GPR15 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 7.21 docs)

VERSION

2018-07-10

MAIN TEMPLATE

AT2 receptor (sequence similarity: 49%) PDB: 5UNG

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.1 18.5 6.4
Side-chains 25.6 50.2 24.2

Number of backbone templates: 8
Number of rotamer templates: 39

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5UNG
5UNF
4ZUD
4YAY
5VBL
4N6H
5UIW
4XES
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 29 AT2 receptor 5UNG AT2 receptor 5UNG
N-term 30 AT2 receptor 5UNG AT2 receptor 5UNG
N-term 31 AT2 receptor 5UNG AT2 receptor 5UNG
N-term 32 AT2 receptor 5UNG AT2 receptor 5UNG
N-term 33 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 34 1.33x33 AT2 receptor 5UNG - -
TM1 35 1.34x34 AT2 receptor 5UNG M2 receptor 4MQT
TM1 36 1.35x35 AT2 receptor 5UNG 5-HT1B receptor 6G79
TM1 37 1.36x36 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 38 1.37x37 AT2 receptor 5UNG CB1 receptor 5XRA
TM1 39 1.38x38 AT2 receptor 5UNG - -
TM1 40 1.39x39 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 41 1.40x40 AT2 receptor 5UNG PAR1 3VW7
TM1 42 1.41x41 AT2 receptor 5UNG NTS1 receptor 5T04
TM1 43 1.42x42 AT2 receptor 5UNG μ receptor 5C1M
TM1 44 1.43x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 45 1.44x44 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM1 46 1.45x45 AT2 receptor 5UNG CXCR4 3ODU
TM1 47 1.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 48 1.47x47 AT2 receptor 5UNG PAF receptor 5ZKP
TM1 49 1.48x48 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 50 1.49x49 AT2 receptor 5UNG μ receptor 5C1M
TM1 51 1.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 52 1.51x51 AT2 receptor 5UNG CB1 receptor 5XRA
TM1 53 1.52x52 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 54 1.53x53 AT2 receptor 5UNG Y1 receptor 5ZBH
TM1 55 1.54x54 AT2 receptor 5UNG μ receptor 5C1M
TM1 56 1.55x55 AT2 receptor 5UNG - -
TM1 57 1.56x56 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM1 58 1.57x57 AT2 receptor 5UNG CCR5 5UIW
TM1 59 1.58x58 AT2 receptor 5UNG - -
TM1 60 1.59x59 AT2 receptor 5UNG AT1 receptor 4YAY
TM1 61 1.60x60 AT2 receptor 5UNF PAR1 3VW7
ICL1 62 - - - -
ICL1 63 AT1 receptor 4ZUD - -
ICL1 64 AT1 receptor 4ZUD - -
ICL1 65 - - - -
TM2 66 2.37x37 AT1 receptor 4ZUD apelin receptor 5VBL
TM2 67 2.38x38 AT2 receptor 5UNG CCR2 5T1A
TM2 68 2.39x39 AT2 receptor 5UNG PAF receptor 5ZKP
TM2 69 2.40x40 AT2 receptor 5UNG US28 4XT1
TM2 70 2.41x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 71 2.42x42 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM2 72 2.43x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 73 2.44x44 AT2 receptor 5UNG US28 4XT1
TM2 74 2.45x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 75 2.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 76 2.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 77 2.48x48 AT2 receptor 5UNG US28 4XT1
TM2 78 2.49x49 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM2 79 2.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 80 2.51x51 AT2 receptor 5UNG P2Y1 receptor 4XNW
TM2 81 2.52x52 AT2 receptor 5UNG M2 receptor 4MQT
TM2 82 2.53x53 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM2 83 2.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 84 2.55x55 AT2 receptor 5UNG M2 receptor 4MQT
TM2 85 2.56x56 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 86 2.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 87 2.58x58 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 88 2.59x59 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 89 2.60x60 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 90 2.61x61 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM2 91 2.62x62 AT2 receptor 5UNG - -
TM2 92 2.63x63 AT2 receptor 5UNG δ receptor 4N6H
TM2 93 2.64x64 AT2 receptor 5UNG D4 receptor 5WIV
TM2 94 2.65x65 AT2 receptor 5UNG AT1 receptor 4ZUD
TM2 95 2.66x66 AT2 receptor 5UNG PAR1 3VW7
TM2 96 2.67x67 apelin receptor 5VBL - -
ECL1 97 - - - -
ECL1 98 23.49x49 AT2 receptor 5UNF - -
ECL1 99 23.50x50 AT2 receptor 5UNF AT2 receptor 5UNF
ECL1 100 23.51x51 AT2 receptor 5UNF LPA1 receptor 4Z35
ECL1 101 23.52x52 AT2 receptor 5UNF AT2 receptor 5UNF
TM3 102 3.21x21 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 103 3.22x22 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 104 3.23x23 AT2 receptor 5UNG PAF receptor 5ZKP
TM3 105 3.24x24 AT2 receptor 5UNG μ receptor 5C1M
TM3 106 3.25x25 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 107 3.26x26 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 108 3.27x27 AT2 receptor 5UNG NTS1 receptor 5T04
TM3 109 3.28x28 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 110 3.29x29 AT2 receptor 5UNG AT1 receptor 4ZUD
TM3 111 3.30x30 AT2 receptor 5UNG apelin receptor 5VBL
TM3 112 3.31x31 AT2 receptor 5UNG CCR9 5LWE
TM3 113 3.32x32 AT2 receptor 5UNG apelin receptor 5VBL
TM3 114 3.33x33 AT2 receptor 5UNG AT1 receptor 4ZUD
TM3 115 3.34x34 AT2 receptor 5UNG M2 receptor 4MQT
TM3 116 3.35x35 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 117 3.36x36 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 118 3.37x37 AT2 receptor 5UNG - -
TM3 119 3.38x38 AT2 receptor 5UNG PAF receptor 5ZKP
TM3 120 3.39x39 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 121 3.40x40 AT2 receptor 5UNG PAF receptor 5ZKP
TM3 122 3.41x41 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 123 3.42x42 AT2 receptor 5UNG AT1 receptor 4ZUD
TM3 124 3.43x43 AT2 receptor 5UNG μ receptor 5C1M
TM3 125 3.44x44 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 126 3.45x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 127 3.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 128 3.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 129 3.48x48 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 130 3.49x49 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 131 3.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 132 3.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 133 3.52x52 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 134 3.53x53 AT2 receptor 5UNG μ receptor 5C1M
TM3 135 3.54x54 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 136 3.55x55 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 137 3.56x56 AT2 receptor 5UNG - -
ICL2 138 34.50x50 - - - -
ICL2 139 34.51x51 δ receptor 4N6H μ receptor 5C1M
ICL2 140 34.52x52 δ receptor 4N6H - -
ICL2 141 34.53x53 δ receptor 4N6H LPA6 receptor 5XSZ
ICL2 142 34.54x54 δ receptor 4N6H LPA6 receptor 5XSZ
ICL2 143 34.55x55 δ receptor 4N6H BLT1 receptor 5X33
ICL2 144 34.56x56 δ receptor 4N6H δ receptor 4N6H
ICL2 145 34.57x57 - - - -
TM4 146 4.38x38 AT1 receptor 4YAY CCR9 5LWE
TM4 147 4.39x39 AT1 receptor 4YAY M2 receptor 4MQT
TM4 148 4.40x40 AT1 receptor 4YAY - -
TM4 149 4.41x41 AT2 receptor 5UNG - -
TM4 150 4.42x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 151 4.43x43 AT2 receptor 5UNG Y1 receptor 5ZBH
TM4 152 4.44x44 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM4 153 4.45x45 AT2 receptor 5UNG μ receptor 5C1M
TM4 154 4.46x46 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 155 4.47x47 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 156 4.48x48 AT2 receptor 5UNG - -
TM4 157 4.49x49 AT2 receptor 5UNG κ receptor 6B73
TM4 158 4.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 159 4.51x51 AT2 receptor 5UNG H1 receptor 3RZE
TM4 160 4.52x52 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM4 161 4.53x53 AT2 receptor 5UNG μ receptor 5C1M
TM4 162 4.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 163 4.55x55 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 164 4.56x56 AT2 receptor 5UNG M2 receptor 4MQT
TM4 165 4.57x57 δ receptor 4N6H δ receptor 4N6H
TM4 166 4.58x58 δ receptor 4N6H μ receptor 5C1M
TM4 167 4.59x59 δ receptor 4N6H δ receptor 4N6H
TM4 168 4.60x60 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 169 4.61x61 AT2 receptor 5UNG PAF receptor 5ZKP
TM4 170 4.62x62 AT2 receptor 5UNG M2 receptor 4MQT
TM4 171 4.63x63 AT2 receptor 5UNG - -
TM4 172 4.64x64 AT2 receptor 5UNG - -
ECL2 173 - - - -
ECL2 174 CCR5 5UIW - -
ECL2 175 CCR5 5UIW - -
ECL2 176 CCR5 5UIW - -
ECL2 177 CCR5 5UIW - -
ECL2 178 CCR5 5UIW - -
ECL2 179 CCR5 5UIW - -
ECL2 180 CCR5 5UIW - -
ECL2 181 CCR5 5UIW - -
ECL2 182 - - - -
ECL2 183 45.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
ECL2 184 45.51x51 AT2 receptor 5UNG AT1 receptor 4ZUD
ECL2 185 45.52x52 AT2 receptor 5UNG OX2 receptor 5WS3
ECL2 186 - - - -
TM5 187 5.30x31 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 188 5.31x32 AT2 receptor 5UNG - -
TM5 189 5.32x33 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 190 5.33x34 AT2 receptor 5UNG - -
TM5 191 5.34x35 AT2 receptor 5UNG - -
TM5 192 5.35x36 AT2 receptor 5UNG CCR5 5UIW
TM5 193 5.36x37 AT2 receptor 5UNG κ receptor 6B73
TM5 194 5.37x38 AT2 receptor 5UNG PAF receptor 5ZKP
TM5 195 5.38x39 AT2 receptor 5UNG - -
TM5 196 5.39x40 AT2 receptor 5UNG P2Y1 receptor 4XNW
TM5 197 5.40x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 198 5.41x42 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 199 5.42x43 AT2 receptor 5UNG - -
TM5 200 5.43x44 AT2 receptor 5UNG C5a1 receptor 5O9H
TM5 201 5.44x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 202 5.45x46 AT2 receptor 5UNG μ receptor 5C1M
TM5 203 5.46x461 AT2 receptor 5UNG OX2 receptor 5WS3
TM5 204 5.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 205 5.48x48 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM5 206 5.49x49 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM5 207 5.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 208 5.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 209 5.52x52 AT2 receptor 5UNG μ receptor 5C1M
TM5 210 5.53x53 AT2 receptor 5UNG S1P1 receptor 3V2Y
TM5 211 5.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 212 5.55x55 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM5 213 5.56x56 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 214 5.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 215 5.58x58 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 216 5.59x59 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM5 217 5.60x60 AT2 receptor 5UNG - -
TM5 218 5.61x61 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 219 5.62x62 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 220 5.63x63 AT2 receptor 5UNG PAF receptor 5ZKP
TM5 221 5.64x64 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 222 5.65x65 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 223 5.66x66 AT2 receptor 5UNG - -
TM5 224 5.67x67 AT2 receptor 5UNG - -
TM5 225 5.68x68 AT2 receptor 5UNG CB1 receptor 5XRA
ICL3 226 - - - -
ICL3 227 - - - -
ICL3 228 - - - -
ICL3 229 - - - -
TM6 230 6.24x24 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 231 6.25x25 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 232 6.26x26 AT2 receptor 5UNG ETB receptor 5X93
TM6 233 6.27x27 AT2 receptor 5UNG PAR1 3VW7
TM6 234 6.28x28 AT2 receptor 5UNG Rhodopsin 5DYS
TM6 235 6.29x29 AT2 receptor 5UNG β2-adrenoceptor 4LDE
TM6 236 6.30x30 AT2 receptor 5UNG μ receptor 5C1M
TM6 237 6.31x31 AT2 receptor 5UNG PAF receptor 5ZKP
TM6 238 6.32x32 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM6 239 6.33x33 AT2 receptor 5UNG - -
TM6 240 6.34x34 AT2 receptor 5UNG - -
TM6 241 6.35x35 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 242 6.36x36 AT2 receptor 5UNG AT1 receptor 4ZUD
TM6 243 6.37x37 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM6 244 6.38x38 AT2 receptor 5UNG CCR5 5UIW
TM6 245 6.39x39 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM6 246 6.40x40 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 247 6.41x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 248 6.42x42 AT2 receptor 5UNG μ receptor 5C1M
TM6 249 6.43x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 250 6.44x44 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 251 6.45x45 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM6 252 6.46x46 AT2 receptor 5UNG μ receptor 5C1M
TM6 253 6.47x47 AT2 receptor 5UNG A1 receptor 6D9H
TM6 254 6.48x48 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 255 6.49x49 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 256 6.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 257 6.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 258 6.52x52 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM6 259 6.53x53 AT2 receptor 5UNG - -
TM6 260 6.54x54 AT2 receptor 5UNG κ receptor 6B73
TM6 261 6.55x55 AT2 receptor 5UNG apelin receptor 5VBL
TM6 262 6.56x56 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 263 6.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 264 6.58x58 AT2 receptor 5UNG - -
TM6 265 6.59x59 AT2 receptor 5UNG D2 receptor 6CM4
TM6 266 6.60x60 AT2 receptor 5UNG OX2 receptor 5WS3
TM6 267 6.61x61 AT2 receptor 5UNG P2Y12 receptor 4PXZ
ECL3 268 - - - -
ECL3 269 NTS1 receptor 4XES - -
ECL3 270 NTS1 receptor 4XES - -
ECL3 271 NTS1 receptor 4XES NTS1 receptor 4XES
ECL3 272 - - - -
TM7 273 7.24x23 AT2 receptor 5UNG - -
TM7 274 7.25x24 AT2 receptor 5UNG - -
TM7 275 7.26x25 AT2 receptor 5UNG - -
TM7 276 7.27x26 AT2 receptor 5UNG - -
TM7 277 7.28x27 AT2 receptor 5UNG CCR9 5LWE
TM7 278 7.29x28 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 279 7.30x29 AT2 receptor 5UNG AT1 receptor 4ZUD
TM7 280 7.31x30 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM7 281 7.32x31 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM7 282 7.33x32 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 283 7.34x33 AT2 receptor 5UNG - -
TM7 284 7.35x34 AT2 receptor 5UNG Rhodopsin 5DYS
TM7 285 7.36x35 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM7 286 7.37x36 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM7 287 7.38x37 AT2 receptor 5UNG OX2 receptor 5WS3
TM7 288 7.39x38 AT2 receptor 5UNG - -
TM7 289 7.40x39 AT2 receptor 5UNG - -
TM7 290 7.41x40 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 291 7.42x41 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM7 292 7.43x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 293 7.44x43 AT2 receptor 5UNG NTS1 receptor 5T04
TM7 294 7.45x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 295 7.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 296 7.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 297 7.48x48 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 298 7.49x49 apelin receptor 5VBL apelin receptor 5VBL
TM7 299 7.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM7 300 7.51x51 apelin receptor 5VBL apelin receptor 5VBL
TM7 301 7.52x52 apelin receptor 5VBL PAF receptor 5ZKP
TM7 302 7.53x53 apelin receptor 5VBL apelin receptor 5VBL
TM7 303 7.54x54 apelin receptor 5VBL LPA6 receptor 5XSZ
TM7 304 7.55x55 apelin receptor 5VBL - -
TM7 305 7.56x56 apelin receptor 5VBL apelin receptor 5VBL
H8 306 8.47x47 apelin receptor 5VBL apelin receptor 5VBL
H8 307 8.48x48 apelin receptor 5VBL - -
H8 308 8.49x49 apelin receptor 5VBL - -
H8 309 8.50x50 apelin receptor 5VBL - -
H8 310 8.51x51 apelin receptor 5VBL 5-HT2C receptor 6BQG
H8 311 8.52x52 apelin receptor 5VBL 5-HT2C receptor 6BQG
H8 312 8.53x53 apelin receptor 5VBL 5-HT2C receptor 6BQG
H8 313 8.54x54 apelin receptor 5VBL - -
H8 314 8.55x55 apelin receptor 5VBL Rhodopsin 5DYS
H8 315 8.56x56 apelin receptor 5VBL M2 receptor 4MQT
H8 316 8.57x57 apelin receptor 5VBL - -
H8 317 8.58x58 apelin receptor 5VBL 5-HT2C receptor 6BQG
H8 318 8.59x59 apelin receptor 5VBL β2-adrenoceptor 3SN6
H8 319 8.60x60 apelin receptor 5VBL - -
H8 320 8.61x61 apelin receptor 5VBL OX2 receptor 5WS3
C-term 321 - - - -
C-term 322 - - - -
C-term 323 - - - -
C-term 324 - - - -
C-term 325 - - - -