PDB
11TK
Resolution
3.5 Å
Released
April 1, 2026
Receptor
CCR4
Class
A
Species
Homo sapiens
Ligand
AZD2098
Function
Antagonist
Reference
—

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
AZD2098 L64 1.57x57 TM1 hydrophobic
AZD2098 L78 2.43x43 TM2 hydrophobic
AZD2098 A355 6.33x33 TM6 hydrophobic
AZD2098 M358 6.36x36 TM6 hydrophobic
AZD2098 Y419 7.53x53 TM7 hydrophobic
AZD2098 E424 ICL4 Van der Waals
AZD2098 E424 ICL4 polar (hydrogen bond with backbone)
AZD2098 K425 8.49x49 H8 polar (hydrogen bond with backbone)
AZD2098 K425 8.49x49 H8 Van der Waals
AZD2098 F426 8.50x50 H8 Van der Waals
AZD2098 F426 8.50x50 H8 aromatic (face-to-face)

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 K R L R ICL1ECL1 Q W V F ECL1ICL2 A V F S L R A R ICL2ECL2 T C Y T E R N H T Y C K T K Y S L ECL2ICL3 K N ICL3ECL3 L Q ECL3N-term M N P T D I A D T T L D E S I Y S N Y Y L Y E S I P K P C T N-termC-term T C R G L F V L C Q Y C G L L Q I Y S A D T P S S S Y T Q S T M D H D L H D A L C-term K E G I K A F G E L F L P P L Y S L V F V F G L L G N S V V V L V L F K Y S M T D V Y L L N L A I S D L L F V F S L P F W G Y Y A A D G L G L C K M I S W M Y L V G F Y S G I F F V M L M S I D R Y L A I V H T L T Y G V I T S L A T W S V A V F A S L P G F L F S N S T T W K V L S S L E I N I L G L V I P L G I M L F C Y S M I I R T L Q H C E K K N K A V K M I F A V V V L F L G F W T P Y N I V L F L E T L V E L E V D C T F E R Y L D Y A I Q A T E T L A F V H C C L N P I I Y F F L G E K I L Q F R K Y L F K
Helix box plot — Download: PNG | SVG S N G L L G F V F V L S Y L P P L F L E 1 L N L A I S D L L F V F S L P F W G Y Y 2 L M V F F I G S Y F G V L Y M W S I M K 3 G V I T S L A T W S V A V F A S L P G 4 Y C F L M I G L P I V L G L I N I E L S S 5 F A V V V L F L G F W T P Y N I V L F L 6 I P N L C C H V F A L T E T A Q I A Y 7

GPCRdb(A)
GPCRdb(A)
CCR4
TM1
1x57 1.57x57 L64
TM2
2x43 2.43x43 L78
TM6
6x33 6.33x33 A240
6x36 6.36x36 M243
TM7
7x53 7.53x53 Y304
H8
8x49 8.49x49 K310
8x50 8.50x50 F311