Structure information

S1P3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7EW4

SPECIES

Homo sapiens

RESOLUTION

3.200

PREFERRED CHAIN

R

PUBLICATION DATE

Sept. 29, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CYM-5541 F119 3.33x33 TM3 aromatic (face-to-edge)
CYM-5541 L122 3.36x36 TM3 hydrophobic
CYM-5541 L168 4.56x56 TM4 hydrophobic
CYM-5541 C200 5.43x43 TM5 hydrophobic
CYM-5541 I201 5.44x44 TM5 hydrophobic
CYM-5541 F204 5.47x47 TM5 hydrophobic
CYM-5541 F263 6.55x55 TM6 aromatic (edge-to-face)

Ligands

CYM-5541

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Residue Diagrams

L N E L V I F S C I V L F L V T T L T S 1 G N L A L C D L L A G I A Y K V N I L M 2 A L L S C T S A G L A V F M S G E R L F 3 V F L L I G M C W L I A F T L G A L P I 4 Y L I V I T V L I A T F I S I C F A I Y 5 V I V V S V F I A C W S P L F I L F L I 6 V P N M A S N L V A L V I F W Q A K F 7
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ICL1 N K F H ICL1ECL1 G K K T F S L ECL1ICL2 M R P Y D A N ICL2ECL2 W N C L H N L P D C S T I L P L Y ECL2ICL3 V A ICL3ECL3 R V Q A C ECL3N-term M A T A L P P R L Q P V R G N E T L R E H Y Q Y V G K L A G R L K E A S E G N-termC-term N C L V R G R G A R A S P I Q P A L D P S R S K S S S S N N S S H S P K V K E D L P H T A P S S C I M D K N A A L Q N G I F C N C-term S T L T T V L F L V I C S F I V L E N L M V L I A I W K N N R M Y F F I G N L A L C D L L A G I A Y K V N I L M S S P T V W F L R E G S M F V A L G A S T C S L L A I A I E R H L T M I K K R H R V F L L I G M C W L I A F T L G A L P I L G S K K Y I A F C I S I F T A I L V T I V I L Y A R I Y F L V K S S S R K N H N N S E R S M A L L R T V V I V V S V F I A C W S P L F I L F L I D V A C P I L F K A Q W F I V L A V L N S A M N P V I Y T L A S K E F F R M R R A L V C
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Residue Table


GPCRdb(A)
GPCRdb(A)
S1P3 receptor
TM3
3x33 3.33x33 F119
3x36 3.36x36 L122
TM4
4x56 4.56x56 L168
TM5
5x43 5.43x43 C200
5x44 5.44x44 I201
5x47 5.47x47 F204
TM6
6x55 6.55x55 F263