Structure information
CRF1 receptorPROTEIN CLASS
Class B1 (Secretin)
PDB CODE
6P9X
SPECIES
Homo sapiens
RESOLUTION
2.910
PREFERRED CHAIN
R
REFERENCEPUBLICATION DATE
Feb. 5, 2020
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Ligand Interaction Browser
Download list in excelLigand | Amino Acid | Generic Number | Segment | Interaction Type |
---|---|---|---|---|
Ligand | Amino Acid | Generic Number | Segment | Interaction Type |
Corticoliberin | Y116 | 1.36x36 | TM1 | hydrophobic |
Corticoliberin | V172 | 2.67x67 | TM2 | hydrophobic |
Corticoliberin | Y195 | 3.36x36 | TM3 | polar (hydrogen bond) |
Corticoliberin | F260 | 45.52x52 | ECL2 | polar (hydrogen bond with backbone) |
Corticoliberin | Q273 | 5.40x40 | TM5 | polar (charge-assisted hydrogen bond) |
Corticoliberin | M276 | 5.43x43 | TM5 | hydrophobic |
Corticoliberin | Y327 | 6.53x53 | TM6 | polar (hydrogen bond with backbone) |
Corticoliberin | F331 | ECL3 | polar (hydrogen bond with backbone) | |
Corticoliberin | V332 | ECL3 | hydrophobic | |
Corticoliberin | F344 | 7.38x37 | TM7 | hydrophobic |
Corticoliberin | I345 | 7.39x38 | TM7 | hydrophobic |
Corticoliberin | E352 | 7.46x45 | TM7 | polar (charge-assisted hydrogen bond) |
Ligands
Corticoliberin
Residue Diagrams
Residue Table
GPCRdb(A)
|
GPCRdb(B)
|
CRF1 receptor
|
---|---|---|
TM1 | ||
1x32 | 1.36x36 | Y116 |
TM2 | ||
2x60 | 2.67x67 | V172 |
TM3 | ||
3x32 | 3.36x36 | Y195 |
ECL2 | ||
45x52 | 45.52x52 | F260 |
TM5 | ||
5x44 | 5.40x40 | Q273 |
5x47 | 5.43x43 | M276 |
TM6 | ||
6x48 | 6.53x53 | Y327 |
TM7 | ||
7x33 | 7.38x37 | F344 |
7x34 | 7.39x38 | I345 |
7x41 | 7.46x45 | E352 |