Structure information

κ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4DJH

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

A

PUBLICATION DATE

March 21, 2012

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JDTic W124 23.50x50 ECL1 hydrophobic
JDTic V134 3.28x28 TM3 hydrophobic
JDTic D138 3.32x32 TM3 polar (charge-charge)
JDTic D138 3.32x32 TM3 polar (charge-charge)
JDTic D138 3.32x32 TM3 polar (charge-assisted hydrogen bond)
JDTic M142 3.36x36 TM3 hydrophobic
JDTic V230 5.42x43 TM5 hydrophobic
JDTic I290 6.51x51 TM6 hydrophobic
JDTic I294 6.55x55 TM6 hydrophobic
JDTic I316 7.39x38 TM7 hydrophobic
JDTic Y320 7.43x42 TM7 hydrophobic

Ligands

JDTic

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Residue Diagrams

S N G V L G V V F V V S Y V A T I I V P 1 F N L A L A D A L V T T T M P F Q S T V 2 M T L T F I S T F M N Y Y D I S I V I K 3 A K I I N I C I W L L S S S V G I S A I 4 Y C V I I I L V P I V F A F I F V C I K M 5 L V V V A V F V V C W T P I H I F I L V 6 I P N L S S N T Y G L A I C F Y Y S S 7
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ICL1 T K M K ICL1ECL1 S W P F ECL1ICL2 P V K A L D F R ICL2ECL2 G T K V R E D V D V I E C S L Q F P D D ECL2ICL3 R L L S G ICL3ECL3 S T S H ECL3N-term M D S P I Q I F R G E P G P T C A P S A C L P P N S S A W F P G W A E P D S N G S A G S E D A Q L E P A H I S P N-termC-term P L K M R M E R Q S T S R V R N T V Q D P A Y L R D I D G M N K P V C-term A I P V I I T A V Y S V V F V V G L V G N S L V M F V I I R Y T A T N I Y I F N L A L A D A L V T T T M P F Q S T V Y L M N G D V L C K I V I S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P L K A K I I N I C I W L L S S S V G I S A I V L G D Y S W W D L F M K I C V F I F A F V I P V L I I I V C Y T L M I L R L K S V S R E K D R N L R R I T R L V L V V V A V F V V C W T P I H I F I L V E A L G S T A A L S S Y Y F C I A L G Y T N S S L N P I L Y A F L D E N F R D F K R C F C F
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Residue Table


GPCRdb(A)
GPCRdb(A)
κ receptor
ECL1
23x50 23.50x50 W124
TM3
3x28 3.28x28 V134
3x32 3.32x32 D138
3x36 3.36x36 M142
TM5
5x43 5.42x43 V230
TM6
6x51 6.51x51 I290
6x55 6.55x55 I294
TM7
7x38 7.39x38 I316
7x42 7.43x42 Y320