Structure information

CCR2

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5T1A

SPECIES

Homo sapiens

RESOLUTION

2.810

PREFERRED CHAIN

A

PUBLICATION DATE

Dec. 14, 2016

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
BMS-681 V37 1.27x27 TM1 hydrophobic
BMS-681 L45 1.35x35 TM1 hydrophobic
BMS-681 Y49 1.39x39 TM1 polar (hydrogen bond)
GTPL9431 L81 2.43x43 TM2 hydrophobic
BMS-681 W98 2.60x60 TM2 hydrophobic
BMS-681 Y120 3.32x32 TM3 hydrophobic
GTPL9431 A241 6.33x33 TM6 hydrophobic
BMS-681 Q288 7.36x35 TM7 polar (hydrogen bond with backbone)
BMS-681 T292 7.40x39 TM7 polar (hydrogen bond)
BMS-681 M295 7.43x42 TM7 hydrophobic
GTPL9431 Y305 7.53x53 TM7 aromatic (face-to-edge)
GTPL9431 E310 8.48x48 H8 polar (hydrogen bond with backbone)
GTPL9431 K311 8.49x49 H8 polar (hydrogen bond with backbone)
GTPL9431 F312 8.50x50 H8 polar (hydrogen bond with backbone)

Ligands

BMS-681

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


GTPL9431

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

M N G V F G F I F V L S Y L P P L L Q A 1 L N L A I S D L L F L I T L P L W A H S 2 L I I F F I G G F Y G I H Y L G T F L K 3 G V V T S V I T W L V A V F A S V P G 4 Y C I V M I L L P L V L G L I N R M I T H 5 F T I M I V Y F L F W T P Y N I V I L L 6 I P N I C C H T M G L T E T V Q T A Q 7
Download: PNG | SVG
ICL1 K K L K ICL1ECL1 E W V F ECL1ICL2 A V F A L K A R ICL2ECL2 K C Q K E D S V Y V C G P Y F ECL2ICL3 R N E ICL3ECL3 L S N C ECL3N-term M L S T S R S R F I R N T N E S G E E V T T F F D Y D Y G A P C H K F D N-termC-term G C R I A P L Q K P V C G G P G V R P G K N V K V T T Q G L L D G R G K G K S I G R A P E A S L Q D K E G A C-term V K Q I G A Q L L P P L Y S L V F I F G F V G N M L V V L I L I N C C L T D I Y L L N L A I S D L L F L I T L P L W A H S A A N G N A M C K L F T G L Y H I G Y F G G I F F I I L L T I D R Y L A I V H T V T F G V V T S V I T W L V A V F A S V P G I I F T P R G W N N F H T I M R N I L G L V L P L L I M V I C Y S G I L K T L L R C K K R H R A V R V I F T I M I V Y F L F W T P Y N I V I L L N T F Q E F F G E S T S Q L D Q A T Q V T E T L G M T H C C I N P I I Y A F V G E K F H I F R S L A L
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
CCR2
TM1
1x27 1.27x27 V37
1x35 1.35x35 L45
1x39 1.39x39 Y49
TM2
2x43 2.43x43 L81
2x60 2.60x60 W98
TM3
3x32 3.32x32 Y120
TM6
6x33 6.33x33 A241
TM7
7x35 7.36x35 Q288
7x39 7.40x39 T292
7x42 7.43x42 M295
7x53 7.53x53 Y305
H8
8x48 8.48x48 E310
8x49 8.49x49 K311
8x50 8.50x50 F312