GnRH1 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.14 docs)

VERSION

2018-07-10

MAIN TEMPLATE

OX2 receptor (sequence similarity: 40%) PDB: 5WS3

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 79.5 7.7 12.8
Side-chains 19.8 53.0 27.2

Number of backbone templates: 6
Number of rotamer templates: 42

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5WS3
4ZJ8
5VBL
3SN6
4UHR
5C1M
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 31 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 32 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 33 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 34 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 35 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 36 1.33x33 OX2 receptor 5WS3 S1P1 receptor 3V2Y
TM1 37 1.34x34 OX2 receptor 5WS3 κ receptor 4DJH
TM1 38 1.35x35 OX2 receptor 5WS3 - -
TM1 39 1.36x36 OX2 receptor 5WS3 NOP receptor 5DHG
TM1 40 1.37x37 OX2 receptor 5WS3 M4 receptor 5DSG
TM1 41 1.38x38 OX2 receptor 5WS3 κ receptor 4DJH
TM1 42 1.39x39 OX2 receptor 5WS3 M3 receptor 4U15
TM1 43 1.40x40 OX2 receptor 5WS3 Rhodopsin 1GZM
TM1 44 1.41x41 OX2 receptor 5WS3 M3 receptor 4U15
TM1 45 1.42x42 OX2 receptor 5WS3 M3 receptor 4U15
TM1 46 1.43x43 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 47 1.44x44 OX2 receptor 5WS3 apelin receptor 5VBL
TM1 48 1.45x45 OX2 receptor 5WS3 apelin receptor 5VBL
TM1 49 1.46x46 OX2 receptor 5WS3 A1 receptor 5UEN
TM1 50 1.47x47 OX2 receptor 5WS3 CCR9 5LWE
TM1 51 1.48x48 OX2 receptor 5WS3 apelin receptor 5VBL
TM1 52 1.49x49 OX2 receptor 5WS3 - -
TM1 53 1.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 54 1.51x51 OX2 receptor 5WS3 C5a1 receptor 5O9H
TM1 55 1.52x52 OX2 receptor 5WS3 - -
TM1 56 1.53x53 OX2 receptor 5WS3 - -
TM1 57 1.54x54 OX2 receptor 5WS3 apelin receptor 5VBL
TM1 58 1.55x55 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM1 59 1.56x56 OX2 receptor 5WS3 - -
TM1 60 1.57x57 OX2 receptor 5WS3 CCR5 5UIW
TM1 61 1.58x58 OX2 receptor 5WS3 - -
TM1 62 1.59x59 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 63 1.60x60 OX2 receptor 5WS3 - -
ICL1 64 - - - -
ICL1 65 - - - -
ICL1 66 - - - -
ICL1 67 - - - -
ICL1 68 - - - -
ICL1 69 - - - -
ICL1 70 - - - -
ICL1 71 12.48x48 OX2 receptor 5WS3 ETB receptor 5X93
ICL1 72 12.49x49 OX2 receptor 5WS3 H1 receptor 3RZE
ICL1 73 12.50x50 OX2 receptor 5WS3 H1 receptor 3RZE
ICL1 74 12.51x51 OX2 receptor 5WS3 - -
TM2 75 2.38x38 OX2 receptor 5WS3 - -
TM2 76 2.39x39 OX2 receptor 5WS3 S1P1 receptor 3V2Y
TM2 77 2.40x40 OX2 receptor 5WS3 PAF receptor 5ZKP
TM2 78 2.41x41 OX2 receptor 5WS3 H1 receptor 3RZE
TM2 79 2.42x42 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM2 80 2.43x43 OX2 receptor 5WS3 CCR5 5UIW
TM2 81 2.44x44 OX2 receptor 5WS3 P2Y12 receptor 4NTJ
TM2 82 2.45x45 OX2 receptor 5WS3 CXCR4 3ODU
TM2 83 2.46x46 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 84 2.47x47 OX2 receptor 5WS3 PAF receptor 5ZKP
TM2 85 2.48x48 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 86 2.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 87 2.50x50 OX2 receptor 5WS3 A2A receptor 5WF5
TM2 88 2.51x51 OX2 receptor 5WS3 apelin receptor 5VBL
TM2 89 2.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 90 2.53x53 OX2 receptor 5WS3 - -
TM2 91 2.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 92 2.55x55 OX2 receptor 5WS3 CCR5 5UIW
TM2 93 2.56x551 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM2 94 2.57x56 OX2 receptor 5WS3 H1 receptor 3RZE
TM2 95 2.58x57 OX2 receptor 5WS3 κ receptor 4DJH
TM2 96 2.59x58 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 97 2.60x59 OX2 receptor 5WS3 apelin receptor 5VBL
TM2 98 2.61x60 OX2 receptor 5WS3 - -
TM2 99 2.62x61 OX2 receptor 5WS3 NOP receptor 5DHG
TM2 100 2.63x62 OX2 receptor 5WS3 5-HT1B receptor 4IAQ
TM2 101 2.64x63 OX2 receptor 5WS3 - -
TM2 102 2.65x64 OX2 receptor 5WS3 A1 receptor 5UEN
TM2 103 2.66x65 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 104 - - - -
ECL1 105 - - - -
ECL1 106 23.49x49 OX2 receptor 5WS3 CCR5 5UIW
ECL1 107 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 108 23.51x51 OX2 receptor 5WS3 CXCR4 3ODU
ECL1 109 23.52x52 OX2 receptor 5WS3 - -
TM3 110 3.21x21 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 111 3.22x22 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM3 112 3.23x23 OX2 receptor 5WS3 M3 receptor 4U15
TM3 113 3.24x24 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 114 3.25x25 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 115 3.26x26 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 116 3.27x27 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 117 3.28x28 OX2 receptor 5WS3 CCR5 5UIW
TM3 118 3.29x29 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 119 3.30x30 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 120 3.31x31 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 121 3.32x32 OX2 receptor 5WS3 - -
TM3 122 3.33x33 OX2 receptor 5WS3 C5a1 receptor 5O9H
TM3 123 3.34x34 OX2 receptor 5WS3 AT1 receptor 4ZUD
TM3 124 3.35x35 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 125 3.36x36 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 126 3.37x37 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 127 3.38x38 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 128 3.39x39 OX2 receptor 5WS3 - -
TM3 129 3.40x40 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 130 3.41x41 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 131 3.42x42 OX2 receptor 5WS3 - -
TM3 132 3.43x43 OX2 receptor 5WS3 PAR1 3VW7
TM3 133 3.44x44 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM3 134 3.45x45 OX2 receptor 5WS3 M3 receptor 4U15
TM3 135 3.46x46 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 136 3.47x47 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 137 3.48x48 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 138 3.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 139 3.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 140 3.51x51 OX2 receptor 5WS3 BLT1 receptor 5X33
TM3 141 3.52x52 OX2 receptor 5WS3 apelin receptor 5VBL
TM3 142 3.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 143 3.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 144 3.55x55 OX2 receptor 5WS3 M3 receptor 4U15
TM3 145 3.56x56 OX2 receptor 5WS3 apelin receptor 5VBL
ICL2 146 34.50x50 - - - -
ICL2 147 34.51x51 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 148 34.52x52 OX1 receptor 4ZJ8 CB1 receptor 5TGZ
ICL2 149 34.53x53 OX1 receptor 4ZJ8 - -
ICL2 150 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 151 - - - -
TM4 152 4.38x38 OX2 receptor 5WS3 S1P1 receptor 3V2Y
TM4 153 4.39x39 OX2 receptor 5WS3 NOP receptor 5DHG
TM4 154 4.40x40 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 155 4.41x41 OX2 receptor 5WS3 AT1 receptor 4ZUD
TM4 156 4.42x42 OX2 receptor 5WS3 apelin receptor 5VBL
TM4 157 4.43x43 OX2 receptor 5WS3 NOP receptor 5DHG
TM4 158 4.44x44 OX2 receptor 5WS3 PAF receptor 5ZKQ
TM4 159 4.45x45 OX2 receptor 5WS3 M3 receptor 4U15
TM4 160 4.46x46 OX2 receptor 5WS3 Rhodopsin 1GZM
TM4 161 4.47x47 OX2 receptor 5WS3 M3 receptor 4U15
TM4 162 4.48x48 OX2 receptor 5WS3 ETB receptor 5X93
TM4 163 4.49x49 OX2 receptor 5WS3 H1 receptor 3RZE
TM4 164 4.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 165 4.51x51 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 166 4.52x52 OX2 receptor 5WS3 apelin receptor 5VBL
TM4 167 4.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 168 4.54x54 OX2 receptor 5WS3 κ receptor 4DJH
TM4 169 4.55x55 OX2 receptor 5WS3 ETB receptor 5X93
TM4 170 4.56x56 OX2 receptor 5WS3 - -
TM4 171 4.57x57 OX2 receptor 5WS3 apelin receptor 5VBL
TM4 172 4.58x59 OX2 receptor 5WS3 - -
TM4 173 4.59x60 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 174 4.60x61 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 175 4.61x62 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM4 176 4.62x63 OX2 receptor 5WS3 AT2 receptor 5UNG
TM4 177 4.63x64 OX2 receptor 5WS3 5-HT2C receptor 6BQH
TM4 178 4.64x65 OX2 receptor 5WS3 ETB receptor 5X93
ECL2 179 - - - -
ECL2 180 - - - -
ECL2 181 - - - -
ECL2 182 - - - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
ECL2 198 - - - -
ECL2 199 - - - -
ECL2 200 45.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL2 201 45.51x51 OX2 receptor 5WS3 κ receptor 4DJH
ECL2 202 45.52x52 OX2 receptor 5WS3 AT1 receptor 4ZUD
TM5 203 5.30x31 apelin receptor 5VBL apelin receptor 5VBL
TM5 204 5.31x32 apelin receptor 5VBL NOP receptor 5DHG
TM5 205 5.32x33 apelin receptor 5VBL apelin receptor 5VBL
TM5 206 5.33x34 OX2 receptor 5WS3 κ receptor 4DJH
TM5 207 5.34x35 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM5 208 5.35x36 OX2 receptor 5WS3 - -
TM5 209 5.36x37 OX2 receptor 5WS3 M2 receptor 3UON
TM5 210 5.37x38 OX2 receptor 5WS3 κ receptor 4DJH
TM5 211 5.38x39 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 212 5.39x40 OX2 receptor 5WS3 US28 4XT1
TM5 213 5.40x41 OX2 receptor 5WS3 M3 receptor 4U15
TM5 214 5.41x42 OX2 receptor 5WS3 BLT1 receptor 5X33
TM5 215 5.42x43 OX2 receptor 5WS3 H1 receptor 3RZE
TM5 216 5.43x44 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 217 5.44x45 OX2 receptor 5WS3 ETB receptor 5X93
TM5 218 5.45x46 OX2 receptor 5WS3 D4 receptor 5WIV
TM5 219 5.46x461 OX2 receptor 5WS3 FFA1 receptor 5TZY
TM5 220 5.47x47 OX2 receptor 5WS3 apelin receptor 5VBL
TM5 221 5.48x48 OX2 receptor 5WS3 μ receptor 4DKL
TM5 222 5.49x49 OX2 receptor 5WS3 κ receptor 4DJH
TM5 223 5.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 224 5.51x51 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 225 5.52x52 OX2 receptor 5WS3 PAR2 5NDD
TM5 226 5.53x53 OX2 receptor 5WS3 apelin receptor 5VBL
TM5 227 5.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 228 5.55x55 OX2 receptor 5WS3 apelin receptor 5VBL
TM5 229 5.56x56 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM5 230 5.57x57 OX2 receptor 5WS3 apelin receptor 5VBL
TM5 231 5.58x58 OX2 receptor 5WS3 NTS1 receptor 4BUO
TM5 232 5.59x59 OX2 receptor 5WS3 H1 receptor 3RZE
TM5 233 5.60x60 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM5 234 5.61x61 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 235 5.62x62 OX2 receptor 5WS3 κ receptor 4DJH
TM5 236 5.63x63 OX2 receptor 5WS3 Rhodopsin 1GZM
TM5 237 5.64x64 OX2 receptor 5WS3 apelin receptor 5VBL
TM5 238 5.65x65 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 239 5.66x66 OX2 receptor 5WS3 NTS1 receptor 4BUO
TM5 240 5.67x67 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM5 241 5.68x68 β2-adrenoceptor 3SN6 κ receptor 4DJH
TM5 242 5.69x69 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 243 5.70x70 β2-adrenoceptor 3SN6 NTS1 receptor 4BUO
TM5 244 5.71x71 β2-adrenoceptor 3SN6 A2A receptor 3VG9
TM5 245 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 246 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 247 5.74x74 β2-adrenoceptor 3SN6 - -
ICL3 248 - - - -
ICL3 249 A2A receptor 4UHR - -
ICL3 250 A2A receptor 4UHR - -
ICL3 251 A2A receptor 4UHR - -
ICL3 252 - - - -
TM6 253 6.21x21 A2A receptor 4UHR - -
TM6 254 6.22x22 A2A receptor 4UHR - -
TM6 255 6.23x23 A2A receptor 4UHR - -
TM6 256 6.24x24 A2A receptor 4UHR - -
TM6 257 6.25x25 OX2 receptor 5WS3 - -
TM6 258 6.26x26 OX2 receptor 5WS3 - -
TM6 259 6.27x27 OX2 receptor 5WS3 - -
TM6 260 6.28x28 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 261 6.29x29 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 262 6.30x30 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 263 6.31x31 OX2 receptor 5WS3 A1 receptor 5UEN
TM6 264 6.32x32 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 265 6.33x33 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 266 6.34x34 OX2 receptor 5WS3 apelin receptor 5VBL
TM6 267 6.35x35 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM6 268 6.36x36 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 269 6.37x37 OX2 receptor 5WS3 CCR9 5LWE
TM6 270 6.38x38 OX2 receptor 5WS3 apelin receptor 5VBL
TM6 271 6.39x39 OX2 receptor 5WS3 M3 receptor 4U15
TM6 272 6.40x40 OX2 receptor 5WS3 - -
TM6 273 6.41x41 OX2 receptor 5WS3 D2 receptor 6CM4
TM6 274 6.42x42 OX2 receptor 5WS3 CCR9 5LWE
TM6 275 6.43x43 OX2 receptor 5WS3 C5a1 receptor 5O9H
TM6 276 6.44x44 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 277 6.45x45 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM6 278 6.46x46 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM6 279 6.47x47 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 280 6.48x48 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM6 281 6.49x49 OX2 receptor 5WS3 κ receptor 4DJH
TM6 282 6.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 283 6.51x51 OX2 receptor 5WS3 apelin receptor 5VBL
TM6 284 6.52x52 OX2 receptor 5WS3 CXCR4 3ODU
TM6 285 6.53x53 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM6 286 6.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 287 6.55x55 OX2 receptor 5WS3 C5a1 receptor 5O9H
TM6 288 6.56x56 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM6 289 6.57x57 OX2 receptor 5WS3 - -
TM6 290 6.58x58 OX2 receptor 5WS3 apelin receptor 5VBL
TM6 291 6.59x59 OX2 receptor 5WS3 - -
TM6 292 6.60x60 OX2 receptor 5WS3 H1 receptor 3RZE
TM6 293 6.61x61 OX2 receptor 5WS3 CCR9 5LWE
ECL3 294 - - - -
ECL3 295 μ receptor 5C1M - -
ECL3 296 μ receptor 5C1M - -
ECL3 297 - - - -
TM7 298 7.28x27 OX2 receptor 5WS3 P2Y1 receptor 4XNW
TM7 299 7.29x28 OX2 receptor 5WS3 US28 4XT1
TM7 300 7.30x29 OX2 receptor 5WS3 δ receptor 4N6H
TM7 301 7.31x30 OX2 receptor 5WS3 - -
TM7 302 7.32x31 OX2 receptor 5WS3 CCR5 5UIW
TM7 303 7.33x32 OX2 receptor 5WS3 - -
TM7 304 7.34x33 OX2 receptor 5WS3 M4 receptor 5DSG
TM7 305 7.35x34 OX2 receptor 5WS3 - -
TM7 306 7.36x35 OX2 receptor 5WS3 μ receptor 4DKL
TM7 307 7.37x36 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 308 7.38x37 OX2 receptor 5WS3 5-HT2C receptor 6BQH
TM7 309 7.39x38 OX2 receptor 5WS3 - -
TM7 310 7.40x39 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 311 7.41x40 OX2 receptor 5WS3 C5a1 receptor 5O9H
TM7 312 7.42x41 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 313 7.43x42 OX2 receptor 5WS3 CCR9 5LWE
TM7 314 7.44x43 OX2 receptor 5WS3 ETB receptor 5X93
TM7 315 7.45x45 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 316 7.46x46 OX2 receptor 5WS3 - -
TM7 317 7.47x47 OX2 receptor 5WS3 apelin receptor 5VBL
TM7 318 7.48x48 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM7 319 7.49x49 OX2 receptor 5WS3 LPA6 receptor 5XSZ
TM7 320 7.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 321 7.51x51 OX2 receptor 5WS3 H1 receptor 3RZE
TM7 322 7.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 323 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 324 7.54x54 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 325 7.55x55 OX2 receptor 5WS3 A2A receptor 3VG9
TM7 326 7.56x56 OX2 receptor 5WS3 apelin receptor 5VBL
C-term 327 - - - -
C-term 328 - - - -