Structure information

CT receptor

PROTEIN CLASS

Class B1 (Secretin)

PDB CODE

6NIY

SPECIES

Homo sapiens

RESOLUTION

3.340

PREFERRED CHAIN

R

PUBLICATION DATE

Jan. 23, 2019

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Calcitonin salmon L142 1.33x33 TM1 hydrophobic
Calcitonin salmon A145 1.36x36 TM1 hydrophobic
Calcitonin salmon I198 2.64x64 TM2 hydrophobic
Calcitonin salmon L291 45.52x52 ECL2 hydrophobic
Calcitonin salmon V293 ECL2 polar (hydrogen bond with backbone)
Calcitonin salmon E294 ECL2 polar (charge-assisted hydrogen bond)
Calcitonin salmon T295 ECL2 polar (hydrogen bond with backbone)
Calcitonin salmon Y299 5.37x38 TM5 polar (hydrogen bond)
Calcitonin salmon H302 5.40x40 TM5 polar (hydrogen bond)
Calcitonin salmon F359 6.56x56 TM6 polar (hydrogen bond with backbone)
Calcitonin salmon P360 ECL3 polar (hydrogen bond with backbone)
Calcitonin salmon P360 ECL3 polar (hydrogen bond with backbone)
Calcitonin salmon W361 ECL3 polar (hydrogen bond)
Calcitonin salmon Y372 7.38x37 TM7 polar (hydrogen bond)

Ligands

Calcitonin salmon

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Residue Diagrams

V L T F I S L S H G V I A L Y Y L V Y A 1 K N M F L T Y I L N S M I I I I H L V E 2 C L M W F Y N C A M M Y Q H F F H L I K 3 R L R W Y Y L G L W G F P L V P T T I H A 4 L F F F N V V L A A M V P G H I I Y L 5 M I L V P L L G I Q F V V F P W 6 T A V F F G Q F H I L S H M V Y D Y I 7
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ICL1 R S L G ICL1ECL1 V P N G E L V R R D ECL1ICL2 A V F T E K Q ICL2ECL2 N D N C W L S V E T H L ECL2ICL3 E ICL3ECL3 R P S ECL3N-term M R F T F T S R C L A L F L L L N H P T P I L P A F S N Q T Y P T I E P K P F L Y V V G R K K M M D A Q Y K C Y D R M Q Q L P A Y Q G E G P Y C N R T W D G W L C W D D T P A G V L S Y Q F C P D Y F P D F D P S E K V T K Y C D E K G V W F K H P E N N R T W S N Y N-termC-term P S N R S A R A A A A A A E A G D I P I Y I C H Q E P R N E P A N N Q G E E S A E I I P L N I I E Q E S S A C-term T M C N A F T P E K L K N A Y V L Y Y L A I V G H S L S I F T L V I S L G I F V F F C Q R V T L H K N M F L T Y I L N S M I I I I H L V E V P V S C K I L H F F H Q Y M M A C N Y F W M L C E G I Y L H T L I V V R L R W Y Y L L G W G F P L V P T T I H A I T R A V Y F L Y I I H G P V M A A L V V N F F F L L N I V R V L V T K M R E T H A E S H M Y L K A V K A T M I L V P L L G I Q F V V F P W N K M L G K I Y D Y V M H S L I H F Q G F F V A T I Y C F C N N E V K R F K I R W G V Q T T Q W A Q Q W N Q R R
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Residue Table


GPCRdb(A)
GPCRdb(B)
CT receptor
TM1
1x29 1.33x33 L142
1x32 1.36x36 A145
TM2
2x57 2.64x64 I198
ECL2
45x52 45.52x52 L291
TM5
5x42 5.37x38 Y299
5x44 5.40x40 H302
TM6
6x51 6.56x56 F359
TM7
7x33 7.38x37 Y372