Structure information

GABAB2

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

7C7Q

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

B

PUBLICATION DATE

July 1, 2020

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Baclofen W182 N-term aromatic (face-to-edge)
Baclofen S247 N-term polar (charge-assisted hydrogen bond)
Baclofen S247 N-term polar (charge-assisted hydrogen bond)
Baclofen S247 N-term polar (hydrogen bond with backbone)
Baclofen S270 N-term polar (charge-assisted hydrogen bond)
Baclofen H287 N-term polar (charge-assisted hydrogen bond)
Baclofen Y367 N-term aromatic (edge-to-face)
Baclofen Y367 N-term polar (charge-assisted hydrogen bond)
Baclofen E466 N-term polar (charge-charge)
BHFF M694 6.41x41 TM6 hydrophobic
BHFF Y789 aromatic (edge-to-face)
BHFF K792 polar (charge-assisted hydrogen bond)
BHFF K792 polar (charge-assisted hydrogen bond)
BHFF Y810 hydrophobic

Ligands

Baclofen

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BHFF

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Residue Diagrams

S A M I M G L I T L A S L I S Y L P L S 1 N L I I L G G M L S Y A S I F L F G L 2 A F M A G F A T T Y G V T L I W T R V T 3 L L V I V G G M L L I D L C I L I C W Q 4 A L F C G F L M L L G K Y A Y V I G L W 5 G M S V Y N V G I M C I I G A A V S F L 6 C L T I T S C F I I V L A V I C F Q V N 7
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ICL1 Q R N K L I K M S ICL1ECL1 D G S F V ECL1ICL2 N V K M K K K I I ICL2ECL2 P L R R T V E K Y S M E P D P A G R D I S I R P L L E H C E N T ECL2ICL3 S I P A L N ICL3ECL3 R D ECL3N-term M A S P R S S G Q P G P P P P P P P P P A R L L L L L L L P L L L P L A P G A W G W A R G A P R P P P S S P P L S I M G L M P L T K E V A K G S I G R G V L P A V E L A I E Q I R N E S L L R P Y F L D L R L Y D T E C D N A K G L K A F Y D A I K Y G P N H L M V F G G V C P S V T S I I A E S L Q G W N L V Q L S F A A T T P V L A D K K K Y P Y F F R T V P S D N A V N P A I L K L L K H Y Q W K R V G T L T Q D V Q R F S E V R N D L T G V L Y G E D I E I S D T E S F S N D P C T S V K K L K G N D V R I I L G Q F D Q N M A A K V F C C A Y E E N M Y G S K Y Q W I I P G W Y E P S W W E Q V H T E A N S S R C L R K N L L A A M E G Y I G V D F E P L S S K Q I K T I S G K T P Q Q Y E R E Y N N K R S G V G P S K F H G Y A Y D G I W V I A K T L Q R A M E T L H A S S R H Q R I Q D F N Y T D H T L G R I I L N A M N E T N F F G V T G Q V V F R N G E R M G T I K F T Q F Q D S R E V K V G E Y N A V A D T L E I I N D T I R F Q G S E P P K D K T I I L E Q L R K I N-termC-term T Q N Q K K E D S K T S T S V T S V N Q A S T S R L E G L Q S E N H R L R M K I T E L D K D L E E V T M Q L Q D T P E K T T Y I K Q N H Y Q E L N D I L N L G N F T E S T D G G K A I L K N H L D Q N P Q L Q W N T T E P S R T C K D P I E D I N S P E H I Q R R L S L Q L P I L H H A Y L P S I G G V D A S C V S P C V S P T A S P R H R H V P P S F R V M V S G L C-term S L P L Y S I L S A L T I L G M I M A S A F L F F N I K N S P Y M N N L I I L G G M L S Y A S I F L F G L S E K T F E T L C T V R T W I L T V G Y T T A F G A M F A K T W R V H A I F K K D Q K L L V I V G G M L L I D L C I L I C W Q A V D H M T I W L G I V Y A Y K G L L M L F G C F L A W E T R N V D S K Y I G M S V Y N V G I M C I I G A A V S F L T Q P N V Q F C I V A L V I I F C S T I T L C L V F V P K L I T L R T N P D A R R F A T Q N Q F
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Residue Table


GPCRdb(A)
GPCRdb(C)
GABAB2
TM6
6x39 6.41x41 M694