Structure information

M4 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5DSG

SPECIES

Homo sapiens

RESOLUTION

2.600

PREFERRED CHAIN

B

PUBLICATION DATE

March 16, 2016

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
tiotropium Y113 3.33x33 TM3 hydrophobic
tiotropium S116 3.36x36 TM3 polar (hydrogen bond)
tiotropium W164 4.57x57 TM4 hydrophobic
tiotropium W413 6.48x48 TM6 aromatic (edge-to-face)
tiotropium Y416 6.51x51 TM6 hydrophobic
tiotropium N417 6.52x52 TM6 polar (hydrogen bond)
tiotropium N417 6.52x52 TM6 polar (hydrogen bond)
tiotropium N417 6.52x52 TM6 polar (hydrogen bond)
tiotropium Y439 7.39x38 TM7 hydrophobic
tiotropium C442 7.42x41 TM7 hydrophobic

Ligands

tiotropium

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N G V V T V L S L S G T V T A I F V M 1 F S L A C A D L I I G F A S M N L Y T V Y 2 I L L N M V S A N S V V Y D L A L W L D 3 A G L M I A A A W V L S F V L W A P A I 4 Y L V T M I V V P L Y F A A I A T G F T V 5 F A I L L A F I L T W T P Y N V M V L V 6 A P N I T S N V Y C L W Y G I S W V T 7
Download: PNG | SVG
ICL1 R Q L Q ICL1ECL1 Y W P L ECL1ICL2 P L T Y P A R R ICL2ECL2 K R T V P D N Q C F I Q F L S ECL2ICL3 G P K E K K A K T L A F L K S P L M K Q S V K K P P P G E A A R E E L R N G K L E E A P P P A L P P P P R P V A D K D T S N E S S S G S A T Q N T K E R P A T E L S T T E A T T P A M P A P P L Q P R A L N P A S R W S K I Q I V T K Q T G N E C V T A I E I V P A T P A G M R P A A N V A R K F A S I A R N Q V R K K ICL3ECL3 Q S C I ECL3N-term M A N F T P V N G S S G N Q S V R L V T S S S H N N-termC-term Y R N I G T A R C-term R Y E T V E M V F I A T V T G S L S L V T V V G N I L V M L S I K V N T V N N Y F L F S L A C A D L I I G A F S M N L Y T V Y I I K G G A V V C D L W L A L D Y V V S N A S V M N L L I I S F D R Y F C V T K T T K M A G L M I A A A W V L S F V L W A P A I L F W Q F V V G N P A V T F G T A I A A F Y L P V V I M T V L Y I H I S L A S R S R V H K H R P E R Q M A A R E R K V T R T I F A I L L A F I L T W T P Y N V M V L V N T F C P D T V W S I G Y W L C Y V N S T I N P A C Y A L C N A T F R H Q F K K T L L L C
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
M4 receptor
TM3
3x33 3.33x33 Y113
3x36 3.36x36 S116
TM4
4x57 4.57x57 W164
TM6
6x48 6.48x48 W413
6x51 6.51x51 Y416
6x52 6.52x52 N417
TM7
7x38 7.39x38 Y439
7x41 7.42x41 C442