pth1r_human
NAME
6NBF
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
pth1r_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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G
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T
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A
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R
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I
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A
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P
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G
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L
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10 |
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L
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L
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L
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C
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C
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P
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20 |
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S
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A
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Y
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A
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V
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D
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A
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D
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D
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30 |
V
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M
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E
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L
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40 |
L
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A
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A
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50 |
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60 |
S
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W
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|
70 |
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80 |
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|
90 |
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100 |
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110 |
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120 |
G
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130 |
C
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N
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H
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140 |
K
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Y
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R
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C
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150 |
N
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160 |
N
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R
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A
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N
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Y
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S
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E
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C
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170 |
TM1 | |||||||||
V
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K
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F
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L
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N
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180 |
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190 |
Y
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L
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A
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200 |
S
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L
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V
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A
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V
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L
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I
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L
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A
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210 |
ICL1 | TM2 | ||||||||
Y
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F
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R
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R
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L
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H
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C
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T
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N
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220 |
Y
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M
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F
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L
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230 |
M
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K
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240 |
D
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A
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Y
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S
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G
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A
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T
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L
|
250 |
ECL1 | |||||||||
D
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E
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A
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E
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R
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L
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T
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E
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E
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E
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260 |
L
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R
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A
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I
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A
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Q
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A
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P
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P
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P
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270 |
TM3 | |||||||||
P
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A
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T
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A
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A
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A
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G
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Y
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A
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G
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280 |
C
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V
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A
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V
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T
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F
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F
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L
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Y
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290 |
F
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A
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N
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Y
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Y
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W
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I
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L
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300 |
V
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G
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L
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Y
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L
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H
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L
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I
|
310 |
ICL2 | TM4 | ||||||||
F
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M
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A
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F
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F
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S
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E
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K
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K
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Y
|
320 |
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330 |
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340 |
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N
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T
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G
|
350 |
ECL2 | TM5 | ||||||||
C
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W
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D
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L
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S
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G
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N
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K
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K
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360 |
W
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370 |
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380 |
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R
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V
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A
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T
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K
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L
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R
|
390 |
ICL3 | TM6 | ||||||||
E
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T
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N
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A
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G
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R
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C
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D
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T
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R
|
400 |
Q
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Q
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Y
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K
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L
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K
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T
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410 |
L
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M
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V
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H
|
420 |
Y
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I
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V
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F
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M
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A
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T
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P
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Y
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T
|
430 |
ECL3 | TM7 | ||||||||
E
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V
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S
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G
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T
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L
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W
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Q
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V
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Q
|
440 |
M
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H
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Y
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E
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M
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L
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F
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N
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S
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F
|
450 |
Q
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F
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F
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V
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A
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I
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I
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Y
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C
|
460 |
H8 | |||||||||
F
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C
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N
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G
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E
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V
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Q
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A
|
E
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I
|
470 |
K
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K
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S
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W
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S
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R
|
W
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T
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L
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A
|
480 |
L
|
D
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F
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K
|
R
|
K
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A
|
R
|
S
|
G
|
490 |
C-term | |||||||||
S
|
S
|
S
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Y
|
S
|
Y
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G
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P
|
M
|
V
|
500 |
|
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||
S
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H
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T
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S
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V
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T
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N
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V
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G
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P
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510 |
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V
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L
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L
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P
|
520 |
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R
|
L
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L
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P
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T
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A
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T
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N
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G
|
530 |
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H
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Q
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A
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K
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P
|
540 |
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G
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P
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A
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L
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E
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T
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L
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T
|
550 |
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T
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P
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P
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A
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M
|
A
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A
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P
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K
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D
|
560 |
|
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|
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|
|
D
|
G
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F
|
L
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N
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G
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S
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C
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S
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G
|
570 |
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L
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D
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E
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E
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A
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S
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G
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P
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R
|
580 |
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P
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P
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A
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L
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L
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Q
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E
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E
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W
|
E
|
590 |
|
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T
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V
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M
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|||||||||
N-term | |||||||||
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D
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A
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D
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D
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V
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M
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T
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K
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E
|
35 |
E
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Q
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I
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F
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L
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L
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H
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R
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A
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Q
|
45 |
A
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C
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K
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R
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L
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K
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V
|
55 |
L
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Q
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R
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P
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A
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S
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I
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M
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E
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S
|
65 |
D
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K
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G
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W
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T
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S
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A
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S
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T
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S
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75 |
G
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K
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P
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R
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K
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D
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K
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A
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S
|
G
|
85 |
K
|
L
|
Y
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P
|
E
|
S
|
E
|
E
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D
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K
|
95 |
E
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A
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P
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T
|
G
|
S
|
R
|
Y
|
R
|
G
|
105 |
R
|
P
|
C
|
L
|
P
|
E
|
W
|
D
|
H
|
I
|
115 |
L
|
C
|
W
|
P
|
L
|
G
|
A
|
P
|
G
|
E
|
125 |
V
|
V
|
A
|
V
|
P
|
C
|
P
|
D
|
Y
|
I
|
135 |
Y
|
D
|
F
|
N
|
H
|
K
|
G
|
H
|
A
|
Y
|
145 |
R
|
R
|
C
|
D
|
R
|
N
|
G
|
S
|
W
|
E
|
155 |
L
|
V
|
P
|
G
|
H
|
N
|
R
|
T
|
W
|
A
|
165 |
TM1 | |||||||||
N
|
Y
|
S
|
E
|
C
|
V
|
K
|
F
|
L
|
T
|
175 |
N
|
E
|
T
|
R
|
E
|
R
|
E
|
V
|
F
|
D
|
185 |
R
|
L
|
G
|
M
|
I
|
Y
|
T
|
V
|
G
|
Y
|
195 |
S
|
V
|
S
|
L
|
A
|
S
|
L
|
T
|
V
|
A
|
205 |