NPFF2 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.69 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 49%) PDB: 6B73

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 70.2 19.7 10.2
Side-chains 19.4 52.1 28.6

Number of backbone templates: 4
Number of rotamer templates: 33

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6B73
5WS3
5TZR
4UHR
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 141 - - - -
N-term 142 - - - -
N-term 143 κ receptor 6B73 κ receptor 6B73
N-term 144 κ receptor 6B73 κ receptor 6B73
N-term 145 κ receptor 6B73 κ receptor 6B73
TM1 146 1.31x31 κ receptor 6B73 LPA1 receptor 4Z35
TM1 147 1.32x32 κ receptor 6B73 μ receptor 5C1M
TM1 148 1.33x33 κ receptor 6B73 A1 receptor 6D9H
TM1 149 1.34x34 κ receptor 6B73 κ receptor 6B73
TM1 150 1.35x35 κ receptor 6B73 PAF receptor 5ZKP
TM1 151 1.36x36 κ receptor 6B73 A2A receptor 5G53
TM1 152 1.37x37 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 153 1.38x38 κ receptor 6B73 D3 receptor 3PBL
TM1 154 1.39x39 κ receptor 6B73 κ receptor 6B73
TM1 155 1.40x40 κ receptor 6B73 Rhodopsin 5DYS
TM1 156 1.41x41 κ receptor 6B73 5-HT1B receptor 6G79
TM1 157 1.42x42 κ receptor 6B73 5-HT1B receptor 6G79
TM1 158 1.43x43 κ receptor 6B73 κ receptor 6B73
TM1 159 1.44x44 κ receptor 6B73 P2Y12 receptor 4NTJ
TM1 160 1.45x45 κ receptor 6B73 A2A receptor 5G53
TM1 161 1.46x46 κ receptor 6B73 - -
TM1 162 1.47x47 κ receptor 6B73 LPA1 receptor 4Z35
TM1 163 1.48x48 κ receptor 6B73 - -
TM1 164 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 165 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 166 1.51x51 κ receptor 6B73 5-HT2B receptor 5TUD
TM1 167 1.52x52 κ receptor 6B73 AT2 receptor 5UNG
TM1 168 1.53x53 κ receptor 6B73 κ receptor 6B73
TM1 169 1.54x54 κ receptor 6B73 A2A receptor 5G53
TM1 170 1.55x55 κ receptor 6B73 κ receptor 6B73
TM1 171 1.56x56 κ receptor 6B73 LPA6 receptor 5XSZ
TM1 172 1.57x57 κ receptor 6B73 5-HT1B receptor 6G79
TM1 173 1.58x58 κ receptor 6B73 LPA6 receptor 5XSZ
TM1 174 1.59x59 κ receptor 6B73 μ receptor 5C1M
TM1 175 1.60x60 κ receptor 6B73 - -
ICL1 176 12.48x48 - - - -
ICL1 177 12.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL1 178 12.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL1 179 12.51x51 - - - -
TM2 180 2.37x37 κ receptor 6B73 κ receptor 6B73
TM2 181 2.38x38 κ receptor 6B73 M2 receptor 4MQT
TM2 182 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 183 2.40x40 κ receptor 6B73 κ receptor 6B73
TM2 184 2.41x41 κ receptor 6B73 H1 receptor 3RZE
TM2 185 2.42x42 κ receptor 6B73 5-HT2C receptor 6BQG
TM2 186 2.43x43 κ receptor 6B73 κ receptor 6B73
TM2 187 2.44x44 κ receptor 6B73 Rhodopsin 5DYS
TM2 188 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 189 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 190 2.47x47 κ receptor 6B73 κ receptor 6B73
TM2 191 2.48x48 κ receptor 6B73 5-HT2C receptor 6BQG
TM2 192 2.49x49 κ receptor 6B73 LPA6 receptor 5XSZ
TM2 193 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 194 2.51x51 κ receptor 6B73 5-HT1B receptor 6G79
TM2 195 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 196 2.53x53 κ receptor 6B73 κ receptor 6B73
TM2 197 2.54x54 κ receptor 6B73 5-HT2C receptor 6BQG
TM2 198 2.55x55 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 199 2.56x551 OX2 receptor 5WS3 5-HT2B receptor 5TUD
TM2 200 2.57x56 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 201 2.58x57 κ receptor 6B73 κ receptor 6B73
TM2 202 2.59x58 κ receptor 6B73 κ receptor 6B73
TM2 203 2.60x59 κ receptor 6B73 5-HT2B receptor 5TUD
TM2 204 2.61x60 κ receptor 6B73 Rhodopsin 4ZWJ
TM2 205 2.62x61 κ receptor 6B73 5-HT2C receptor 6BQG
TM2 206 2.63x62 κ receptor 6B73 5-HT2C receptor 6BQG
TM2 207 2.64x63 κ receptor 6B73 CB1 receptor 5XRA
TM2 208 2.65x64 κ receptor 6B73 A1 receptor 6D9H
TM2 209 2.66x65 κ receptor 6B73 A1 receptor 6D9H
TM2 210 2.67x66 κ receptor 6B73 M2 receptor 4MQT
TM2 211 2.68x67 OX2 receptor 5WS3 - -
ECL1 212 23.49x49 - - - -
ECL1 213 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 214 23.51x51 OX2 receptor 5WS3 κ receptor 6B73
ECL1 215 23.52x52 - - - -
TM3 216 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 217 3.22x22 κ receptor 6B73 μ receptor 5C1M
TM3 218 3.23x23 κ receptor 6B73 Rhodopsin 5DYS
TM3 219 3.24x24 κ receptor 6B73 AT2 receptor 5UNG
TM3 220 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 221 3.26x26 κ receptor 6B73 κ receptor 6B73
TM3 222 3.27x27 κ receptor 6B73 κ receptor 6B73
TM3 223 3.28x28 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 224 3.29x29 κ receptor 6B73 Rhodopsin 5DYS
TM3 225 3.30x30 κ receptor 6B73 - -
TM3 226 3.31x31 κ receptor 6B73 Y1 receptor 5ZBH
TM3 227 3.32x32 κ receptor 6B73 OX2 receptor 5WS3
TM3 228 3.33x33 κ receptor 6B73 BLT1 receptor 5X33
TM3 229 3.34x34 κ receptor 6B73 A1 receptor 6D9H
TM3 230 3.35x35 κ receptor 6B73 CB1 receptor 5XRA
TM3 231 3.36x36 κ receptor 6B73 β2-adrenoceptor 3SN6
TM3 232 3.37x37 κ receptor 6B73 A2A receptor 4UHR
TM3 233 3.38x38 κ receptor 6B73 5-HT1B receptor 6G79
TM3 234 3.39x39 κ receptor 6B73 κ receptor 6B73
TM3 235 3.40x40 κ receptor 6B73 M2 receptor 4MQT
TM3 236 3.41x41 κ receptor 6B73 κ receptor 6B73
TM3 237 3.42x42 κ receptor 6B73 κ receptor 6B73
TM3 238 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 239 3.44x44 κ receptor 6B73 Rhodopsin 5DYS
TM3 240 3.45x45 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 241 3.46x46 κ receptor 6B73 5-HT1B receptor 6G79
TM3 242 3.47x47 κ receptor 6B73 5-HT1B receptor 6G79
TM3 243 3.48x48 κ receptor 6B73 κ receptor 6B73
TM3 244 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 245 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 246 3.51x51 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 247 3.52x52 κ receptor 6B73 AT2 receptor 5UNG
TM3 248 3.53x53 κ receptor 6B73 M2 receptor 4MQT
TM3 249 3.54x54 κ receptor 6B73 κ receptor 6B73
TM3 250 3.55x55 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 251 3.56x56 κ receptor 6B73 LPA6 receptor 5XSZ
ICL2 252 - - - -
ICL2 253 OX2 receptor 5WS3 - -
ICL2 254 OX2 receptor 5WS3 - -
ICL2 255 OX2 receptor 5WS3 - -
ICL2 256 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL2 257 - - - -
TM4 258 4.38x38 κ receptor 6B73 κ receptor 6B73
TM4 259 4.39x39 κ receptor 6B73 - -
TM4 260 4.40x40 κ receptor 6B73 5-HT1B receptor 6G79
TM4 261 4.41x41 κ receptor 6B73 5-HT2B receptor 5TUD
TM4 262 4.42x42 κ receptor 6B73 κ receptor 6B73
TM4 263 4.43x43 κ receptor 6B73 5-HT2B receptor 5TUD
TM4 264 4.44x44 κ receptor 6B73 5-HT1B receptor 6G79
TM4 265 4.45x45 κ receptor 6B73 κ receptor 6B73
TM4 266 4.46x46 κ receptor 6B73 5-HT1B receptor 6G79
TM4 267 4.47x47 κ receptor 6B73 - -
TM4 268 4.48x48 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 269 4.49x49 κ receptor 6B73 κ receptor 6B73
TM4 270 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 271 4.51x51 κ receptor 6B73 5-HT1B receptor 6G79
TM4 272 4.52x52 κ receptor 6B73 κ receptor 6B73
TM4 273 4.53x53 κ receptor 6B73 Rhodopsin 5DYS
TM4 274 4.54x54 κ receptor 6B73 5-HT1B receptor 6G79
TM4 275 4.55x55 κ receptor 6B73 D2 receptor 6CM4
TM4 276 4.56x56 κ receptor 6B73 μ receptor 5C1M
TM4 277 4.57x57 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 278 4.58x59 OX2 receptor 5WS3 κ receptor 4DJH
TM4 279 4.59x60 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 280 4.60x61 κ receptor 6B73 C5a1 receptor 5O9H
TM4 281 4.61x62 κ receptor 6B73 Rhodopsin 4ZWJ
TM4 282 4.62x63 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 283 4.63x64 κ receptor 6B73 - -
TM4 284 4.64x65 OX2 receptor 5WS3 - -
ECL2 285 - - - -
ECL2 286 FFA1 receptor 5TZR - -
ECL2 287 FFA1 receptor 5TZR - -
ECL2 288 FFA1 receptor 5TZR - -
ECL2 289 FFA1 receptor 5TZR - -
ECL2 290 FFA1 receptor 5TZR - -
ECL2 291 FFA1 receptor 5TZR - -
ECL2 292 FFA1 receptor 5TZR - -
ECL2 293 FFA1 receptor 5TZR - -
ECL2 294 FFA1 receptor 5TZR - -
ECL2 295 FFA1 receptor 5TZR - -
ECL2 296 FFA1 receptor 5TZR FFA1 receptor 5TZR
ECL2 297 FFA1 receptor 5TZR - -
ECL2 298 FFA1 receptor 5TZR - -
ECL2 299 FFA1 receptor 5TZR - -
ECL2 300 FFA1 receptor 5TZR - -
ECL2 301 FFA1 receptor 5TZR - -
ECL2 302 FFA1 receptor 5TZR - -
ECL2 303 FFA1 receptor 5TZR - -
ECL2 304 FFA1 receptor 5TZR - -
ECL2 305 FFA1 receptor 5TZR - -
ECL2 306 FFA1 receptor 5TZR - -
ECL2 307 - - - -
ECL2 308 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 309 45.51x51 κ receptor 6B73 D4 receptor 5WIV
ECL2 310 45.52x52 κ receptor 6B73 OX2 receptor 5WS3
ECL2 311 - - - -
ECL2 312 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL2 313 OX2 receptor 5WS3 - -
ECL2 314 OX2 receptor 5WS3 - -
ECL2 315 - - - -
TM5 316 5.33x34 κ receptor 6B73 - -
TM5 317 5.34x35 κ receptor 6B73 - -
TM5 318 5.35x36 κ receptor 6B73 Y1 receptor 5ZBH
TM5 319 5.36x37 κ receptor 6B73 NTS1 receptor 5T04
TM5 320 5.37x38 κ receptor 6B73 US28 4XT1
TM5 321 5.38x39 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 322 5.39x40 κ receptor 6B73 5-HT1B receptor 6G79
TM5 323 5.40x41 κ receptor 6B73 Y1 receptor 5ZBH
TM5 324 5.41x42 κ receptor 6B73 NTS1 receptor 5T04
TM5 325 5.42x43 κ receptor 6B73 US28 4XT1
TM5 326 5.43x44 κ receptor 6B73 κ receptor 6B73
TM5 327 5.44x45 κ receptor 6B73 - -
TM5 328 5.45x46 κ receptor 6B73 - -
TM5 329 5.46x461 κ receptor 6B73 - -
TM5 330 5.47x47 κ receptor 6B73 OX2 receptor 5WS3
TM5 331 5.48x48 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 332 5.49x49 κ receptor 6B73 OX2 receptor 5WS3
TM5 333 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 334 5.51x51 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 335 5.52x52 κ receptor 6B73 US28 4XT1
TM5 336 5.53x53 κ receptor 6B73 5-HT1B receptor 6G79
TM5 337 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 338 5.55x55 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 339 5.56x56 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 340 5.57x57 κ receptor 6B73 - -
TM5 341 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 342 5.59x59 κ receptor 6B73 μ receptor 5C1M
TM5 343 5.60x60 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 344 5.61x61 κ receptor 6B73 5-HT1B receptor 6G79
TM5 345 5.62x62 κ receptor 6B73 - -
TM5 346 5.63x63 κ receptor 6B73 Y1 receptor 5ZBH
TM5 347 5.64x64 κ receptor 6B73 - -
TM5 348 5.65x65 κ receptor 6B73 κ receptor 6B73
TM5 349 5.66x66 κ receptor 6B73 - -
TM5 350 5.67x67 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 351 5.68x68 A2A receptor 4UHR Rhodopsin 5DYS
TM5 352 5.69x69 A2A receptor 4UHR 5-HT2C receptor 6BQG
TM5 353 5.70x70 A2A receptor 4UHR P2Y12 receptor 4NTJ
TM5 354 5.71x71 A2A receptor 4UHR - -
TM5 355 5.72x72 A2A receptor 4UHR - -
TM5 356 5.73x73 A2A receptor 4UHR - -
ICL3 357 - - - -
ICL3 358 - - - -
ICL3 359 - - - -
ICL3 360 - - - -
ICL3 361 - - - -
ICL3 362 - - - -
ICL3 363 - - - -
ICL3 364 - - - -
TM6 365 6.24x24 κ receptor 6B73 - -
TM6 366 6.25x25 κ receptor 6B73 - -
TM6 367 6.26x26 κ receptor 6B73 - -
TM6 368 6.27x27 κ receptor 6B73 Y1 receptor 5ZBH
TM6 369 6.28x28 κ receptor 6B73 μ receptor 6DDF
TM6 370 6.29x29 κ receptor 6B73 A2A receptor 5G53
TM6 371 6.30x30 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 372 6.31x31 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 373 6.32x32 κ receptor 6B73 5-HT1B receptor 6G79
TM6 374 6.33x33 κ receptor 6B73 κ receptor 6B73
TM6 375 6.34x34 κ receptor 6B73 - -
TM6 376 6.35x35 κ receptor 6B73 5-HT1B receptor 6G79
TM6 377 6.36x36 κ receptor 6B73 μ receptor 5C1M
TM6 378 6.37x37 κ receptor 6B73 5-HT1B receptor 6G79
TM6 379 6.38x38 κ receptor 6B73 κ receptor 6B73
TM6 380 6.39x39 κ receptor 6B73 5-HT1B receptor 6G79
TM6 381 6.40x40 κ receptor 6B73 κ receptor 6B73
TM6 382 6.41x41 κ receptor 6B73 D2 receptor 6CM4
TM6 383 6.42x42 κ receptor 6B73 M2 receptor 4MQT
TM6 384 6.43x43 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 385 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 386 6.45x45 κ receptor 6B73 μ receptor 5C1M
TM6 387 6.46x46 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 388 6.47x47 κ receptor 6B73 A1 receptor 6D9H
TM6 389 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 390 6.49x49 κ receptor 6B73 5-HT1B receptor 6G79
TM6 391 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 392 6.51x51 κ receptor 6B73 A2A receptor 5G53
TM6 393 6.52x52 κ receptor 6B73 - -
TM6 394 6.53x53 κ receptor 6B73 - -
TM6 395 6.54x54 κ receptor 6B73 A1 receptor 6D9H
TM6 396 6.55x55 κ receptor 6B73 CB1 receptor 5XRA
TM6 397 6.56x56 κ receptor 6B73 H1 receptor 3RZE
TM6 398 6.57x57 κ receptor 6B73 5-HT2C receptor 6BQG
TM6 399 6.58x58 κ receptor 6B73 5-HT2C receptor 6BQG
TM6 400 6.59x59 κ receptor 6B73 Y1 receptor 5ZBH
TM6 401 6.60x60 κ receptor 6B73 NTS1 receptor 5T04
TM6 402 6.61x61 κ receptor 6B73 - -
ECL3 403 - - - -
ECL3 404 - - - -
ECL3 405 - - - -
ECL3 406 - - - -
ECL3 407 - - - -
ECL3 408 - - - -
ECL3 409 - - - -
TM7 410 7.28x27 κ receptor 6B73 - -
TM7 411 7.29x28 κ receptor 6B73 - -
TM7 412 7.30x29 κ receptor 6B73 AT1 receptor 4ZUD
TM7 413 7.31x30 κ receptor 6B73 - -
TM7 414 7.32x31 κ receptor 6B73 - -
TM7 415 7.33x32 κ receptor 6B73 NTS1 receptor 5T04
TM7 416 7.34x33 κ receptor 6B73 5-HT1B receptor 6G79
TM7 417 7.35x34 κ receptor 6B73 κ receptor 6B73
TM7 418 7.36x35 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 419 7.37x36 κ receptor 6B73 κ receptor 6B73
TM7 420 7.38x37 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 421 7.39x38 κ receptor 6B73 OX2 receptor 5WS3
TM7 422 7.40x39 κ receptor 6B73 5-HT1B receptor 6G79
TM7 423 7.41x40 κ receptor 6B73 κ receptor 6B73
TM7 424 7.42x41 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 425 7.43x42 κ receptor 6B73 AT2 receptor 5UNG
TM7 426 7.44x43 κ receptor 6B73 A1 receptor 6D9H
TM7 427 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 428 7.46x46 κ receptor 6B73 κ receptor 6B73
TM7 429 7.47x47 κ receptor 6B73 κ receptor 6B73
TM7 430 7.48x48 κ receptor 6B73 5-HT2B receptor 5TUD
TM7 431 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 432 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 433 7.51x51 κ receptor 6B73 5-HT1B receptor 6G79
TM7 434 7.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 435 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 436 7.54x54 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 437 7.55x55 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 438 7.56x56 OX2 receptor 5WS3 5-HT2C receptor 6BQG
H8 439 8.47x47 OX2 receptor 5WS3 5-HT1B receptor 6G79
H8 440 8.48x48 OX2 receptor 5WS3 μ receptor 4DKL
H8 441 8.49x49 OX2 receptor 5WS3 Y1 receptor 5ZBH
H8 442 8.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 443 8.51x51 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 444 8.52x52 OX2 receptor 5WS3 5-HT2C receptor 6BQG
H8 445 8.53x53 OX2 receptor 5WS3 - -
H8 446 8.54x54 OX2 receptor 5WS3 5-HT1B receptor 6G79
H8 447 8.55x55 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
H8 448 8.56x56 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
H8 449 8.57x57 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 450 8.58x58 OX2 receptor 5WS3 OX2 receptor 5WS3
C-term 451 - - - -
C-term 452 - - - -
C-term 453 - - - -
C-term 454 - - - -
C-term 455 - - - -