GPCRdb

Ligand	Amino Acid	Generic Number	Segment	Interaction Type


NTS8–13	L55		N-term	polar (hydrogen bond with backbone)
NTS8–13	L55		N-term	hydrophobic
NTS8–13	D56		N-term	Van der Waals
NTS8–13	V57		N-term	Van der Waals
NTS8–13	F128	2.65x64	TM2	hydrophobic
NTS8–13	H132		ECL1	Van der Waals
NTS8–13	H133		ECL1	Van der Waals
NTS8–13	Y146	3.29x29	TM3	polar (hydrogen bond)
NTS8–13	R149	3.32x32	TM3	polar (charge-charge)
NTS8–13	M208	4.64x65	TM4	hydrophobic
NTS8–13	R213		ECL2	Van der Waals
NTS8–13	V224		ECL2	hydrophobic
NTS8–13	C225	45.50x50	ECL2	Van der Waals
NTS8–13	T226	45.51x51	ECL2	polar (hydrogen bond)
NTS8–13	P227	45.52x52	ECL2	Van der Waals
NTS8–13	R327	6.54x54	TM6	polar (hydrogen bond)
NTS8–13	R327	6.54x54	TM6	polar (charge-charge)
NTS8–13	R328	6.55x55	TM6	hydrophobic
NTS8–13	R328	6.55x55	TM6	polar (charge-charge)
NTS8–13	F331	6.58x58	TM6	aromatic (pi-cation)
NTS8–13	F331	6.58x58	TM6	hydrophobic
NTS8–13	F331	6.58x58	TM6	polar (hydrogen bond with backbone)
NTS8–13	S335		ECL3	Van der Waals
NTS8–13	D336		ECL3	polar (charge-charge)
NTS8–13	E337		ECL3	polar (charge-charge)
NTS8–13	W339		ECL3	hydrophobic
NTS8–13	T341	7.25x24	TM7	Van der Waals
NTS8–13	F344	7.28x27	TM7	aromatic (pi-cation)
NTS8–13	F344	7.28x27	TM7	hydrophobic
NTS8–13	Y347	7.31x30	TM7	hydrophobic
NTS8–13	Y347	7.31x30	TM7	polar (hydrogen bond)
NTS8–13	H348	7.32x31	TM7	Van der Waals
NTS8–13	Y351	7.35x34	TM7	hydrophobic