Structure information

mGlu1 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

7DGE

SPECIES

Homo sapiens

RESOLUTION

3.650

PREFERRED CHAIN

A

REFERENCE

10.1007/S13238-020-00808-5

PUBLICATION DATE

Sept. 22, 2021
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
quisqualate Y74 N-term aromatic (edge-to-face)
quisqualate Y74 N-term polar (hydrogen bond)
quisqualate Y74 N-term polar (hydrogen bond)
quisqualate Y74 N-term Van der Waals
quisqualate W110 N-term Van der Waals
quisqualate W110 N-term hydrophobic
quisqualate G163 N-term Van der Waals
quisqualate G163 N-term polar (hydrogen bond with backbone)
quisqualate S164 N-term Van der Waals
quisqualate S165 N-term polar (hydrogen bond)
quisqualate S165 N-term polar (hydrogen bond with backbone)
quisqualate S165 N-term polar (hydrogen bond)
quisqualate S186 N-term polar (hydrogen bond)
quisqualate S186 N-term Van der Waals
quisqualate A187 N-term Van der Waals
quisqualate T188 N-term polar (hydrogen bond)
quisqualate T188 N-term polar (hydrogen bond with backbone)
quisqualate T188 N-term polar (hydrogen bond)
quisqualate Y236 N-term hydrophobic
quisqualate Y236 N-term Van der Waals
quisqualate E292 N-term Van der Waals
quisqualate G293 N-term polar (hydrogen bond with backbone)
quisqualate G293 N-term Van der Waals
quisqualate D318 N-term polar (charge-assisted hydrogen bond)
quisqualate G319 N-term Van der Waals
quisqualate R323 N-term polar (charge-assisted hydrogen bond)
quisqualate K409 N-term Van der Waals
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 27 of 27 entries

Ligands

quisqualate

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Residue Diagrams

L T V L I G L C S F A I A I I S E I 1 Y I I L A G I F L G Y V C P F T L I A 2 T V L A S Y C M A S S L G V L L R Q L Y 3 Q V I I A S I L I S V Q L T L V V T L I 4 A Y Y T C S M I L L G N Y G L P A V V G 5 A F T M Y T T C I I W L A F V P I Y F G 6 G L A V T V S L S V A F C T T I I K Y 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term I E S I I A I A F S C L G I L V T L F V T L I F V L Y S R E L C Y I I L A G I F L G Y V C P F T L I A T T T S C Y L Q R L L V G L S S A M C Y S A L V T K T N R I A R I L S A W A Q V I I A S I L I S V Q L T L V V T L I I M E S N L G V V A P L G Y N G L L I M S C T Y Y A F K T E A K Y I A F T M Y T T C I I W L A F V P I Y F G S Y K I I T T C F A V S L S V T V A L G C M F T P K M Y I I I A K P E R A F T N V R S T S
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Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu1 receptor