Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5T04

SPECIES

Rattus norvegicus

RESOLUTION

3.300

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Dec. 21, 2016

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
neurotensin D54 N-term polar (hydrogen bond with backbone)
neurotensin L55 N-term polar (hydrogen bond with backbone)
neurotensin F128 2.65x64 TM2 hydrophobic
neurotensin Y146 3.29x29 TM3 polar (charge-assisted hydrogen bond)
neurotensin Y146 3.29x29 TM3 polar (hydrogen bond)
neurotensin T226 45.51x51 ECL2 polar (hydrogen bond)
neurotensin T231 5.32x33 TM5 polar (charge-assisted hydrogen bond)
neurotensin R327 6.54x54 TM6 polar (charge-charge)
neurotensin F331 6.58x58 TM6 hydrophobic
neurotensin D336 ECL3 polar (charge-assisted hydrogen bond)
neurotensin W339 ECL3 hydrophobic
neurotensin F344 7.28x27 TM7 hydrophobic
neurotensin Y347 7.31x30 TM7 polar (hydrogen bond)

Ligands

neurotensin

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Residue Diagrams

S N G V T G V V F L A L Y I A T V L V K 1 G S L A L S D L L I L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A I P M 4 N L I S I V L M P F L F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I A S S V Y F L A N T L M Y F Y 7
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ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G L Q N R S G D G T H P G G L V C T P I V D ECL2ICL3 R V C T V G T H N G L E H S T F N M T I E ICL3ECL3 S D E Q W ECL3N-term M H L N S S V P Q G T P G E P D A Q P F S G P Q S E M E A T F L A L S L S N G S G N T S E S D T A G P N S D L D V N T D N-termC-term P G W R H R R K K R P T F S R K P N S M S S N H A F S T S A T R E T L Y C-term I Y S K V L V T A I Y L A L F V V G T V G N S V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L I L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A I P M L F T M T A T V K V V I Q V N T F M S F L F P M L V I S I L N T V I A N K L T V M V H Q A A E Q G P G R V Q A L R H G V L V L R A V V I A F V V C W L P Y H V R R L M F C Y I T T F L F D F Y H Y F Y M L T N A L F Y V S S A I N P I L Y N L V S A N F L S L C F R Q V T L A C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM2
2x64 2.65x64 F128
TM3
3x29 3.29x29 Y146
ECL2
45x51 45.51x51 T226
TM5
5x33 5.32x33 T231
TM6
6x54 6.54x54 R327
6x58 6.58x58 F331
TM7
7x27 7.28x27 F344
7x30 7.31x30 Y347