oprm_mouse
NAME
9BQJ
ORGANISM
Mouse (Mus musculus)
PROTEIN NAME
oprm_mouse
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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D
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S
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S
|
A
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G
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P
|
G
|
N
|
I
|
10 |
S
|
D
|
C
|
S
|
D
|
P
|
L
|
A
|
P
|
A
|
20 |
S
|
C
|
S
|
P
|
A
|
P
|
G
|
S
|
W
|
L
|
30 |
N
|
L
|
S
|
H
|
V
|
D
|
G
|
N
|
Q
|
S
|
40 |
D
|
P
|
C
|
G
|
P
|
N
|
R
|
T
|
G
|
L
|
50 |
G
|
G
|
S
|
H
|
S
|
L
|
C
|
P
|
Q
|
T
|
60 |
TM1 | |||||||||
G
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S
|
P
|
S
|
M
|
V
|
T
|
A
|
I
|
T
|
70 |
I
|
M
|
A
|
L
|
Y
|
S
|
I
|
V
|
C
|
V
|
80 |
V
|
G
|
L
|
F
|
G
|
N
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F
|
L
|
V
|
M
|
90 |
ICL1 | |||||||||
Y
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V
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I
|
V
|
R
|
Y
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T
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K
|
M
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K
|
100 |
TM2 | |||||||||
T
|
A
|
T
|
N
|
I
|
Y
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I
|
F
|
N
|
L
|
110 |
A
|
L
|
A
|
D
|
A
|
L
|
A
|
T
|
S
|
T
|
120 |
L
|
P
|
F
|
Q
|
S
|
V
|
N
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Y
|
L
|
M
|
130 |
ECL1 | TM3 | ||||||||
G
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T
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W
|
P
|
F
|
G
|
N
|
I
|
L
|
C
|
140 |
K
|
I
|
V
|
I
|
S
|
I
|
D
|
Y
|
Y
|
N
|
150 |
M
|
F
|
T
|
S
|
I
|
F
|
T
|
L
|
C
|
T
|
160 |
M
|
S
|
V
|
D
|
R
|
Y
|
I
|
A
|
V
|
C
|
170 |
ICL2 | |||||||||
H
|
P
|
V
|
K
|
A
|
L
|
D
|
F
|
R
|
T
|
180 |
TM4 | |||||||||
P
|
R
|
N
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A
|
K
|
I
|
V
|
N
|
V
|
C
|
190 |
N
|
W
|
I
|
L
|
S
|
S
|
A
|
I
|
G
|
L
|
200 |
ECL2 | |||||||||
P
|
V
|
M
|
F
|
M
|
A
|
T
|
T
|
K
|
Y
|
210 |
R
|
Q
|
G
|
S
|
I
|
D
|
C
|
T
|
L
|
T
|
220 |
TM5 | |||||||||
F
|
S
|
H
|
P
|
T
|
W
|
Y
|
W
|
E
|
N
|
230 |
L
|
L
|
K
|
I
|
C
|
V
|
F
|
I
|
F
|
A
|
240 |
F
|
I
|
M
|
P
|
V
|
L
|
I
|
I
|
T
|
V
|
250 |
C
|
Y
|
G
|
L
|
M
|
I
|
L
|
R
|
L
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K
|
260 |
ICL3 | TM6 | ||||||||
S
|
V
|
R
|
M
|
L
|
S
|
G
|
S
|
K
|
E
|
270 |
K
|
D
|
R
|
N
|
L
|
R
|
R
|
I
|
T
|
R
|
280 |
M
|
V
|
L
|
V
|
V
|
V
|
A
|
V
|
F
|
I
|
290 |
V
|
C
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W
|
T
|
P
|
I
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H
|
I
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Y
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V
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300 |
ECL3 | |||||||||
I
|
I
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K
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A
|
L
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I
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T
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I
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P
|
E
|
310 |
TM7 | |||||||||
T
|
T
|
F
|
Q
|
T
|
V
|
S
|
W
|
H
|
F
|
320 |
C
|
I
|
A
|
L
|
G
|
Y
|
T
|
N
|
S
|
C
|
330 |
L
|
N
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P
|
V
|
L
|
Y
|
A
|
F
|
L
|
D
|
340 |
H8 | |||||||||
E
|
N
|
F
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K
|
R
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C
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F
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R
|
E
|
F
|
350 |
|
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||||||||
C-term | |||||||||
C
|
I
|
P
|
T
|
S
|
S
|
T
|
I
|
E
|
Q
|
360 |
|
|
|
|
|
|
|
|
|
|
Q
|
N
|
S
|
A
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R
|
I
|
R
|
Q
|
N
|
T
|
370 |
|
|
|
|
|
|
|
|
|
|
R
|
E
|
H
|
P
|
S
|
T
|
A
|
N
|
T
|
V
|
380 |
|
|
|
|
|
|
|
|
|
|
D
|
R
|
T
|
N
|
H
|
Q
|
L
|
E
|
N
|
L
|
390 |
|
|
|
|
|
|
|
|
E
|
A
|
E
|
T
|
A
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P
|
L
|
P
|
|
|||||||||
N-term | |||||||||
|
N
|
I
|
S
|
D
|
C
|
S
|
D
|
P
|
L
|
17 |
A
|
P
|
A
|
S
|
C
|
S
|
P
|
A
|
P
|
G
|
27 |
S
|
W
|
L
|
N
|
L
|
S
|
H
|
V
|
D
|
G
|
37 |
N
|
Q
|
S
|
D
|
P
|
C
|
G
|
P
|
N
|
R
|
47 |
T
|
G
|
L
|
G
|
G
|
S
|
H
|
S
|
L
|
C
|
57 |
TM1 | |||||||||
P
|
Q
|
T
|
G
|
S
|
P
|
S
|
M
|
V
|
T
|
67 |
A
|
I
|
T
|
I
|
M
|
A
|
L
|
Y
|
S
|
I
|
77 |
V
|
C
|
V
|
V
|
G
|
L
|
F
|
G
|
N
|
F
|
87 |
L
|
V
|
M
|
Y
|
V
|
I
|
V
|
R
|
Y
|
T
|
97 |
ICL1 | TM2 | ||||||||
K
|
M
|
K
|
T
|
A
|
T
|
N
|
I
|
Y
|
I
|
107 |
F
|
N
|
L
|
A
|
L
|
A
|
D
|
A
|
L
|
A
|
117 |
T
|
S
|
T
|
L
|
P
|
F
|
Q
|
S
|
V
|
N
|
127 |
ECL1 | |||||||||
Y
|
L
|
M
|
G
|
T
|
W
|
P
|
F
|
G
|
N
|
137 |
TM3 | |||||||||
I
|
L
|
C
|
K
|
I
|
V
|
I
|
S
|
I
|
D
|
147 |
Y
|
Y
|
N
|
M
|
F
|
T
|
S
|
I
|
F
|
T
|
157 |
L
|
C
|
T
|
M
|
S
|
V
|
D
|
R
|
Y
|
I
|
167 |
ICL2 | |||||||||
A
|
V
|
C
|
H
|
P
|
V
|
K
|
A
|
L
|
D
|
177 |
TM4 | |||||||||
F
|
R
|
T
|
P
|
R
|
N
|
A
|
K
|
I
|
V
|
187 |
N
|
V
|
C
|
N
|
W
|
I
|
L
|
S
|
S
|
A
|
197 |
I
|
G
|
L
|
P
|
V
|
M
|
F
|
M
|
A
|
T
|
207 |
ECL2 | |||||||||
T
|
K
|
Y
|
R
|
Q
|
G
|
S
|
I
|
D
|
C
|
217 |
TM5 | |||||||||
T
|
L
|
T
|
F
|
S
|
H
|
P
|
T
|
W
|
Y
|
227 |
W
|
E
|
N
|
L
|
L
|
K
|
I
|
C
|
V
|
F
|
237 |
I
|
F
|
A
|
F
|
I
|
M
|
P
|
V
|
L
|
I
|
247 |
I
|
T
|
V
|
C
|
Y
|
G
|
L
|
M
|
I
|
L
|
257 |
ICL3 | |||||||||
R
|
L
|
K
|
S
|
V
|
R
|
M
|
L
|
S
|
G
|
267 |
TM6 | |||||||||
S
|
K
|
E
|
K
|
D
|
R
|
N
|
L
|
R
|
R
|
277 |
I
|
T
|
R
|
M
|
V
|
L
|
V
|
V
|
V
|
A
|
287 |
V
|
F
|
I
|
V
|
C
|
W
|
T
|
P
|
I
|
H
|
297 |
I
|
Y
|
V
|
I
|
I
|
K
|
A
|
L
|
I
|
T
|
307 |
ECL3 | TM7 | ||||||||
I
|
P
|
E
|
T
|
T
|
F
|
Q
|
T
|
V
|
S
|
317 |
W
|
H
|
F
|
C
|
I
|
A
|
L
|
G
|
Y
|
T
|
327 |
N
|
S
|
C
|
L
|
N
|
P
|
V
|
L
|
Y
|
A
|
337 |
H8 | |||||||||
F
|
L
|
D
|
E
|
N
|
F
|
K
|
R
|
C
|
F
|
347 |
R
|
E
|
F
|
C
|
I
|
P
|
T
|
S
|
S
|
T
|
357 |
|
|||||
C-term | |||||
I
|
|
||||
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
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Remarks:
PURIFICATION
Purification type | Description |
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Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|