Structure information

δ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4N6H

SPECIES

Homo sapiens

RESOLUTION

1.800

PREFERRED CHAIN

A

PUBLICATION DATE

Dec. 25, 2013

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Naltrindole D128 3.32x32 TM3 polar (charge-assisted hydrogen bond)
Naltrindole D128 3.32x32 TM3 polar (charge-charge)
Naltrindole Y129 3.33x33 TM3 polar (hydrogen bond)
Naltrindole M132 3.36x36 TM3 hydrophobic
Naltrindole W274 6.48x48 TM6 hydrophobic
Naltrindole I277 6.51x51 TM6 hydrophobic
Naltrindole H278 6.52x52 TM6 aromatic (face-to-edge)
Naltrindole V281 6.55x55 TM6 hydrophobic
Naltrindole W284 6.58x58 TM6 aromatic (face-to-edge)

Ligands

Naltrindole

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Residue Diagrams

V N G L L G V A C V A S Y L A T I A I A 1 F N L A L A D A L A T S T L P F Q S A K 2 M T L T F I S T F M N Y Y D I S L V A K 3 A K L I N I C I W V L A S G V G V P I M 4 Y C V T I I L I P V V F A F L F V C I K T 5 L V V V G A F V V C W A P I H I F V I V 6 V P N L S S N A Y G L A I C L H L A A 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 V T R P R D G A V V C M L Q F P S ECL2ICL3 R L L S G ICL3ECL3 D I D R R ECL3N-term M E P A P S A G A E L Q P P L F A N A S D A Y P S A C P S A G A N A S G P P N-termC-term P C G R P D P S S F S R A R E A T A R E R V T A C T P S D G P G G G A A A C-term G A R S A S S L A L A I A I T A L Y S A V C A V G L L G N V L V M F G I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S A K Y L M E G E L L C K A V L S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P A K A K L I N I C I W V L A S G V G V P I M V M A P S W Y W D T V T K I C V F L F A F V V P I L I I T V C Y G L M L L R L R S V S K E K D R S L R R I T R M V L V V V G A F V V C W A P I H I F V I V W T L V D P L V V A A L H L C I A L G Y A N S S L N P V L Y A F L D E N F R Q F K R C L C R K
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Residue Table


GPCRdb(A)
GPCRdb(A)
δ receptor
TM3
3x32 3.32x32 D128
3x33 3.33x33 Y129
3x36 3.36x36 M132
TM6
6x48 6.48x48 W274
6x51 6.51x51 I277
6x52 6.52x52 H278
6x55 6.55x55 V281
6x58 6.58x58 W284