grm5_human
NAME
5CGC
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
grm5_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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V
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L
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L
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L
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I
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L
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S
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V
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L
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10 |
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L
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L
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K
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20 |
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Q
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R
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30 |
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M
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P
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G
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D
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I
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I
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40 |
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F
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H
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H
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50 |
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K
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H
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K
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60 |
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R
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E
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Q
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Y
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G
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I
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70 |
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A
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M
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L
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H
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T
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L
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N
|
80 |
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S
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D
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P
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T
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L
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L
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N
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I
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T
|
90 |
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L
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C
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100 |
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H
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A
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A
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L
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110 |
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D
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S
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L
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I
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S
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S
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120 |
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E
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E
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E
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E
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G
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L
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V
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C
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V
|
130 |
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D
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S
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S
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S
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F
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|
140 |
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K
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P
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I
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V
|
G
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V
|
I
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|
G
|
150 |
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S
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S
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S
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V
|
A
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I
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Q
|
V
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Q
|
N
|
160 |
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L
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L
|
Q
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L
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F
|
N
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I
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P
|
Q
|
I
|
170 |
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A
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Y
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S
|
A
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T
|
S
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M
|
D
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L
|
S
|
180 |
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D
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K
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T
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L
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F
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K
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Y
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M
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|
190 |
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V
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V
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P
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|
A
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Q
|
A
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|
200 |
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A
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M
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V
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D
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V
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K
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|
Y
|
N
|
210 |
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W
|
T
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Y
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V
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S
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A
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|
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|
220 |
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G
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N
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Y
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G
|
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|
S
|
G
|
M
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|
A
|
230 |
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240 |
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K
|
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|
250 |
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N
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A
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K
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L
|
260 |
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K
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L
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270 |
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C
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C
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|
280 |
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M
|
T
|
V
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R
|
G
|
L
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L
|
M
|
A
|
M
|
290 |
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R
|
R
|
L
|
G
|
L
|
A
|
G
|
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|
F
|
L
|
300 |
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|
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|
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L
|
L
|
G
|
S
|
D
|
G
|
W
|
A
|
D
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R
|
310 |
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Y
|
D
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V
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T
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D
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Y
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|
320 |
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V
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G
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330 |
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D
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K
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W
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D
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Y
|
340 |
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Y
|
L
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K
|
L
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P
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N
|
H
|
350 |
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R
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N
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P
|
W
|
F
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Q
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W
|
Q
|
360 |
|
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F
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|
F
|
370 |
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P
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N
|
S
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K
|
Y
|
N
|
K
|
T
|
380 |
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|
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|
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|
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C
|
N
|
S
|
S
|
L
|
T
|
L
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K
|
T
|
H
|
390 |
|
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H
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V
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M
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G
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F
|
V
|
400 |
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I
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N
|
A
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I
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Y
|
S
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M
|
A
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Y
|
G
|
410 |
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L
|
H
|
N
|
M
|
Q
|
M
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S
|
L
|
C
|
P
|
420 |
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G
|
Y
|
A
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G
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L
|
C
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D
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A
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M
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K
|
430 |
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D
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K
|
L
|
L
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|
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|
440 |
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L
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M
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K
|
T
|
N
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F
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V
|
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|
450 |
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G
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D
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T
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I
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L
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F
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N
|
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|
460 |
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|
S
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P
|
G
|
R
|
Y
|
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M
|
N
|
470 |
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F
|
K
|
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M
|
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|
K
|
D
|
Y
|
F
|
D
|
480 |
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Y
|
I
|
N
|
V
|
G
|
S
|
W
|
D
|
N
|
G
|
490 |
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E
|
L
|
K
|
M
|
D
|
D
|
D
|
E
|
V
|
W
|
500 |
|
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S
|
K
|
K
|
S
|
N
|
I
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I
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R
|
S
|
V
|
510 |
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C
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|
C
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K
|
G
|
Q
|
I
|
520 |
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K
|
V
|
I
|
R
|
K
|
G
|
E
|
V
|
S
|
C
|
530 |
|
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|
|
C
|
W
|
T
|
C
|
T
|
P
|
C
|
K
|
E
|
N
|
540 |
|
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|
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|
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E
|
Y
|
V
|
F
|
D
|
E
|
Y
|
T
|
C
|
K
|
550 |
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|
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|
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|
|
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A
|
C
|
Q
|
L
|
G
|
S
|
W
|
P
|
T
|
D
|
560 |
|
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||
D
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L
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T
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G
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C
|
D
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L
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I
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P
|
V
|
570 |
|
|||||||||
TM1 | |||||||||
Q
|
Y
|
L
|
R
|
W
|
G
|
D
|
P
|
E
|
P
|
580 |
I
|
A
|
A
|
V
|
V
|
F
|
A
|
C
|
L
|
G
|
590 |
L
|
L
|
A
|
T
|
L
|
F
|
V
|
T
|
V
|
V
|
600 |
ICL1 | |||||||||
F
|
I
|
I
|
Y
|
R
|
D
|
T
|
P
|
V
|
V
|
610 |
TM2 | |||||||||
K
|
S
|
S
|
S
|
R
|
E
|
L
|
C
|
Y
|
I
|
620 |
I
|
L
|
A
|
G
|
I
|
C
|
L
|
G
|
Y
|
L
|
630 |
ECL1 | |||||||||
C
|
T
|
F
|
C
|
L
|
I
|
A
|
K
|
P
|
K
|
640 |
TM3 | |||||||||
Q
|
I
|
Y
|
C
|
Y
|
L
|
Q
|
R
|
I
|
G
|
650 |
I
|
G
|
L
|
S
|
P
|
A
|
M
|
S
|
Y
|
S
|
660 |
|
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||||||||
A
|
L
|
V
|
T
|
K
|
T
|
N
|
R
|
I
|
A
|
670 |
|
|
|
|||||||
ICL2 | |||||||||
R
|
I
|
L
|
A
|
G
|
S
|
K
|
K
|
K
|
I
|
680 |
C
|
T
|
K
|
K
|
P
|
R
|
F
|
M
|
S
|
A
|
690 |
TM4 | |||||||||
C
|
A
|
Q
|
L
|
V
|
I
|
A
|
F
|
I
|
L
|
700 |
I
|
C
|
I
|
Q
|
L
|
G
|
I
|
I
|
V
|
A
|
710 |
ECL2 | |||||||||
L
|
F
|
I
|
M
|
E
|
P
|
P
|
D
|
I
|
M
|
720 |
H
|
D
|
Y
|
P
|
S
|
I
|
R
|
E
|
V
|
Y
|
730 |
TM5 | |||||||||
L
|
I
|
C
|
N
|
T
|
T
|
N
|
L
|
G
|
V
|
740 |
|
|||||||||
V
|
T
|
P
|
L
|
G
|
Y
|
N
|
G
|
L
|
L
|
750 |
|
|||||||||
I
|
L
|
S
|
C
|
T
|
F
|
Y
|
A
|
F
|
K
|
760 |
ICL3 | |||||||||
T
|
R
|
N
|
V
|