptor 5O9H
TM2 70 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 71 2.40x40 CCR5 5UIW CCR5 5UIW
TM2 72 2.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM2 73 2.42x42 CCR5 5UIW CCR5 5UIW
TM2 74 2.43x43 CCR5 5UIW CCR5 5UIW
TM2 75 2.44x44 CCR5 5UIW CCR5 5UIW
TM2 76 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 77 2.46x46 CCR5 5UIW CCR5 5UIW
TM2 78 2.47x47 CCR5 5UIW CCR5 5UIW
TM2 79 2.48x48 CCR5 5UIW AT1 receptor 4ZUD
TM2 80 2.49x49 CCR5 5UIW CCR5 5UIW
TM2 81 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 82 2.51x51 CCR5 5UIW CCR5 5UIW
TM2 83 2.52x52 CCR5 5UIW CCR2 5T1A
TM2 84 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 85 2.54x54 CCR5 5UIW CXCR4 3ODU
TM2 86 2.55x55 CCR5 5UIW Rhodopsin 1GZM
TM2 87 2.56x56 CCR5 5UIW M3 receptor 4U15
TM2 88 2.57x57 CCR5 5UIW Rhodopsin 1GZM
TM2 89 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 90 2.59x59 CCR5 5UIW CCR5 5UIW
TM2 91 2.60x60 CCR5 5UIW κ receptor 4DJH
TM2 92 2.61x61 CCR5 5UIW M3 receptor 4U15
TM2 93 2.62x62 CCR5 5UIW ETB receptor 5X93
TM2 94 2.63x63 CCR5 5UIW CCR5 5UIW
TM2 95 2.64x64 CCR5 5UIW BLT1 receptor 5X33
TM2 96 2.65x65 CCR5 5UIW κ receptor 4DJH
TM2 97 2.66x66 CCR5 5UIW US28 5WB1
ECL1 98 23.49x49 CCR5 5UIW CCR5 5UIW
ECL1 99 23.50x50 CCR5 5UIW CCR5 5UIW
ECL1 100 23.51x51 CCR5 5UIW CCR2 5T1A
ECL1 101 23.52x52 CCR5 5UIW CCR5 5UIW
TM3 102 3.21x21 CCR5 5UIW CCR5 5UIW
TM3 103 3.22x22 CCR5 5UIW apelin receptor 5VBL
TM3 104 3.23x23 CCR5 5UIW κ receptor 4DJH
TM3 105 3.24x24 CCR5 5UIW CCR5 5UIW
TM3 106 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 107 3.26x26 CCR5 5UIW CCR2 5T1A
TM3 108 3.27x27 CCR5 5UIW CCR9 5LWE
TM3 109 3.28x28 CCR5 5UIW CXCR4 3ODU
TM3 110 3.29x29 CCR5 5UIW AT1 receptor 4ZUD
TM3 111 3.30x30 CCR5 5UIW CCR5 5UIW
TM3 112 3.31x31 CCR5 5UIW Rhodopsin 1GZM
TM3 113 3.32x32 CCR5 5UIW CCR5 5UIW
TM3 114 3.33x33 CCR5 5UIW κ receptor 4DJH
TM3 115 3.34x34 CCR5 5UIW CCR5 5UIW
TM3 116 3.35x35 CCR5 5UIW CCR5 5UIW
TM3 117 3.36x36 CCR5 5UIW CCR5 5UIW
TM3 118 3.37x37 CCR5 5UIW CXCR4 3ODU
TM3 119 3.38x38 CCR5 5UIW CCR5 5UIW
TM3 120 3.39x39 CCR5 5UIW CXCR4 3ODU
TM3 121 3.40x40 CCR5 5UIW - -
TM3 122 3.41x41 CCR5 5UIW CCR5 5UIW
TM3 123 3.42x42 CCR5 5UIW CCR5 5UIW
TM3 124 3.43x43 CCR5 5UIW CCR5 5UIW
TM3 125 3.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM3 126 3.45x45 CCR5 5UIW CCR5 5UIW
TM3 127 3.46x46 CCR5 5UIW κ receptor 4DJH
TM3 128 3.47x47 CCR5 5UIW CXCR4 3ODU
TM3 129 3.48x48 CCR5 5UIW CCR9 5LWE
TM3 130 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 131 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 132 3.51x51 CCR5 5UIW CCR5 5UIW
TM3 133 3.52x52 CCR5 5UIW CCR5 5UIW
TM3 134 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 135 3.54x54 CCR5 5UIW CCR5 5UIW
TM3 136 3.55x55 CCR5 5UIW CCR5 5UIW
TM3 137 3.56x56 CCR5 5UIW CCR5 5UIW
ICL2 138 34.50x50 CCR5 5UIW CCR5 5UIW
ICL2 139 34.51x51 CCR5 5UIW CCR5 4MBS
ICL2 140 34.52x52 CCR5 5UIW - -
ICL2 141 34.53x53 CCR5 5UIW CCR5 5UIW
ICL2 142 34.54x54 CCR5 5UIW CCR5 4MBS
ICL2 143 34.55x55 CCR5 5UIW BLT1 receptor 5X33
ICL2 144 34.56x56 CCR5 5UIW BLT1 receptor 5X33
ICL2 145 34.57x57 CCR5 5UIW CCR5 5UIW
TM4 146 4.38x38 CCR5 5UIW CCR5 5UIW
TM4 147 4.39x39 CCR5 5UIW - -
TM4 148 4.40x40 CCR5 5UIW μ receptor 4DKL
TM4 149 4.41x41 CCR5 5UIW M2 receptor 3UON
TM4 150 4.42x42 CCR5 5UIW CCR5 5UIW
TM4 151 4.43x43 CCR5 5UIW D2 receptor 6CM4
TM4 152 4.44x44 CCR5 5UIW - -
TM4 153 4.45x45 CCR5 5UIW BLT1 receptor 5X33
TM4 154 4.46x46 CCR5 5UIW CCR9 5LWE
TM4 155 4.47x47 CCR5 5UIW OX1 receptor 4ZJ8
TM4 156 4.48x48 CCR5 5UIW NOP receptor 5DHG
TM4 157 4.49x49 CCR5 5UIW CXCR4 3ODU
TM4 158 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 159 4.51x51 CCR5 5UIW CCR2 5T1A
TM4 160 4.52x52 CCR5 5UIW - -
TM4 161 4.53x53 CCR5 5UIW CCR5 5UIW
TM4 162 4.54x54 CCR5 5UIW 5-HT2C receptor 6BQH
TM4 163 4.55x55 CCR5 5UIW - -
TM4 164 4.56x56 CCR5 5UIW CCR5 5UIW
TM4 165 4.57x57 CCR5 5UIW CXCR4 3ODU
TM4 166 4.58x59 CCR5 5UIW CXCR4 3ODU
TM4 167 4.59x60 CCR5 5UIW CCR5 5UIW
TM4 168 4.60x61 CCR5 5UIW Rhodopsin 1GZM
TM4 169 4.61x62 CCR5 5UIW BLT1 receptor 5X33
TM4 170 4.62x63 CCR5 5UIW apelin receptor 5VBL
TM4 171 4.63x64 CCR5 5UIW CCR5 5UIW
TM4 172 4.64x65 CCR5 5UIW - -
ECL2 173 CCR5 5UIW - -
ECL2 174 CCR5 5UIW - -
ECL2 175 CCR5 5UIW - -
ECL2 176 CCR5 5UIW - -
ECL2 177 CCR5 5UIW CCR5 5UIW
ECL2 178 CCR5 5UIW - -
ECL2 179 CCR5 5UIW - -
ECL2 180 CCR5 5UIW - -
ECL2 181 CCR5 5UIW - -
ECL2 182 CCR5 5UIW - -
ECL2 183 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 184 45.51x51 CCR5 5UIW apelin receptor 5VBL
ECL2 185 45.52x52 CCR5 5UIW CCR5 5UIW
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
TM5 190 5.30x31 CCR5 5UIW CCR5 5UIW
TM5 191 5.31x32 CCR5 5UIW μ receptor 4DKL
TM5 192 5.32x33 CCR5 5UIW P2Y1 receptor 4XNW
TM5 193 5.33x34 CCR5 5UIW - -
TM5 194 5.34x35 CCR5 5UIW CCR5 5UIW
TM5 195 5.35x36 CCR5 5UIW CCR5 5UIW
TM5 196 5.36x37 CCR5 5UIW AT1 receptor 4ZUD
TM5 197 5.37x38 CCR5 5UIW CCR5 5UIW
TM5 198 5.38x39 CCR5 5UIW δ receptor 4N6H
TM5 199 5.39x40 CCR5 5UIW US28 4XT1
TM5 200 5.40x41 CCR5 5UIW CXCR4 3ODU
TM5 201 5.41x42 CCR5 5UIW CCR5 5UIW
TM5 202 5.42x43 CCR5 5UIW Rhodopsin 1GZM
TM5 203 5.43x44 CCR5 5UIW CCR2 5T1A
TM5 204 5.44x45 CCR5 5UIW CCR5 5UIW
TM5 205 5.45x46 CCR5 5UIW CCR5 5UIW
TM5 206 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 207 5.47x47 CCR5 5UIW CCR5 5UIW
TM5 208 5.48x48 CCR5 5UIW AT1 receptor 4ZUD
TM5 209 5.49x49 CCR5 5UIW κ receptor 4DJH
TM5 210 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 211 5.51x51 CCR5 5UIW AT1 receptor 4ZUD
TM5 212 5.52x52 CCR5 5UIW apelin receptor 5VBL
TM5 213 5.53x53 CCR5 5UIW CCR2 5T1A
TM5 214 5.54x54 CCR5 5UIW - -
TM5 215 5.55x55 CCR5 5UIW - -
TM5 216 5.56x56 CCR5 5UIW ETB receptor 5X93
TM5 217 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 218 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 219 5.59x59 CCR5 5UIW M4 receptor 5DSG
TM5 220 5.60x60 CCR5 5UIW Y1 receptor 5ZBH
TM5 221 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 222 5.62x62 CCR5 5UIW CCR5 5UIW
TM5 223 5.63x63 CCR5 5UIW 5-HT2B receptor 4IB4
TM5 224 5.64x64 CCR5 5UIW - -
TM5 225 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 226 5.66x66 CCR5 5UIW κ receptor 4DJH
TM5 227 5.67x67 CCR5 5UIW - -
TM5 228 5.68x68 US28 4XT1 - -
ICL3 229 - - - -
ICL3 230 - - - -
ICL3 231 - - - -
ICL3 232 - - - -
TM6 233 6.30x30 CCR5 5UIW CXCR4 3ODU
TM6 234 6.31x31 CCR5 5UIW C5a1 receptor 6C1R
TM6 235 6.32x32 CCR5 5UIW CXCR4 3ODU
TM6 236 6.33x33 CCR5 5UIW CCR2 5T1A
TM6 237 6.34x34 CCR5 5UIW - -
TM6 238 6.35x35 CCR5 5UIW CCR5 5UIW
TM6 239 6.36x36 CCR5 5UIW CCR5 5UIW
TM6 240 6.37x37 CCR5 5UIW κ receptor 4DJH
TM6 241 6.38x38 CCR5 5UIW κ receptor 4DJH
TM6 242 6.39x39 CCR5 5UIW CXCR4 3ODU
TM6 243 6.40x40 CCR5 5UIW CCR9 5LWE
TM6 244 6.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM6 245 6.42x42 CCR5 5UIW CCR5 5UIW
TM6 246 6.43x43 CCR5 5UIW CXCR4 3ODU
TM6 247 6.44x44 CCR5 5UIW - -
TM6 248 6.45x45 CCR5 5UIW Rhodopsin 1GZM
TM6 249 6.46x46 CCR5 5UIW CCR5 5UIW
TM6 250 6.47x47 CCR5 5UIW CCR5 5UIW
TM6 251 6.48x48 CCR5 5UIW CCR5 5UIW
TM6 252 6.49x49 CCR5 5UIW PAF receptor 5ZKP
TM6 253 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 254 6.51x51 CCR5 5UIW 5-HT2C receptor 6BQH
TM6 255 6.52x52 CCR5 5UIW CCR5 5UIW
TM6 256 6.53x53 CCR5 5UIW BLT1 receptor 5X33
TM6 257 6.54x54 CCR5 5UIW CCR5 5UIW
TM6 258 6.55x55 CCR5 5UIW CCR5 5UIW
TM6 259 6.56x56 CCR5 5UIW AT1 receptor 4ZUD
TM6 260 6.57x57 CCR5 5UIW CCR5 5UIW
TM6 261 6.58x58 CCR5 5UIW A2A receptor 3VG9
TM6 262 6.59x59 CCR5 5UIW CXCR4 3ODU
TM6 263 6.60x60 CCR5 5UIW AT1 receptor 4ZUD
TM6 264 6.61x61 CCR5 5UIW Rhodopsin 1GZM
TM6 265 6.62x62 CCR5 4MBS apelin receptor 5VBL
TM6 266 6.63x63 CCR5 4MBS AT2 receptor 5UNG
TM6 267 6.64x64 CCR5 4MBS - -
TM6 268 6.65x65 CCR5 4MBS - -
ECL3 269 - - - -
ECL3 270 - - - -
TM7 271 7.24x23 CCR5 5UIW CXCR4 3ODU
TM7 272 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 273 7.26x25 CCR5 5UIW CCR5 5UIW
TM7 274 7.27x26 CCR5 5UIW AT1 receptor 4ZUD
TM7 275 7.28x27 CCR5 5UIW CCR5 5UIW
TM7 276 7.29x28 CCR5 5UIW PAF receptor 5ZKP
TM7 277 7.30x29 CCR5 5UIW CCR2 5T1A
TM7 278 7.31x30 CCR5 5UIW CCR5 5UIW
TM7 279 7.32x31 CCR5 5UIW μ receptor 4DKL
TM7 280 7.33x32 CCR5 5UIW NTS1 receptor 4BUO
TM7 281 7.34x33 CCR5 5UIW CCR5 5UIW
TM7 282 7.35x34 CCR5 5UIW CCR2 5T1A
TM7 283 7.36x35 CCR5 5UIW δ receptor 4N6H
TM7 284 7.37x36 CCR5 5UIW CCR5 5UIW
TM7 285 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 286 7.39x38 CCR5 5UIW CCR5 5UIW
TM7 287 7.40x39 CCR5 5UIW FFA1 receptor 5TZY
TM7 288 7.41x40 CCR5 5UIW CCR9 5LWE
TM7 289 7.42x41 CCR5 5UIW apelin receptor 5VBL
TM7 290 7.43x42 CCR5 5UIW CXCR4 3ODU
TM7 291 7.44x43 CCR5 5UIW CCR5 5UIW
TM7 292 7.45x45 CCR5 5UIW CCR5 5UIW
TM7 293 7.46x46 CCR5 5UIW CCR5 5UIW
TM7 294 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 295 7.48x48 CCR5 5UIW Y1 receptor 5ZBH
TM7 296 7.49x49 CCR5 5UIW CCR5 5UIW
TM7 297 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 298 7.51x51 CCR5 5UIW CCR9 5LWE
TM7 299 7.52x52 CCR5 5UIW CCR5 5UIW
TM7 300 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 301 7.54x54 CCR5 5UIW CCR5 5UIW
TM7 302 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 303 7.56x56 CCR5 5UIW CCR5 5UIW
H8 304 8.47x47 CCR5 5UIW CCR5 5UIW
H8 305 8.48x48 CCR5 5UIW CCR5 4MBS
H8 306 8.49x49 CCR5 5UIW CCR2 5T1A
H8 307 8.50x50 CCR5 5UIW CCR5 5UIW
H8 308 8.51x51 CCR5 5UIW κ receptor 4DJH
H8 309 8.52x52 CCR5 5UIW D3 receptor 3PBL
H8 310 8.53x53 CCR5 5UIW PAR2 5NDD
H8 311 8.54x54 CCR5 5UIW CCR5 5UIW
H8 312 8.55x55 CCR5 5UIW CCR2 5T1A
H8 313 8.56x56 CCR5 5UIW β2-adrenoceptor 2RH1
H8 314 8.57x57 CCR5 5UIW D3 receptor 3PBL
H8 315 8.58x58 CCR5 5UIW CCR5 5UIW
H8 316 8.59x59 CCR5 5UIW CCR5 5UIW
C-term 317 - - - -
C-term 318 - - - -
C-term 319 - - - -
C-term 320 - - - -
C-term 321 - - - -