GPR83 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.69 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 46%) PDB: 6B73

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 73.8 16.3 10.0
Side-chains 19.6 54.8 25.6

Number of backbone templates: 5
Number of rotamer templates: 40

NGL is a WebGL based 3D viewer powered by MMTF.

6B73
5WS3
5WQC
3SN6
4UHR
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 65 - - - -
N-term 66 - - - -
N-term 67 κ receptor 6B73 κ receptor 6B73
N-term 68 κ receptor 6B73 κ receptor 6B73
N-term 69 κ receptor 6B73 κ receptor 6B73
TM1 70 1.31x31 κ receptor 6B73 LPA1 receptor 4Z35
TM1 71 1.32x32 κ receptor 6B73 US28 4XT1
TM1 72 1.33x33 κ receptor 6B73 A1 receptor 6D9H
TM1 73 1.34x34 κ receptor 6B73 5-HT1B receptor 6G79
TM1 74 1.35x35 κ receptor 6B73 Rhodopsin 4ZWJ
TM1 75 1.36x36 κ receptor 6B73 A2A receptor 5G53
TM1 76 1.37x37 κ receptor 6B73 CB1 receptor 5XRA
TM1 77 1.38x38 κ receptor 6B73 OX1 receptor 4ZJ8
TM1 78 1.39x39 κ receptor 6B73 κ receptor 6B73
TM1 79 1.40x40 κ receptor 6B73 κ receptor 6B73
TM1 80 1.41x41 κ receptor 6B73 M3 receptor 4U15
TM1 81 1.42x42 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 82 1.43x43 κ receptor 6B73 Rhodopsin 4ZWJ
TM1 83 1.44x44 κ receptor 6B73 κ receptor 6B73
TM1 84 1.45x45 κ receptor 6B73 US28 4XT1
TM1 85 1.46x46 κ receptor 6B73 A1 receptor 6D9H
TM1 86 1.47x47 κ receptor 6B73 κ receptor 6B73
TM1 87 1.48x48 κ receptor 6B73 μ receptor 5C1M
TM1 88 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 89 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 90 1.51x51 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 91 1.52x52 κ receptor 6B73 κ receptor 6B73
TM1 92 1.53x53 κ receptor 6B73 κ receptor 6B73
TM1 93 1.54x54 κ receptor 6B73 A2A receptor 5G53
TM1 94 1.55x55 κ receptor 6B73 - -
TM1 95 1.56x56 κ receptor 6B73 κ receptor 6B73
TM1 96 1.57x57 κ receptor 6B73 κ receptor 6B73
TM1 97 1.58x58 κ receptor 6B73 apelin receptor 5VBL
TM1 98 1.59x59 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 99 1.60x60 κ receptor 6B73 - -
ICL1 100 12.48x48 - - - -
ICL1 101 12.49x49 OX2 receptor 5WS3 β2-adrenoceptor 4LDE
ICL1 102 12.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL1 103 12.51x51 - - - -
TM2 104 2.37x37 κ receptor 6B73 CCR5 5UIW
TM2 105 2.38x38 κ receptor 6B73 κ receptor 6B73
TM2 106 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 107 2.40x40 κ receptor 6B73 AT2 receptor 5UNG
TM2 108 2.41x41 κ receptor 6B73 H1 receptor 3RZE
TM2 109 2.42x42 κ receptor 6B73 β2-adrenoceptor 3SN6
TM2 110 2.43x43 κ receptor 6B73 κ receptor 6B73
TM2 111 2.44x44 κ receptor 6B73 A2A receptor 5G53
TM2 112 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 113 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 114 2.47x47 κ receptor 6B73 κ receptor 6B73
TM2 115 2.48x48 κ receptor 6B73 Rhodopsin 4ZWJ
TM2 116 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 117 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 118 2.51x51 κ receptor 6B73 A2A receptor 5G53
TM2 119 2.52x52 κ receptor 6B73 - -
TM2 120 2.53x53 κ receptor 6B73 NTS1 receptor 5T04
TM2 121 2.54x54 κ receptor 6B73 κ receptor 6B73
TM2 122 2.55x55 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM2 123 2.56x551 OX2 receptor 5WS3 5-HT1B receptor 6G79
TM2 124 2.57x56 OX2 receptor 5WS3 - -
TM2 125 2.58x57 κ receptor 6B73 - -
TM2 126 2.59x58 κ receptor 6B73 κ receptor 6B73
TM2 127 2.60x59 κ receptor 6B73 κ receptor 6B73
TM2 128 2.61x60 κ receptor 6B73 Rhodopsin 4ZWJ
TM2 129 2.62x61 κ receptor 6B73 Rhodopsin 4ZWJ
TM2 130 2.63x62 κ receptor 6B73 μ receptor 5C1M
TM2 131 2.64x63 κ receptor 6B73 - -
TM2 132 2.65x64 κ receptor 6B73 LPA6 receptor 5XSZ
TM2 133 2.66x65 κ receptor 6B73 5-HT1B receptor 6G79
TM2 134 2.67x66 κ receptor 6B73 PAF receptor 5ZKP
TM2 135 2.68x67 OX2 receptor 5WS3 FFA1 receptor 5TZR
ECL1 136 23.49x49 - - - -
ECL1 137 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 138 23.51x51 OX2 receptor 5WS3 PAF receptor 5ZKP
ECL1 139 23.52x52 - - - -
TM3 140 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 141 3.22x22 κ receptor 6B73 PAF receptor 5ZKP
TM3 142 3.23x23 κ receptor 6B73 - -
TM3 143 3.24x24 κ receptor 6B73 AT2 receptor 5UNG
TM3 144 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 145 3.26x26 κ receptor 6B73 - -
TM3 146 3.27x27 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 147 3.28x28 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 148 3.29x29 κ receptor 6B73 P2Y1 receptor 4XNW
TM3 149 3.30x30 κ receptor 6B73 Rhodopsin 4ZWJ
TM3 150 3.31x31 κ receptor 6B73 PAR1 3VW7
TM3 151 3.32x32 κ receptor 6B73 OX2 receptor 5WS3
TM3 152 3.33x33 κ receptor 6B73 κ receptor 6B73
TM3 153 3.34x34 κ receptor 6B73 PAR1 3VW7
TM3 154 3.35x35 κ receptor 6B73 CB1 receptor 5XRA
TM3 155 3.36x36 κ receptor 6B73 AT1 receptor 4ZUD
TM3 156 3.37x37 κ receptor 6B73 - -
TM3 157 3.38x38 κ receptor 6B73 OX2 receptor 5WS3
TM3 158 3.39x39 κ receptor 6B73 κ receptor 6B73
TM3 159 3.40x40 κ receptor 6B73 NTS1 receptor 5T04
TM3 160 3.41x41 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 161 3.42x42 κ receptor 6B73 κ receptor 6B73
TM3 162 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 163 3.44x44 κ receptor 6B73 κ receptor 6B73
TM3 164 3.45x45 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 165 3.46x46 κ receptor 6B73 β2-adrenoceptor 3SN6
TM3 166 3.47x47 κ receptor 6B73 β2-adrenoceptor 3SN6
TM3 167 3.48x48 κ receptor 6B73 κ receptor 6B73
TM3 168 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 169 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 170 3.51x51 κ receptor 6B73 Y1 receptor 5ZBH
TM3 171 3.52x52 κ receptor 6B73 AT2 receptor 5UNG
TM3 172 3.53x53 κ receptor 6B73 Rhodopsin 4ZWJ
TM3 173 3.54x54 κ receptor 6B73 β2-adrenoceptor 3SN6
TM3 174 3.55x55 κ receptor 6B73 - -
TM3 175 3.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 176 - - - -
ICL2 177 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL2 178 OX2 receptor 5WS3 - -
ICL2 179 OX2 receptor 5WS3 - -
ICL2 180 OX2 receptor 5WS3 - -
ICL2 181 - - - -
TM4 182 4.38x38 κ receptor 6B73 NTS1 receptor 5T04
TM4 183 4.39x39 κ receptor 6B73 - -
TM4 184 4.40x40 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 185 4.41x41 κ receptor 6B73 κ receptor 6B73
TM4 186 4.42x42 κ receptor 6B73 CCR2 5T1A
TM4 187 4.43x43 κ receptor 6B73 CB1 receptor 5XRA
TM4 188 4.44x44 κ receptor 6B73 κ receptor 6B73
TM4 189 4.45x45 κ receptor 6B73 - -
TM4 190 4.46x46 κ receptor 6B73 β2-adrenoceptor 3SN6
TM4 191 4.47x47 κ receptor 6B73 Rhodopsin 4ZWJ
TM4 192 4.48x48 κ receptor 6B73 5-HT2B receptor 5TUD
TM4 193 4.49x49 κ receptor 6B73 κ receptor 6B73
TM4 194 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 195 4.51x51 κ receptor 6B73 CB1 receptor 5XRA
TM4 196 4.52x52 κ receptor 6B73 Rhodopsin 4ZWJ
TM4 197 4.53x53 κ receptor 6B73 Rhodopsin 4ZWJ
TM4 198 4.54x54 κ receptor 6B73 - -
TM4 199 4.55x55 κ receptor 6B73 CCR2 5T1A
TM4 200 4.56x56 κ receptor 6B73 - -
TM4 201 4.57x57 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM4 202 4.58x59 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM4 203 4.59x60 κ receptor 6B73 β2-adrenoceptor 3SN6
TM4 204 4.60x61 κ receptor 6B73 US28 4XT1
TM4 205 4.61x62 κ receptor 6B73 Rhodopsin 4ZWJ
TM4 206 4.62x63 κ receptor 6B73 5-HT2B receptor 5TUD
TM4 207 4.63x64 κ receptor 6B73 - -
TM4 208 4.64x65 OX2 receptor 5WS3 Y1 receptor 5ZBQ
ECL2 209 - - - -
ECL2 210 OX2 receptor 5WQC - -
ECL2 211 OX2 receptor 5WQC - -
ECL2 212 OX2 receptor 5WQC OX2 receptor 5WQC
ECL2 213 OX2 receptor 5WQC - -
ECL2 214 OX2 receptor 5WQC - -
ECL2 215 OX2 receptor 5WQC - -
ECL2 216 - - - -
ECL2 217 - - - -
ECL2 218 - - - -
ECL2 219 OX2 receptor 5WQC - -
ECL2 220 OX2 receptor 5WQC - -
ECL2 221 OX2 receptor 5WQC - -
ECL2 222 OX2 receptor 5WQC - -
ECL2 223 - - - -
ECL2 224 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 225 45.51x51 κ receptor 6B73 A2A receptor 5G53
ECL2 226 45.52x52 κ receptor 6B73 NTS1 receptor 5T04
ECL2 227 - - - -
ECL2 228 - - - -
ECL2 229 - - - -
ECL2 230 - - - -
ECL2 231 - - - -
ECL2 232 - - - -
ECL2 233 - - - -
TM5 234 5.33x34 κ receptor 6B73 OX1 receptor 4ZJ8
TM5 235 5.34x35 κ receptor 6B73 - -
TM5 236 5.35x36 κ receptor 6B73 - -
TM5 237 5.36x37 κ receptor 6B73 NTS1 receptor 5T04
TM5 238 5.37x38 κ receptor 6B73 PAR1 3VW7
TM5 239 5.38x39 κ receptor 6B73 μ receptor 5C1M
TM5 240 5.39x40 κ receptor 6B73 ETB receptor 5X93
TM5 241 5.40x41 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 242 5.41x42 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 243 5.42x43 κ receptor 6B73 M2 receptor 4MQT
TM5 244 5.43x44 κ receptor 6B73 κ receptor 6B73
TM5 245 5.44x45 κ receptor 6B73 κ receptor 6B73
TM5 246 5.45x46 κ receptor 6B73 AT2 receptor 5UNG
TM5 247 5.46x461 κ receptor 6B73 FFA1 receptor 5TZY
TM5 248 5.47x47 κ receptor 6B73 OX2 receptor 5WS3
TM5 249 5.48x48 κ receptor 6B73 μ receptor 5C1M
TM5 250 5.49x49 κ receptor 6B73 M2 receptor 4MQT
TM5 251 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 252 5.51x51 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 253 5.52x52 κ receptor 6B73 κ receptor 6B73
TM5 254 5.53x53 κ receptor 6B73 κ receptor 6B73
TM5 255 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 256 5.55x55 κ receptor 6B73 US28 4XT1
TM5 257 5.56x56 κ receptor 6B73 κ receptor 6B73
TM5 258 5.57x57 κ receptor 6B73 CB1 receptor 5XRA
TM5 259 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 260 5.59x59 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 261 5.60x60 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 262 5.61x61 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 263 5.62x62 κ receptor 6B73 NTS1 receptor 5T04
TM5 264 5.63x63 κ receptor 6B73 AT2 receptor 5UNG
TM5 265 5.64x64 κ receptor 6B73 NTS1 receptor 5T04
TM5 266 5.65x65 κ receptor 6B73 κ receptor 6B73
TM5 267 5.66x66 κ receptor 6B73 OX2 receptor 5WS3
TM5 268 5.67x67 κ receptor 6B73 - -
TM5 269 5.68x68 β2-adrenoceptor 3SN6 - -
TM5 270 5.69x69 β2-adrenoceptor 3SN6 - -
TM5 271 5.70x70 β2-adrenoceptor 3SN6 - -
TM5 272 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 273 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 274 5.73x73 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
ICL3 275 - - - -
ICL3 276 - - - -
ICL3 277 - - - -
ICL3 278 - - - -
TM6 279 6.22x22 A2A receptor 4UHR - -
TM6 280 6.23x23 κ receptor 6B73 - -
TM6 281 6.24x24 κ receptor 6B73 - -
TM6 282 6.25x25 κ receptor 6B73 - -
TM6 283 6.26x26 κ receptor 6B73 FFA1 receptor 5TZR
TM6 284 6.27x27 κ receptor 6B73 AT2 receptor 5UNG
TM6 285 6.28x28 κ receptor 6B73 μ receptor 6DDF
TM6 286 6.29x29 κ receptor 6B73 β2-adrenoceptor 4LDE
TM6 287 6.30x30 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 288 6.31x31 κ receptor 6B73 Rhodopsin 4ZWJ
TM6 289 6.32x32 κ receptor 6B73 β2-adrenoceptor 3P0G
TM6 290 6.33x33 κ receptor 6B73 OX2 receptor 5WS3
TM6 291 6.34x34 κ receptor 6B73 - -
TM6 292 6.35x35 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 293 6.36x36 κ receptor 6B73 μ receptor 5C1M
TM6 294 6.37x37 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 295 6.38x38 κ receptor 6B73 OX2 receptor 5WS3
TM6 296 6.39x39 κ receptor 6B73 CB1 receptor 5XRA
TM6 297 6.40x40 κ receptor 6B73 κ receptor 6B73
TM6 298 6.41x41 κ receptor 6B73 κ receptor 6B73
TM6 299 6.42x42 κ receptor 6B73 CB1 receptor 5XRA
TM6 300 6.43x43 κ receptor 6B73 A2A receptor 5G53
TM6 301 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 302 6.45x45 κ receptor 6B73 A2A receptor 5G53
TM6 303 6.46x46 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 304 6.47x47 κ receptor 6B73 κ receptor 6B73
TM6 305 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 306 6.49x49 κ receptor 6B73 CCR9 5LWE
TM6 307 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 308 6.51x51 κ receptor 6B73 A2A receptor 5G53
TM6 309 6.52x52 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 310 6.53x53 κ receptor 6B73 CCR9 5LWE
TM6 311 6.54x54 κ receptor 6B73 μ receptor 5C1M
TM6 312 6.55x55 κ receptor 6B73 μ receptor 5C1M
TM6 313 6.56x56 κ receptor 6B73 κ receptor 6B73
TM6 314 6.57x57 κ receptor 6B73 5-HT2C receptor 6BQG
TM6 315 6.58x58 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 316 6.59x59 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 317 6.60x60 κ receptor 6B73 PAR1 3VW7
TM6 318 6.61x61 κ receptor 6B73 - -
ECL3 319 - - - -
ECL3 320 κ receptor 6B73 - -
ECL3 321 κ receptor 6B73 - -
ECL3 322 κ receptor 6B73 - -
TM7 323 7.31x30 κ receptor 6B73 - -
TM7 324 7.32x31 κ receptor 6B73 M2 receptor 4MQT
TM7 325 7.33x32 κ receptor 6B73 5-HT1B receptor 6G79
TM7 326 7.34x33 κ receptor 6B73 5-HT2C receptor 6BQG
TM7 327 7.35x34 κ receptor 6B73 κ receptor 6B73
TM7 328 7.36x35 κ receptor 6B73 - -
TM7 329 7.37x36 κ receptor 6B73 D2 receptor 6CM4
TM7 330 7.38x37 κ receptor 6B73 5-HT1B receptor 6G79
TM7 331 7.39x38 κ receptor 6B73 OX2 receptor 5WS3
TM7 332 7.40x39 κ receptor 6B73 β2-adrenoceptor 3SN6
TM7 333 7.41x40 κ receptor 6B73 Rhodopsin 4ZWJ
TM7 334 7.42x41 κ receptor 6B73 Rhodopsin 4ZWJ
TM7 335 7.43x42 κ receptor 6B73 Y1 receptor 5ZBH
TM7 336 7.44x43 κ receptor 6B73 Rhodopsin 4ZWJ
TM7 337 7.45x45 κ receptor 6B73 Rhodopsin 5DYS
TM7 338 7.46x46 κ receptor 6B73 Y1 receptor 5ZBH
TM7 339 7.47x47 κ receptor 6B73 μ receptor 5C1M
TM7 340 7.48x48 κ receptor 6B73 Rhodopsin 4ZWJ
TM7 341 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 342 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 343 7.51x51 κ receptor 6B73 AT2 receptor 5UNG
TM7 344 7.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 345 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 346 7.54x54 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM7 347 7.55x55 OX2 receptor 5WS3 - -
TM7 348 7.56x56 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 349 8.47x47 OX2 receptor 5WS3 Rhodopsin 4ZWJ
H8 350 8.48x48 OX2 receptor 5WS3 μ receptor 4DKL
H8 351 8.49x49 OX2 receptor 5WS3 Y1 receptor 5ZBH
H8 352 8.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 353 8.51x51 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 354 8.52x52 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
H8 355 8.53x53 OX2 receptor 5WS3 US28 4XT1
H8 356 8.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 357 8.55x55 OX2 receptor 5WS3 M2 receptor 4MQT
H8 358 8.56x56 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 359 8.57x57 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
H8 360 8.58x58 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
C-term 361 - - - -
C-term 362 - - - -
C-term 363 - - - -
C-term 364 - - - -
C-term 365 - - - -