Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6OSA

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

R

PUBLICATION DATE

July 10, 2019

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
JMV449 E53 N-term polar (hydrogen bond with backbone)
JMV449 H131 ECL1 polar (hydrogen bond)
JMV449 H131 ECL1 polar (hydrogen bond with backbone)
JMV449 Y145 3.29x29 TM3 polar (charge-assisted hydrogen bond)
JMV449 Y145 3.29x29 TM3 polar (charge-assisted hydrogen bond)
JMV449 V223 ECL2 hydrophobic
JMV449 F326 6.58x58 TM6 hydrophobic
JMV449 D331 ECL3 polar (charge-charge)
JMV449 D331 ECL3 polar (charge-assisted hydrogen bond)
JMV449 W334 ECL3 hydrophobic
JMV449 Y339 7.28x27 TM7 hydrophobic
JMV449 Y342 7.31x30 TM7 polar (hydrogen bond)

Ligands

JMV449

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Residue Diagrams

T N G V T G V V F L A L Y V A T V L V K 1 G S L A L S D L L T L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A V P M 4 N L V S I V V M P F I F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I T S S V Y F L A N T V M Y F Y 7
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ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G E Q N R S A D G Q H A G G L V C T P T I ECL2ICL3 Q V C T V G G E H S T F S M A I E ICL3ECL3 S D E Q W ECL3N-term M R L N S S A P G T P G T P A A D P F Q R A Q A G L E E A L L A P G F G N A S G N A S E R V L A A P S S E L D V N T N-termC-term P V W R R R R K R P A F S R K A D S V S S N H T L S S N A T R E T L Y C-term D I Y S K V L V T A V Y L A L F V V G T V G N T V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L T L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A V P M L F T M H T A T V K V V I Q V N T F M S F I F P M V V I S V L N T I I A N K L T V M V R Q A A E Q G P G R V Q A L R H G V R V L R A V V I A F V V C W L P Y H V R R L M F C Y I T P F L Y D F Y H Y F Y M V T N A L F Y V S S T I N P I L Y N L V S A N F L A L C F R H I T L A C
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Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM3
3x29 3.29x29 Y145
TM6
6x58 6.58x58 F326
TM7
7x27 7.28x27 Y339
7x30 7.31x30 Y342