Structure information

NK1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6J21

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

A

PUBLICATION DATE

March 6, 2019

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Aprepitant P112 3.32x32 TM3 hydrophobic
Aprepitant I113 3.33x33 TM3 hydrophobic
Aprepitant W184 ECL2 polar (hydrogen bond)
Aprepitant E193 5.35x36 TM5 polar (charge-assisted hydrogen bond)
Aprepitant T201 5.43x44 TM5 polar (hydrogen bond)
Aprepitant W261 6.48x48 TM6 hydrophobic
Aprepitant F264 6.51x51 TM6 hydrophobic
Aprepitant F268 6.55x55 TM6 aromatic (face-to-edge)

Ligands

Aprepitant

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

V N G V V S T V V I V T Y A A A W L V I 1 V N L A F A E A S M A A F N T V V N F T 2 A T M S Y I S A F V A A I P F F N H F K 3 T K V V I C V I W V L A L L L A F P Q 4 Y A Y G I V L L P L F Y I L V T V C I H Y 5 I V V V C T F A I C W L P F H I F F L L 6 I P N Y M T S S M A L W M I A L Y V Q 7
Download: PNG | SVG
ICL1 K R M R ICL1ECL1 E W Y Y ECL1ICL2 P L Q P R L ICL2ECL2 T T E T M P S R V V C M I E W P E H ECL2ICL3 S S D ICL3ECL3 P D L Y L K K ECL3N-term M D N V L P V D S D L S P N I S T N T S E P N Q F V Q N-termC-term R C C P F I S A G D Y E G L E M K S T R Y L Q T Q G S V Y K V S R L E T T I S T V V G A H E E E P E D G P K A T P S S L D L T S N C S S R S D S K T M T E S F S F S S N V L S C-term P A W Q I V L W A A A Y T V I V V T S V V G N V V V M W I I L A H T V T N Y F L V N L A F A E A S M A A F N T V V N F T Y A V H N G L F Y C K F H N F F P I A A V F A S I Y S M T A V A F D R Y M A I I H S A T A T K V V I C V I W V L A L L L A F P Q G Y Y S P N K I Y E K V Y H I C V T V L I Y F L P L L V I G Y A Y T V V G I T L W A S E I P G D R Y H E Q V S A K R K V V K M M I V V V C T F A I C W L P F H I F F L L P Y I N F I Q Q V Y L A I M W L A M S S T M Y N P I I Y C C L N D R F K H F R L G A F
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
NK1 receptor
TM3
3x32 3.32x32 P112
3x33 3.33x33 I113
TM5
5x36 5.35x36 E193
5x44 5.43x44 T201
TM6
6x48 6.48x48 W261
6x51 6.51x51 F264
6x55 6.55x55 F268