Structure information

CCR2

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6GPX

SPECIES

Homo sapiens

RESOLUTION

2.700

PREFERRED CHAIN

B

PUBLICATION DATE

Jan. 2, 2019

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
MK-0812 L45 1.35x35 TM1 hydrophobic
MK-0812 Y49 1.39x39 TM1 polar (hydrogen bond)
MK-0812 W98 2.60x60 TM2 hydrophobic
MK-0812 Y120 3.32x32 TM3 hydrophobic
MK-0812 Q339 polar (hydrogen bond)
MK-0812 E342 polar (charge-charge)
MK-0812 M346 polar (hydrogen bond)

Ligands

MK-0812

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Residue Diagrams

M N G V F G F I F V L S Y L P P L L Q A 1 L N L A I S D L L F L I T L P L W A H S 2 L I I F F I G G F Y G I H Y L G T F L K 3 G V V T S V I T W L V A V F A S V P G 4 Y C I V M I L L P L V L G L I N R M I T H 5 F T I M I V Y F L F W T P Y N I V I L L 6 I P N I C C H T M G L T E T V Q T A Q 7
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ICL1 K K L K ICL1ECL1 E W V F ECL1ICL2 A V F A L K A R ICL2ECL2 K C Q K E D S V Y V C G P Y F ECL2ICL3 R N E ICL3ECL3 L S N C ECL3N-term M L S T S R S R F I R N T N E S G E E V T T F F D Y D Y G A P C H K F D N-termC-term G C R I A P L Q K P V C G G P G V R P G K N V K V T T Q G L L D G R G K G K S I G R A P E A S L Q D K E G A C-term V K Q I G A Q L L P P L Y S L V F I F G F V G N M L V V L I L I N C C L T D I Y L L N L A I S D L L F L I T L P L W A H S A A N G N A M C K L F T G L Y H I G Y F G G I F F I I L L T I D R Y L A I V H T V T F G V V T S V I T W L V A V F A S V P G I I F T P R G W N N F H T I M R N I L G L V L P L L I M V I C Y S G I L K T L L R C K K R H R A V R V I F T I M I V Y F L F W T P Y N I V I L L N T F Q E F F G E S T S Q L D Q A T Q V T E T L G M T H C C I N P I I Y A F V G E K F H I F R S L A L
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Residue Table


GPCRdb(A)
GPCRdb(A)
CCR2
TM1
1x35 1.35x35 L45
1x39 1.39x39 Y49
TM2
2x60 2.60x60 W98
TM3
3x32 3.32x32 Y120