Structure information

PAR2

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5NDD

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

A

PUBLICATION DATE

May 3, 2017

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
AZ8838 Y82 1.39x39 TM1 polar (hydrogen bond)
AZ8838 H135 2.64x64 TM2 aromatic (edge-to-face)
AZ8838 H135 2.64x64 TM2 polar (hydrogen bond)
AZ8838 F155 3.32x32 TM3 aromatic (face-to-edge)
AZ8838 C226 45.50x50 ECL2 hydrophobic
AZ8838 H227 45.51x51 ECL2 aromatic (face-to-face)
AZ8838 D228 45.52x52 ECL2 polar (charge-assisted hydrogen bond)
AZ8838 L330 7.39x38 TM7 hydrophobic

Ligands

AZ8838

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Residue Diagrams

G N S P L G V V F V I T Y V I P L F V T 1 A N L A L A D L L S V I W F P L K I A Y 2 C T M F L I S C Y M N G Y F F G I L V N 3 A I G I S L A I W L L I L L V T I P L 4 Y A S A T L F A P F L F V G I A L S L F Y 5 I V T V L A M Y I L C F T P S N L L L V V 6 F P D I C S N L T S L C L A V I Y L A 7
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ICL1 T K K K ICL1ECL1 G N N W I Y ECL1ICL2 P M G H S R K ICL2ECL2 V K Q T I F I P A L N I T T C H D V L P E Q L ECL2ICL3 A M D ICL3ECL3 G Q S H ECL3N-term M R S P S A A W L L G A A I L L A A S L S C S G T I Q G T N R S S K G R S L I G K V D G T S H V T G K G V T V E T V F S V D E F S A S V L T N-termC-term S V R T V K Q M Q V S L T S K K H S R K S S S Y S S S S T T V K T S Y C-term G K L T T V F L P I V Y T I V F V V G L P S N G M A L W V F L F R H P A V I Y M A N L A L A D L L S V I W F P L K I A Y H I H G E A L C N V L I G F F Y G N M Y C S I L F M T C L S V Q R Y W V I V N K A N I A I G I S L A I W L L I L L V T I P L Y V L V G D M F N Y F L S L A I G V F L F P A F L T A S A Y V L M I R M L R S S E N S E K K R K R A I K L I V T V L A M Y L I C F T P S N L L L V V H Y F L I K S Q V Y A L Y I V A L C L S T L N S C I D P F V Y Y F V S H D A K N R F R D H A L L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
PAR2
TM1
1x39 1.39x39 Y82
TM2
2x64 2.64x64 H135
TM3
3x32 3.32x32 F155
ECL2
45x50 45.50x50 C226
45x51 45.51x51 H227
45x52 45.52x52 D228
TM7
7x38 7.39x38 L330