agtr2_human
NAME
6JOD
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
agtr2_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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K
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G
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N
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S
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T
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L
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A
|
T
|
T
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10 |
|
|
|
|
|
|
|
|
|
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S
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K
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N
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I
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T
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S
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G
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L
|
H
|
F
|
20 |
|
|
|
|
|
|
|
|
|
|
G
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L
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V
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N
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I
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S
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G
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N
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N
|
E
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30 |
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|
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||||||
S
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T
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L
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N
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C
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S
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Q
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K
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P
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S
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40 |
TM1 | |||||||||
D
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K
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H
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L
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D
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A
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I
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P
|
I
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L
|
50 |
Y
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Y
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I
|
I
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F
|
V
|
I
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G
|
F
|
L
|
60 |
V
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N
|
I
|
V
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V
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V
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T
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L
|
F
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C
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70 |
ICL1 | TM2 | ||||||||
C
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Q
|
K
|
G
|
P
|
K
|
K
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V
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S
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S
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80 |
I
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Y
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I
|
F
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N
|
L
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A
|
V
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A
|
D
|
90 |
L
|
L
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L
|
L
|
A
|
T
|
L
|
P
|
L
|
W
|
100 |
A
|
T
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Y
|
Y
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S
|
Y
|
R
|
Y
|
D
|
W
|
110 |
ECL1 | TM3 | ||||||||
L
|
F
|
G
|
P
|
V
|
M
|
C
|
K
|
V
|
F
|
120 |
G
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S
|
F
|
L
|
T
|
L
|
N
|
M
|
F
|
A
|
130 |
S
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I
|
F
|
F
|
I
|
T
|
C
|
M
|
S
|
V
|
140 |
D
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R
|
Y
|
Q
|
S
|
V
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I
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Y
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P
|
F
|
150 |
ICL2 | TM4 | ||||||||
L
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S
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Q
|
R
|
R
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N
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P
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W
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Q
|
A
|
160 |
S
|
Y
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I
|
V
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P
|
L
|
V
|
W
|
C
|
M
|
170 |
A
|
C
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L
|
S
|
S
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L
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P
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T
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F
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Y
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180 |
ECL2 | |||||||||
F
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R
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D
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V
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R
|
T
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I
|
E
|
Y
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L
|
190 |
G
|
V
|
N
|
A
|
C
|
I
|
M
|
A
|
F
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P
|
200 |
TM5 | |||||||||
P
|
E
|
K
|
Y
|
A
|
Q
|
W
|
S
|
A
|
G
|
210 |
I
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A
|
L
|
M
|
K
|
N
|
I
|
L
|
G
|
F
|
220 |
I
|
I
|
P
|
L
|
I
|
F
|
I
|
A
|
T
|
C
|
230 |
Y
|
F
|
G
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I
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R
|
K
|
H
|
L
|
L
|
K
|
240 |
ICL3 | TM6 | ||||||||
T
|
N
|
S
|
Y
|
G
|
K
|
N
|
R
|
I
|
T
|
250 |
R
|
D
|
Q
|
V
|
L
|
K
|
M
|
A
|
A
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A
|
260 |
V
|
V
|
L
|
A
|
F
|
I
|
I
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C
|
W
|
L
|
270 |
P
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F
|
H
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V
|
L
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T
|
F
|
L
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D
|
A
|
280 |
ECL3 | |||||||||
L
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A
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W
|
M
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G
|
V
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I
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N
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S
|
C
|
290 |
TM7 | |||||||||
E
|
V
|
I
|
A
|
V
|
I
|
D
|
L
|
A
|
L
|
300 |
P
|
F
|
A
|
I
|
L
|
L
|
G
|
F
|
T
|
N
|
310 |
S
|
C
|
V
|
N
|
P
|
F
|
L
|
Y
|
C
|
F
|
320 |
H8 | |||||||||
V
|
G
|
N
|
R
|
F
|
Q
|
Q
|
K
|
L
|
R
|
330 |
S
|
V
|
F
|
R
|
V
|
P
|
I
|
T
|
W
|
L
|
340 |
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||||||
C-term | |||||||||
Q
|
G
|
K
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R
|
E
|
S
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M
|
S
|
C
|
R
|
350 |
|
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|
|
|
|
|
|
|
|
K
|
S
|
S
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S
|
L
|
R
|
E
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M
|
E
|
T
|
360 |
|
|
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F
|
V
|
S
|
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|||||||||
N-term | |||||||||
|
C
|
S
|
Q
|
K
|
P
|
S
|
D
|
K
|
H
|
43 |
TM1 | |||||||||
L
|
D
|
A
|
I
|
P
|
I
|
L
|
Y
|
Y
|
I
|
53 |
I
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F
|
V
|
I
|
G
|
F
|
L
|
V
|
N
|
I
|
63 |
V
|
V
|
V
|
T
|
L
|
F
|
C
|
C
|
Q
|
K
|
73 |
ICL1 | TM2 | ||||||||
G
|
P
|
K
|
K
|
V
|
S
|
S
|
I
|
Y
|
I
|
83 |
F
|
N
|
L
|
A
|
V
|
A
|
D
|
L
|
L
|
L
|
93 |
L
|
A
|
T
|
L
|
P
|
L
|
W
|
A
|
T
|
Y
|
103 |
ECL1 | |||||||||
Y
|
S
|
Y
|
R
|
Y
|
D
|
W
|
L
|
F
|
G
|
113 |
TM3 | |||||||||
P
|
V
|
M
|
C
|
K
|
V
|
F
|
G
|
S
|
F
|
123 |
L
|
T
|
L
|
N
|
M
|
F
|
A
|
S
|
I
|
F
|
133 |
F
|
I
|
T
|
C
|
M
|
S
|
V
|
D
|
R
|
Y
|
143 |
ICL2 | |||||||||
Q
|
S
|
V
|
I
|
Y
|
P
|
F
|
L
|
S
|
Q
|
153 |
TM4 | |||||||||
R
|
R
|
N
|
P
|
W
|
Q
|
A
|
S
|
Y
|
I
|
163 |
V
|
P
|
L
|
V
|
W
|
C
|
M
|
A
|
C
|
L
|
173 |
S
|
S
|
L
|
P
|
T
|
F
|
Y
|
F
|
R
|
D
|
183 |
ECL2 | |||||||||
V
|
R
|
T
|
I
|
E
|
Y
|
L
|
G
|
V
|
N
|
193 |
A
|
C
|
I
|
M
|
A
|
F
|
P
|
P
|
E
|
K
|
203 |
TM5 | |||||||||
Y
|
A
|
Q
|
W
|
S
|
A
|
G
|
I
|
A
|
L
|
213 |
M
|
K
|
N
|
I
|
L
|
G
|
F
|
I
|
I
|
P
|
223 |
L
|
I
|
F
|
I
|
A
|
T
|
C
|
Y
|
F
|
G
|
233 |
I
|
R
|
K
|
H
|
L
|
L
|
K
|
T
|
N
|
S
|
243 |
ICL3 | TM6 | ||||||||
Y
|
G
|
K
|
N
|
R
|
I
|
T
|
R
|
D
|
Q
|
253 |
V
|
L
|
K
|
M
|
A
|
A
|
A
|
V
|
V
|
L
|
263 |
A
|
F
|
I
|
I
|
C
|
W
|
L
|
P
|
F
|
H
|
273 |
V
|
L
|
T
|
F
|
L
|
D
|
A
|
L
|
A
|
W
|
283 |
ECL3 | TM7 | ||||||||
M
|
G
|
V
|
I
|
N
|
S
|
C
|
E
|
V
|
I
|
293 |
A
|
V
|
I
|
D
|
L
|
A
|
L
|
P
|
F
|
A
|
303 |
I
|
L
|
L
|
G
|
F
|
T
|
N
|
S
|
C
|
V
|
313 |
H8 | |||||||||
N
|
P
|
F
|
L
|
Y
|
C
|
F
|
V
|
G
|
N
|
323 |
R
|
F
|
Q
|
Q
|
K
|
L
|
R
|
S
|
V
|
F
|
333 |
C-term | |||||||||
R
|
V
|
P
|
I
|
T
|
W
|
L
|
Q
|
G
|
K
|
343 |
|
|||
R
|
E
|
S
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
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