MCH1 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 7.22 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 51%) PDB: 4DJH

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 86.0 8.3 5.7
Side-chains 25.3 54.0 20.7

Number of backbone templates: 7
Number of rotamer templates: 40

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4DJH
6B73
4XES
5X33
4ZUD
4N6H
3VG9
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 102 - - - -
N-term 103 - - - -
N-term 104 - - - -
N-term 105 κ receptor 4DJH κ receptor 4DJH
N-term 106 κ receptor 4DJH κ receptor 4DJH
TM1 107 1.30x30 κ receptor 4DJH AT1 receptor 4ZUD
TM1 108 1.31x31 κ receptor 4DJH κ receptor 4DJH
TM1 109 1.32x32 κ receptor 4DJH - -
TM1 110 1.33x33 κ receptor 4DJH δ receptor 4N6H
TM1 111 1.34x34 κ receptor 4DJH κ receptor 4DJH
TM1 112 1.35x35 κ receptor 4DJH β2-adrenoceptor 5JQH
TM1 113 1.36x36 κ receptor 4DJH AT1 receptor 4ZUD
TM1 114 1.37x37 κ receptor 4DJH PAR1 3VW7
TM1 115 1.38x38 κ receptor 4DJH κ receptor 4DJH
TM1 116 1.39x39 κ receptor 4DJH C5a1 receptor 5O9H
TM1 117 1.40x40 κ receptor 4DJH M4 receptor 5DSG
TM1 118 1.41x41 κ receptor 4DJH H1 receptor 3RZE
TM1 119 1.42x42 κ receptor 4DJH AT1 receptor 4ZUD
TM1 120 1.43x43 κ receptor 4DJH NOP receptor 5DHG
TM1 121 1.44x44 κ receptor 4DJH CXCR4 3ODU
TM1 122 1.45x45 κ receptor 4DJH apelin receptor 5VBL
TM1 123 1.46x46 κ receptor 4DJH κ receptor 4DJH
TM1 124 1.47x47 κ receptor 4DJH AT1 receptor 4ZUD
TM1 125 1.48x48 κ receptor 4DJH OX2 receptor 5WS3
TM1 126 1.49x49 κ receptor 4DJH κ receptor 4DJH
TM1 127 1.50x50 κ receptor 4DJH κ receptor 4DJH
TM1 128 1.51x51 κ receptor 4DJH κ receptor 4DJH
TM1 129 1.52x52 κ receptor 4DJH ETB receptor 5X93
TM1 130 1.53x53 κ receptor 4DJH κ receptor 4DJH
TM1 131 1.54x54 κ receptor 4DJH CXCR4 3ODU
TM1 132 1.55x55 κ receptor 4DJH κ receptor 4DJH
TM1 133 1.56x56 κ receptor 4DJH H1 receptor 3RZE
TM1 134 1.57x57 κ receptor 4DJH apelin receptor 5VBL
TM1 135 1.58x58 κ receptor 4DJH δ receptor 4N6H
TM1 136 1.59x59 κ receptor 4DJH OX2 receptor 5WS3
TM1 137 1.60x60 κ receptor 4DJH - -
ICL1 138 12.48x48 κ receptor 4DJH A2A receptor 3VG9
ICL1 139 12.49x49 κ receptor 4DJH δ receptor 4N6H
ICL1 140 12.50x50 κ receptor 4DJH δ receptor 4EJ4
ICL1 141 12.51x51 κ receptor 4DJH H1 receptor 3RZE
TM2 142 2.34x34 NTS1 receptor 4XES - -
TM2 143 2.35x35 NTS1 receptor 4XES - -
TM2 144 2.36x36 NTS1 receptor 4XES - -
TM2 145 2.37x37 κ receptor 4DJH 5-HT2C receptor 6BQH
TM2 146 2.38x38 κ receptor 4DJH AT1 receptor 4ZUD
TM2 147 2.39x39 κ receptor 4DJH ETB receptor 5X93
TM2 148 2.40x40 κ receptor 4DJH CXCR4 3ODU
TM2 149 2.41x41 κ receptor 4DJH κ receptor 4DJH
TM2 150 2.42x42 κ receptor 4DJH AT1 receptor 4ZUD
TM2 151 2.43x43 κ receptor 4DJH κ receptor 4DJH
TM2 152 2.44x44 κ receptor 4DJH US28 4XT1
TM2 153 2.45x45 κ receptor 4DJH κ receptor 4DJH
TM2 154 2.46x46 κ receptor 4DJH κ receptor 4DJH
TM2 155 2.47x47 κ receptor 4DJH CXCR4 3ODU
TM2 156 2.48x48 κ receptor 4DJH CXCR4 3ODU
TM2 157 2.49x49 κ receptor 4DJH - -
TM2 158 2.50x50 κ receptor 4DJH κ receptor 4DJH
TM2 159 2.51x51 κ receptor 4DJH AT1 receptor 4ZUD
TM2 160 2.52x52 κ receptor 4DJH κ receptor 4DJH
TM2 161 2.53x53 κ receptor 4DJH AT1 receptor 4ZUD
TM2 162 2.54x54 κ receptor 4DJH NOP receptor 5DHG
TM2 163 2.55x55 κ receptor 4DJH NOP receptor 5DHG
TM2 164 2.56x56 κ receptor 4DJH Rhodopsin 1GZM
TM2 165 2.57x57 κ receptor 4DJH κ receptor 4DJH
TM2 166 2.58x58 κ receptor 4DJH κ receptor 4DJH
TM2 167 2.59x59 κ receptor 4DJH κ receptor 4DJH
TM2 168 2.60x60 κ receptor 4DJH - -
TM2 169 2.61x61 κ receptor 4DJH H1 receptor 3RZE
TM2 170 2.62x62 κ receptor 4DJH BLT1 receptor 5X33
TM2 171 2.63x63 κ receptor 4DJH - -
TM2 172 2.64x64 κ receptor 4DJH BLT1 receptor 5X33
TM2 173 2.65x65 κ receptor 4DJH 5-HT2B receptor 4IB4
TM2 174 2.66x66 κ receptor 4DJH A2A receptor 3VG9
TM2 175 2.67x67 BLT1 receptor 5X33 κ receptor 4DJH
ECL1 176 - - - -
ECL1 177 23.49x49 κ receptor 4DJH 5-HT2C receptor 6BQH
ECL1 178 23.50x50 κ receptor 4DJH κ receptor 4DJH
ECL1 179 23.51x51 κ receptor 4DJH - -
ECL1 180 23.52x52 κ receptor 4DJH κ receptor 4DJH
TM3 181 3.21x21 κ receptor 4DJH κ receptor 4DJH
TM3 182 3.22x22 κ receptor 4DJH δ receptor 4N6H
TM3 183 3.23x23 κ receptor 4DJH CCR5 5UIW
TM3 184 3.24x24 κ receptor 4DJH CCR5 5UIW
TM3 185 3.25x25 κ receptor 4DJH κ receptor 4DJH
TM3 186 3.26x26 κ receptor 4DJH US28 4XT1
TM3 187 3.27x27 κ receptor 4DJH BLT1 receptor 5X33
TM3 188 3.28x28 κ receptor 4DJH OX2 receptor 5WS3
TM3 189 3.29x29 κ receptor 4DJH CCR5 5UIW
TM3 190 3.30x30 κ receptor 4DJH NOP receptor 5DHG
TM3 191 3.31x31 κ receptor 4DJH H1 receptor 3RZE
TM3 192 3.32x32 κ receptor 4DJH κ receptor 4DJH
TM3 193 3.33x33 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 194 3.34x34 κ receptor 4DJH - -
TM3 195 3.35x35 κ receptor 4DJH BLT1 receptor 5X33
TM3 196 3.36x36 κ receptor 4DJH - -
TM3 197 3.37x37 κ receptor 4DJH κ receptor 4DJH
TM3 198 3.38x38 κ receptor 4DJH κ receptor 4DJH
TM3 199 3.39x39 κ receptor 4DJH κ receptor 4DJH
TM3 200 3.40x40 κ receptor 4DJH NOP receptor 5DHG
TM3 201 3.41x41 κ receptor 4DJH - -
TM3 202 3.42x42 κ receptor 4DJH CXCR4 3ODU
TM3 203 3.43x43 κ receptor 4DJH κ receptor 4DJH
TM3 204 3.44x44 κ receptor 4DJH κ receptor 4DJH
TM3 205 3.45x45 κ receptor 4DJH NOP receptor 5DHG
TM3 206 3.46x46 κ receptor 4DJH κ receptor 4DJH
TM3 207 3.47x47 κ receptor 4DJH OX2 receptor 5WS3
TM3 208 3.48x48 κ receptor 4DJH AT1 receptor 4ZUD
TM3 209 3.49x49 κ receptor 4DJH κ receptor 4DJH
TM3 210 3.50x50 κ receptor 4DJH κ receptor 4DJH
TM3 211 3.51x51 κ receptor 4DJH κ receptor 4DJH
TM3 212 3.52x52 κ receptor 4DJH AT1 receptor 4ZUD
TM3 213 3.53x53 κ receptor 4DJH κ receptor 4DJH
TM3 214 3.54x54 κ receptor 4DJH P2Y12 receptor 4NTJ
TM3 215 3.55x55 κ receptor 4DJH AT1 receptor 4ZUD
TM3 216 3.56x56 κ receptor 4DJH κ receptor 4DJH
ICL2 217 34.50x50 - - - -
ICL2 218 34.51x51 κ receptor 6B73 C5a1 receptor 6C1R
ICL2 219 34.52x52 κ receptor 6B73 M1 receptor 5CXV
ICL2 220 34.53x53 κ receptor 6B73 BLT1 receptor 5X33
ICL2 221 34.54x54 κ receptor 6B73 - -
ICL2 222 34.55x55 κ receptor 6B73 BLT1 receptor 5X33
ICL2 223 34.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 224 34.57x57 - - - -
TM4 225 4.38x38 κ receptor 4DJH CXCR4 3ODU
TM4 226 4.39x39 κ receptor 4DJH κ receptor 4DJH
TM4 227 4.40x40 κ receptor 4DJH NOP receptor 5DHG
TM4 228 4.41x41 κ receptor 4DJH AT1 receptor 4ZUD
TM4 229 4.42x42 κ receptor 4DJH κ receptor 4DJH
TM4 230 4.43x43 κ receptor 4DJH D2 receptor 6CM4
TM4 231 4.44x44 κ receptor 4DJH δ receptor 4N6H
TM4 232 4.45x45 κ receptor 4DJH NOP receptor 5DHG
TM4 233 4.46x46 κ receptor 4DJH H1 receptor 3RZE
TM4 234 4.47x47 κ receptor 4DJH CB1 receptor 5TGZ
TM4 235 4.48x48 κ receptor 4DJH ETB receptor 5X93
TM4 236 4.49x49 κ receptor 4DJH apelin receptor 5VBL
TM4 237 4.50x50 κ receptor 4DJH κ receptor 4DJH
TM4 238 4.51x51 κ receptor 4DJH NOP receptor 5DHG
TM4 239 4.52x52 κ receptor 4DJH κ receptor 4DJH
TM4 240 4.53x53 κ receptor 4DJH κ receptor 4DJH
TM4 241 4.54x54 κ receptor 4DJH BLT1 receptor 5X33
TM4 242 4.55x55 κ receptor 4DJH OX2 receptor 5WS3
TM4 243 4.56x56 κ receptor 4DJH Y1 receptor 5ZBH
TM4 244 4.57x57 AT1 receptor 4ZUD P2Y1 receptor 4XNW
TM4 245 4.58x59 AT1 receptor 4ZUD BLT1 receptor 5X33
TM4 246 4.59x60 κ receptor 4DJH AT1 receptor 4ZUD
TM4 247 4.60x61 κ receptor 4DJH BLT1 receptor 5X33
TM4 248 4.61x62 κ receptor 4DJH - -
TM4 249 4.62x63 κ receptor 4DJH κ receptor 4DJH
TM4 250 4.63x64 κ receptor 4DJH - -
TM4 251 4.64x65 AT1 receptor 4ZUD CXCR4 3ODU
ECL2 252 κ receptor 4DJH - -
ECL2 253 κ receptor 4DJH - -
ECL2 254 κ receptor 4DJH - -
ECL2 255 κ receptor 4DJH - -
ECL2 256 κ receptor 4DJH - -
ECL2 257 κ receptor 4DJH - -
ECL2 258 κ receptor 4DJH - -
ECL2 259 κ receptor 4DJH - -
ECL2 260 κ receptor 4DJH - -
ECL2 261 κ receptor 4DJH κ receptor 4DJH
ECL2 262 κ receptor 4DJH - -
ECL2 263 45.50x50 κ receptor 4DJH κ receptor 4DJH
ECL2 264 45.51x51 κ receptor 4DJH C5a1 receptor 5O9H
ECL2 265 45.52x52 κ receptor 4DJH M4 receptor 5DSG
ECL2 266 - - - -
ECL2 267 - - - -
ECL2 268 - - - -
TM5 269 5.30x31 κ receptor 4DJH - -
TM5 270 5.31x32 κ receptor 4DJH - -
TM5 271 5.32x33 κ receptor 4DJH NOP receptor 5DHG
TM5 272 5.33x34 κ receptor 4DJH - -
TM5 273 5.34x35 κ receptor 4DJH PAR2 5NDD
TM5 274 5.35x36 κ receptor 4DJH NTS1 receptor 4BUO
TM5 275 5.36x37 κ receptor 4DJH PAR1 3VW7
TM5 276 5.37x38 κ receptor 4DJH H1 receptor 3RZE
TM5 277 5.38x39 κ receptor 4DJH NOP receptor 5DHG
TM5 278 5.39x40 κ receptor 4DJH CCR5 5UIW
TM5 279 5.40x41 κ receptor 4DJH AT1 receptor 4ZUD
TM5 280 5.41x42 κ receptor 4DJH D2 receptor 6CM4
TM5 281 5.42x43 κ receptor 4DJH - -
TM5 282 5.43x44 κ receptor 4DJH κ receptor 4DJH
TM5 283 5.44x45 κ receptor 4DJH BLT1 receptor 5X33
TM5 284 5.45x46 κ receptor 4DJH AT1 receptor 4YAY
TM5 285 5.46x461 κ receptor 4DJH κ receptor 4DJH
TM5 286 5.47x47 κ receptor 4DJH κ receptor 4DJH
TM5 287 5.48x48 κ receptor 4DJH - -
TM5 288 5.49x49 κ receptor 4DJH CXCR4 3ODU
TM5 289 5.50x50 κ receptor 4DJH κ receptor 4DJH
TM5 290 5.51x51 κ receptor 4DJH AT1 receptor 4ZUD
TM5 291 5.52x52 κ receptor 4DJH M4 receptor 5DSG
TM5 292 5.53x53 κ receptor 4DJH NOP receptor 5DHG
TM5 293 5.54x54 κ receptor 4DJH κ receptor 4DJH
TM5 294 5.55x55 κ receptor 4DJH δ receptor 4N6H
TM5 295 5.56x56 κ receptor 4DJH BLT1 receptor 5X33
TM5 296 5.57x57 κ receptor 4DJH OX2 receptor 5WS3
TM5 297 5.58x58 κ receptor 4DJH κ receptor 4DJH
TM5 298 5.59x59 κ receptor 4DJH PAR1 3VW7
TM5 299 5.60x60 κ receptor 4DJH D3 receptor 3PBL
TM5 300 5.61x61 κ receptor 4DJH AT1 receptor 4ZUD
TM5 301 5.62x62 κ receptor 4DJH δ receptor 4N6H
TM5 302 5.63x63 κ receptor 4DJH apelin receptor 5VBL
TM5 303 5.64x64 κ receptor 4DJH κ receptor 4DJH
TM5 304 5.65x65 κ receptor 4DJH ETB receptor 5X93
TM5 305 5.66x66 κ receptor 4DJH NTS1 receptor 4BUO
TM5 306 5.67x67 κ receptor 4DJH κ receptor 4DJH
TM5 307 5.68x68 κ receptor 4DJH P2Y12 receptor 4NTJ
ICL3 308 - - - -
ICL3 309 δ receptor 4N6H - -
ICL3 310 δ receptor 4N6H - -
ICL3 311 δ receptor 4N6H - -
ICL3 312 - - - -
TM6 313 6.23x23 κ receptor 6B73 - -
TM6 314 6.24x24 κ receptor 6B73 NOP receptor 5DHG
TM6 315 6.25x25 κ receptor 6B73 A2A receptor 3VG9
TM6 316 6.26x26 κ receptor 6B73 - -
TM6 317 6.27x27 κ receptor 6B73 LPA1 receptor 4Z35
TM6 318 6.28x28 κ receptor 4DJH β2-adrenoceptor 3SN6
TM6 319 6.29x29 κ receptor 4DJH H1 receptor 3RZE
TM6 320 6.30x30 κ receptor 4DJH Y1 receptor 5ZBH
TM6 321 6.31x31 κ receptor 4DJH Rhodopsin 1GZM
TM6 322 6.32x32 κ receptor 4DJH NOP receptor 5DHG
TM6 323 6.33x33 κ receptor 4DJH M4 receptor 5DSG
TM6 324 6.34x34 κ receptor 4DJH κ receptor 4DJH
TM6 325 6.35x35 κ receptor 4DJH κ receptor 4DJH
TM6 326 6.36x36 κ receptor 4DJH CXCR4 3ODU
TM6 327 6.37x37 κ receptor 4DJH D2 receptor 6CM4
TM6 328 6.38x38 κ receptor 4DJH CCR9 5LWE
TM6 329 6.39x39 κ receptor 4DJH AT1 receptor 4ZUD
TM6 330 6.40x40 κ receptor 4DJH AT1 receptor 4ZUD
TM6 331 6.41x41 κ receptor 4DJH - -
TM6 332 6.42x42 κ receptor 4DJH AT1 receptor 4ZUD
TM6 333 6.43x43 κ receptor 4DJH κ receptor 4DJH
TM6 334 6.44x44 κ receptor 4DJH κ receptor 4DJH
TM6 335 6.45x45 κ receptor 4DJH AT1 receptor 4ZUD
TM6 336 6.46x46 κ receptor 4DJH κ receptor 4DJH
TM6 337 6.47x47 κ receptor 4DJH κ receptor 4DJH
TM6 338 6.48x48 κ receptor 4DJH κ receptor 4DJH
TM6 339 6.49x49 κ receptor 4DJH δ receptor 4N6H
TM6 340 6.50x50 κ receptor 4DJH κ receptor 4DJH
TM6 341 6.51x51 κ receptor 4DJH CXCR4 3ODU
TM6 342 6.52x52 κ receptor 4DJH CXCR4 3ODU
TM6 343 6.53x53 κ receptor 4DJH NOP receptor 5DHG
TM6 344 6.54x54 κ receptor 4DJH OX2 receptor 5WS3
TM6 345 6.55x55 κ receptor 4DJH PAF receptor 5ZKP
TM6 346 6.56x56 κ receptor 4DJH κ receptor 4DJH
TM6 347 6.57x57 κ receptor 4DJH D4 receptor 5WIV
TM6 348 6.58x58 κ receptor 4DJH NOP receptor 5DHG
TM6 349 6.59x59 κ receptor 4DJH ETB receptor 5X93
TM6 350 6.60x60 κ receptor 4DJH BLT1 receptor 5X33
TM6 351 6.61x61 κ receptor 4DJH μ receptor 4DKL
ECL3 352 - - - -
ECL3 353 A2A receptor 3VG9 - -
ECL3 354 A2A receptor 3VG9 - -
ECL3 355 A2A receptor 3VG9 - -
ECL3 356 A2A receptor 3VG9 - -
ECL3 357 - - - -
TM7 358 7.31x30 κ receptor 4DJH - -
TM7 359 7.32x31 κ receptor 4DJH NOP receptor 5DHG
TM7 360 7.33x32 κ receptor 4DJH NTS1 receptor 4BUO
TM7 361 7.34x33 κ receptor 4DJH H1 receptor 3RZE
TM7 362 7.35x34 κ receptor 4DJH κ receptor 4DJH
TM7 363 7.36x35 κ receptor 4DJH 5-HT2C receptor 6BQH
TM7 364 7.37x36 κ receptor 4DJH D2 receptor 6CM4
TM7 365 7.38x37 κ receptor 4DJH A2A receptor 3VG9
TM7 366 7.39x38 κ receptor 4DJH κ receptor 4DJH
TM7 367 7.40x39 κ receptor 4DJH C5a1 receptor 5O9H
TM7 368 7.41x40 κ receptor 4DJH κ receptor 4DJH
TM7 369 7.42x41 κ receptor 4DJH κ receptor 4DJH
TM7 370 7.43x42 κ receptor 4DJH κ receptor 4DJH
TM7 371 7.44x43 κ receptor 4DJH δ receptor 4N6H
TM7 372 7.45x45 κ receptor 4DJH κ receptor 4DJH
TM7 373 7.46x46 κ receptor 4DJH κ receptor 4DJH
TM7 374 7.47x47 κ receptor 4DJH NOP receptor 5DHG
TM7 375 7.48x48 κ receptor 4DJH κ receptor 4DJH
TM7 376 7.49x49 κ receptor 4DJH κ receptor 4DJH
TM7 377 7.50x50 κ receptor 4DJH κ receptor 4DJH
TM7 378 7.51x51 κ receptor 4DJH apelin receptor 5VBL
TM7 379 7.52x52 κ receptor 4DJH 5-HT2C receptor 6BQH
TM7 380 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 381 7.54x54 κ receptor 4DJH Rhodopsin 1GZM
TM7 382 7.55x55 κ receptor 4DJH C5a1 receptor 5O9H
TM7 383 7.56x56 κ receptor 4DJH κ receptor 4DJH
H8 384 8.47x47 κ receptor 4DJH P2Y12 receptor 4NTJ
H8 385 8.48x48 κ receptor 4DJH NOP receptor 5DHG
H8 386 8.49x49 κ receptor 4DJH M4 receptor 5DSG
H8 387 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 388 8.51x51 κ receptor 4DJH CCR5 5UIW
H8 389 8.52x52 κ receptor 4DJH H1 receptor 3RZE
H8 390 8.53x53 κ receptor 4DJH - -
H8 391 8.54x54 κ receptor 4DJH CCR5 5UIW
H8 392 8.55x55 κ receptor 4DJH CCR9 5LWE
H8 393 8.56x56 κ receptor 4DJH M1 receptor 5CXV
H8 394 8.57x57 κ receptor 4DJH - -
H8 395 8.58x58 κ receptor 4DJH - -
H8 396 8.59x59 κ receptor 4DJH - -
C-term 397 κ receptor 4DJH κ receptor 4DJH
C-term 398 - - - -
C-term 399 - - - -
C-term 400 - - - -
C-term 401 - - - -