GPR17 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -0.58 docs)

VERSION

2018-07-10

MAIN TEMPLATE

apelin receptor (sequence similarity: 51%) PDB: 5VBL

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 88.1 7.8 4.1
Side-chains 30.6 50.0 19.4

Number of backbone templates: 4
Number of rotamer templates: 35

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5VBL
5XSZ
5UIW
5UNG
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 55 apelin receptor 5VBL apelin receptor 5VBL
N-term 56 apelin receptor 5VBL apelin receptor 5VBL
N-term 57 apelin receptor 5VBL apelin receptor 5VBL
N-term 58 apelin receptor 5VBL apelin receptor 5VBL
N-term 59 apelin receptor 5VBL apelin receptor 5VBL
TM1 60 1.33x33 apelin receptor 5VBL - -
TM1 61 1.34x34 apelin receptor 5VBL apelin receptor 5VBL
TM1 62 1.35x35 apelin receptor 5VBL PAF receptor 5ZKP
TM1 63 1.36x36 apelin receptor 5VBL Rhodopsin 1GZM
TM1 64 1.37x37 apelin receptor 5VBL PAR1 3VW7
TM1 65 1.38x38 apelin receptor 5VBL - -
TM1 66 1.39x39 apelin receptor 5VBL apelin receptor 5VBL
TM1 67 1.40x40 apelin receptor 5VBL NOP receptor 5DHG
TM1 68 1.41x41 apelin receptor 5VBL apelin receptor 5VBL
TM1 69 1.42x42 apelin receptor 5VBL - -
TM1 70 1.43x43 apelin receptor 5VBL apelin receptor 5VBL
TM1 71 1.44x44 apelin receptor 5VBL CCR5 5UIW
TM1 72 1.45x45 apelin receptor 5VBL apelin receptor 5VBL
TM1 73 1.46x46 apelin receptor 5VBL OX2 receptor 5WS3
TM1 74 1.47x47 apelin receptor 5VBL κ receptor 4DJH
TM1 75 1.48x48 apelin receptor 5VBL κ receptor 4DJH
TM1 76 1.49x49 apelin receptor 5VBL apelin receptor 5VBL
TM1 77 1.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM1 78 1.51x51 apelin receptor 5VBL BLT1 receptor 5X33
TM1 79 1.52x52 apelin receptor 5VBL apelin receptor 5VBL
TM1 80 1.53x53 apelin receptor 5VBL LPA6 receptor 5XSZ
TM1 81 1.54x54 apelin receptor 5VBL apelin receptor 5VBL
TM1 82 1.55x55 apelin receptor 5VBL apelin receptor 5VBL
TM1 83 1.56x56 apelin receptor 5VBL AT2 receptor 5UNG
TM1 84 1.57x57 apelin receptor 5VBL M3 receptor 4U15
TM1 85 1.58x58 apelin receptor 5VBL CCR5 5UIW
TM1 86 1.59x59 apelin receptor 5VBL apelin receptor 5VBL
TM1 87 1.60x60 apelin receptor 5VBL - -
ICL1 88 - - - -
ICL1 89 LPA6 receptor 5XSZ - -
ICL1 90 LPA6 receptor 5XSZ - -
ICL1 91 - - - -
TM2 92 2.37x37 apelin receptor 5VBL AT1 receptor 4ZUD
TM2 93 2.38x38 apelin receptor 5VBL Rhodopsin 1GZM
TM2 94 2.39x39 apelin receptor 5VBL apelin receptor 5VBL
TM2 95 2.40x40 apelin receptor 5VBL κ receptor 4DJH
TM2 96 2.41x41 apelin receptor 5VBL AT1 receptor 4ZUD
TM2 97 2.42x42 apelin receptor 5VBL apelin receptor 5VBL
TM2 98 2.43x43 apelin receptor 5VBL AT1 receptor 4ZUD
TM2 99 2.44x44 apelin receptor 5VBL 5-HT2C receptor 6BQH
TM2 100 2.45x45 apelin receptor 5VBL CXCR4 3ODU
TM2 101 2.46x46 apelin receptor 5VBL apelin receptor 5VBL
TM2 102 2.47x47 apelin receptor 5VBL apelin receptor 5VBL
TM2 103 2.48x48 apelin receptor 5VBL apelin receptor 5VBL
TM2 104 2.49x49 apelin receptor 5VBL apelin receptor 5VBL
TM2 105 2.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM2 106 2.51x51 apelin receptor 5VBL apelin receptor 5VBL
TM2 107 2.52x52 apelin receptor 5VBL - -
TM2 108 2.53x53 apelin receptor 5VBL - -
TM2 109 2.54x54 apelin receptor 5VBL apelin receptor 5VBL
TM2 110 2.55x55 apelin receptor 5VBL AT1 receptor 4ZUD
TM2 111 2.56x56 apelin receptor 5VBL D2 receptor 6CM4
TM2 112 2.57x57 apelin receptor 5VBL apelin receptor 5VBL
TM2 113 2.58x58 apelin receptor 5VBL apelin receptor 5VBL
TM2 114 2.59x59 apelin receptor 5VBL Rhodopsin 1GZM
TM2 115 2.60x60 apelin receptor 5VBL LPA6 receptor 5XSZ
TM2 116 2.61x61 apelin receptor 5VBL OX2 receptor 5WS3
TM2 117 2.62x62 apelin receptor 5VBL AT1 receptor 4ZUD
TM2 118 2.63x63 apelin receptor 5VBL apelin receptor 5VBL
TM2 119 2.64x64 apelin receptor 5VBL PAR2 5NDD
TM2 120 2.65x65 apelin receptor 5VBL P2Y1 receptor 4XNW
TM2 121 2.66x66 apelin receptor 5VBL PAR1 3VW7
TM2 122 2.67x67 apelin receptor 5VBL BLT1 receptor 5X33
ECL1 123 apelin receptor 5VBL - -
ECL1 124 23.49x49 apelin receptor 5VBL C5a1 receptor 5O9H
ECL1 125 23.50x50 apelin receptor 5VBL apelin receptor 5VBL
ECL1 126 23.51x51 apelin receptor 5VBL apelin receptor 5VBL
ECL1 127 23.52x52 apelin receptor 5VBL apelin receptor 5VBL
TM3 128 3.21x21 apelin receptor 5VBL apelin receptor 5VBL
TM3 129 3.22x22 apelin receptor 5VBL δ receptor 4N6H
TM3 130 3.23x23 apelin receptor 5VBL μ receptor 4DKL
TM3 131 3.24x24 apelin receptor 5VBL C5a1 receptor 5O9H
TM3 132 3.25x25 apelin receptor 5VBL apelin receptor 5VBL
TM3 133 3.26x26 apelin receptor 5VBL BLT1 receptor 5X33
TM3 134 3.27x27 apelin receptor 5VBL apelin receptor 5VBL
TM3 135 3.28x28 apelin receptor 5VBL P2Y12 receptor 4NTJ
TM3 136 3.29x29 apelin receptor 5VBL Rhodopsin 1GZM
TM3 137 3.30x30 apelin receptor 5VBL ETB receptor 5X93
TM3 138 3.31x31 apelin receptor 5VBL apelin receptor 5VBL
TM3 139 3.32x32 apelin receptor 5VBL LPA6 receptor 5XSZ
TM3 140 3.33x33 apelin receptor 5VBL κ receptor 4DJH
TM3 141 3.34x34 apelin receptor 5VBL C5a1 receptor 5O9H
TM3 142 3.35x35 apelin receptor 5VBL apelin receptor 5VBL
TM3 143 3.36x36 apelin receptor 5VBL apelin receptor 5VBL
TM3 144 3.37x37 apelin receptor 5VBL apelin receptor 5VBL
TM3 145 3.38x38 apelin receptor 5VBL apelin receptor 5VBL
TM3 146 3.39x39 apelin receptor 5VBL apelin receptor 5VBL
TM3 147 3.40x40 apelin receptor 5VBL κ receptor 4DJH
TM3 148 3.41x41 apelin receptor 5VBL - -
TM3 149 3.42x42 apelin receptor 5VBL CCR5 5UIW
TM3 150 3.43x43 apelin receptor 5VBL apelin receptor 5VBL
TM3 151 3.44x44 apelin receptor 5VBL apelin receptor 5VBL
TM3 152 3.45x45 apelin receptor 5VBL AT1 receptor 4ZUD
TM3 153 3.46x46 apelin receptor 5VBL CCR9 5LWE
TM3 154 3.47x47 apelin receptor 5VBL apelin receptor 5VBL
TM3 155 3.48x48 apelin receptor 5VBL C5a1 receptor 5O9H
TM3 156 3.49x49 apelin receptor 5VBL apelin receptor 5VBL
TM3 157 3.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM3 158 3.51x51 apelin receptor 5VBL C5a1 receptor 5O9H
TM3 159 3.52x52 apelin receptor 5VBL apelin receptor 5VBL
TM3 160 3.53x53 apelin receptor 5VBL apelin receptor 5VBL
TM3 161 3.54x54 apelin receptor 5VBL apelin receptor 5VBL
TM3 162 3.55x55 apelin receptor 5VBL apelin receptor 5VBL
TM3 163 3.56x56 apelin receptor 5VBL AT1 receptor 4ZUD
ICL2 164 34.50x50 - - - -
ICL2 165 34.51x51 LPA6 receptor 5XSZ CCR5 4MBS
ICL2 166 34.52x52 LPA6 receptor 5XSZ δ receptor 4N6H
ICL2 167 34.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 168 34.54x54 LPA6 receptor 5XSZ CCR5 4MBS
ICL2 169 34.55x55 LPA6 receptor 5XSZ BLT1 receptor 5X33
ICL2 170 34.56x56 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 171 34.57x57 - - - -
TM4 172 4.38x38 apelin receptor 5VBL CCR9 5LWE
TM4 173 4.39x39 apelin receptor 5VBL κ receptor 4DJH
TM4 174 4.40x40 apelin receptor 5VBL AT1 receptor 4ZUD
TM4 175 4.41x41 apelin receptor 5VBL CCR9 5LWE
TM4 176 4.42x42 apelin receptor 5VBL AT1 receptor 4ZUD
TM4 177 4.43x43 apelin receptor 5VBL - -
TM4 178 4.44x44 apelin receptor 5VBL δ receptor 4N6H
TM4 179 4.45x45 apelin receptor 5VBL apelin receptor 5VBL
TM4 180 4.46x46 apelin receptor 5VBL AT1 receptor 4ZUD
TM4 181 4.47x47 apelin receptor 5VBL apelin receptor 5VBL
TM4 182 4.48x48 apelin receptor 5VBL Rhodopsin 1GZM
TM4 183 4.49x49 apelin receptor 5VBL apelin receptor 5VBL
TM4 184 4.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM4 185 4.51x51 apelin receptor 5VBL apelin receptor 5VBL
TM4 186 4.52x52 apelin receptor 5VBL CCR5 5UIW
TM4 187 4.53x53 apelin receptor 5VBL LPA6 receptor 5XSZ
TM4 188 4.54x54 apelin receptor 5VBL apelin receptor 5VBL
TM4 189 4.55x55 apelin receptor 5VBL NOP receptor 5DHG
TM4 190 4.56x56 apelin receptor 5VBL AT1 receptor 4ZUD
TM4 191 4.57x57 apelin receptor 5VBL OX2 receptor 5WS3
TM4 192 4.58x59 apelin receptor 5VBL D4 receptor 5WIV
TM4 193 4.59x60 apelin receptor 5VBL apelin receptor 5VBL
TM4 194 4.60x61 apelin receptor 5VBL Rhodopsin 1GZM
TM4 195 4.61x62 apelin receptor 5VBL BLT1 receptor 5X33
TM4 196 4.62x63 apelin receptor 5VBL apelin receptor 5VBL
TM4 197 4.63x64 apelin receptor 5VBL - -
TM4 198 4.64x65 apelin receptor 5VBL - -
ECL2 199 - - - -
ECL2 200 CCR5 5UIW - -
ECL2 201 CCR5 5UIW - -
ECL2 202 CCR5 5UIW - -
ECL2 203 CCR5 5UIW - -
ECL2 204 CCR5 5UIW - -
ECL2 205 CCR5 5UIW - -
ECL2 206 CCR5 5UIW - -
ECL2 207 CCR5 5UIW - -
ECL2 208 - - - -
ECL2 209 45.50x50 apelin receptor 5VBL apelin receptor 5VBL
ECL2 210 45.51x51 apelin receptor 5VBL NOP receptor 5DHG
ECL2 211 45.52x52 apelin receptor 5VBL - -
TM5 212 5.30x31 apelin receptor 5VBL - -
TM5 213 5.31x32 apelin receptor 5VBL κ receptor 4DJH
TM5 214 5.32x33 apelin receptor 5VBL - -
TM5 215 5.33x34 apelin receptor 5VBL - -
TM5 216 5.34x35 apelin receptor 5VBL - -
TM5 217 5.35x36 apelin receptor 5VBL ETB receptor 5X93
TM5 218 5.36x37 apelin receptor 5VBL LPA6 receptor 5XSZ
TM5 219 5.37x38 apelin receptor 5VBL S1P1 receptor 3V2Y
TM5 220 5.38x39 apelin receptor 5VBL CCR2 5T1A
TM5 221 5.39x40 apelin receptor 5VBL C5a1 receptor 5O9H
TM5 222 5.40x41 apelin receptor 5VBL AT1 receptor 4ZUD
TM5 223 5.41x42 apelin receptor 5VBL C5a1 receptor 5O9H
TM5 224 5.42x43 apelin receptor 5VBL apelin receptor 5VBL
TM5 225 5.43x44 apelin receptor 5VBL C5a1 receptor 5O9H
TM5 226 5.44x45 apelin receptor 5VBL - -
TM5 227 5.45x46 apelin receptor 5VBL apelin receptor 5VBL
TM5 228 5.46x461 apelin receptor 5VBL κ receptor 4DJH
TM5 229 5.47x47 apelin receptor 5VBL apelin receptor 5VBL
TM5 230 5.48x48 apelin receptor 5VBL S1P1 receptor 3V2Y
TM5 231 5.49x49 apelin receptor 5VBL NTS1 receptor 4BUO
TM5 232 5.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM5 233 5.51x51 apelin receptor 5VBL apelin receptor 5VBL
TM5 234 5.52x52 apelin receptor 5VBL CXCR4 3ODU
TM5 235 5.53x53 apelin receptor 5VBL C5a1 receptor 5O9H
TM5 236 5.54x54 apelin receptor 5VBL ETB receptor 5X93
TM5 237 5.55x55 apelin receptor 5VBL CCR5 5UIW
TM5 238 5.56x56 apelin receptor 5VBL apelin receptor 5VBL
TM5 239 5.57x57 apelin receptor 5VBL apelin receptor 5VBL
TM5 240 5.58x58 apelin receptor 5VBL apelin receptor 5VBL
TM5 241 5.59x59 apelin receptor 5VBL OX2 receptor 5WS3
TM5 242 5.60x60 apelin receptor 5VBL AT1 receptor 4ZUD
TM5 243 5.61x61 apelin receptor 5VBL apelin receptor 5VBL
TM5 244 5.62x62 apelin receptor 5VBL κ receptor 4DJH
TM5 245 5.63x63 apelin receptor 5VBL NOP receptor 5DHG
TM5 246 5.64x64 apelin receptor 5VBL - -
TM5 247 5.65x65 apelin receptor 5VBL AT1 receptor 4YAY
TM5 248 5.66x66 apelin receptor 5VBL δ receptor 4N6H
TM5 249 5.67x67 LPA6 receptor 5XSZ - -
ICL3 250 - - - -
ICL3 251 - - - -
ICL3 252 - - - -
ICL3 253 - - - -
TM6 254 6.26x26 AT2 receptor 5UNG - -
TM6 255 6.27x27 AT2 receptor 5UNG - -
TM6 256 6.28x28 AT2 receptor 5UNG NOP receptor 5DHG
TM6 257 6.29x29 AT2 receptor 5UNG - -
TM6 258 6.30x30 AT2 receptor 5UNG CCR9 5LWE
TM6 259 6.31x31 apelin receptor 5VBL C5a1 receptor 5O9H
TM6 260 6.32x32 apelin receptor 5VBL CCR9 5LWE
TM6 261 6.33x33 apelin receptor 5VBL CCR2 5T1A
TM6 262 6.34x34 apelin receptor 5VBL CCR5 5UIW
TM6 263 6.35x35 apelin receptor 5VBL κ receptor 4DJH
TM6 264 6.36x36 apelin receptor 5VBL δ receptor 4N6H
TM6 265 6.37x37 apelin receptor 5VBL apelin receptor 5VBL
TM6 266 6.38x38 apelin receptor 5VBL D2 receptor 6CM4
TM6 267 6.39x39 apelin receptor 5VBL CXCR4 3ODU
TM6 268 6.40x40 apelin receptor 5VBL κ receptor 4DJH
TM6 269 6.41x41 apelin receptor 5VBL CCR9 5LWE
TM6 270 6.42x42 apelin receptor 5VBL κ receptor 4DJH
TM6 271 6.43x43 apelin receptor 5VBL LPA6 receptor 5XSZ
TM6 272 6.44x44 apelin receptor 5VBL apelin receptor 5VBL
TM6 273 6.45x45 apelin receptor 5VBL Rhodopsin 1GZM
TM6 274 6.46x46 apelin receptor 5VBL κ receptor 4DJH
TM6 275 6.47x47 apelin receptor 5VBL apelin receptor 5VBL
TM6 276 6.48x48 apelin receptor 5VBL LPA6 receptor 5XSZ
TM6 277 6.49x49 apelin receptor 5VBL PAF receptor 5ZKP
TM6 278 6.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM6 279 6.51x51 apelin receptor 5VBL apelin receptor 5VBL
TM6 280 6.52x52 apelin receptor 5VBL apelin receptor 5VBL
TM6 281 6.53x53 apelin receptor 5VBL C5a1 receptor 5O9H
TM6 282 6.54x54 apelin receptor 5VBL LPA6 receptor 5XSZ
TM6 283 6.55x55 apelin receptor 5VBL ETB receptor 5X93
TM6 284 6.56x56 apelin receptor 5VBL CXCR4 3ODU
TM6 285 6.57x57 apelin receptor 5VBL CCR9 5LWE
TM6 286 6.58x58 apelin receptor 5VBL apelin receptor 5VBL
TM6 287 6.59x59 apelin receptor 5VBL AT1 receptor 4ZUD
TM6 288 6.60x60 apelin receptor 5VBL apelin receptor 5VBL
TM6 289 6.61x61 apelin receptor 5VBL Rhodopsin 1GZM
TM6 290 6.62x62 apelin receptor 5VBL - -
TM6 291 6.63x63 apelin receptor 5VBL - -
TM6 292 6.64x64 LPA6 receptor 5XSZ - -
ECL3 293 apelin receptor 5VBL - -
ECL3 294 apelin receptor 5VBL - -
ECL3 295 apelin receptor 5VBL - -
TM7 296 7.24x23 apelin receptor 5VBL AT2 receptor 5UNG
TM7 297 7.25x24 apelin receptor 5VBL apelin receptor 5VBL
TM7 298 7.26x25 apelin receptor 5VBL CCR9 5LWE
TM7 299 7.27x26 apelin receptor 5VBL C5a1 receptor 5O9H
TM7 300 7.28x27 apelin receptor 5VBL 5-HT2C receptor 6BQH
TM7 301 7.29x28 apelin receptor 5VBL US28 4XT1
TM7 302 7.30x29 apelin receptor 5VBL AT1 receptor 4ZUD
TM7 303 7.31x30 apelin receptor 5VBL apelin receptor 5VBL
TM7 304 7.32x31 apelin receptor 5VBL FFA1 receptor 5KW2
TM7 305 7.33x32 apelin receptor 5VBL Y1 receptor 5ZBH
TM7 306 7.34x33 apelin receptor 5VBL AT1 receptor 4ZUD
TM7 307 7.35x34 apelin receptor 5VBL - -
TM7 308 7.36x35 apelin receptor 5VBL NOP receptor 5DHG
TM7 309 7.37x36 apelin receptor 5VBL AT1 receptor 4ZUD
TM7 310 7.38x37 apelin receptor 5VBL AT1 receptor 4ZUD
TM7 311 7.39x38 apelin receptor 5VBL CB1 receptor 5TGZ
TM7 312 7.40x39 apelin receptor 5VBL apelin receptor 5VBL
TM7 313 7.41x40 apelin receptor 5VBL κ receptor 4DJH
TM7 314 7.42x41 apelin receptor 5VBL A1 receptor 5UEN
TM7 315 7.43x42 apelin receptor 5VBL ETB receptor 5X93
TM7 316 7.44x43 apelin receptor 5VBL BLT1 receptor 5X33
TM7 317 7.45x45 apelin receptor 5VBL apelin receptor 5VBL
TM7 318 7.46x46 apelin receptor 5VBL - -
TM7 319 7.47x47 apelin receptor 5VBL OX2 receptor 5WS3
TM7 320 7.48x48 apelin receptor 5VBL apelin receptor 5VBL
TM7 321 7.49x49 apelin receptor 5VBL LPA6 receptor 5XSZ
TM7 322 7.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM7 323 7.51x51 apelin receptor 5VBL κ receptor 4DJH
TM7 324 7.52x52 apelin receptor 5VBL - -
TM7 325 7.53x53 apelin receptor 5VBL apelin receptor 5VBL
TM7 326 7.54x54 apelin receptor 5VBL P2Y1 receptor 4XNW
TM7 327 7.55x55 apelin receptor 5VBL apelin receptor 5VBL
TM7 328 7.56x56 apelin receptor 5VBL CCR5 5UIW
H8 329 8.47x47 apelin receptor 5VBL - -
H8 330 8.48x48 apelin receptor 5VBL CCR5 4MBS
H8 331 8.49x49 apelin receptor 5VBL CCR2 5T1A
H8 332 8.50x50 apelin receptor 5VBL apelin receptor 5VBL
H8 333 8.51x51 apelin receptor 5VBL apelin receptor 5VBL
H8 334 8.52x52 apelin receptor 5VBL CB1 receptor 5TGZ
H8 335 8.53x53 apelin receptor 5VBL apelin receptor 5VBL
H8 336 8.54x54 apelin receptor 5VBL CCR5 5UIW
H8 337 8.55x55 apelin receptor 5VBL - -
H8 338 8.56x56 apelin receptor 5VBL 5-HT2C receptor 6BQH
H8 339 8.57x57 apelin receptor 5VBL δ receptor 4N6H
H8 340 8.58x58 apelin receptor 5VBL apelin receptor 5VBL
H8 341 8.59x59 apelin receptor 5VBL ETB receptor 5X93
H8 342 8.60x60 apelin receptor 5VBL - -
H8 343 8.61x61 apelin receptor 5VBL - -
C-term 344 apelin receptor 5VBL apelin receptor 5VBL
C-term 345 apelin receptor 5VBL apelin receptor 5VBL
C-term 346 apelin receptor 5VBL apelin receptor 5VBL
C-term 347 - - - -
C-term 348 - - - -