GPR183 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 0.98 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR5 (sequence similarity: 51%) PDB: 5UIW

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 85.0 8.8 6.2
Side-chains 25.5 52.6 21.9

Number of backbone templates: 8
Number of rotamer templates: 39

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5UIW
4ZUD
5VBL
5XSZ
4DJH
6B73
5C1M
4XNW
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 24 CCR5 5UIW CCR5 5UIW
N-term 25 CCR5 5UIW CCR5 5UIW
N-term 26 CCR5 5UIW CCR5 5UIW
N-term 27 CCR5 5UIW CCR5 5UIW
N-term 28 CCR5 5UIW CCR5 5UIW
TM1 29 1.30x30 CCR5 5UIW ETB receptor 5X93
TM1 30 1.31x31 CCR5 5UIW CCR5 5UIW
TM1 31 1.32x32 CCR5 5UIW - -
TM1 32 1.33x33 CCR5 5UIW μ receptor 4DKL
TM1 33 1.34x34 CCR5 5UIW OX2 receptor 5WS3
TM1 34 1.35x35 CCR5 5UIW β2-adrenoceptor 5JQH
TM1 35 1.36x36 CCR5 5UIW CCR5 5UIW
TM1 36 1.37x37 CCR5 5UIW Y1 receptor 5ZBH
TM1 37 1.38x38 CCR5 5UIW - -
TM1 38 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 39 1.40x40 CCR5 5UIW CCR5 5UIW
TM1 40 1.41x41 CCR5 5UIW CCR5 5UIW
TM1 41 1.42x42 CCR5 5UIW CCR5 5UIW
TM1 42 1.43x43 CCR5 5UIW CCR5 5UIW
TM1 43 1.44x44 CCR5 5UIW CCR5 5UIW
TM1 44 1.45x45 CCR5 5UIW P2Y1 receptor 4XNW
TM1 45 1.46x46 CCR5 5UIW CCR5 5UIW
TM1 46 1.47x47 CCR5 5UIW κ receptor 4DJH
TM1 47 1.48x48 CCR5 5UIW CCR5 5UIW
TM1 48 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 49 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 50 1.51x51 CCR5 5UIW H1 receptor 3RZE
TM1 51 1.52x52 CCR5 5UIW CCR5 5UIW
TM1 52 1.53x53 CCR5 5UIW LPA6 receptor 5XSZ
TM1 53 1.54x54 CCR5 5UIW apelin receptor 5VBL
TM1 54 1.55x55 CCR5 5UIW OX2 receptor 5WS3
TM1 55 1.56x56 CCR5 5UIW AT1 receptor 4ZUD
TM1 56 1.57x57 CCR5 5UIW κ receptor 4DJH
TM1 57 1.58x58 CCR5 5UIW μ receptor 4DKL
TM1 58 1.59x59 CCR5 5UIW Rhodopsin 1GZM
TM1 59 1.60x60 CCR5 5UIW - -
ICL1 60 12.48x48 - - - -
ICL1 61 12.49x49 AT1 receptor 4ZUD AT1 receptor 4YAY
ICL1 62 12.50x50 AT1 receptor 4ZUD - -
ICL1 63 12.51x51 - - - -
TM2 64 2.37x37 CCR5 5UIW 5-HT2C receptor 6BQH
TM2 65 2.38x38 CCR5 5UIW apelin receptor 5VBL
TM2 66 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 67 2.40x40 CCR5 5UIW LPA6 receptor 5XSZ
TM2 68 2.41x41 CCR5 5UIW BLT1 receptor 5X33
TM2 69 2.42x42 CCR5 5UIW CCR5 5UIW
TM2 70 2.43x43 CCR5 5UIW - -
TM2 71 2.44x44 CCR5 5UIW β2-adrenoceptor 5JQH
TM2 72 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 73 2.46x46 CCR5 5UIW CCR5 5UIW
TM2 74 2.47x47 CCR5 5UIW LPA6 receptor 5XSZ
TM2 75 2.48x48 CCR5 5UIW CCR5 5UIW
TM2 76 2.49x49 CCR5 5UIW CCR5 5UIW
TM2 77 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 78 2.51x51 CCR5 5UIW A2A receptor 3VG9
TM2 79 2.52x52 CCR5 5UIW κ receptor 4DJH
TM2 80 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 81 2.54x54 CCR5 5UIW κ receptor 4DJH
TM2 82 2.55x55 CCR5 5UIW κ receptor 4DJH
TM2 83 2.56x56 CCR5 5UIW NTS1 receptor 4BUO
TM2 84 2.57x57 CCR5 5UIW AT1 receptor 4ZUD
TM2 85 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 86 2.59x59 CCR5 5UIW Rhodopsin 1GZM
TM2 87 2.60x60 CCR5 5UIW LPA6 receptor 5XSZ
TM2 88 2.61x61 CCR5 5UIW H1 receptor 3RZE
TM2 89 2.62x62 CCR5 5UIW δ receptor 4N6H
TM2 90 2.63x63 CCR5 5UIW CCR5 5UIW
TM2 91 2.64x64 CCR5 5UIW κ receptor 4DJH
TM2 92 2.65x65 CCR5 5UIW CCR5 5UIW
TM2 93 2.66x66 CCR5 5UIW κ receptor 4DJH
TM2 94 2.67x67 apelin receptor 5VBL BLT1 receptor 5X33
ECL1 95 - - - -
ECL1 96 23.49x49 LPA6 receptor 5XSZ apelin receptor 5VBL
ECL1 97 23.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ECL1 98 23.51x51 LPA6 receptor 5XSZ LPA1 receptor 4Z35
ECL1 99 23.52x52 - - - -
TM3 100 3.21x21 CCR5 5UIW CCR5 5UIW
TM3 101 3.22x22 CCR5 5UIW κ receptor 4DJH
TM3 102 3.23x23 CCR5 5UIW CCR2 5T1A
TM3 103 3.24x24 CCR5 5UIW AT1 receptor 4ZUD
TM3 104 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 105 3.26x26 CCR5 5UIW BLT1 receptor 5X33
TM3 106 3.27x27 CCR5 5UIW AT1 receptor 4ZUD
TM3 107 3.28x28 CCR5 5UIW P2Y12 receptor 4NTJ
TM3 108 3.29x29 CCR5 5UIW A2A receptor 3VG9
TM3 109 3.30x30 CCR5 5UIW - -
TM3 110 3.31x31 CCR5 5UIW Y1 receptor 5ZBH
TM3 111 3.32x32 CCR5 5UIW LPA6 receptor 5XSZ
TM3 112 3.33x33 CCR5 5UIW κ receptor 4DJH
TM3 113 3.34x34 CCR5 5UIW CCR5 5UIW
TM3 114 3.35x35 CCR5 5UIW AT1 receptor 4ZUD
TM3 115 3.36x36 CCR5 5UIW NTS1 receptor 4BUO
TM3 116 3.37x37 CCR5 5UIW AT1 receptor 4ZUD
TM3 117 3.38x38 CCR5 5UIW AT1 receptor 4ZUD
TM3 118 3.39x39 CCR5 5UIW CCR5 5UIW
TM3 119 3.40x40 CCR5 5UIW AT1 receptor 4ZUD
TM3 120 3.41x41 CCR5 5UIW - -
TM3 121 3.42x42 CCR5 5UIW CCR5 5UIW
TM3 122 3.43x43 CCR5 5UIW PAR1 3VW7
TM3 123 3.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM3 124 3.45x45 CCR5 5UIW AT1 receptor 4ZUD
TM3 125 3.46x46 CCR5 5UIW CCR5 5UIW
TM3 126 3.47x47 CCR5 5UIW AT1 receptor 4ZUD
TM3 127 3.48x48 CCR5 5UIW CCR5 5UIW
TM3 128 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 129 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 130 3.51x51 CCR5 5UIW C5a1 receptor 5O9H
TM3 131 3.52x52 CCR5 5UIW κ receptor 4DJH
TM3 132 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 133 3.54x54 CCR5 5UIW CCR5 5UIW
TM3 134 3.55x55 CCR5 5UIW CCR5 5UIW
TM3 135 3.56x56 CCR5 5UIW CCR5 5UIW
ICL2 136 34.50x50 - - - -
ICL2 137 34.51x51 LPA6 receptor 5XSZ OX1 receptor 4ZJ8
ICL2 138 34.52x52 LPA6 receptor 5XSZ CCR9 5LWE
ICL2 139 34.53x53 LPA6 receptor 5XSZ M3 receptor 4U15
ICL2 140 34.54x54 LPA6 receptor 5XSZ A2A receptor 3VG9
ICL2 141 34.55x55 LPA6 receptor 5XSZ BLT1 receptor 5X33
ICL2 142 34.56x56 LPA6 receptor 5XSZ CB1 receptor 5TGZ
ICL2 143 34.57x57 - - - -
TM4 144 4.38x38 CCR5 5UIW FFA1 receptor 5TZY
TM4 145 4.39x39 CCR5 5UIW - -
TM4 146 4.40x40 CCR5 5UIW - -
TM4 147 4.41x41 CCR5 5UIW Y1 receptor 5ZBH
TM4 148 4.42x42 CCR5 5UIW AT1 receptor 4ZUD
TM4 149 4.43x43 CCR5 5UIW AT1 receptor 4ZUD
TM4 150 4.44x44 CCR5 5UIW OX1 receptor 4ZJ8
TM4 151 4.45x45 CCR5 5UIW μ receptor 4DKL
TM4 152 4.46x46 CCR5 5UIW AT1 receptor 4ZUD
TM4 153 4.47x47 CCR5 5UIW AT1 receptor 4ZUD
TM4 154 4.48x48 CCR5 5UIW Rhodopsin 1GZM
TM4 155 4.49x49 CCR5 5UIW CXCR4 3ODU
TM4 156 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 157 4.51x51 CCR5 5UIW μ receptor 4DKL
TM4 158 4.52x52 CCR5 5UIW AT1 receptor 4ZUD
TM4 159 4.53x53 CCR5 5UIW LPA6 receptor 5XSZ
TM4 160 4.54x54 CCR5 5UIW BLT1 receptor 5X33
TM4 161 4.55x55 CCR5 5UIW μ receptor 4DKL
TM4 162 4.56x56 CCR5 5UIW - -
TM4 163 4.57x57 CCR5 5UIW CXCR4 3ODU
TM4 164 4.58x59 CCR5 5UIW CCR5 5UIW
TM4 165 4.59x60 CCR5 5UIW CCR5 5UIW
TM4 166 4.60x61 CCR5 5UIW D2 receptor 6CM4
TM4 167 4.61x62 CCR5 5UIW BLT1 receptor 5X33
TM4 168 4.62x63 CCR5 5UIW CCR5 5UIW
TM4 169 4.63x64 CCR5 5UIW - -
TM4 170 4.64x65 CCR5 5UIW - -
ECL2 171 CCR5 5UIW - -
ECL2 172 CCR5 5UIW CCR5 5UIW
ECL2 173 CCR5 5UIW - -
ECL2 174 CCR5 5UIW - -
ECL2 175 CCR5 5UIW CCR5 5UIW
ECL2 176 CCR5 5UIW - -
ECL2 177 CCR5 5UIW - -
ECL2 178 CCR5 5UIW - -
ECL2 179 CCR5 5UIW - -
ECL2 180 CCR5 5UIW CCR5 5UIW
ECL2 181 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 182 45.51x51 CCR5 5UIW δ receptor 4N6H
ECL2 183 45.52x52 CCR5 5UIW OX2 receptor 5WS3
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
TM5 188 5.30x31 CCR5 5UIW - -
TM5 189 5.31x32 CCR5 5UIW apelin receptor 5VBL
TM5 190 5.32x33 CCR5 5UIW NTS1 receptor 4BUO
TM5 191 5.33x34 CCR5 5UIW - -
TM5 192 5.34x35 CCR5 5UIW P2Y1 receptor 4XNW
TM5 193 5.35x36 CCR5 5UIW NTS1 receptor 4BUO
TM5 194 5.36x37 CCR5 5UIW NOP receptor 5DHG
TM5 195 5.37x38 CCR5 5UIW H1 receptor 3RZE
TM5 196 5.38x39 CCR5 5UIW M3 receptor 4U15
TM5 197 5.39x40 CCR5 5UIW BLT1 receptor 5X33
TM5 198 5.40x41 CCR5 5UIW CCR5 5UIW
TM5 199 5.41x42 CCR5 5UIW M3 receptor 4U15
TM5 200 5.42x43 CCR5 5UIW - -
TM5 201 5.43x44 CCR5 5UIW - -
TM5 202 5.44x45 CCR5 5UIW BLT1 receptor 5X33
TM5 203 5.45x46 CCR5 5UIW H1 receptor 3RZE
TM5 204 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 205 5.47x47 CCR5 5UIW OX2 receptor 5WS3
TM5 206 5.48x48 CCR5 5UIW CCR5 5UIW
TM5 207 5.49x49 CCR5 5UIW CCR5 5UIW
TM5 208 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 209 5.51x51 CCR5 5UIW CCR5 5UIW
TM5 210 5.52x52 CCR5 5UIW CXCR4 3ODU
TM5 211 5.53x53 CCR5 5UIW AT1 receptor 4ZUD
TM5 212 5.54x54 CCR5 5UIW AT1 receptor 4ZUD
TM5 213 5.55x55 CCR5 5UIW AT1 receptor 4ZUD
TM5 214 5.56x56 CCR5 5UIW CCR5 5UIW
TM5 215 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 216 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 217 5.59x59 CCR5 5UIW CCR5 5UIW
TM5 218 5.60x60 CCR5 5UIW OX2 receptor 5WS3
TM5 219 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 220 5.62x62 CCR5 5UIW - -
TM5 221 5.63x63 CCR5 5UIW ETB receptor 5X93
TM5 222 5.64x64 CCR5 5UIW CXCR4 3ODU
TM5 223 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 224 5.66x66 CCR5 5UIW - -
TM5 225 5.67x67 CCR5 5UIW - -
TM5 226 5.68x68 κ receptor 4DJH AT2 receptor 5UNH
ICL3 227 - - - -
ICL3 228 μ receptor 5C1M - -
ICL3 229 μ receptor 5C1M - -
ICL3 230 μ receptor 5C1M - -
ICL3 231 - - - -
TM6 232 6.23x23 κ receptor 6B73 - -
TM6 233 6.24x24 κ receptor 6B73 - -
TM6 234 6.25x25 κ receptor 6B73 NOP receptor 5DHG
TM6 235 6.26x26 κ receptor 6B73 NOP receptor 5DHG
TM6 236 6.27x27 κ receptor 6B73 Y1 receptor 5ZBH
TM6 237 6.28x28 CCR5 5UIW A1 receptor 5N2S
TM6 238 6.29x29 CCR5 5UIW - -
TM6 239 6.30x30 CCR5 5UIW S1P1 receptor 3V2Y
TM6 240 6.31x31 CCR5 5UIW M3 receptor 4U15
TM6 241 6.32x32 CCR5 5UIW CXCR4 3ODU
TM6 242 6.33x33 CCR5 5UIW CCR2 5T1A
TM6 243 6.34x34 CCR5 5UIW CXCR4 3ODU
TM6 244 6.35x35 CCR5 5UIW - -
TM6 245 6.36x36 CCR5 5UIW CXCR4 3ODU
TM6 246 6.37x37 CCR5 5UIW CCR5 5UIW
TM6 247 6.38x38 CCR5 5UIW CCR9 5LWE
TM6 248 6.39x39 CCR5 5UIW A1 receptor 5UEN
TM6 249 6.40x40 CCR5 5UIW CCR5 5UIW
TM6 250 6.41x41 CCR5 5UIW CXCR4 3ODU
TM6 251 6.42x42 CCR5 5UIW apelin receptor 5VBL
TM6 252 6.43x43 CCR5 5UIW CCR5 5UIW
TM6 253 6.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM6 254 6.45x45 CCR5 5UIW κ receptor 4DJH
TM6 255 6.46x46 CCR5 5UIW CCR5 5UIW
TM6 256 6.47x47 CCR5 5UIW κ receptor 4DJH
TM6 257 6.48x48 CCR5 5UIW LPA6 receptor 5XSZ
TM6 258 6.49x49 CCR5 5UIW κ receptor 4DJH
TM6 259 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 260 6.51x51 CCR5 5UIW CCR5 5UIW
TM6 261 6.52x52 CCR5 5UIW κ receptor 4DJH
TM6 262 6.53x53 CCR5 5UIW NOP receptor 5DHG
TM6 263 6.54x54 CCR5 5UIW ETB receptor 5X93
TM6 264 6.55x55 CCR5 5UIW κ receptor 4DJH
TM6 265 6.56x56 CCR5 5UIW μ receptor 4DKL
TM6 266 6.57x57 CCR5 5UIW - -
TM6 267 6.58x58 CCR5 5UIW β2-adrenoceptor 5JQH
TM6 268 6.59x59 CCR5 5UIW apelin receptor 5VBL
TM6 269 6.60x60 CCR5 5UIW CCR9 5LWE
TM6 270 6.61x61 CCR5 5UIW US28 4XT1
TM6 271 6.62x62 LPA6 receptor 5XSZ - -
TM6 272 6.63x63 LPA6 receptor 5XSZ AT1 receptor 4YAY
TM6 273 6.64x64 LPA6 receptor 5XSZ - -
ECL3 274 - - - -
ECL3 275 P2Y1 receptor 4XNW - -
ECL3 276 P2Y1 receptor 4XNW - -
ECL3 277 P2Y1 receptor 4XNW - -
ECL3 278 - - - -
TM7 279 7.24x23 CCR5 5UIW - -
TM7 280 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 281 7.26x25 CCR5 5UIW CCR5 5UIW
TM7 282 7.27x26 CCR5 5UIW - -
TM7 283 7.28x27 CCR5 5UIW OX2 receptor 5WS3
TM7 284 7.29x28 CCR5 5UIW - -
TM7 285 7.30x29 CCR5 5UIW US28 4XT1
TM7 286 7.31x30 CCR5 5UIW - -
TM7 287 7.32x31 CCR5 5UIW 5-HT2B receptor 4IB4
TM7 288 7.33x32 CCR5 5UIW CCR9 5LWE
TM7 289 7.34x33 CCR5 5UIW κ receptor 4DJH
TM7 290 7.35x34 CCR5 5UIW δ receptor 4N6H
TM7 291 7.36x35 CCR5 5UIW μ receptor 4DKL
TM7 292 7.37x36 CCR5 5UIW κ receptor 4DJH
TM7 293 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 294 7.39x38 CCR5 5UIW 5-HT2C receptor 6BQH
TM7 295 7.40x39 CCR5 5UIW AT1 receptor 4ZUD
TM7 296 7.41x40 CCR5 5UIW CCR5 5UIW
TM7 297 7.42x41 CCR5 5UIW - -
TM7 298 7.43x42 CCR5 5UIW - -
TM7 299 7.44x43 CCR5 5UIW AT1 receptor 4ZUD
TM7 300 7.45x45 CCR5 5UIW AT1 receptor 4ZUD
TM7 301 7.46x46 CCR5 5UIW CCR5 5UIW
TM7 302 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 303 7.48x48 CCR5 5UIW A1 receptor 5UEN
TM7 304 7.49x49 CCR5 5UIW LPA6 receptor 5XSZ
TM7 305 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 306 7.51x51 CCR5 5UIW apelin receptor 5VBL
TM7 307 7.52x52 CCR5 5UIW CCR5 5UIW
TM7 308 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 309 7.54x54 CCR5 5UIW P2Y12 receptor 4NTJ
TM7 310 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 311 7.56x56 CCR5 5UIW C5a1 receptor 5O9H
H8 312 8.47x47 CCR5 5UIW P2Y12 receptor 4NTJ
H8 313 8.48x48 CCR5 5UIW 5-HT2C receptor 6BQH
H8 314 8.49x49 CCR5 5UIW - -
H8 315 8.50x50 CCR5 5UIW 5-HT2C receptor 6BQH
H8 316 8.51x51 CCR5 5UIW κ receptor 4DJH
H8 317 8.52x52 CCR5 5UIW κ receptor 4DJH
H8 318 8.53x53 CCR5 5UIW AT2 receptor 5UNG
H8 319 8.54x54 CCR5 5UIW - -
H8 320 8.55x55 CCR5 5UIW - -
H8 321 8.56x56 CCR5 5UIW 5-HT2B receptor 4IB4
H8 322 8.57x57 CCR5 5UIW apelin receptor 5VBL
H8 323 8.58x58 CCR5 5UIW apelin receptor 5VBL
H8 324 8.59x59 CCR5 5UIW CCR9 5LWE
C-term 325 - - - -
C-term 326 - - - -
C-term 327 - - - -
C-term 328 - - - -
C-term 329 - - - -