Structure information

D2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7DFP

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

A

PUBLICATION DATE

Dec. 30, 2020

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Spiperone V91 2.61x60 TM2 hydrophobic
Spiperone L94 2.64x63 TM2 hydrophobic
Spiperone V111 3.29x29 TM3 hydrophobic
Spiperone D114 3.32x32 TM3 polar (charge-charge)
Spiperone C118 3.36x36 TM3 hydrophobic
Spiperone W386 6.48x48 TM6 aromatic (face-to-edge)
Spiperone F390 6.52x52 TM6 aromatic (edge-to-face)

Ligands

Spiperone

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

V N G F V I V A I L L T L L T A Y Y N Y 1 V S L A V A D L L V A L T V M P W V V Y L 2 A C L N L I S A T C M M V D L T V F I D 3 V T V M I S I V W V L S F T I S C P L 4 Y V L L T V I F P V Y F S V I S S Y V V F 5 A I V L G V F I I C W L P F F I T H I L 6 I P N V A S N V Y G L W T F A S Y L V 7
Download: PNG | SVG
ICL1 K A L Q ICL1ECL1 E W K F ECL1ICL2 P M L Y N ICL2ECL2 L N N A D Q N E C I I A ECL2ICL3 R S S R A F R A H L R A P L K G N C T H P E D M K L C T V I M K S N G S F P V N R R R V E A A R R A Q E L E M E M L S S T S P P E R T R Y S P I P P S H H Q L T L P D P S H H G L H S T P D S P A K P E K N G H A K D H P K I A K I F E I Q T M P N G K T R T S L K T M S R R ICL3ECL3 D C N I ECL3N-term M D P L N L S W Y D D D L E R Q N W S R P F N G S D G K A D N-termC-term C C-term R P H Y N Y Y A T L L T L L I A V I V F G N V L V C M A V S R E T T T N Y L I V S L A V A D L L V A T L V M P W V V Y L E V V G S R I H C D I F V T L D V M M C T A S I L N L C A I S I D R Y T A V A M T R Y S S K R R V T V M I S I V W V L S F T I S C P L L F G N P A F V V Y S S I V S F Y V P F I V T L L V Y I K I Y I V L R R R R K R V N T K K L S Q Q K E K K A T Q M L A I V L G V F I I C W L P F F I T H I L N I H C P P V L Y S A F T W L G Y V N S A V N P I I Y T T F N I E F L K F R K A I L H
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
D2 receptor
TM2
2x60 2.61x60 V91
2x63 2.64x63 L94
TM3
3x29 3.29x29 V111
3x32 3.32x32 D114
3x36 3.36x36 C118
TM6
6x48 6.48x48 W386
6x52 6.52x52 F390