Structure information

β2-adrenoceptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7BZ2

SPECIES

Homo sapiens

RESOLUTION

3.820

PREFERRED CHAIN

R

PUBLICATION DATE

Aug. 5, 2020

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Formoterol H93 2.64x63 TM2 aromatic (face-to-edge)
Formoterol W109 3.28x28 TM3 hydrophobic
Formoterol V114 3.33x33 TM3 hydrophobic
Formoterol F193 45.52x52 ECL2 hydrophobic
Formoterol S203 5.42x43 TM5 polar (hydrogen bond)
Formoterol S203 5.42x43 TM5 polar (hydrogen bond)
Formoterol F290 6.52x52 TM6 hydrophobic
Formoterol Y316 7.43x42 TM7 polar (charge-assisted hydrogen bond)
Formoterol Y316 7.43x42 TM7 polar (hydrogen bond)

Ligands

Formoterol

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Residue Diagrams

V N G F V I A L V I L S M V I G M G V V 1 T S L A C A D L V M G A L V V P F G A A H 2 V C L T E I S A T V C L V D I S T W F E 3 A R V I I L M V W I V S G L T S F L P I 4 Y V F V M I V L P V Y F S V I S S A I A Y 5 G I I M G T F T L C W L P F F I V N I V 6 L P N F G S N V Y G I W N L L I Y V E 7
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ICL1 E R L Q ICL1ECL1 M W T F ECL1ICL2 P F K Y Q S L L ICL2ECL2 W Y R A T H Q E A I N C Y A N E T C C D F F T ECL2ICL3 G R F H V Q N L S Q V E Q D G R T G H G L R R S ICL3ECL3 D N L I ECL3N-term M G Q P G N G S A F L L A P N G S H A P D H D V T N-termC-term L R R S S L K A Y G N G Y S S N G N T G E Q S G Y H V E Q E K E N K L L C E D L P G T E D F V G H Q G T V P S D N I D S Q G R N C S T N D S L L C-term Q E R D E V W V V G M G I V M S L I V L A I V F G N V L V I T A I A K F T V T N Y F I T S L A C A D L V M G L A V V P F G A A H I L M K G N F W C E F W T S I D V L C V T A S I E T L C V I A V D R Y F A I T S T K N K A R V I I L M V W I V S G L T S F L P I Q M H N Q A Y A I A S S I V S F Y V P L V I M V F V Y S R V F Q E A K R Q L Q K I D K S E S K F C L K E H K A L K T L G I I M G T F T L C W L P F F I V N I V H V I Q R K E V Y I L L N W I G Y V N S G F N P L I Y C R S P D F Q E F R I A L L C
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Residue Table


GPCRdb(A)
GPCRdb(A)
β2-adrenoceptor
TM2
2x63 2.64x63 H93
TM3
3x28 3.28x28 W109
3x33 3.33x33 V114
ECL2
45x52 45.52x52 F193
TM5
5x43 5.42x43 S203
TM6
6x52 6.52x52 F290
TM7
7x42 7.43x42 Y316