Structure information

A1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5N2S

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

A

PUBLICATION DATE

July 26, 2017

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
PSB36 F1276 45.52x52 ECL2 aromatic (face-to-face)
PSB36 M1285 5.38x40 TM5 hydrophobic
PSB36 W1352 6.48x48 TM6 hydrophobic
PSB36 L1355 6.51x51 TM6 hydrophobic
PSB36 L1358 6.54x54 TM6 hydrophobic
PSB36 N1359 6.55x55 TM6 polar (hydrogen bond)
PSB36 N1359 6.55x55 TM6 polar (hydrogen bond)

Ligands

PSB36

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Residue Diagrams

V N G P V S V L A I L V E I G I Y A A Q 1 V S L A V A D V A V G L A V I P L A I L I 2 A L L A L I S S Q T L I L V P C A V M L 3 A A V A I A G C W I L S F V V G L T P M 4 Y I L V M L L L P P L V W V F F N F Y V M Y 5 A L I L F L F A L S W L P L H I L N C I 6 I P N M A S N G H T L F I A I Y T L I 7
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ICL1 Q A L R ICL1ECL1 P Q T ECL1ICL2 P L R Y K M V V ICL2ECL2 W N N L S A V E R A W A A N G S M G E P V I K C E F E K V I ECL2ICL3 S A S S G ICL3ECL3 P S C H K ECL3N-term M P P S I N-termC-term I D E D L P E E R P D D C-term S A F Q A A Y I G I E V L I A L V S V P G N V L V I W A V K V N D A T F C F I V S L A V A D V A V G A L V I P L A I L I N I G Y F H T C L M V A C P V L I L T Q S S I L A L L A I A V D R Y L R V K I T P R R A A V A I A G C W I L S F V V G L T P M F G S M E Y M V Y F N F F V W V L P P L L L M V L I Y L E V F Y L I R K Q L N K K V D P Q K Y Y G K E L K I A K S L A L I L F L F A L S W L P L H I L N C I T L F C P S I L T Y I A I F L T H G N S A M N P I V Y A F R I Q K F L K H F R P P F R V T I W N D C Q P A
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Residue Table


GPCRdb(A)
GPCRdb(A)
A1 receptor
ECL2
45x52 45.52x52 F171
TM5
5x40 5.38x40 M180
TM6
6x48 6.48x48 W247
6x51 6.51x51 L250
6x54 6.54x54 L253
6x55 6.55x55 N254