Structure information

CCK1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7F8U

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

A

REFERENCE

10.1038/S41589-021-00866-8

PUBLICATION DATE

Oct. 13, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
lintitript M121 3.32x32 TM3 hydrophobic
lintitript Y176 4.60x61 TM4 hydrophobic
lintitript I329 6.51x51 TM6 hydrophobic
lintitript F330 6.52x52 TM6 aromatic (face-to-edge)
lintitript N333 6.55x55 TM6 polar (hydrogen bond)
lintitript N333 6.55x55 TM6 polar (hydrogen bond)
lintitript R336 6.58x58 TM6 polar (charge-assisted hydrogen bond)
lintitript A343 ECL3 Van der Waals
lintitript A343 ECL3 hydrophobic
lintitript E344 ECL3 Van der Waals
lintitript L347 ECL3 hydrophobic
lintitript L347 ECL3 Van der Waals
lintitript I352 7.35x34 TM7 hydrophobic
lintitript I352 7.35x34 TM7 Van der Waals
lintitript L356 7.39x38 TM7 Van der Waals

Ligands

lintitript

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Residue Diagrams

T N G L V S L L F I L S Y L L I Q V A P 1 L S L A V S D L M L C F L C M P F N L I P 2 A V L N F T S V S V S T G M F Y T T T K 3 A L K V I A A T W C L S F T I M T P Y 4 Y A V M M V I G P I L F L I L L L F T H W 5 I V I V V L F F L C W M P I F S A N A W 6 I P N V C S S T Y S L L L I F S I P T 7
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ICL1 K R M R ICL1ECL1 D F I F ECL1ICL2 P L Q S R V W Q ICL2ECL2 N L V P F T K N N N Q T A N M C R F L L P ECL2ICL3 Q K K S A K E R K P S T T S S G K Y E D S D G C Y L Q K T R P P R K L E L R Q L S T G S S S R A N R I R S N S ICL3ECL3 T A S A E R R L S ECL3N-term M D V V D S L L V N G S N I T P P C E L G L E N E T L F C L D Q P R P S K E N-termC-term P G P P G A R G E V G E E E E G G T T G A S L S R F S Y S H M S A S V P P Q C-term W Q P A V Q I L L Y S L I F L L S V L G N T L V I T V L I R N T V T N I F L L S L A V S D L M L C L F C M P F N L I P N L L K G S A V C K T T T Y F M G T S V S V S T F N L V A I S L E R Y G A I C K T K S H A L K V I A A T W C L S F T I M T P Y P I Y S N D V M Q Q S W H T F L L L I L F L I P G I V M M V A Y G L I S L E L Y Q G I K F E A S S A A N L M A K K R V I R M L I V I V V L F F L C W M P I F S A N A W R A Y D G T P I S F I L L L S Y T S S C V N P I I Y C F M N K R F M A C P N F R L G T F P C
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Residue Table


GPCRdb(A)
GPCRdb(A)
CCK1 receptor
TM3
3x32 3.32x32 M121
TM4
4x61 4.60x61 Y176
TM6
6x51 6.51x51 I329
6x52 6.52x52 F330
6x55 6.55x55 N333
6x58 6.58x58 R336
TM7
7x34 7.35x34 I352
7x38 7.39x38 L356