PDB
7EUO
Resolution
2.9 Å
Released
May 25, 2022
Receptor
FPR1
Class
A
Species
Homo sapiens
Ligand
fMet-Leu-Phe
Function
Agonist
Reference
10.1038/S41467-022-32822-Y

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
fMet-Leu-Phe D106 3.33x33 TM3 polar (charge-assisted hydrogen bond)
fMet-Leu-Phe L109 3.36x36 TM3 hydrophobic
fMet-Leu-Phe L109 3.36x36 TM3 Van der Waals
fMet-Leu-Phe F110 3.37x37 TM3 Van der Waals
fMet-Leu-Phe F110 3.37x37 TM3 hydrophobic
fMet-Leu-Phe L198 5.35x36 TM5 hydrophobic
fMet-Leu-Phe R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
fMet-Leu-Phe R205 5.42x43 TM5 polar (charge-assisted hydrogen bond)
fMet-Leu-Phe W254 6.48x48 TM6 hydrophobic
fMet-Leu-Phe Y257 6.51x51 TM6 polar (hydrogen bond)
fMet-Leu-Phe Y257 6.51x51 TM6 polar (hydrogen bond)
fMet-Leu-Phe V283 7.35x34 TM7 Van der Waals
fMet-Leu-Phe V283 7.35x34 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 T H ICL1ECL1 G H W P F ECL1ICL2 P V W T Q N H R ICL2ECL2 T T V P G K T G T V A C T F N F S P W T N ECL2ICL3 L I K S ICL3ECL3 I R E L L Q G M ECL3N-term M E T N S S L P T N I S G G T P A V N-termC-term P A S L E R A L T E D S T Q T S D T A T N S T L P S A E V E L Q A K C-term S A G Y L F L D I I T Y L V F A V T F V L G V L G N G L V I W V A G F R M T V T T I S Y L N L A V A D F C F T S T L P F F M V R K A M G G W F L C K F V F T I V D I N L F G S V F L I A L I A L D R C V C V L H T V S L A K K V I I G P W V M A L L L T L P V I I R V D P K E R I N V A V A M L T V R G I I R F I I G F S A P M S I V A V S Y G L I A T K I H K Q G S R P L R V L S F V A A A F F L C W S P Y Q V V A L I A T V R Y K E I G I A V D V T S A L A F F N S C L N P M L Y V F M G Q D L I H F R E R A L
Helix box plot — Download: PNG | SVG G N G L V G L V F T V A F V L Y T I I D 1 L N L A V A D F C F T S T L P F F M V R 2 L A I L F V S G F L N I D V I T F V F K 3 A K K V I I G P W V M A L L L T L P V 4 Y S V A V I S M P A S F G I I F R I I G R 5 S F V A A A F F L C W S P Y Q V V A L I 6 M P N L C S N F F A L A S T V D V A I 7

GPCRdb(A)
GPCRdb(A)
FPR1
TM3
3x33 3.33x33 D106
3x36 3.36x36 L109
3x37 3.37x37 F110
TM5
5x36 5.35x36 L198
5x39 5.38x39 R201
5x43 5.42x43 R205
TM6
6x48 6.48x48 W254
6x51 6.51x51 Y257
TM7
7x34 7.35x34 V283