FPR3 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 10.18 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 47%) PDB: 5C1M

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 76.9 12.2 10.9
Side-chains 27.1 47.2 25.7

Number of backbone templates: 5
Number of rotamer templates: 37

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5C1M
4DKL
5O9H
4XES
3ODU
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 18 μ receptor 5C1M μ receptor 5C1M
N-term 19 μ receptor 5C1M μ receptor 5C1M
N-term 20 μ receptor 5C1M μ receptor 5C1M
N-term 21 μ receptor 5C1M μ receptor 5C1M
N-term 22 μ receptor 5C1M μ receptor 5C1M
TM1 23 1.29x29 μ receptor 5C1M M2 receptor 4MQT
TM1 24 1.30x30 μ receptor 5C1M μ receptor 5C1M
TM1 25 1.31x31 μ receptor 5C1M NOP receptor 5DHG
TM1 26 1.32x32 μ receptor 5C1M - -
TM1 27 1.33x33 μ receptor 5C1M μ receptor 5C1M
TM1 28 1.34x34 μ receptor 5C1M M2 receptor 4MQT
TM1 29 1.35x35 μ receptor 5C1M FFA1 receptor 5TZY
TM1 30 1.36x36 μ receptor 5C1M US28 4XT1
TM1 31 1.37x37 μ receptor 5C1M M2 receptor 4MQT
TM1 32 1.38x38 μ receptor 5C1M κ receptor 6B73
TM1 33 1.39x39 μ receptor 5C1M - -
TM1 34 1.40x40 μ receptor 5C1M US28 4XT1
TM1 35 1.41x41 μ receptor 5C1M κ receptor 6B73
TM1 36 1.42x42 μ receptor 5C1M - -
TM1 37 1.43x43 μ receptor 5C1M AT2 receptor 5UNG
TM1 38 1.44x44 μ receptor 5C1M μ receptor 5C1M
TM1 39 1.45x45 μ receptor 5C1M US28 4XT1
TM1 40 1.46x46 μ receptor 5C1M μ receptor 5C1M
TM1 41 1.47x47 μ receptor 5C1M β2-adrenoceptor 3SN6
TM1 42 1.48x48 μ receptor 5C1M AT2 receptor 5UNG
TM1 43 1.49x49 μ receptor 5C1M μ receptor 5C1M
TM1 44 1.50x50 μ receptor 5C1M μ receptor 5C1M
TM1 45 1.51x51 μ receptor 5C1M PAF receptor 5ZKP
TM1 46 1.52x52 μ receptor 5C1M μ receptor 5C1M
TM1 47 1.53x53 μ receptor 5C1M μ receptor 5C1M
TM1 48 1.54x54 μ receptor 5C1M US28 4XT1
TM1 49 1.55x55 μ receptor 5C1M PAF receptor 5ZKP
TM1 50 1.56x56 μ receptor 5C1M μ receptor 5C1M
TM1 51 1.57x57 μ receptor 5C1M FFA1 receptor 5TZY
TM1 52 1.58x58 μ receptor 5C1M CXCR4 3ODU
TM1 53 1.59x59 μ receptor 5C1M C5a1 receptor 5O9H
TM1 54 1.60x60 μ receptor 5C1M US28 4XT1
ICL1 55 - - - -
ICL1 56 C5a1 receptor 5O9H - -
ICL1 57 - - - -
TM2 58 2.37x37 μ receptor 5C1M μ receptor 5C1M
TM2 59 2.38x38 μ receptor 5C1M AT2 receptor 5UNG
TM2 60 2.39x39 μ receptor 5C1M M2 receptor 4MQT
TM2 61 2.40x40 μ receptor 5C1M LPA6 receptor 5XSZ
TM2 62 2.41x41 μ receptor 5C1M μ receptor 5C1M
TM2 63 2.42x42 μ receptor 5C1M - -
TM2 64 2.43x43 μ receptor 5C1M - -
TM2 65 2.44x44 μ receptor 5C1M Rhodopsin 5DYS
TM2 66 2.45x45 μ receptor 5C1M μ receptor 5C1M
TM2 67 2.46x46 μ receptor 5C1M μ receptor 5C1M
TM2 68 2.47x47 μ receptor 5C1M μ receptor 5C1M
TM2 69 2.48x48 μ receptor 5C1M μ receptor 5C1M
TM2 70 2.49x49 μ receptor 5C1M μ receptor 5C1M
TM2 71 2.50x50 μ receptor 5C1M μ receptor 5C1M
TM2 72 2.51x51 μ receptor 5C1M C5a1 receptor 5O9H
TM2 73 2.52x52 μ receptor 5C1M - -
TM2 74 2.53x53 μ receptor 5C1M US28 4XT1
TM2 75 2.54x54 μ receptor 5C1M 5-HT1B receptor 6G79
TM2 76 2.55x55 μ receptor 5C1M AT2 receptor 5UNG
TM2 77 2.56x56 μ receptor 5C1M CB1 receptor 5XRA
TM2 78 2.57x57 μ receptor 5C1M μ receptor 5C1M
TM2 79 2.58x58 μ receptor 5C1M μ receptor 5C1M
TM2 80 2.59x59 μ receptor 5C1M μ receptor 5C1M
TM2 81 2.60x60 μ receptor 5C1M LPA6 receptor 5XSZ
TM2 82 2.61x61 μ receptor 5C1M US28 4XT1
TM2 83 2.62x62 μ receptor 5C1M μ receptor 5C1M
TM2 84 2.63x63 μ receptor 5C1M C5a1 receptor 5O9H
TM2 85 2.64x64 μ receptor 5C1M - -
TM2 86 2.65x65 μ receptor 5C1M AT1 receptor 4ZUD
TM2 87 2.66x66 μ receptor 5C1M μ receptor 5C1M
TM2 88 2.67x67 C5a1 receptor 5O9H - -
ECL1 89 - - - -
ECL1 90 23.49x49 C5a1 receptor 5O9H H1 receptor 3RZE
ECL1 91 23.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 92 23.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 93 23.52x52 - - - -
TM3 94 3.21x21 μ receptor 5C1M μ receptor 5C1M
TM3 95 3.22x22 μ receptor 5C1M US28 5WB1
TM3 96 3.23x23 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 97 3.24x24 μ receptor 5C1M μ receptor 5C1M
TM3 98 3.25x25 μ receptor 5C1M μ receptor 5C1M
TM3 99 3.26x26 μ receptor 5C1M μ receptor 5C1M
TM3 100 3.27x27 μ receptor 5C1M US28 4XT1
TM3 101 3.28x28 μ receptor 5C1M μ receptor 5C1M
TM3 102 3.29x29 μ receptor 5C1M CXCR4 3ODU
TM3 103 3.30x30 μ receptor 5C1M CXCR4 3ODU
TM3 104 3.31x31 μ receptor 5C1M CCR9 5LWE
TM3 105 3.32x32 μ receptor 5C1M C5a1 receptor 5O9H
TM3 106 3.33x33 μ receptor 5C1M NTS1 receptor 5T04
TM3 107 3.34x34 μ receptor 5C1M PAF receptor 5ZKP
TM3 108 3.35x35 μ receptor 5C1M μ receptor 5C1M
TM3 109 3.36x36 μ receptor 5C1M CXCR4 3ODU
TM3 110 3.37x37 μ receptor 5C1M μ receptor 5C1M
TM3 111 3.38x38 μ receptor 5C1M OX2 receptor 5WS3
TM3 112 3.39x39 μ receptor 5C1M μ receptor 5C1M
TM3 113 3.40x40 μ receptor 5C1M PAF receptor 5ZKP
TM3 114 3.41x41 μ receptor 5C1M - -
TM3 115 3.42x42 μ receptor 5C1M C5a1 receptor 5O9H
TM3 116 3.43x43 μ receptor 5C1M AT2 receptor 5UNG
TM3 117 3.44x44 μ receptor 5C1M AT2 receptor 5UNG
TM3 118 3.45x45 μ receptor 5C1M M2 receptor 4MQT
TM3 119 3.46x46 μ receptor 5C1M US28 4XT1
TM3 120 3.47x47 μ receptor 5C1M US28 4XT1
TM3 121 3.48x48 μ receptor 5C1M US28 4XT1
TM3 122 3.49x49 μ receptor 5C1M μ receptor 5C1M
TM3 123 3.50x50 μ receptor 5C1M μ receptor 5C1M
TM3 124 3.51x51 μ receptor 5C1M - -
TM3 125 3.52x52 μ receptor 5C1M μ receptor 5C1M
TM3 126 3.53x53 μ receptor 5C1M M2 receptor 4MQT
TM3 127 3.54x54 μ receptor 5C1M μ receptor 5C1M
TM3 128 3.55x55 μ receptor 5C1M - -
TM3 129 3.56x56 μ receptor 5C1M μ receptor 5C1M
ICL2 130 34.50x50 - - - -
ICL2 131 34.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 132 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 133 34.53x53 C5a1 receptor 5O9H μ receptor 5C1M
ICL2 134 34.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 135 34.55x55 C5a1 receptor 5O9H C5a1 receptor 6C1R
ICL2 136 34.56x56 C5a1 receptor 5O9H - -
ICL2 137 34.57x57 - - - -
TM4 138 4.38x38 μ receptor 5C1M μ receptor 5C1M
TM4 139 4.39x39 μ receptor 5C1M AT1 receptor 4ZUD
TM4 140 4.40x40 μ receptor 5C1M NTS1 receptor 5T04
TM4 141 4.41x41 μ receptor 5C1M C5a1 receptor 5O9H
TM4 142 4.42x42 μ receptor 5C1M μ receptor 5C1M
TM4 143 4.43x43 μ receptor 5C1M μ receptor 5C1M
TM4 144 4.44x44 μ receptor 5C1M - -
TM4 145 4.45x45 μ receptor 5C1M μ receptor 5C1M
TM4 146 4.46x46 μ receptor 5C1M - -
TM4 147 4.47x47 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 148 4.48x48 μ receptor 5C1M A1 receptor 6D9H
TM4 149 4.49x49 μ receptor 5C1M apelin receptor 5VBL
TM4 150 4.50x50 μ receptor 5C1M μ receptor 5C1M
TM4 151 4.51x51 μ receptor 5C1M μ receptor 5C1M
TM4 152 4.52x52 μ receptor 5C1M US28 4XT1
TM4 153 4.53x53 μ receptor 5C1M - -
TM4 154 4.54x54 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 155 4.55x55 μ receptor 5C1M A1 receptor 6D9H
TM4 156 4.56x56 μ receptor 5C1M NTS1 receptor 5T04
TM4 157 4.57x57 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 158 4.58x59 C5a1 receptor 5O9H AT2 receptor 5UNG
TM4 159 4.59x60 μ receptor 5C1M AT2 receptor 5UNG
TM4 160 4.60x61 μ receptor 5C1M CCR5 5UIW
TM4 161 4.61x62 μ receptor 5C1M μ receptor 5C1M
TM4 162 4.62x63 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 163 4.63x64 μ receptor 5C1M - -
TM4 164 4.64x65 C5a1 receptor 5O9H - -
ECL2 165 μ receptor 5C1M μ receptor 5C1M
ECL2 166 μ receptor 5C1M μ receptor 5C1M
ECL2 167 μ receptor 5C1M - -
ECL2 168 μ receptor 5C1M - -
ECL2 169 μ receptor 5C1M - -
ECL2 170 μ receptor 5C1M - -
ECL2 171 μ receptor 5C1M - -
ECL2 172 μ receptor 5C1M - -
ECL2 173 μ receptor 5C1M - -
ECL2 174 μ receptor 5C1M - -
ECL2 175 - - - -
ECL2 176 45.50x50 μ receptor 5C1M μ receptor 5C1M
ECL2 177 45.51x51 μ receptor 5C1M AT2 receptor 5UNG
ECL2 178 45.52x52 μ receptor 5C1M β2-adrenoceptor 4LDE
ECL2 179 - - - -
ECL2 180 - - - -
ECL2 181 - - - -
ECL2 182 - - - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
TM5 194 5.31x32 μ receptor 5C1M - -
TM5 195 5.32x33 μ receptor 5C1M - -
TM5 196 5.33x34 μ receptor 5C1M - -
TM5 197 5.34x35 μ receptor 5C1M - -
TM5 198 5.35x36 μ receptor 5C1M PAR1 3VW7
TM5 199 5.36x37 μ receptor 5C1M NTS1 receptor 5T04
TM5 200 5.37x38 μ receptor 5C1M NTS1 receptor 5T04
TM5 201 5.38x39 μ receptor 5C1M 5-HT2B receptor 5TUD
TM5 202 5.39x40 μ receptor 5C1M CB1 receptor 5XRA
TM5 203 5.40x41 μ receptor 5C1M μ receptor 5C1M
TM5 204 5.41x42 μ receptor 5C1M Y1 receptor 5ZBH
TM5 205 5.42x43 μ receptor 5C1M CXCR4 3ODU
TM5 206 5.43x44 μ receptor 5C1M μ receptor 5C1M
TM5 207 5.44x45 μ receptor 5C1M μ receptor 5C1M
TM5 208 5.45x46 μ receptor 5C1M P2Y12 receptor 4NTJ
TM5 209 5.46x461 μ receptor 5C1M AT2 receptor 5UNG
TM5 210 5.47x47 μ receptor 5C1M μ receptor 5C1M
TM5 211 5.48x48 μ receptor 5C1M CB1 receptor 5XRA
TM5 212 5.49x49 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 213 5.50x50 μ receptor 5C1M μ receptor 5C1M
TM5 214 5.51x51 μ receptor 5C1M NTS1 receptor 5T04
TM5 215 5.52x52 μ receptor 5C1M US28 4XT1
TM5 216 5.53x53 μ receptor 5C1M μ receptor 5C1M
TM5 217 5.54x54 μ receptor 5C1M μ receptor 5C1M
TM5 218 5.55x55 μ receptor 5C1M μ receptor 5C1M
TM5 219 5.56x56 μ receptor 5C1M μ receptor 5C1M
TM5 220 5.57x57 μ receptor 5C1M μ receptor 5C1M
TM5 221 5.58x58 μ receptor 5C1M μ receptor 5C1M
TM5 222 5.59x59 μ receptor 5C1M μ receptor 5C1M
TM5 223 5.60x60 μ receptor 5C1M CXCR4 3ODU
TM5 224 5.61x61 μ receptor 5C1M AT2 receptor 5UNG
TM5 225 5.62x62 μ receptor 5C1M NTS1 receptor 5T04
TM5 226 5.63x63 μ receptor 5C1M A1 receptor 5N2S
TM5 227 5.64x64 μ receptor 5C1M NTS1 receptor 5T04
TM5 228 5.65x65 μ receptor 5C1M A1 receptor 6D9H
TM5 229 5.66x66 μ receptor 5C1M CB1 receptor 5XRA
TM5 230 5.67x67 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 231 5.68x68 μ receptor 5C1M - -
ICL3 232 - - - -
ICL3 233 - - - -
ICL3 234 - - - -
ICL3 235 - - - -
TM6 236 6.30x30 μ receptor 5C1M C5a1 receptor 6C1R
TM6 237 6.31x31 μ receptor 5C1M - -
TM6 238 6.32x32 μ receptor 5C1M μ receptor 5C1M
TM6 239 6.33x33 μ receptor 5C1M - -
TM6 240 6.34x34 μ receptor 5C1M AT2 receptor 5UNG
TM6 241 6.35x35 μ receptor 5C1M μ receptor 5C1M
TM6 242 6.36x36 μ receptor 5C1M US28 4XT1
TM6 243 6.37x37 μ receptor 5C1M - -
TM6 244 6.38x38 μ receptor 5C1M AT2 receptor 5UNG
TM6 245 6.39x39 μ receptor 5C1M AT2 receptor 5UNG
TM6 246 6.40x40 μ receptor 5C1M μ receptor 5C1M
TM6 247 6.41x41 μ receptor 5C1M μ receptor 5C1M
TM6 248 6.42x42 μ receptor 5C1M μ receptor 5C1M
TM6 249 6.43x43 μ receptor 5C1M C5a1 receptor 5O9H
TM6 250 6.44x44 μ receptor 5C1M μ receptor 5C1M
TM6 251 6.45x45 μ receptor 5C1M PAF receptor 5ZKP
TM6 252 6.46x46 μ receptor 5C1M AT2 receptor 5UNG
TM6 253 6.47x47 μ receptor 5C1M μ receptor 5C1M
TM6 254 6.48x48 μ receptor 5C1M μ receptor 5C1M
TM6 255 6.49x49 μ receptor 5C1M CCR9 5LWE
TM6 256 6.50x50 μ receptor 5C1M μ receptor 5C1M
TM6 257 6.51x51 μ receptor 5C1M US28 4XT1
TM6 258 6.52x52 μ receptor 5C1M - -
TM6 259 6.53x53 μ receptor 5C1M US28 4XT1
TM6 260 6.54x54 μ receptor 5C1M 5-HT1B receptor 6G79
TM6 261 6.55x55 μ receptor 5C1M C5a1 receptor 5O9H
TM6 262 6.56x56 μ receptor 5C1M μ receptor 5C1M
TM6 263 6.57x57 μ receptor 5C1M AT2 receptor 5UNG
TM6 264 6.58x58 μ receptor 5C1M 5-HT1B receptor 6G79
TM6 265 6.59x59 μ receptor 5C1M μ receptor 5C1M
TM6 266 6.60x60 μ receptor 5C1M OX2 receptor 5WS3
TM6 267 6.61x61 μ receptor 5C1M - -
ECL3 268 - - - -
ECL3 269 NTS1 receptor 4XES - -
ECL3 270 NTS1 receptor 4XES NTS1 receptor 4XES
ECL3 271 NTS1 receptor 4XES - -
ECL3 272 - - - -
TM7 273 7.24x23 CXCR4 3ODU - -
TM7 274 7.25x24 CXCR4 3ODU - -
TM7 275 7.26x25 CXCR4 3ODU - -
TM7 276 7.27x26 CXCR4 3ODU - -
TM7 277 7.28x27 μ receptor 5C1M - -
TM7 278 7.29x28 μ receptor 5C1M CB1 receptor 5XRA
TM7 279 7.30x29 μ receptor 5C1M AT1 receptor 4ZUD
TM7 280 7.31x30 μ receptor 5C1M AT2 receptor 5UNG
TM7 281 7.32x31 μ receptor 5C1M κ receptor 6B73
TM7 282 7.33x32 μ receptor 5C1M μ receptor 5C1M
TM7 283 7.34x33 μ receptor 5C1M 5-HT2B receptor 5TUD
TM7 284 7.35x34 μ receptor 5C1M CXCR4 3ODU
TM7 285 7.36x35 μ receptor 5C1M 5-HT2C receptor 6BQG
TM7 286 7.37x36 μ receptor 5C1M - -
TM7 287 7.38x37 μ receptor 5C1M US28 4XT1
TM7 288 7.39x38 μ receptor 5C1M CB1 receptor 5XRA
TM7 289 7.40x39 μ receptor 5C1M US28 4XT1
TM7 290 7.41x40 μ receptor 5C1M μ receptor 5C1M
TM7 291 7.42x41 μ receptor 5C1M US28 4XT1
TM7 292 7.43x42 μ receptor 5C1M AT2 receptor 5UNG
TM7 293 7.44x43 μ receptor 5C1M CXCR4 3ODU
TM7 294 7.45x45 μ receptor 5C1M μ receptor 5C1M
TM7 295 7.46x46 μ receptor 5C1M μ receptor 5C1M
TM7 296 7.47x47 μ receptor 5C1M μ receptor 5C1M
TM7 297 7.48x48 μ receptor 5C1M μ receptor 5C1M
TM7 298 7.49x49 μ receptor 5C1M μ receptor 5C1M
TM7 299 7.50x50 μ receptor 5C1M μ receptor 5C1M
TM7 300 7.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 301 7.52x52 C5a1 receptor 5O9H AT2 receptor 5UNG
TM7 302 7.53x53 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 303 7.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 304 7.55x55 C5a1 receptor 5O9H AT2 receptor 5UNG
TM7 305 7.56x56 C5a1 receptor 5O9H Rhodopsin 5DYS
H8 306 8.47x47 μ receptor 4DKL US28 4XT1
H8 307 8.48x48 μ receptor 4DKL A2A receptor 4UHR
H8 308 8.49x49 μ receptor 4DKL μ receptor 4DKL
H8 309 8.50x50 μ receptor 4DKL μ receptor 4DKL
H8 310 8.51x51 μ receptor 4DKL AT2 receptor 5UNF
H8 311 8.52x52 μ receptor 4DKL OX2 receptor 5WS3
H8 312 8.53x53 μ receptor 4DKL - -
H8 313 8.54x54 μ receptor 4DKL AT2 receptor 5UNG
H8 314 8.55x55 μ receptor 4DKL S1P1 receptor 3V2Y
H8 315 8.56x56 μ receptor 4DKL 5-HT2B receptor 5TUD
C-term 316 - - - -
C-term 317 - - - -
C-term 318 - - - -
C-term 319 - - - -
C-term 320 - - - -