Structure information

δ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4RWD

SPECIES

Homo sapiens

RESOLUTION

2.700

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Jan. 14, 2015

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
DIPP-NH2 L125 3.29x29 TM3 hydrophobic
DIPP-NH2 D128 3.32x32 TM3 polar (charge-charge)
DIPP-NH2 Y129 3.33x33 TM3 aromatic (face-to-edge)
DIPP-NH2 M132 3.36x36 TM3 hydrophobic
DIPP-NH2 M199 45.51x51 ECL2 hydrophobic
DIPP-NH2 L200 45.52x52 ECL2 polar (hydrogen bond with backbone)
DIPP-NH2 L200 45.52x52 ECL2 polar (hydrogen bond with backbone)
DIPP-NH2 K214 5.39x40 TM5 polar (hydrogen bond with backbone)
DIPP-NH2 V217 5.42x43 TM5 hydrophobic
DIPP-NH2 I277 6.51x51 TM6 hydrophobic
DIPP-NH2 V281 6.55x55 TM6 hydrophobic
DIPP-NH2 I304 7.39x38 TM7 hydrophobic
DIPP-NH2 Y308 7.43x42 TM7 polar (charge-assisted hydrogen bond)

Ligands

DIPP-NH2

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Residue Diagrams

V N G L L G V A C V A S Y L A T I A I A 1 F N L A L A D A L A T S T L P F Q S A K 2 M T L T F I S T F M N Y Y D I S L V A K 3 A K L I N I C I W V L A S G V G V P I M 4 Y C V T I I L I P V V F A F L F V C I K T 5 L V V V G A F V V C W A P I H I F V I V 6 V P N L S S N A Y G L A I C L H L A A 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 V T R P R D G A V V C M L Q F P S ECL2ICL3 R L L S G ICL3ECL3 D I D R R ECL3N-term M E P A P S A G A E L Q P P L F A N A S D A Y P S A C P S A G A N A S G P P N-termC-term P C G R P D P S S F S R A R E A T A R E R V T A C T P S D G P G G G A A A C-term G A R S A S S L A L A I A I T A L Y S A V C A V G L L G N V L V M F G I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S A K Y L M E G E L L C K A V L S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P A K A K L I N I C I W V L A S G V G V P I M V M A P S W Y W D T V T K I C V F L F A F V V P I L I I T V C Y G L M L L R L R S V S K E K D R S L R R I T R M V L V V V G A F V V C W A P I H I F V I V W T L V D P L V V A A L H L C I A L G Y A N S S L N P V L Y A F L D E N F R Q F K R C L C R K
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Residue Table


GPCRdb(A)
GPCRdb(A)
δ receptor
TM3
3x29 3.29x29 L125
3x32 3.32x32 D128
3x33 3.33x33 Y129
3x36 3.36x36 M132
ECL2
45x51 45.51x51 M199
45x52 45.52x52 L200
TM5
5x40 5.39x40 K214
5x43 5.42x43 V217
TM6
6x51 6.51x51 I277
6x55 6.55x55 V281
TM7
7x38 7.39x38 I304
7x42 7.43x42 Y308