Structure information

US28

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

5WB2

SPECIES

Human cytomegalovirus

RESOLUTION

3.500

PREFERRED CHAIN

A

PUBLICATION DATE

June 13, 2018

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CX3CL1 D17 N-term polar (charge-assisted hydrogen bond)
CX3CL1 D17 N-term polar (charge-assisted hydrogen bond)
CX3CL1 D17 N-term polar (charge-assisted hydrogen bond)
CX3CL1 P22 N-term hydrophobic
CX3CL1 C23 N-term polar (hydrogen bond with backbone)
CX3CL1 C23 N-term polar (hydrogen bond with backbone)
CX3CL1 C23 N-term polar (hydrogen bond with backbone)
CX3CL1 F25 1.24x24 TM1 polar (hydrogen bond with backbone)
CX3CL1 L29 1.28x28 TM1 hydrophobic
CX3CL1 T36 1.35x35 TM1 polar (hydrogen bond)
CX3CL1 L93 2.64x64 TM2 hydrophobic
CX3CL1 V166 ECL2 hydrophobic
CX3CL1 D170 ECL2 polar (hydrogen bond with backbone)
CX3CL1 D170 ECL2 polar (charge-assisted hydrogen bond)
CX3CL1 M174 45.51x51 ECL2 polar (hydrogen bond)
CX3CL1 T175 45.52x52 ECL2 polar (hydrogen bond)
CX3CL1 T175 45.52x52 ECL2 polar (hydrogen bond)
CX3CL1 T175 45.52x52 ECL2 polar (hydrogen bond)
CX3CL1 T175 45.52x52 ECL2 polar (hydrogen bond with backbone)
CX3CL1 D178 ECL2 polar (charge-assisted hydrogen bond)
CX3CL1 N189 5.39x40 TM5 polar (hydrogen bond)
CX3CL1 L192 5.42x43 TM5 hydrophobic
CX3CL1 Y244 6.51x51 TM6 polar (hydrogen bond)
CX3CL1 Y244 6.51x51 TM6 polar (hydrogen bond)
CX3CL1 L248 6.55x55 TM6 hydrophobic
CX3CL1 K270 7.32x31 TM7 polar (charge-assisted hydrogen bond)
CX3CL1 K270 7.32x31 TM7 polar (charge-assisted hydrogen bond)
CX3CL1 L273 7.35x34 TM7 hydrophobic
CX3CL1 I274 7.36x35 TM7 hydrophobic
CX3CL1 E277 7.39x38 TM7 polar (charge-assisted hydrogen bond)
CX3CL1 E277 7.39x38 TM7 polar (charge-assisted hydrogen bond)

Ligands

CX3CL1

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Residue Diagrams

F N G I S G F L F V V G Y L F L T V P K 1 I N L A A A D L L F V C T L P L W M Q Y 2 E T I F C L S A F M A V Y F C A T L L T 3 A C L F S I F W W I F A V I I A I P H 4 Y C Y S I V S L P I V F A G L M L E V N L 5 I A V V L V F I I F W L P Y H L T L F V 6 L P N L C C H C F A L S E T L I L A R 7
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ICL1 R R I Q ICL1ECL1 H N S L ECL1ICL2 Y M R Y R ICL2ECL2 V V T K K D N Q C M T D Y D Y L E V ECL2ICL3 Q S R ICL3ECL3 W I S S ECL3N-term M T P T T T T A E L T T E F D Y D E D A T P C V N-termC-term Q R L F S R D V S W Y H S M S F S R R G S P S R R E T S S D T L S D E V C R V S Q I I P C-term F T D V L N Q S K P V T L F L Y G V V F L F G S I G N F L V I F T I T W R C S G D V Y F I N L A A A D L L F V C T L P L W M Q Y L L D A S V P C T L L T A C F Y V A M F A S L C F I T E I A L D R Y Y A I V P V K Q A C L F S I F W W I F A V I I A I P H F M S Y P I I L N V E L M L G A F V I P L S V I S Y C Y Y R I S R I V A V S H K G R I V R V L I A V V L V F I I F W L P Y H L T L F V D T L K L L K S C E F E R S L K R A L I L T E S L A F C H C C L N P L L Y V F V G T K L H C F R F R Q E L L A E
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Residue Table


GPCRdb(A)
GPCRdb(A)
US28
TM1
1x24 1.24x24 F25
1x28 1.28x28 L29
1x35 1.35x35 T36
TM2
2x64 2.64x64 L93
ECL2
45x51 45.51x51 M174
45x52 45.52x52 T175
TM5
5x40 5.39x40 N189
5x43 5.42x43 L192
TM6
6x51 6.51x51 Y244
6x55 6.55x55 L248
TM7
7x31 7.32x31 K270
7x34 7.35x34 L273
7x35 7.36x35 I274
7x38 7.39x38 E277