Structure information

M3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4U16

SPECIES

Rattus norvegicus

RESOLUTION

3.700

PREFERRED CHAIN

B

PUBLICATION DATE

Nov. 26, 2014

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
N-methyl scopolamine D147 3.32x32 TM3 polar (hydrogen bond with backbone)
N-methyl scopolamine Y148 3.33x33 TM3 hydrophobic
N-methyl scopolamine S151 3.36x36 TM3 polar (hydrogen bond)
N-methyl scopolamine W199 4.57x57 TM4 hydrophobic
N-methyl scopolamine A238 5.46x461 TM5 hydrophobic
N-methyl scopolamine W503 6.48x48 TM6 hydrophobic
N-methyl scopolamine Y506 6.51x51 TM6 hydrophobic
N-methyl scopolamine N507 6.52x52 TM6 polar (hydrogen bond)
N-methyl scopolamine N507 6.52x52 TM6 polar (hydrogen bond)
N-methyl scopolamine N507 6.52x52 TM6 polar (hydrogen bond)
N-methyl scopolamine Y529 7.39x38 TM7 hydrophobic
N-methyl scopolamine C532 7.42x41 TM7 hydrophobic

Ligands

N-methyl scopolamine

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N G I I T V L A L F G T L F A I F V V 1 L S L A C A D L I I G I V S M N L F T T Y 2 V L L N M V S A N S A V Y D I S L W L D 3 A G V M I G L A W V I S F V L W A P A I 4 Y L I T M I T V P M Y F A A I A T G F T I 5 S A I L L A F I I T W T P Y N I M V L V 6 V P N V T S N I Y C L W Y G L N W Y T 7
Download: PNG | SVG
ICL1 K Q L K ICL1ECL1 N R W A L ECL1ICL2 P L T Y R A K R ICL2ECL2 K R T V P P G E C F I Q F L S ECL2ICL3 Q A S G T E A E A E N F V H P T G S S R S C S S Y E L Q Q Q G V K R S S R R K Y G R C H F W F T T K S W K P S A E Q M D Q D H S S S D S W N N N D A A A S L E N S A S S D E E D I G S E T R A I Y S I V L K L P G H S S I L N S T K L P S S D N L Q V S N E D L G T V D V E R N A H K L Q A Q K S M G D G D N C Q K D F T K L P I Q L E S A V D T G K T S D T N S S A D K T T A T L P L S F K E A T L A K R F A L K T R S Q I T K R K ICL3ECL3 D S C I ECL3N-term M T L H S N S T T S P L F P N I S S S W V H S P S E A G L P L G T V T Q L G S Y N I S Q E T G N F S S N D T S S D P L G G H N-termC-term Q C D K R K R R K Q Q Y Q Q R Q S V I F H K R V P E Q A L C-term T I W Q V V F I A F L T G F L A L V T I I G N I L V I V A F K V N T V N N Y F L L S L A C A D L I I G V I S M N L F T T Y I I M G N L A C D L W L S I D Y V A S N A S V M N L L V I S F D R Y F S I T R T T K R A G V M I G L A W V I S F V L W A P A I L F W Q Y F V G E P T I T F G T A I A A F Y M P V T I M T I L Y W R I Y K E T E K R T K E L A G L R M S L I K E K K A A Q T L S A I L L A F I I T W T P Y N I M V L V N T F C P K T Y W N L G Y W L C Y I N S T V N P V C Y A L C N K T F K T F R T T L L L C
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
M3 receptor
TM3
3x32 3.32x32 D147
3x33 3.33x33 Y148
3x36 3.36x36 S151
TM4
4x57 4.57x57 W199
TM5
5x461 5.46x461 A238
TM6
6x48 6.48x48 W503
6x51 6.51x51 Y506
6x52 6.52x52 N507
TM7
7x38 7.39x38 Y529
7x41 7.42x41 C532