Structure information

M2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6U1N

SPECIES

Homo sapiens

RESOLUTION

4.000

PREFERRED CHAIN

R

PUBLICATION DATE

Feb. 26, 2020

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
2CU C176 45.50x50 ECL2 polar (hydrogen bond with backbone)
2CU Y177 45.51x51 ECL2 hydrophobic
2CU N410 6.58x58 TM6 polar (hydrogen bond)
2CU N410 6.58x58 TM6 polar (hydrogen bond)
2CU N410 6.58x58 TM6 polar (hydrogen bond)
2CU A414 ECL3 hydrophobic
2CU N419 ECL3 polar (hydrogen bond with backbone)
2CU W422 7.35x34 TM7 aromatic (face-to-face)
2CU W422 7.35x34 TM7 polar (hydrogen bond)

Ligands

2CU

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

I N G I I T V L S L S G A V L V I F V V 1 F S L A C A D L I I G F V S M N L Y T L Y 2 I L L N M V S A N S V V Y D L A L W L D 3 A G M M I A A A W V L S F I L W A P A I 4 Y L V T M I I V P L Y F A A I A T G F T V 5 L A I L L A F I I T W A P Y N V M V L I 6 A P N I T S N I Y C L W Y G I T W V T 7
Download: PNG | SVG
ICL1 R H L Q ICL1ECL1 Y W P L ECL1ICL2 P L T Y P V K R ICL2ECL2 V R T V E D G E C Y I Q F F S ECL2ICL3 P V A N Q D P V S P S L V Q G R I V K P N N N N M P S S D D G L E H N K I Q N G K A P R D P V T E N C V Q G E E K E S S N D S T S V S A V A S N M R D D E I T Q D E N T V S T S L G H S K D E N S K Q T C I R I G T K T P K S D S C T P T N T T V E V V G S S G Q N G D E K Q N I V A R K I V K M T K Q P A K K ICL3ECL3 A P C I ECL3N-term M N N S T N S S N N S L A L T S P Y N-termC-term C H Y K N I G A T R C-term K T F E V V F I V L V A G S L S L V T I I G N I L V M V S I K V N T V N N Y F L F S L A C A D L I I G V F S M N L Y T L Y T V I G G P V V C D L W L A L D Y V V S N A S V M N L L I I S F D R Y F C V T K T T K M A G M M I A A A W V L S F I L W A P A I L F W Q F I V G N A A V T F G T A I A A F Y L P V I I M T V L Y W H I S R A S K S R I K K D K K E K P P P S R E K K V T R T I L A I L L A F I I T W A P Y N V M V L I N T F C P N T V W T I G Y W L C Y I N S T I N P A C Y A L C N A T F K H F K K T L L M
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
M2 receptor
ECL2
45x50 45.50x50 C176
45x51 45.51x51 Y177
TM6
6x58 6.58x58 N410
TM7
7x34 7.35x34 W422